Activation of the promoters of genes associated with DNA damage, oxidative stress, ER stress and protein malfolding by the bile salt, deoxycholate

Toxicology Letters

Volumn 108, Issue 1, 1999, Pages 37-46

  Bernstein, Harris ^a   Payne, Claire M ^a   Bernstein, Carol ^a   Schneider, John ^b   Beard, Shannon E ^b   Crowley, Cara L ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b Xenometrix Inc USA   (United States)

Author keywords

C fos; Cholestasis; Deoxycholate; Gadd153; Grp78; Hsp70; NF B

Indexed keywords

DEOXYCHOLIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

APOPTOSIS; ARTICLE; CELL GROWTH; CELL STRAIN HEPG2; CHOLESTASIS; CONTROLLED STUDY; DNA DAMAGE; GENE ACTIVATION; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER INJURY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FOLDING;

BILE ACIDS AND SALTS; CARRIER PROTEINS; CELL DEATH; CELL LINE, TRANSFORMED; CELL SURVIVAL; DEOXYCHOLIC ACID; DNA DAMAGE; DNA LIGASES; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MOLECULAR CHAPERONES; OXIDATIVE STRESS; PROMOTER REGIONS (GENETICS); PROTEIN FOLDING; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033618443     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00113-7     Document Type: Article

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