Differential activation of TRAIL-R1 and-2 by soluble and membrane TRAIL allows selective surface antigen-directed activation of TRAIL-R2 by a soluble TRAIL derivative

Oncogene

Volumn 20, Issue 30, 2001, Pages 4101-4106

  Wajant, Harald ^a   Moosmayer, Dieter ^a,b   Wüest, Thomas ^a   Bartke, Till ^a   Gerlach, Elke ^a   Schönherr, Ulrike ^a   Peters, Nathalie ^a   Scheurich, Peter ^a   Pfizenmaier, Klaus ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

^b BAYER PHARMA AG   (Germany)

Author keywords

Antibody mediated; Apoptosis; Targeting; TNF ligand family; Tumor

Indexed keywords

DEATH RECEPTOR 4; DEATH RECEPTOR 5; MEMBRANE PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; GENE FUSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN IMMOBILIZATION; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION; SOLUBILITY;

ANIMALS; ANTIBODY SPECIFICITY; ANTIGENS, SURFACE; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CERCOPITHECUS AETHIOPS; COS CELLS; DRUG DESIGN; HELA CELLS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; JURKAT CELLS; KB CELLS; LIGANDS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; NEOPLASM PROTEINS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SOLUBILITY; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035811587     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1204558     Document Type: Article

References (15)