Pathway-specific tumor suppression: Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice

Cancer Cell

Volumn 1, Issue 4, 2002, Pages 355-368

  Philipp Staheli, Jeannette ^a   Kim, Kyung Hoon ^a   Payne, Shannon R ^a   Gurley, Kay E ^a   Liggitt, Denny ^b   Longton, Gary ^a   Kemp, Christopher J ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIMETHYLHYDRAZINE; APC PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; SMAD3 PROTEIN; BETA CATENIN; CATNB PROTEIN, MOUSE; CDKN1B PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYTOSKELETON PROTEIN; DNA BINDING PROTEIN; S PHASE KINASE ASSOCIATED PROTEIN; SMAD PROTEIN; TRANSACTIVATOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ADENOCARCINOMA; ADENOMA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; COLON CARCINOGENESIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; GASTROINTESTINAL CARCINOMA; GENE DELETION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR CELL; ANIMAL; C57BL MOUSE; CELL NUCLEUS; CHEMICALLY INDUCED DISORDER; COLORECTAL TUMOR; GASTROINTESTINAL TUMOR; GENETICS; HETEROZYGOSITY LOSS; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

1,2-DIMETHYLHYDRAZINE; ADENOCARCINOMA; ADENOMA; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; BETA CATENIN; CELL CYCLE PROTEINS; CELL NUCLEUS; COLORECTAL NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; GASTROINTESTINAL NEOPLASMS; GENES, TUMOR SUPPRESSOR; LOSS OF HETEROZYGOSITY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; S-PHASE KINASE-ASSOCIATED PROTEINS; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEINS;

EID: 0036559462     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(02)00054-5     Document Type: Article

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