-
1
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley SR, Schooley K, Smolak PJ, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995; 3: 673-682.
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
-
2
-
-
0030155964
-
Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA
-
Marsters SA, Pitti RM, Donahue CJ, Ruppert S, Bauer KD, Ashkenazi A. Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA. Curr Biol 1996; 6: 750-752.
-
(1996)
Curr Biol
, vol.6
, pp. 750-752
-
-
Marsters, S.A.1
Pitti, R.M.2
Donahue, C.J.3
Ruppert, S.4
Bauer, K.D.5
Ashkenazi, A.6
-
3
-
-
0031905817
-
Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage
-
Mariani SM, Krammer PH. Differential regulation of TRAIL and CD95 ligand in transformed cells of the T and B lymphocyte lineage. Eur J Immunol 1998; 28: 973-982.
-
(1998)
Eur J Immunol
, vol.28
, pp. 973-982
-
-
Mariani, S.M.1
Krammer, P.H.2
-
4
-
-
0036132652
-
Development, characterization and use of monoclonal antibodies against sTRAIL: Measurement of sTRAIL by ELISA
-
2002
-
Liabakk NB, Sundan A, Torp S, Aukrust P, Froland SS, Espevik T. Development, characterization and use of monoclonal antibodies against sTRAIL: Measurement of sTRAIL by ELISA. 2002; J Immunol Methods 2002; 259: 119-128.
-
(2002)
J Immunol Methods
, vol.259
, pp. 119-128
-
-
Liabakk, N.B.1
Sundan, A.2
Torp, S.3
Aukrust, P.4
Froland, S.S.5
Espevik, T.6
-
5
-
-
0034142219
-
A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL
-
Hymowitz SG, O'Connell MP, Ultsch MH, et al. A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL. Biochemistry 2000; 39: 633-640.
-
(2000)
Biochemistry
, vol.39
, pp. 633-640
-
-
Hymowitz, S.G.1
O'Connell, M.P.2
Ultsch, M.H.3
-
6
-
-
0033169230
-
2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity
-
Cha SS, Kim MS, Choi YH, et al. 2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity. Immunity 1999; 11: 253-261.
-
(1999)
Immunity
, vol.11
, pp. 253-261
-
-
Cha, S.S.1
Kim, M.S.2
Choi, Y.H.3
-
7
-
-
0034617304
-
Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL
-
Bodmer JL, Meier P, Tschopp J, Schneider P. Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL. J Biol Chem 2000; 275: 20632-20637.
-
(2000)
J Biol Chem
, vol.275
, pp. 20632-20637
-
-
Bodmer, J.L.1
Meier, P.2
Tschopp, J.3
Schneider, P.4
-
8
-
-
0030996297
-
The receptor for the cytotoxic ligand TRAIL
-
Pan G, O'Rourke K, Chinnaiyan AM, et al. The receptor for the cytotoxic ligand TRAIL. Science 1997; 276: 111-113.
-
(1997)
Science
, vol.276
, pp. 111-113
-
-
Pan, G.1
O'Rourke, K.2
Chinnaiyan, A.M.3
-
9
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
-
Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 1997; 277: 815-818.
-
(1997)
Science
, vol.277
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.F.3
Yu, G.4
Gentz, R.5
Dixit, V.M.6
-
10
-
-
0031406386
-
Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway
-
Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway. Immunity 1997; 7: 821-830.
-
(1997)
Immunity
, vol.7
, pp. 821-830
-
-
Chaudhary, P.M.1
Eby, M.2
Jasmin, A.3
Bookwalter, A.4
Murray, J.5
Hood, L.6
-
11
-
-
0031405585
-
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB
-
Schneider P, Thome M, Burns K, et al. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB. Immunity 1997; 7: 831-836.
-
(1997)
Immunity
, vol.7
, pp. 831-836
-
-
Schneider, P.1
Thome, M.2
Burns, K.3
-
12
-
-
0030770614
-
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL
-
MacFarlane M, Ahmad M, Srinivasula SM, Fernandes-Alnemri T, Cohen GM, Alnemri ES. Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL. J Biol Chem 1997; 272: 25417-25420.
-
(1997)
J Biol Chem
, vol.272
, pp. 25417-25420
-
-
MacFarlane, M.1
Ahmad, M.2
Srinivasula, S.M.3
Fernandes-Alnemri, T.4
Cohen, G.M.5
Alnemri, E.S.6
-
13
-
-
0030880548
-
TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL
-
Walczak H, Degli-Esposti MA, Johnson RS, et al. TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL. EMBO J 1997; 16: 5386-5397.
-
(1997)
EMBO J
, vol.16
, pp. 5386-5397
-
-
Walczak, H.1
Degli-Esposti, M.A.2
Johnson, R.S.3
-
14
-
-
0031239984
-
TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL
-
Screaton GR, Mongkolsapaya J, Xu XN, Cowper AE, McMichael AJ, Bell JI. TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL. Curr Biol 1997; 7: 693-696.
-
(1997)
Curr Biol
, vol.7
, pp. 693-696
-
-
Screaton, G.R.1
Mongkolsapaya, J.2
Xu, X.N.3
Cowper, A.E.4
McMichael, A.J.5
Bell, J.I.6
-
15
-
-
0030792712
-
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
-
Sheridan JP, Marsters SA, Pitti RM, et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 1997; 277: 818-821.
-
(1997)
Science
, vol.277
, pp. 818-821
-
-
Sheridan, J.P.1
Marsters, S.A.2
Pitti, R.M.3
-
16
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
Wu GS, Burns TF, McDonald ER, III, et al. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 1997; 17: 141-143.
-
(1997)
Nat Genet
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald E.R. III3
-
17
-
-
0031627483
-
Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): A new receptor protecting lymphocytes from the death ligand TRAIL
-
Mongkolsapaya J, Cowper AE, Xu XN, et al. Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): A new receptor protecting lymphocytes from the death ligand TRAIL. J Immunol 1998; 160: 3-6.
-
(1998)
J Immunol
, vol.160
, pp. 3-6
-
-
Mongkolsapaya, J.1
Cowper, A.E.2
Xu, X.N.3
-
18
-
-
0030869432
-
Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
-
Degli-Esposti MA, Smolak PJ, Walczak H, et al. Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J Exp Med 1997; 186: 1165-1170.
-
(1997)
J Exp Med
, vol.186
, pp. 1165-1170
-
-
Degli-Esposti, M.A.1
Smolak, P.J.2
Walczak, H.3
-
19
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
-
Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 1997; 277: 815-818.
-
(1997)
Science
, vol.277
, pp. 815-818
-
-
Pan, G.1
Ni, J.2
Wei, Y.F.3
Yu, G.4
Gentz, R.5
Dixit, V.M.6
-
20
-
-
0032489353
-
TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling
-
Pan G, Ni J, Yu G, Wei YF, Dixit VM. TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling. FEBS Lett 1998; 424: 41-45.
-
(1998)
FEBS Lett
, vol.424
, pp. 41-45
-
-
Pan, G.1
Ni, J.2
Yu, G.3
Wei, Y.F.4
Dixit, V.M.5
-
21
-
-
13144265771
-
A novel receptor for Apo2L/TRAIL contains a truncated death domain
-
Marsters SA, Sheridan JP, Pitti RM, et al. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr Biol 1997;7:1003-1006.
-
(1997)
Curr Biol
, vol.7
, pp. 1003-1006
-
-
Marsters, S.A.1
Sheridan, J.P.2
Pitti, R.M.3
-
22
-
-
0031414749
-
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
-
Degli-Esposti MA, Dougall WC, Smolak PJ, Waugh JY, Smith CA, Goodwin RG. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 1997; 7: 813-820.
-
(1997)
Immunity
, vol.7
, pp. 813-820
-
-
Degli-Esposti, M.A.1
Dougall, W.C.2
Smolak, P.J.3
Waugh, J.Y.4
Smith, C.A.5
Goodwin, R.G.6
-
23
-
-
7344233085
-
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
-
Emery JG, McDonnell P, Burke MB, et al. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem 1998; 273:14363-14367.
-
(1998)
J Biol Chem
, vol.273
, pp. 14363-14367
-
-
Emery, J.G.1
McDonnell, P.2
Burke, M.B.3
-
24
-
-
0034725664
-
Temperature sensitive differential affinity of TRAIL for its receptors: DR5 is the highest affinity receptor
-
Truneh A, Sharma S, Silverman C, et al. Temperature sensitive differential affinity of TRAIL for its receptors: DR5 is the highest affinity receptor. J Biol Chem 2000; 275: 23319-23326.
-
(2000)
J Biol Chem
, vol.275
, pp. 23319-23326
-
-
Truneh, A.1
Sharma, S.2
Silverman, C.3
-
25
-
-
0028866022
-
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
-
Grell M, Douni E, Wajant H, et al. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. Cell 1995; 83: 793-802.
-
(1995)
Cell
, vol.83
, pp. 793-802
-
-
Grell, M.1
Douni, E.2
Wajant, H.3
-
26
-
-
0032550366
-
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
-
Schneider P, Holler N, Bodmer JL, et al. Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med 1998; 187: 1205-1213.
-
(1998)
J Exp Med
, vol.187
, pp. 1205-1213
-
-
Schneider, P.1
Holler, N.2
Bodmer, J.L.3
-
27
-
-
0031452949
-
Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing
-
Suda T, Hashimoto H, Tanaka M, Ochi T, Nagata S. Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J Exp Med 1997; 186:2045-2050.
-
(1997)
J Exp Med
, vol.186
, pp. 2045-2050
-
-
Suda, T.1
Hashimoto, H.2
Tanaka, M.3
Ochi, T.4
Nagata, S.5
-
28
-
-
0034644697
-
The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation
-
Muhlenbeck F, Schneider P, Bodmer JL, et al. The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation. J Biol Chem 2000; 275: 32208-32213.
-
(2000)
J Biol Chem
, vol.275
, pp. 32208-32213
-
-
Muhlenbeck, F.1
Schneider, P.2
Bodmer, J.L.3
-
29
-
-
0035811587
-
Differential activation of TRAIL-R1 and -2 by soluble and membrane TRAIL allows selective surface antigen-directed activation of TRAIL-R2 by a soluble TRAIL derivative
-
Wajant H, Moosmayer D, Wuest T, et al. Differential activation of TRAIL-R1 and -2 by soluble and membrane TRAIL allows selective surface antigen-directed activation of TRAIL-R2 by a soluble TRAIL derivative. Oncogene 2001; 20: 4101-4106.
-
(2001)
Oncogene
, vol.20
, pp. 4101-4106
-
-
Wajant, H.1
Moosmayer, D.2
Wuest, T.3
-
30
-
-
0034037333
-
Apoptosis induced by death receptors
-
Schneider P, Tschopp J. Apoptosis induced by death receptors. Pharm Acta Helv 2000; 74: 281-286.
-
(2000)
Pharm Acta Helv
, vol.74
, pp. 281-286
-
-
Schneider, P.1
Tschopp, J.2
-
31
-
-
0033790715
-
TRAIL receptor-2 signals apoptosis through FADD and caspase-8
-
Bodmer JL, Holler N, Reynard S, et al. TRAIL receptor-2 signals apoptosis through FADD and caspase-8. Nat Cell Biol 2000;2:241-243.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 241-243
-
-
Bodmer, J.L.1
Holler, N.2
Reynard, S.3
-
32
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor
-
Sprick MR, Weigand MA, Rieser E, et al. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor. Immunity 2000;12:599-609.
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
Weigand, M.A.2
Rieser, E.3
-
33
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
Kischkel FC, Lawrence DA, Chuntharapai A, Schow P, Kim KJ, Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 2000; 12: 611 -620.
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
34
-
-
0034682802
-
FADD is required for DR4- and DR5- mediated apoptosis: Lack of TRAIL-induced apoptosis in FADD-deficient mouse embryonic fibroblasts
-
Kuang AA, Diehl G, Zhang J, Winoto A. FADD is required for DR4- and DR5- mediated apoptosis: Lack of TRAIL-induced apoptosis in FADD-deficient mouse embryonic fibroblasts. J Biol Chem 2000; 275: 25065-25068.
-
(2000)
J Biol Chem
, vol.275
, pp. 25065-25068
-
-
Kuang, A.A.1
Diehl, G.2
Zhang, J.3
Winoto, A.4
-
35
-
-
0035374366
-
A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteins
-
Miyazaki T, Reed JC. A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteins. Nat Immunol 2001;2:493-500.
-
(2001)
Nat Immunol
, vol.2
, pp. 493-500
-
-
Miyazaki, T.1
Reed, J.C.2
-
36
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C, Fulda S, Srinivasan A, et al. Two CD95 (APO-1/Fas) signaling pathways. EMBO J 1998; 17: 1675-1687.
-
(1998)
EMBO J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
-
37
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H, Zhu H, Xu CJ, Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998; 94: 491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
38
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998; 94: 481-490.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
39
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
Chai J, Du C, WuJW, Kyin S, Wang X, Shi Y. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature 2000; 406: 855-862.
-
(2000)
Nature
, vol.406
, pp. 855-862
-
-
Chai, J.1
Du, C.2
Wu, J.W.3
Kyin, S.4
Wang, X.5
Shi, Y.6
-
40
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen AM, Ekert PG, Pakusch M, et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 2000; 102: 43-53.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
-
41
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei MC, Zong WX, Cheng EH, et al. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 2001; 292: 727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
-
42
-
-
0035890085
-
The expanding role of mitochondria in apoptosis
-
Wang X. The expanding role of mitochondria in apoptosis. Genes Dev 2001; 15: 2922-2933.
-
(2001)
Genes Dev
, vol.15
, pp. 2922-2933
-
-
Wang, X.1
-
43
-
-
0034737736
-
Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis
-
Tang D, Lahti JM, Kidd VJ. Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis. J Biol Chem 2000; 275: 9303-9307.
-
(2000)
J Biol Chem
, vol.275
, pp. 9303-9307
-
-
Tang, D.1
Lahti, J.M.2
Kidd, V.J.3
-
44
-
-
0034699353
-
Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis
-
Engels IH, Stepczynska A, Stroh C, et al. Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis. Oncogene 2000; 19: 4563-4573.
-
(2000)
Oncogene
, vol.19
, pp. 4563-4573
-
-
Engels, I.H.1
Stepczynska, A.2
Stroh, C.3
-
45
-
-
0035283079
-
Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs down-stream of caspase-3
-
Wieder T, Essmann F, Prokop A,etal. Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs down-stream of caspase-3. Blood 2001; 97: 1378-1387.
-
(2001)
Blood
, vol.97
, pp. 1378-1387
-
-
Wieder, T.1
Essmann, F.2
Prokop, A.3
-
46
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
47
-
-
0035394722
-
Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers
-
Shin MS, Kim HS, Lee SH, et al. Mutations of tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1) and receptor 2 (TRAIL-R2) genes in metastatic breast cancers. Cancer Res 2001; 61: 4942-4946.
-
(2001)
Cancer Res
, vol.61
, pp. 4942-4946
-
-
Shin, M.S.1
Kim, H.S.2
Lee, S.H.3
-
48
-
-
17744364468
-
Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma
-
Lee SH, Shin MS, Kim HS, et al. Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma. Oncogene 2001; 20: 399-403.
-
(2001)
Oncogene
, vol.20
, pp. 399-403
-
-
Lee, S.H.1
Shin, M.S.2
Kim, H.S.3
-
49
-
-
0034901512
-
Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer
-
Fisher MJ, Virmani AK, Wu L, et al. Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer. Clin Cancer Res 2001; 7:1688-1697.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1688-1697
-
-
Fisher, M.J.1
Virmani, A.K.2
Wu, L.3
-
50
-
-
0001130662
-
Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers
-
Lee SH, Shin MS, Kim HS, et al. Alterations of the DR5/TRAIL receptor 2 gene in non-small cell lung cancers. Cancer Res 1999; 59: 5683-5686.
-
(1999)
Cancer Res
, vol.59
, pp. 5683-5686
-
-
Lee, S.H.1
Shin, M.S.2
Kim, H.S.3
-
51
-
-
0034483069
-
TRAIL-R2 is not correlated with p53 status and is rarely mutated in non-small cell lung cancer
-
Wu WG, Soria JC, Wang L, Kemp BL, Mao L. TRAIL-R2 is not correlated with p53 status and is rarely mutated in non-small cell lung cancer. Anticancer Res 2000; 20: 4525-4529.
-
(2000)
Anticancer Res
, vol.20
, pp. 4525-4529
-
-
Wu, W.G.1
Soria, J.C.2
Wang, L.3
Kemp, B.L.4
Mao, L.5
-
52
-
-
0035008833
-
Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene
-
Guan B, Yue P, Clayman GL, Sun SY. Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene. J Cell Physiol 2001; 188: 98-105.
-
(2001)
J Cell Physiol
, vol.188
, pp. 98-105
-
-
Guan, B.1
Yue, P.2
Clayman, G.L.3
Sun, S.Y.4
-
53
-
-
0035253051
-
p53 upregulates cFLIP, inhibits transcription of NF-kappaB -regulated genes and induces caspase-8-independent cell death in DLD-1 cells
-
Bartke T, Siegmund D, Peters N, et al. p53 upregulates cFLIP, inhibits transcription of NF-kappaB -regulated genes and induces caspase-8-independent cell death in DLD-1 cells. Oncogene 2001; 20: 571-580.
-
(2001)
Oncogene
, vol.20
, pp. 571-580
-
-
Bartke, T.1
Siegmund, D.2
Peters, N.3
-
54
-
-
0034136792
-
The TRAIL decoy receptor TRUNDD (DcR2,TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis
-
Meng RD, McDonald ER, III, Sheikh MS, Fornace AJ, Jr., El Deiry WS. The TRAIL decoy receptor TRUNDD (DcR2,TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis. Mol Ther 2000; 1: 130-144.
-
(2000)
Mol Ther
, vol.1
, pp. 130-144
-
-
Meng, R.D.1
McDonald E.R. III2
Sheikh, M.S.3
Fornace A.J., Jr.4
El Deiry, W.S.5
-
55
-
-
0034732258
-
Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site
-
Takimoto R, El Deiry WS. Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site. Oncogene 2000; 19: 1735-1743.
-
(2000)
Oncogene
, vol.19
, pp. 1735-1743
-
-
Takimoto, R.1
El Deiry, W.S.2
-
56
-
-
0035851189
-
Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach
-
Burns TF, El Deiry WS. Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach. J Biol Chem 2001; 276: 37879-37886.
-
(2001)
J Biol Chem
, vol.276
, pp. 37879-37886
-
-
Burns, T.F.1
El Deiry, W.S.2
-
57
-
-
0018904051
-
Role of NK cells in tumour growth and metastasis in beige mice
-
Talmadge JE, Meyers KM, Prieur DJ, StarkeyJR. Role of NK cells in tumour growth and metastasis in beige mice. Nature 1980;284:622-624.
-
(1980)
Nature
, vol.284
, pp. 622-624
-
-
Talmadge, J.E.1
Meyers, K.M.2
Prieur, D.J.3
Starkey, J.R.4
-
58
-
-
0022616253
-
Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy
-
Karre K, Ljunggren HG, Piontek G, Kiessling R. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 1986; 319: 675-678.
-
(1986)
Nature
, vol.319
, pp. 675-678
-
-
Karre, K.1
Ljunggren, H.G.2
Piontek, G.3
Kiessling, R.4
-
59
-
-
0035137696
-
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
-
Takeda K, Hayakawa Y, Smyth MJ, et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nat Med 2001; 7: 94-100.
-
(2001)
Nat Med
, vol.7
, pp. 94-100
-
-
Takeda, K.1
Hayakawa, Y.2
Smyth, M.J.3
-
60
-
-
0036467427
-
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
-
Cretney E, Takeda K, Yagita H, Glaccum M, Peschon JJ, Smyth MJ. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J Immunol 2002; 168: 1356-1361.
-
(2002)
J Immunol
, vol.168
, pp. 1356-1361
-
-
Cretney, E.1
Takeda, K.2
Yagita, H.3
Glaccum, M.4
Peschon, J.J.5
Smyth, M.J.6
-
61
-
-
0035911242
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis
-
Smyth MJ, Cretney E, Takeda K, et al. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis. J Exp Med 2001; 193: 661-670.
-
(2001)
J Exp Med
, vol.193
, pp. 661-670
-
-
Smyth, M.J.1
Cretney, E.2
Takeda, K.3
-
62
-
-
0035313175
-
TRAIL expression by activated human CD4(+)V alpha 24NKT cells induces in vitro and in vivo apoptosis of human acute myeloid leukemia cells
-
Nieda M, Nicol A, Koezuka Y, et al. TRAIL expression by activated human CD4(+)V alpha 24NKT cells induces in vitro and in vivo apoptosis of human acute myeloid leukemia cells. Blood 2001; 97: 2067-2074.
-
(2001)
Blood
, vol.97
, pp. 2067-2074
-
-
Nieda, M.1
Nicol, A.2
Koezuka, Y.3
-
63
-
-
0035067368
-
Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB
-
Ravi R, Bedi GC, Engstrom LW, et al. Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB. Nat Cell Biol 2001; 3: 409-416.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 409-416
-
-
Ravi, R.1
Bedi, G.C.2
Engstrom, L.W.3
-
64
-
-
0035920230
-
Rel/NF-kappa B transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1
-
Bernard D, Quatannens B, Vandenbunder B, Abbadie C. Rel/NF-kappa B transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1. J Biol Chem 2001; 276: 27322-27328.
-
(2001)
J Biol Chem
, vol.276
, pp. 27322-27328
-
-
Bernard, D.1
Quatannens, B.2
Vandenbunder, B.3
Abbadie, C.4
-
65
-
-
0035963273
-
Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells
-
Oya M, Ohtsubo M, Takayanagi A, Tachibana M, Shimizu N, Murai M. Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells. Oncogene 2001; 20: 3888-3896.
-
(2001)
Oncogene
, vol.20
, pp. 3888-3896
-
-
Oya, M.1
Ohtsubo, M.2
Takayanagi, A.3
Tachibana, M.4
Shimizu, N.5
Murai, M.6
-
66
-
-
0035914394
-
Pro-survival function of Akt/protein kinase B in prostate cancer cells: Relationship with trail resistance
-
Thakkar H, Chen X, Tyan F, et al. Pro-survival function of Akt/protein kinase B in prostate cancer cells: Relationship with trail resistance. J Biol Chem 2001; 276: 38361-38369.
-
(2001)
J Biol Chem
, vol.276
, pp. 38361-38369
-
-
Thakkar, H.1
Chen, X.2
Tyan, F.3
-
67
-
-
0034904913
-
Differential effects of phosphatidylinositol-3/Akt-kinase inhibition on apoptotic sensitization to cytokines in LNCaP and PCc-3 prostate cancer cells
-
Beresford SA, Davies MA, Gallick GE, Donato NJ. Differential effects of phosphatidylinositol-3/Akt-kinase inhibition on apoptotic sensitization to cytokines in LNCaP and PCc-3 prostate cancer cells. J Inteferon Cytokine Res 2001; 21: 313-322.
-
(2001)
J Inteferon Cytokine Res
, vol.21
, pp. 313-322
-
-
Beresford, S.A.1
Davies, M.A.2
Gallick, G.E.3
Donato, N.J.4
-
68
-
-
0035831556
-
Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells
-
Panka DJ, Mano T, Suhara T, Walsh K, Mier JW. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells. J Biol Chem 2001; 276: 6893-6896.
-
(2001)
J Biol Chem
, vol.276
, pp. 6893-6896
-
-
Panka, D.J.1
Mano, T.2
Suhara, T.3
Walsh, K.4
Mier, J.W.5
-
69
-
-
0035921762
-
Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer
-
Chen X, Thakkar H, Tyan F, et al. Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer. Oncogene 2001; 20: 6073-6083.
-
(2001)
Oncogene
, vol.20
, pp. 6073-6083
-
-
Chen, X.1
Thakkar, H.2
Tyan, F.3
-
70
-
-
0037050231
-
PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway
-
Yuan XJ, Whang YE. PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway. Oncogene 2002; 21: 319-327.
-
(2002)
Oncogene
, vol.21
, pp. 319-327
-
-
Yuan, X.J.1
Whang, Y.E.2
-
71
-
-
0035874898
-
Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2
-
Cuello M, Ettenberg SA, Clark AS, et al. Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2. Cancer Res 2001; 61: 4892-4900.
-
(2001)
Cancer Res
, vol.61
, pp. 4892-4900
-
-
Cuello, M.1
Ettenberg, S.A.2
Clark, A.S.3
-
72
-
-
0035815649
-
Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis
-
Nesterov A, Lu X, Johnson M, Miller GJ, Ivashchenko Y, Kraft AS. Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis. J Biol Chem 2001;276:10767-10774.
-
(2001)
J Biol Chem
, vol.276
, pp. 10767-10774
-
-
Nesterov, A.1
Lu, X.2
Johnson, M.3
Miller, G.J.4
Ivashchenko, Y.5
Kraft, A.S.6
-
73
-
-
0035097350
-
Activation of protein kinase C inhibits TRAIL-induced caspases activation, mitochondrial events and apoptosis in a human leukemic T cell line
-
Sarker M, Ruiz-Ruiz C, Lopez-Rivas A. Activation of protein kinase C inhibits TRAIL-induced caspases activation, mitochondrial events and apoptosis in a human leukemic T cell line. Cell Death Differ 2001; 8: 172-181.
-
(2001)
Cell Death Differ
, vol.8
, pp. 172-181
-
-
Sarker, M.1
Ruiz-Ruiz, C.2
Lopez-Rivas, A.3
-
74
-
-
0035380994
-
Bcl-2 over-expression and activation of protein kinase C suppress the TRAIL-induced apoptosis in Jurkat T cells
-
Guo BC, Xu YH. Bcl-2 over-expression and activation of protein kinase C suppress the TRAIL-induced apoptosis in Jurkat T cells. Cell Res 2001; 11: 101-106.
-
(2001)
Cell Res
, vol.11
, pp. 101-106
-
-
Guo, B.C.1
Xu, Y.H.2
-
75
-
-
0034741269
-
A protective role of PKCepsilon against TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in glioma cells
-
Shinohara H, Kayagaki N, Yagita H, et al. A protective role of PKCepsilon against TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in glioma cells. Biochem Biophys Res Commun 2001; 284: 1162-1167.
-
(2001)
Biochem Biophys Res Commun
, vol.284
, pp. 1162-1167
-
-
Shinohara, H.1
Kayagaki, N.2
Yagita, H.3
-
76
-
-
17944379442
-
CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells
-
Trauzold A, Wermann H, Arlt A, et al. CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells. Oncogene 2001; 20: 42584269.
-
(2001)
Oncogene
, vol.20
, pp. 42584269
-
-
Trauzold, A.1
Wermann, H.2
Arlt, A.3
-
77
-
-
0035844129
-
MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors
-
Tran SE, Holmstrom TH, Ahonen M, Kahari VM, Eriksson JE. MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors. J Biol Chem 2001; 276: 16484-16490.
-
(2001)
J Biol Chem
, vol.276
, pp. 16484-16490
-
-
Tran, S.E.1
Holmstrom, T.H.2
Ahonen, M.3
Kahari, V.M.4
Eriksson, J.E.5
-
78
-
-
0034743199
-
NF-kappaB signals induce the expression of c-FLIP
-
Micheau O, Lens S, Gaide O, Alevizopoulos K, Tschopp J. NF-kappaB signals induce the expression of c-FLIP. Mol Cell Biol 2001; 21: 5299-5305.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5299-5305
-
-
Micheau, O.1
Lens, S.2
Gaide, O.3
Alevizopoulos, K.4
Tschopp, J.5
-
79
-
-
0034744033
-
NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling
-
Kreuz S, Siegmund D, Scheurich P, Wajant H. NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling. Mol Cell Biol 2001; 21: 3964-3973.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3964-3973
-
-
Kreuz, S.1
Siegmund, D.2
Scheurich, P.3
Wajant, H.4
-
80
-
-
0033174072
-
Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop
-
Levkau B, Scatena M, Giachelli CM, Ross R, Raines EW. Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-kappa B loop. Nat Cell Biol 1999;1:227-233.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 227-233
-
-
Levkau, B.1
Scatena, M.2
Giachelli, C.M.3
Ross, R.4
Raines, E.W.5
-
81
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin Y, Devin A, Rodriguez Y, Liu ZG. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 1999; 13: 2514-2526.
-
(1999)
Genes Dev
, vol.13
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.G.4
-
82
-
-
0033575220
-
Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpba that functions as a stable inhibitor of NF-kappaB
-
Reuther JY, Baldwin AS, Jr. Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpba that functions as a stable inhibitor of NF-kappaB. J Biol Chem 1999;274:20664-20670.
-
(1999)
J Biol Chem
, vol.274
, pp. 20664-20670
-
-
Reuther, J.Y.1
Baldwin A.S., Jr.2
-
83
-
-
0033966264
-
Caspase-induced inactivation of the anti-apoptotic TRAF1 during fas ligand-mediated apoptosis
-
Irmler M, Steiner V, Ruegg C, Wajant H, TschoppJ. Caspase-induced inactivation of the anti-apoptotic TRAF1 during fas ligand-mediated apoptosis. FEBS Lett 2000; 468: 129-133.
-
(2000)
FEBS Lett
, vol.468
, pp. 129-133
-
-
Irmler, M.1
Steiner, V.2
Ruegg, C.3
Wajant, H.4
Tschopp, J.5
-
84
-
-
0035805496
-
Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPKI) converts an activator of NFkappaB into an inhibitor of NFkappaB
-
Arnold R, Liou J, Drexler HC, Weiss A, Kiefer F. Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPKI) converts an activator of NFkappaB into an inhibitor of NFkappaB. J Biol Chem 2001; 276: 14675-14684.
-
(2001)
J Biol Chem
, vol.276
, pp. 14675-14684
-
-
Arnold, R.1
Liou, J.2
Drexler, H.C.3
Weiss, A.4
Kiefer, F.5
-
85
-
-
0034646478
-
Activation of NF-kappaB by FADD, Casper, and Caspase-8
-
Hu WH, Johnson H, Shu HB. Activation of NF-kappaB by FADD, Casper, and Caspase-8. J Biol Chem 2000; 275: 10838-10844.
-
(2000)
J Biol Chem
, vol.275
, pp. 10838-10844
-
-
Hu, W.H.1
Johnson, H.2
Shu, H.B.3
-
86
-
-
0035930326
-
Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis
-
Tang G, Yang J, Minemoto Y, Lin A. Blocking caspase-3-mediated proteolysis of IKKbeta suppresses TNF-alpha-induced apoptosis. Mol Cell 2001; 8: 1005-1016.
-
(2001)
Mol Cell
, vol.8
, pp. 1005-1016
-
-
Tang, G.1
Yang, J.2
Minemoto, Y.3
Lin, A.4
-
87
-
-
0035941235
-
Tumor necrosis factor (TNF) and phorbol ester induce TNF-related apoptosis-inducing ligand (TRAIL) under critical involvement of NF-kappa B essential modulator (NEMO)/IKKgamma
-
Siegmund D, Hausser A, Peters N, Scheurich P, Wajant H. Tumor necrosis factor (TNF) and phorbol ester induce TNF-related apoptosis-inducing ligand (TRAIL) under critical involvement of NF-kappa B essential modulator (NEMO)/IKKgamma.J Biol Chem 2001; 276:43708-43712.
-
(2001)
J Biol Chem
, vol.276
, pp. 43708-43712
-
-
Siegmund, D.1
Hausser, A.2
Peters, N.3
Scheurich, P.4
Wajant, H.5
-
88
-
-
0035798624
-
NF-kappaB signaling pathway governs TRAIL gene expression and human T-cell leukemia virus-I tax-induced T-cell death
-
Rivera-Walsh I, Waterfield M, Xiao G, Fong A, Sun SC. NF-kappaB signaling pathway governs TRAIL gene expression and human T-cell leukemia virus-I tax-induced T-cell death. J Biol Chem 2001; 276: 40385-40388.
-
(2001)
J Biol Chem
, vol.276
, pp. 40385-40388
-
-
Rivera-Walsh, I.1
Waterfield, M.2
Xiao, G.3
Fong, A.4
Sun, S.C.5
-
89
-
-
0035883162
-
Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression
-
Baetu TM, Kwon H, Sharma S, Grandvaux N, Hiscott J. Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression. J Immunol 2001; 167: 3164-3173.
-
(2001)
J Immunol
, vol.167
, pp. 3164-3173
-
-
Baetu, T.M.1
Kwon, H.2
Sharma, S.3
Grandvaux, N.4
Hiscott, J.5
-
90
-
-
0035195486
-
Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D
-
Olsson A, Diaz T, Aguilar-Santelises M, et al. Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D. Leukemia 2001; 15: 1868-1877.
-
(2001)
Leukemia
, vol.15
, pp. 1868-1877
-
-
Olsson, A.1
Diaz, T.2
Aguilar-Santelises, M.3
-
91
-
-
0034747649
-
Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin
-
Mizutani Y, Nakao M, Ogawa O, Yoshida O, Bonavida B, Miki T. Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin. J Urol 2001; 165:263-270.
-
(2001)
J Urol
, vol.165
, pp. 263-270
-
-
Mizutani, Y.1
Nakao, M.2
Ogawa, O.3
Yoshida, O.4
Bonavida, B.5
Miki, T.6
-
92
-
-
0034989624
-
In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity
-
Wuchter C, Krappmann D, Cai Z, et al. In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity. Leukemia 2001; 15: 921-928.
-
(2001)
Leukemia
, vol.15
, pp. 921-928
-
-
Wuchter, C.1
Krappmann, D.2
Cai, Z.3
-
93
-
-
0032717188
-
TRAIL is a potent inducer of apoptosis in myeloma cells derived from multiple myeloma patients and is not cytotoxic to hematopoietic stem cells
-
Gazitt Y. TRAIL is a potent inducer of apoptosis in myeloma cells derived from multiple myeloma patients and is not cytotoxic to hematopoietic stem cells. Leukemia 1999; 13: 1817-1824.
-
(1999)
Leukemia
, vol.13
, pp. 1817-1824
-
-
Gazitt, Y.1
-
94
-
-
0035437171
-
TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: Therapeutic applications
-
Mitsiades CS, Treon SP, Mitsiades N, et al. TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: Therapeutic applications. Blood 2001;98:795-804.
-
(2001)
Blood
, vol.98
, pp. 795-804
-
-
Mitsiades, C.S.1
Treon, S.P.2
Mitsiades, N.3
-
95
-
-
0034961181
-
Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL
-
Altucci L, Rossin A, Raffelsberger W, Reitmair A, Chomienne C, Gronemeyer H. Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL. Nat Med 2001; 7: 680-686.
-
(2001)
Nat Med
, vol.7
, pp. 680-686
-
-
Altucci, L.1
Rossin, A.2
Raffelsberger, W.3
Reitmair, A.4
Chomienne, C.5
Gronemeyer, H.6
-
96
-
-
0035950522
-
Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma
-
Toomey NL, Deyev VV, Wood C, et al. Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma. Oncogene 2001; 20: 7029-7040.
-
(2001)
Oncogene
, vol.20
, pp. 7029-7040
-
-
Toomey, N.L.1
Deyev, V.V.2
Wood, C.3
-
98
-
-
0030892234
-
Apoptosis by death factor
-
Nagata S. Apoptosis by death factor. Cell 1997; 88: 355-365.
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
99
-
-
0035403040
-
Isolated limb perfusion for extremity soft-tissue sarcomas, in-transit metastases, and other unresectable tumors: Credits, debits, and future perspectives
-
Eggermont AM, ten Hagen TL. Isolated limb perfusion for extremity soft-tissue sarcomas, in-transit metastases, and other unresectable tumors: Credits, debits, and future perspectives. Curr Oncol Rep 2001; 3: 359-367.
-
(2001)
Curr Oncol Rep
, vol.3
, pp. 359-367
-
-
Eggermont, A.M.1
Ten Hagen, T.L.2
-
100
-
-
0032910169
-
Apoptosis control by death and decoy receptors
-
Ashkenazi A, Dixit VM. Apoptosis control by death and decoy receptors. Cnrr Opin Cell Biol 1999; 11: 255-260.
-
(1999)
Curr Opin Cell Biol
, vol.11
, pp. 255-260
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
101
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
-
Lawrence D, Shahrokh Z, Marsters S, et al. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat Med 2001; 7: 383-385.
-
(2001)
Nat Med
, vol.7
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
-
102
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
Walczak H, Miller RE, Ariail K, et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 1999; 5: 157-163.
-
(1999)
Nat Med
, vol.5
, pp. 157-163
-
-
Walczak, H.1
Miller, R.E.2
Ariail, K.3
-
103
-
-
0034022160
-
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
-
Jo M, Kim TH, Seol DW, et al. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med 2000; 6: 564-567.
-
(2000)
Nat Med
, vol.6
, pp. 564-567
-
-
Jo, M.1
Kim, T.H.2
Seol, D.W.3
-
104
-
-
17944376030
-
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
-
Ichikawa K, Liu W, Zhao L, et al. Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med 2001; 7: 954-960.
-
(2001)
Nat Med
, vol.7
, pp. 954-960
-
-
Ichikawa, K.1
Liu, W.2
Zhao, L.3
-
105
-
-
0033975513
-
Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes
-
Leverkus M, Neumann M, Mengling T, et al. Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes. Cancer Res 2000; 60: 553-559.
-
(2000)
Cancer Res
, vol.60
, pp. 553-559
-
-
Leverkus, M.1
Neumann, M.2
Mengling, T.3
-
107
-
-
85047697089
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis in normal prostate epithelial cells
-
Nesterov A, Ivashchenko Y, Kraft AS. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis in normal prostate epithelial cells. Oncogene 2002; 21: 1135-1140.
-
(2002)
Oncogene
, vol.21
, pp. 1135-1140
-
-
Nesterov, A.1
Ivashchenko, Y.2
Kraft, A.S.3
-
108
-
-
0034781511
-
Analysis of the oligomeric requirement for signaling by CD40 using soluble multimeric forms of its ligand, CD154
-
Haswell LE, Glennie MJ, Al Shamkhani A. Analysis of the oligomeric requirement for signaling by CD40 using soluble multimeric forms of its ligand, CD154. Eur J Immunol 2001; 31:3094-3100.
-
(2001)
Eur J Immunol
, vol.31
, pp. 3094-3100
-
-
Haswell, L.E.1
Glennie, M.J.2
Al Shamkhani, A.3
-
109
-
-
0034908231
-
Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis
-
Hernandez A, Thomas R, Smith F, et al. Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis. Surgery, 2001;130:265-272.
-
(2001)
Surgery
, vol.130
, pp. 265-272
-
-
Hernandez, A.1
Thomas, R.2
Smith, F.3
-
110
-
-
0035932369
-
Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria-dependent pathway in human colorectal carcinoma CX-I cells
-
Lee YJ, Lee KH, Kim HR, et al. Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria-dependent pathway in human colorectal carcinoma CX-I cells. Oncogene 2001; 20: 1476-1485.
-
(2001)
Oncogene
, vol.20
, pp. 1476-1485
-
-
Lee, Y.J.1
Lee, K.H.2
Kim, H.R.3
-
112
-
-
0035866369
-
Anticancer agents sensitize tumor cells to tumor necrosis facror-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis
-
Lacour S, Hammann A, Wotawa A, Corcos L, Solary E, Dimanche-Boitrel MT. Anticancer agents sensitize tumor cells to tumor necrosis facror-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis. Cancer Res 2001; 61: 1645-1651.
-
(2001)
Cancer Res
, vol.61
, pp. 1645-1651
-
-
Lacour, S.1
Hammann, A.2
Wotawa, A.3
Corcos, L.4
Solary, E.5
Dimanche-Boitrel, M.T.6
-
113
-
-
0033572413
-
Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11
-
Gliniak B, Le T. Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11. Cancer Res 1999; 59: 6153-6158.
-
(1999)
Cancer Res
, vol.59
, pp. 6153-6158
-
-
Gliniak, B.1
Le, T.2
-
114
-
-
0034574785
-
The use of TNF family ligands and receptors and agents which modify their interaction as therapeutic agents
-
Gardnerova M, Blanque R, Gardner CR. The use of TNF family ligands and receptors and agents which modify their interaction as therapeutic agents. Curr Drug Targets 2000; 1: 327-364.
-
(2000)
Curr Drug Targets
, vol.1
, pp. 327-364
-
-
Gardnerova, M.1
Blanque, R.2
Gardner, C.R.3
-
115
-
-
0035674729
-
Adriamycin sensitizes the adriamycin-resistant 8226/Dox40 human multiple myeloma cells to Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-mediated (TRAIL) apoptosis
-
Jazirehi AR, Ng CP, Gan XH, Schiller G, Bonavida B. Adriamycin sensitizes the adriamycin-resistant 8226/Dox40 human multiple myeloma cells to Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-mediated (TRAIL) apoptosis. Clin Cancer Res 2001; 7: 3874-3883.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3874-3883
-
-
Jazirehi, A.R.1
Ng, C.P.2
Gan, X.H.3
Schiller, G.4
Bonavida, B.5
-
116
-
-
0035849785
-
CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release
-
Rohn TA, Wagenknecht B, Roth W, etal. CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release. Oncogene 2001; 20: 4128-4137.
-
(2001)
Oncogene
, vol.20
, pp. 4128-4137
-
-
Rohn, T.A.1
Wagenknecht, B.2
Roth, W.3
-
117
-
-
0034652486
-
Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo
-
Nagane M, Pan G, Weddle JJ, Dixit VM, Cavenee WK, Huang HJ. Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo. Cancer Res 2000; 60: 847-853.
-
(2000)
Cancer Res
, vol.60
, pp. 847-853
-
-
Nagane, M.1
Pan, G.2
Weddle, J.J.3
Dixit, V.M.4
Cavenee, W.K.5
Huang, H.J.6
-
118
-
-
0036137141
-
Trail activity in human ovarian cancer cells: Potentiation of the action of cytotoxic drugs
-
Vignati S, Codegoni A, Polato F, Broggini M. Trail activity in human ovarian cancer cells: Potentiation of the action of cytotoxic drugs. Eur J Cancer 2002; 38: 177-183.
-
(2002)
Eur J Cancer
, vol.38
, pp. 177-183
-
-
Vignati, S.1
Codegoni, A.2
Polato, F.3
Broggini, M.4
-
119
-
-
0034985464
-
Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells
-
Cuello M, Ettenberg SA, Nau MM, Lipkowitz S. Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells. Gynecol Oncol 2001; 81: 380-390.
-
(2001)
Gynecol Oncol
, vol.81
, pp. 380-390
-
-
Cuello, M.1
Ettenberg, S.A.2
Nau, M.M.3
Lipkowitz, S.4
-
120
-
-
0033083990
-
Chemotherapy augments TRAIL-induced apoptosis in breast cell lines
-
Keane MM, Ettenberg SA, Nau MM, Russell EK, Lipkowitz S. Chemotherapy augments TRAIL-induced apoptosis in breast cell lines. Cancer Res 1999; 59: 734-741.
-
(1999)
Cancer Res
, vol.59
, pp. 734-741
-
-
Keane, M.M.1
Ettenberg, S.A.2
Nau, M.M.3
Russell, E.K.4
Lipkowitz, S.5
-
121
-
-
0034652156
-
Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy
-
Chinnaiyan AM, Prasad U, Shankar S, et al. Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad Sci USA 2000; 97: 1754-1759.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1754-1759
-
-
Chinnaiyan, A.M.1
Prasad, U.2
Shankar, S.3
-
122
-
-
0035912109
-
Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL
-
Belka C, Schmid B, Marini P, et al. Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL. Oncogene 2001; 20: 2190-2196.
-
(2001)
Oncogene
, vol.20
, pp. 2190-2196
-
-
Belka, C.1
Schmid, B.2
Marini, P.3
-
123
-
-
0034667482
-
Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionizing radiation in leukemic cells
-
Gong B, Almasan A. Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionizing radiation in leukemic cells. Cancer Res 2000; 60: 5754-5760.
-
(2000)
Cancer Res
, vol.60
, pp. 5754-5760
-
-
Gong, B.1
Almasan, A.2
-
124
-
-
0035866396
-
Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression
-
Eggert A, Grotzer MA, Zuzak TJ, et al. Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression. Cancer Res 2001; 61: 1314-1319.
-
(2001)
Cancer Res
, vol.61
, pp. 1314-1319
-
-
Eggert, A.1
Grotzer, M.A.2
Zuzak, T.J.3
-
125
-
-
0034699330
-
Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression
-
Grotzer MA, Eggert A, Zuzak TJ, et al. Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression. Oncogene 2000; 19: 4604-4610.
-
(2000)
Oncogene
, vol.19
, pp. 4604-4610
-
-
Grotzer, M.A.1
Eggert, A.2
Zuzak, T.J.3
-
126
-
-
0035120415
-
Combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells
-
Matsuzaki H, Schmied BM, Ulrich A, et al. Combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells. Clin Cancer Res 2001; 7: 407-414.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 407-414
-
-
Matsuzaki, H.1
Schmied, B.M.2
Ulrich, A.3
-
127
-
-
0035126944
-
Cotreatment with STI-571 enhances tumor necrosis factor alpha-related apoptosis-inducing ligand (TRAIL or apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells
-
Nimmanapalli R, Porosnicu M, Nguyen D, et al. Cotreatment with STI-571 enhances tumor necrosis factor alpha-related apoptosis-inducing ligand (TRAIL or apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells. Clin Cancer Res 2001; 7: 350-357.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 350-357
-
-
Nimmanapalli, R.1
Porosnicu, M.2
Nguyen, D.3
-
128
-
-
0035863523
-
Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels
-
Nimmanapalli R, Perkins CL, Orlando M, O'Bryan E, Nguyen D, Bhalla KN. Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels. Cancer Res 2001; 61: 759-763.
-
(2001)
Cancer Res
, vol.61
, pp. 759-763
-
-
Nimmanapalli, R.1
Perkins, C.L.2
Orlando, M.3
O'Bryan, E.4
Nguyen, D.5
Bhalla, K.N.6
-
129
-
-
0036167572
-
Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL
-
Voelkel-Johnson C, King DL, Norris JS. Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL. Cancer Gene Ther 2002; 9: 164-172.
-
(2002)
Cancer Gene Ther
, vol.9
, pp. 164-172
-
-
Voelkel-Johnson, C.1
King, D.L.2
Norris, J.S.3
-
130
-
-
0033710429
-
Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan
-
Dejosez M, Ramp U, Mahotka C, et al. Sensitivity to TRAIL/APO-2L-mediated apoptosis in human renal cell carcinomas and its enhancement by topotecan. Cell Death Differ 2000; 7: 1127-1136.
-
(2000)
Cell Death Differ
, vol.7
, pp. 1127-1136
-
-
Dejosez, M.1
Ramp, U.2
Mahotka, C.3
-
131
-
-
0036138282
-
Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil
-
Mizutani Y, Nakanishi H, Yoshida O, Fukushima M, Bonavida B, Miki T. Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil. Eur J Cancer 2002; 38: 167-176.
-
(2002)
Eur J Cancer
, vol.38
, pp. 167-176
-
-
Mizutani, Y.1
Nakanishi, H.2
Yoshida, O.3
Fukushima, M.4
Bonavida, B.5
Miki, T.6
-
132
-
-
0033839749
-
Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines
-
Yamanaka T, Shiraki K, Sugimoto K, etal. Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines. Hepatology 2000; 32: 482-490.
-
(2000)
Hepatology
, vol.32
, pp. 482-490
-
-
Yamanaka, T.1
Shiraki, K.2
Sugimoto, K.3
-
133
-
-
0033809089
-
Apoptotic responsiveness of the Ewing's sarcoma family of tumours to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)
-
Van Valen F, Fulda S, Truckenbrod B, etal. Apoptotic responsiveness of the Ewing's sarcoma family of tumours to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL). Int J Cancer 2000; 88: 252-259.
-
(2000)
Int J Cancer
, vol.88
, pp. 252-259
-
-
Van Valen, F.1
Fulda, S.2
Truckenbrod, B.3
|