TRAIL expression by activated human CD4+Vα24NKT cells induces in vitro and in vivo apoptosis of human acute myeloid leukemia cells

Blood

Volumn 97, Issue 7, 2001, Pages 2067-2074

  Nieda, Mie ^a   Nicol, Andrew ^b   Koezuka, Yashuhiko ^b   Kikuchi, Akiko ^b   Lapteva, Natalia ^b   Tanaka, Yuji ^b   Tokunaga, Katsushi ^b   Suzuki, Kenji ^b   Kayagaki, Nobuhiko ^b   Yagita, Hideo ^b   Hirai, Hisamaru ^b   Juji, Takeo ^b  

^a JAPANESE RED CROSS MEDICAL CENTER   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD1 ANTIGEN; CD4 ANTIGEN; GALACTOSYLCERAMIDE; NEUTRALIZING ANTIBODY; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ACUTE GRANULOCYTIC LEUKEMIA; ADOPTIVE IMMUNOTHERAPY; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL ACTIVATION; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0035313175     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V97.7.2067     Document Type: Article

References (34)

1. CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides
2. CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells
3. Activation of human Valpha24NKT cells by alpha-glycosylceramide in a CD1d-restricted and Valpha24TCR-mediated manner
4. Requirements for CD1d recognition by human invariant Valpha24+ CD4-CD8- T cells
5. Treatment of hepatic metastasis of the colon26 adenocarcinoma with an alpha-galactosylceramide, KRN7000
6. Structure-activity relationship of alpha-galactosylceramides against B16-bearing mice
7. Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors
8. Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cells
9. Human invariant valpha24+ natural killer T cells activated by alpha-galactosylceramide (KRN7000) have cytotoxic anti-tumour activity through mechanisms: Distinct from T cells and natural killer cells
10. Apoptosis by death factor
11. Death-inducing functions of ligands of the tumor necrosis factor family: A Sanhedrin verdict
12. Identification and characterization of a new member of the TNF family that induces apoptosis
13. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
14. Type 1 interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs
15. Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity
16. Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells
17. TRAIL: A molecule with multiple receptors and control mechanisms
18. The receptor for the cytotoxic ligand TRAIL
19. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
20. TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL
21. TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL
22. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
23. CD1d structure and regulation on human thymocytes, peripheral blood T cells, B cells and monocytes
24. Dendritic cells acquire antigen from apoptotic cells and induce class 1-restricted CTLs
25. Analysis of human V alpha 24+ CD4+ NKT cells activated by alpha-glycosylceramide-pulsed monocyte-derived dendritic cells
26. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity
27. Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes
28. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways
29. Perforin, Fas ligand, and tumor necrosis factor are the major cytotoxic molecules used by lymphokine-activated killer cells
30. Protein-antigen specific la-restricted cytolytic T cells: Analysis of frequency, target cell susceptibility, and mechanism of cytolysis
31. Perforin, Fas/Fas ligand, and TNF-alpha pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL
32. + natural killer T-cell cytotoxic activity: An important immune regulatory function
33. Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells
34. Dendritic cells derived in vitro from acute myelogenous leukemia cells stimulate autologous, antileukemic T-cell responses