Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay

Cancer Research

Volumn 56, Issue 24, 1996, Pages 5678-5683

  Tsunezuka, Yoshio ^a   Kinoh, Hiroaki ^a   Takino, Takahisa ^a   Watanabe, Yoh ^a   Okada, Yasunori ^a   Shinagawa, Akira ^b   Sato, Hiroshi ^a   Seiki, Motoharu ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b FUJI CHEMICAL INDUSTRIES LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; GELATINASE;

ARTICLE; ENZYME SPECIFICITY; EXTRACELLULAR MATRIX; FIBROSARCOMA; HUMAN; HUMAN CELL; LUNG METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTISENSE ELEMENTS (GENETICS); CELL ADHESION; FIBROSARCOMA; GELATINASES; GENE EXPRESSION; GENETIC VECTORS; HUMANS; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; MICE; NEOPLASM PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0029753004     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Alexander, C. M., and Werb, Z. Proteinases and extracellular matrix remodelling. Curr. Opin Cell Biol., 1: 974-982, 1989
2. Woessner, J. F. J Matrix metalloproteinases and their inhibitors in connective tissue remodelling. FASEB J., 5: 2145-2154, 1991.
3. Matrisian, L M The matrix-degrading metalloproteinases. BioEssays, 14. 455-463, 1992.
4. Stetler-Stevenson, W G., Aznavoorian, S., and Liotta, L. A. Tumor cell interactions with the extracellular matrix during invasion and metastasis Annu. Rev. Cell Biol., 9: 541-573, 1993.
5. Matrisian, L M. Metalloproteinases and their inhibitors in matrix remodelling Trends Genet., 6: 121-125, 1990.
6. Liotta, L A., Steeg, P. S., and Stetler-Stevenson, W. G. Cancer metastasis and angiogenesis an imbalance of positive and negative regulation Cell, 64 327-336, 1991
7. Tryggvason, K., Hoyhtya, M., and Pyke, C. Type IV collagenases in invasive tumors Breast Cancer Res Treat., 24: 209-218, 1993.
8. Sato, H , Takino, T., Okada, Y , Cao, J., Shinagawa, A , Yamamoto, E., and Seiki, M. A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature (Lond.), 370: 61-65, 1994.
9. Takino, T , Sato, H., Yamamoto, E., and Seiki, M Cloning of human gene potentially encoding a novel matrix metalloproteinase having a C-terminal transmembrane domain. Gene (Amst.), 115: 293-298, 1995
10. Will, H , and Hinzmann, B. cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment. Eur. J. Biochem., 231: 602-608, 1995
11. Takino, T., Sato, H., Shinagawa, A, and Seiki, M. Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. J. Biol Chem., 270: 23013-23020, 1995
12. Puente, X. S , Pendas, A M., Gloria, E L., Velasco, G., and Lopez-Otin, C. Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma Cancer Res., 56: 944-949, 1996.
13. Pei, D , and Weiss, S Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity. J. Biol Chem, 271: 9135-9140, 1996
14. Sato, H , Kinoshita, T , Takino, T., Nakayama, K., and Seiki, M. Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2. FEBS Lett , in press, 1996.
15. Pei, D., and Weiss, S J. Furin-dependent intracellular activation of the human stromelysin-3 zymogen. Nature (Lond), 375: 244-247, 1995
16. Atkinson, S J., Crabbe, T , Cowell, S., Ward, R. V., Butler, M. J , Sato, H., Seiki, M., Reynolds, J. J., and Murphy, G Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membranes. J. Biol. Chem., 270: 30479-30485, 1995.
17. Kinoshita, T., Sato, H., Takino, T., Itoh, M., Akizawa, T , and Seiki, M. Processing of a precursor of 72 kDa type IV collagenase/gelatinase A by a recombinant membrane type 1 matrix metalloproteinase. Cancer Res., 56. 2535-2538, 1996
18. Imai, K., Ohuchi, E., Aoki, T., Nomura, H., Fujii, Y., Sato, H , Seiki, M , and Okada, Y. Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinase 2. Cancer Res , 56: 2707-2710, 1996
19. Liotta, L. A. Tumor invasion and metastasis: role of the extracellular matrix, Cancer Res, 46: 1-7, 1986
20. Kleiner, D J , and Stetler-Stevenson, W. G Structural biochemistry and activation of matrix metalloproteinases. Curr. Opin Cell Biol., 5: 891-897, 1993.
21. Tokuraku, M, Sato, H, Murakami, S., Okada, Y., Watanabe, Y , and Seiki, M Activation of the precursor of gelatinase A/72 KDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis. Int. J. Cancer, 64: 355-359, 1995.
22. Nomura, H., Sato, H., Seiki, M., Mai, M., and Okada, Y. Expression of membrane-type matrix metalloproteinase in human gastric carcinomas Cancer Res., 55: 3263-3266, 1995
23. Yamamoto, M , Mohanam, S , Sawaya, R., Fuller, G N., Seiki, M., Sato, H , Gokaslan, Z. L., Liotta, L. A., Nicolson, G. L., and Rao, J S. Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro. Cancer Res., 56: 384-392, 1996
24. Polette, M., Nawrocki, B , Gilles, C , Sato, H., Seiki, M , Tournier, J., and Birembaut, P. MT-MMP expression and localization in human lung and breast cancers. Virchows Arch., 428: 29-35, 1996.
25. Gilles, C, Polette, M., Piette, J., Munaut, C., Thompson, E. W., Birembaut, P , and Foidart, J. M. High level of MT-MMP expression is associated with invasiveness of cervical cancer cells. Int J. Cancer, 65 209-213, 1996.
26. Okada, A., Bellocq, J. P , Rouyer, N., Chenard, M. P , Rio, M. C., Chambon, P., and Basset, P. Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc Natl. Acad Sci USA. 92: 2730-2734, 1995.
27. Marks, T. A. Characterization and responsiveness of the madison 109 lung carcinoma to various antitumor agents. Cancer Treat Rep., 61: 1459-1470, 1977
28. Tsuchiya, Y., Sato, H., Endo, Y., Okada, Y., Mai, M., Sasaki, T., and Seiki, M. Tissue inhibitor of metalloproteinase 1 is a negative regulator of the metastatic ability of a human gastric-cancer cell line, KKLS, in the chick embryo. Cancer Res , 53: 1397-1402, 1993.
29. Sato, H., Kita, M., and Seiki, M. v-Src activates the expression of 92 kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements A mechanism regulating gene expression independent of that by inflammatory cytokines. J Biol. Chem , 268: 23460-23468, 1993.
30. Akagi, T Å , Nyunoya, H , and Shimotohno, K Murine retroviral vectors expressing the taxi gene of human T-cell leukemia virus type 1 Gene (Amst.), 106: 255-259, 1991.
31. Wilhelm, S. M., Collier, I. E , Marmer, B. L, Eisen, A. Z., Grant, G A, and Goldberg, G. I. SV-40 transformed human lung fibroblasts secrets a 92 kDa type IV collagenase which is identical to that secreted by normal human macrophage. J. Biol. Chem, 264: 17213-17221, 1989.
32. Sato, H., Kida, Y., Mai, M., Endo, Y., Sasaki, T., Tanaka, J., and Seiki, M. Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells. Oncogene, 7: 77-83, 1992.
33. Hibbs, M. S., Hasty, K. A , Seyer, J M., Kang, A. H , and Marinardi, C. L. Å. Biochemical and immunological characterization of the secreted forms of human neutrophil gelatinase. J Biol. Chem., 260. 2493-2500, 1985
34. Southern, P , and Berg, P. Transformation of mammalian cells to antibiotic resistance with a bacterial gene under the control of the SV40 early region promoter. J Mol. Appl. Genet., 1: 327-341, 1982.
35. Fidler, I. J Quantitative analysis of distribution and fate of tumor emboli labeled with I-5-iodo-2′-deoxyuridine J. Natl. Cancer Inst , 45: 773-782, 1970
36. Polette, M, Clavel, C, Cockett, M., Girod de Bentzmann, S., Murphy, G., and Birembaut, P Detection and localization of mRNAs encoding matrix metalloproteinases and their tissue inhibitor in human breast pathology. Invasion Metastasis. 13: 31-37, 1993
37. Wolf, C., Rouyer, N , Lutz, Y., Adida, C., Loriot, M., Bellocq, J P , Chambon, P., and Basset, P Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression. Proc. Natl Acad. Sci USA, 90: 1843-1847, 1993.
38. Poulsom, R, Hanby, A. M., Pignatelli, M, Jeffery, R E., Longcroft, J M., Rogers, L., and Stamp, G. W. H. Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin J. Clin Pathol (Lond.), 46. 429-436, 1993.
39. Hoyhtya, M , Fridman, R , Komarek, D , Porter-Jordan, K., Stetler-Stevenson, W G., Liotta, L A , and Liang, C. M Immunohistochemical localization of matrix metalloproteinase 2 and its specific inhibitor TIMP-2 in neoplastic tissues with monoclonal antibodies. Int. J. Cancer, 56: 500-505, 1994.
40. r 72,000 type IV collagenase Cancer Res , 52 5845-5848, 1992.
41. Nakajima, M., Lotan, D , Baig, M. M., Carralero, R. M , Wood, W. R., Hendrix, M. J., and Lotan, R Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells. Cancer Res , 49 1698-1706, 1989.
42. Zucker, S., Moll, U. M , Lysik, R M., DiMassimo, E. I., Stetler, S. W., Liotta, L. A., and Schwedes, J. W. Extraction of type-IV collagenase/gelatinase from plasma membranes of human cancer cells. Int J. Cancer, 45: 1137-1142, 1990.
43. r 72,000 matrix metalloproteinase at cell surface invadopodia. Cancer Res., 53. 3159-3164, 1993.
44. Cao, J., Sato, H., Takino, T., and Seiki, M. The C-terminal region of membrane type matrix metalloproteinase is a function transmembrane domain required for progelatinase A activation J. Biol. Chem., 270 801-805, 1994.
45. Emmert-Buck, M , Emonard, H. P , Corcoran, M. L., Krutzsch, H. C., Foidart, J. M , and Stetler-Stevenson, W. Cell surface binding of TIMP-2 and pro-MMP-2/TIMP-2 complex. FEBS Lett., 364 28-32, 1995.
46. Strongin, A. Y., Collier, I., Bannikov, G., Marmer, B. L., Grant, G. A., and Goldberg, G I Mechanism of cell surface activation of 72 kDa type IV collagenase Isolation of the activated form of the membrane metalloprotease. J. Biol. Chem., 10: 5331-5338, 1995.
47. Brooks, P. C., Stromblad, S, Sanders, L. C., von Schalascha, T. L, Aimes, R. T., Stetler-Stevenson, W. G, Quigley, J. P., and Cheresh, D A. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αv/33. Cell, 85: 683-693, 1996.
48. Sato, H., Takino, T., Kinoshita, T., Imai, K, Okada, Y , Stetler-Stevenson, W , and Seiki, M. Cell surface binding and activation of gelatinase A induced by expression of membrane-type1-matrix metalloproteinase (MT1-MMP) FEBS Lett., 385: 238-240, 1996.