Caffeine abolishes the mammalian G2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

Journal of Biological Chemistry

Volumn 275, Issue 14, 2000, Pages 10342-10348

  Zhou, Bin Bing S ^a   Chaturvedi, Priya ^a   Spring, Kevin ^b   Scott, Shaun P ^b   Johanson, Roy A ^a   Mishra, Rubin ^a   Mattern, Michael R ^a   Winkler, James D ^a   Khanna, Kum Kum ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CELL CYCLE PROTEIN; PHOSPHOTRANSFERASE; SERINE; THREONINE;

ARTICLE; ATAXIA; CELL CYCLE; CELL CYCLE G2 PHASE; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE MUTATION; HUMAN; HUMAN CELL; MITOSIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; TELANGIECTASIA;

ATAXIA TELANGIECTASIA; CAFFEINE; CDC25 PHOSPHATASE; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELL NUCLEUS; DNA DAMAGE; DNA-BINDING PROTEINS; G2 PHASE; GAMMA RAYS; HUMANS; KINETICS; MITOSIS; MUTAGENESIS, SITE-DIRECTED; PHOSPHOSERINE; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; TUMOR SUPPRESSOR PROTEINS;

ATAXIA; ATAXIA TELANGIECTASIA; MAMMALIA;

EID: 0034616329     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.14.10342     Document Type: Article

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