The role of the aspartate-arginine-tyrosine triad in the m1 muscarinic receptor: Mutations of aspartate 122 and tyrosine 124 decrease receptor expression but do not abolish signaling

Molecular Pharmacology

Volumn 51, Issue 2, 1997, Pages 234-241

  Lu, Zhi Liang ^a   Curtis, Carol A ^a   Jones, Philip G ^b   Pavia, Jose ^c   Hulme, Edward C ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b PFIZER INC   (United States)

^c UNIVERSITY OF MÁLAGA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ARGININE; ASPARTIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; METHYLSCOPOLAMINE; MUSCARINIC M1 RECEPTOR; RHODOPSIN; TRITIUM; TYROSINE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; DELETION MUTANT; GENE MUTATION; IMMUNOCYTOCHEMISTRY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

EID: 0031037632     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.51.2.234     Document Type: Article

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