-
1
-
-
0022399581
-
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
-
Washington DC
-
Coussens, L., Yang-Feng, T. L., Liao, Y. C., Chen, E., Gray, A., McGrath, J., Seeburg, P. H., Libermann, T. A., Schlessinger, J., Francke, V., Levinson, A., and Ullrich, A. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science (Washington DC), 230: 1132-1139, 1985.
-
(1985)
Science
, vol.230
, pp. 1132-1139
-
-
Coussens, L.1
Yang-Feng, T.L.2
Liao, Y.C.3
Chen, E.4
Gray, A.5
McGrath, J.6
Seeburg, P.H.7
Libermann, T.A.8
Schlessinger, J.9
Francke, V.10
Levinson, A.11
Ullrich, A.12
-
2
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Washington DC
-
Slamon, D. J., Clark, G. M., Wong, S. G., Levin, W. J., Ullrich, A., and McGuire, W. L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (Washington DC). 235: 177-182, 1987.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
3
-
-
0026071364
-
The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells. SK-BR-3
-
Zabrecky, J. R., Lam, T., McKenzie, S. J., and Carney, W. The extracellular domain of p185/neu is released from the surface of human breast carcinoma cells. SK-BR-3. J. Biol. Chem., 266: 1716-1720, 1991.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 1716-1720
-
-
Zabrecky, J.R.1
Lam, T.2
McKenzie, S.J.3
Carney, W.4
-
4
-
-
0025829608
-
A soluble protein related to the HER-2 proto-oncogene product is released from human breast carcinoma cells
-
Lin, Y. L., and Clinton, G. M. A soluble protein related to the HER-2 proto-oncogene product is released from human breast carcinoma cells. Oncogene, 6: 639-643, 1991.
-
(1991)
Oncogene
, vol.6
, pp. 639-643
-
-
Lin, Y.L.1
Clinton, G.M.2
-
5
-
-
0027524245
-
The extracellular domain of the c-erbB-2 oncoprotein is released from tumor cells by proteolylic cleavage
-
Pupa, S. M., Menard, S., Morelli, D., Pozzi, B., De Palo, G., and Colnaghi, M. The extracellular domain of the c-erbB-2 oncoprotein is released from tumor cells by proteolylic cleavage. Oncogene, 8: 2917-2923, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 2917-2923
-
-
Pupa, S.M.1
Menard, S.2
Morelli, D.3
Pozzi, B.4
De Palo, G.5
Colnaghi, M.6
-
6
-
-
0031564215
-
Soluble HER-2/neu neutralizes biologic effects of anti-HER-2/neu antibody on breast cancer cells in vitro
-
Brodowicz, T., Wiltschke, C., Budinsky, A. C., Krainer, M., Steger, G. G., and Zielinski, C. C. Soluble HER-2/neu neutralizes biologic effects of anti-HER-2/neu antibody on breast cancer cells in vitro. Int. J. Cancer, 73: 875-879, 1997.
-
(1997)
Int. J. Cancer
, vol.73
, pp. 875-879
-
-
Brodowicz, T.1
Wiltschke, C.2
Budinsky, A.C.3
Krainer, M.4
Steger, G.G.5
Zielinski, C.C.6
-
7
-
-
0029991439
-
HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
-
HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J. Clin. Oncol. 14: 737-744, 1996.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelsohn, J.3
Baughman, S.4
Benz, C.C.5
Dantis, L.6
Sklarin, N.T.7
Seidman, A.D.8
Hudis, C.A.9
Moore, J.10
Rosen, P.P.11
Twaddell, T.12
Henderson, I.C.13
Norton, L.14
-
8
-
-
0031903646
-
HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment
-
HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J. Clin. Oncol., 16: 2659-2671, 1998.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 2659-2671
-
-
Pegram, M.D.1
Lipton, A.2
Hayes, D.F.3
Weber, B.L.4
Baselga, J.M.5
Tripathy, D.6
Baly, D.7
Baughman, S.A.8
Twaddell, T.9
Glaspy, J.A.10
Slamon, D.J.11
-
9
-
-
0029005754
-
Elevated serum c-erbB-2 antigen levels and decreased response to hormonal therapy of breast cancer
-
Leitzel, K., Teramoto, Y., Konrad, K., Chinchilli, V. M., Volas, G., Grossberg, H., Harvey, H., Demers, L., and Lipton, A. Elevated serum c-erbB-2 antigen levels and decreased response to hormonal therapy of breast cancer. J. Clin. Oncol., 13: 1129-1235, 1995.
-
(1995)
J. Clin. Oncol.
, vol.13
, pp. 1129-1235
-
-
Leitzel, K.1
Teramoto, Y.2
Konrad, K.3
Chinchilli, V.M.4
Volas, G.5
Grossberg, H.6
Harvey, H.7
Demers, L.8
Lipton, A.9
-
10
-
-
0030757466
-
Prediction of response to antiestrogen therapy in advanced breast cancer patients by pretreatment circulating levels of extracellular domain of the HER-2/c-neu protein
-
Yamauchi, H., O'Neill, A., Gelman, R. Carney, W., Tenney, D., Hosch, S., and Hayes, D. Prediction of response to antiestrogen therapy in advanced breast cancer patients by pretreatment circulating levels of extracellular domain of the HER-2/c-neu protein. J. Clin. Oncol., 15: 18-25, 1996.
-
(1996)
J. Clin. Oncol.
, vol.15
, pp. 18-25
-
-
Yamauchi, H.1
O'Neill, A.2
Gelman, R.3
Carney, W.4
Tenney, D.5
Hosch, S.6
Hayes, D.7
-
11
-
-
0000908721
-
The role of ERBB2 extracellular domain in predicting response to chemotherapy in breast cancer patients
-
Harris, L. N., Trock, B., Berris, M., Esteva-Lorenzo, F., and Paik, S. The role of ERBB2 extracellular domain in predicting response to chemotherapy in breast cancer patients. Proc. Am. Soc. Clin. Oncol., 15: A96, 1996.
-
(1996)
Proc. Am. Soc. Clin. Oncol.
, vol.15
-
-
Harris, L.N.1
Trock, B.2
Berris, M.3
Esteva-Lorenzo, F.4
Paik, S.5
-
12
-
-
0023196582
-
erbB-2 is a potent oncogene when overexpressed in NIH/3t3 cells
-
Washington, DC
-
Di Fiore, P. P., Pierce, J. H., Kraus, M. H., Segatto, O., King, C. R., and Aaronson, S. A. erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science (Washington, DC), 237: 178-182, 1987.
-
(1987)
Science
, vol.237
, pp. 178-182
-
-
Di Fiore, P.P.1
Pierce, J.H.2
Kraus, M.H.3
Segatto, O.4
King, C.R.5
Aaronson, S.A.6
-
13
-
-
0023733226
-
Different structural alterations up-regulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene
-
Segatto, O., King, C. R., Pierce, J. H., Di Fiore, P. P., and Aaronson, S. A. Different structural alterations up-regulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene. Mol. Cell. Biol., 8: 5570-5574, 1988.
-
(1988)
Mol. Cell. Biol.
, vol.8
, pp. 5570-5574
-
-
Segatto, O.1
King, C.R.2
Pierce, J.H.3
Di Fiore, P.P.4
Aaronson, S.A.5
-
14
-
-
0031032891
-
Membrane protein secretases
-
Hooper, N. M., Karran, E. H., and Turner, A. J. Membrane protein secretases. Biochem. J., 321: 265-279, 1997.
-
(1997)
Biochem. J.
, vol.321
, pp. 265-279
-
-
Hooper, N.M.1
Karran, E.H.2
Turner, A.J.3
-
15
-
-
0030834283
-
Metalloprotease-disintegrins: Links to cell adhesion and cleavage of TNF-α and notch
-
Blobel, C. P. Metalloprotease-disintegrins: links to cell adhesion and cleavage of TNF-α and Notch. Cell. 90: 589-592, 1998
-
(1998)
Cell
, vol.90
, pp. 589-592
-
-
Blobel, C.P.1
-
16
-
-
0032515018
-
An essential role for ectodomains shedding in mammalian development
-
Washington, DC
-
Peschon, J., Slack, J., Reddy, P., Stocking, K., Sunnarborg, S., Lee, D., Rusell, W., Castner, R., Johnson, R., Fitzner, J., Boyce, N., Nelson, C., Kozlosky, M., Wolfson, M., Rauch, C., Cerretti, D., Paxton, R., March, C., and Black, R. An essential role for ectodomains shedding in mammalian development. Science (Washington, DC), 282: 1281-1284, 1998.
-
(1998)
Science
, vol.282
, pp. 1281-1284
-
-
Peschon, J.1
Slack, J.2
Reddy, P.3
Stocking, K.4
Sunnarborg, S.5
Lee, D.6
Rusell, W.7
Castner, R.8
Johnson, R.9
Fitzner, J.10
Boyce, N.11
Nelson, C.12
Kozlosky, M.13
Wolfson, M.14
Rauch, C.15
Cerretti, D.16
Paxton, R.17
March, C.18
Black, R.19
-
17
-
-
0027468645
-
A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells
-
Scott, G. K., Robles, R., Park, J. W., Montgomery, P. A., Daniel, J., Holmes, W. E., Lee, J., Keller, G. A., Li, W., Fendly, B. M., Wood, W. I., Shepard, M., and Benz, C. C. A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells. Mol. Cell. Biol., 13: 2247-2257. 1993.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 2247-2257
-
-
Scott, G.K.1
Robles, R.2
Park, J.W.3
Montgomery, P.A.4
Daniel, J.5
Holmes, W.E.6
Lee, J.7
Keller, G.A.8
Li, W.9
Fendly, B.M.10
Wood, W.I.11
Shepard, M.12
Benz, C.C.13
-
18
-
-
0031848158
-
Phase I study of intraperitoneal metalloproteinase inhibitor BB94 in patients with malignant ascites
-
Beattie, G. J., and Smyth, J. F. Phase I study of intraperitoneal metalloproteinase inhibitor BB94 in patients with malignant ascites. Clin. Cancer Res., 4: 1899-1902, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 1899-1902
-
-
Beattie, G.J.1
Smyth, J.F.2
-
19
-
-
1842375639
-
Role of the juxtamembrane domains of the transforming growth factor-α precursor and the β-amyloid precursor protein in regulated ectodomain shedding
-
Arribas, J., López-Casillas, F., and Massagué, J. Role of the juxtamembrane domains of the transforming growth factor-α precursor and the β-amyloid precursor protein in regulated ectodomain shedding. J. Biol. Chem., 272: 17160-17165, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17160-17165
-
-
Arribas, J.1
López-Casillas, F.2
Massagué, J.3
-
20
-
-
15844406752
-
Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors
-
Arribas, J., Coodly, L., Vollmer, P., Kishimoto, T. K., Rose-John, S., and Massagué, J. Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors. J. Biol. Chem., 271: 11376-11382, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 11376-11382
-
-
Arribas, J.1
Coodly, L.2
Vollmer, P.3
Kishimoto, T.K.4
Rose-John, S.5
Massagué, J.6
-
21
-
-
0030583282
-
Relaxed specificity of matrix metalloproteinases (MMPS) and TIMP insensitivity of tumor necrosis factor-α (TNF-α) production suggest the major TNF-α converting enzyme is not an MMP
-
Black, R. A., Durie, F. H., Otten-Evans, C., Miller, R., Slack, J. L., Lynch, D. H., Castner, B., Mohler, K. M., Gerhart, M., Johnson, R. S., Itoh, Y., Okada, Y., and Nagase, H. Relaxed specificity of matrix metalloproteinases (MMPS) and TIMP insensitivity of tumor necrosis factor-α (TNF-α) production suggest the major TNF-α converting enzyme is not an MMP. Biochem. Biophys. Res. Commun., 225: 400-405, 1996.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 400-405
-
-
Black, R.A.1
Durie, F.H.2
Otten-Evans, C.3
Miller, R.4
Slack, J.L.5
Lynch, D.H.6
Castner, B.7
Mohler, K.M.8
Gerhart, M.9
Johnson, R.S.10
Itoh, Y.11
Okada, Y.12
Nagase, H.13
-
22
-
-
0032508675
-
TNK-α converting enzyme (TACE) is inhibited by TIMP-3
-
Amour, A., Slocombe, P. M., Webster, A., Butler, M., Knight, C. G., Smith, B. J., Stephens, P. E., Shelley, C., Hutton, M., Knauper, V., Docherty, A. J., and Murphy, G. TNK-α converting enzyme (TACE) is inhibited by TIMP-3. FEBS Lett., 435: 39-44, 1998.
-
(1998)
FEBS Lett.
, vol.435
, pp. 39-44
-
-
Amour, A.1
Slocombe, P.M.2
Webster, A.3
Butler, M.4
Knight, C.G.5
Smith, B.J.6
Stephens, P.E.7
Shelley, C.8
Hutton, M.9
Knauper, V.10
Docherty, A.J.11
Murphy, G.12
-
23
-
-
0029764504
-
Selective cleavage of the heregulin receptor ErbB-4 by protein kinase C activation
-
Vecchi, M., Baulida, J., and Carpenter, G. Selective cleavage of the heregulin receptor ErbB-4 by protein kinase C activation. J. Biol. Chem., 271: 18989-18995. 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 18989-18995
-
-
Vecchi, M.1
Baulida, J.2
Carpenter, G.3
-
24
-
-
0029853095
-
Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syrdecan-1
-
Reiland, J., Ott, V. L., Lebakken, C. S., Yeaman, C., McCarthy, J., and Rapraeger, A. C. Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syrdecan-1. Biochem. J., 319: 39-47, 1996.
-
(1996)
Biochem. J.
, vol.319
, pp. 39-47
-
-
Reiland, J.1
Ott, V.L.2
Lebakken, C.S.3
Yeaman, C.4
McCarthy, J.5
Rapraeger, A.C.6
-
25
-
-
0028935040
-
Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor
-
Slack, B. E., Breu, J., Petryniak, M. A., Srivastava, K., and Wurtman, R. J. Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor. J. Biol. Chem., 270, 8337-8344, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 8337-8344
-
-
Slack, B.E.1
Breu, J.2
Petryniak, M.A.3
Srivastava, K.4
Wurtman, R.J.5
-
26
-
-
0033525037
-
Metalloprotease-disintegrin MDC9: Intracellular maturation and catalytic activity
-
Roghani, M., Becherer, J. D., Moss, M. L., Atherton, R. E., Erdjument-Bromage, H., Arribas, J., Blackburn, R. K., Weskamp, G., Tempst, P., and Blobel, C. P. Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. J. Biol. Chem., 274: 3531-3540, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 3531-3540
-
-
Roghani, M.1
Becherer, J.D.2
Moss, M.L.3
Atherton, R.E.4
Erdjument-Bromage, H.5
Arribas, J.6
Blackburn, R.K.7
Weskamp, G.8
Tempst, P.9
Blobel, C.P.10
-
27
-
-
0030717692
-
Tissue inhibitors of metalloproteinases: Structure, regulation and biological functions
-
Gomez, D. E., Alonso, D. F., Yoshiji, H., and Thorgeirsson, U. P. Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur. J. Cell. Biol., 74: 111-122, 1997.
-
(1997)
Eur. J. Cell. Biol.
, vol.74
, pp. 111-122
-
-
Gomez, D.E.1
Alonso, D.F.2
Yoshiji, H.3
Thorgeirsson, U.P.4
-
28
-
-
0031802915
-
Human myeloma cells shed the interleukin-6 receptor: Inhibition by tissue inhibitor of metalloproteinase-3 and a hydroxamate-based metalloproteinase inhibitor
-
Hargreaves, P. G., Wang, F., Antcliff, J., Murphy, G., Lawry, J., Russell, R. G., and Crocher, P. I. Human myeloma cells shed the interleukin-6 receptor: inhibition by tissue inhibitor of metalloproteinase-3 and a hydroxamate-based metalloproteinase inhibitor. Br. J. Haematol., 101: 694-702, 1998.
-
(1998)
Br. J. Haematol.
, vol.101
, pp. 694-702
-
-
Hargreaves, P.G.1
Wang, F.2
Antcliff, J.3
Murphy, G.4
Lawry, J.5
Russell, R.G.6
Crocher, P.I.7
-
29
-
-
0032170034
-
Synthetic matrix metalloproteinase inhibitors and tissue inhibitor of metalloproteinase (TIMP)-2. But not TIMP-1. Inhibit shedding of tumor necrosis factor-α receptors in a human colon adenocarcinoma (Colo 205) cell line
-
Lombard, M. A., Wallace, T. L., Kubicek, M. F., Petzold, G. L., Mitchell, M. A., Hendges, S. K., and Wilks, J. W. Synthetic matrix metalloproteinase inhibitors and tissue inhibitor of metalloproteinase (TIMP)-2. but not TIMP-1. inhibit shedding of tumor necrosis factor-α receptors in a human colon adenocarcinoma (Colo 205) cell line. Cancer Res., 58: 4001-4007, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 4001-4007
-
-
Lombard, M.A.1
Wallace, T.L.2
Kubicek, M.F.3
Petzold, G.L.4
Mitchell, M.A.5
Hendges, S.K.6
Wilks, J.W.7
-
30
-
-
17544382630
-
Metalloproteinase-mediated regulation of L-selectin levels on leucocytes
-
Preece, G., Murphy, G., and Ager, A. Metalloproteinase-mediated regulation of L-selectin levels on leucocytes. J. Biol. Chem., 271: 11634-11640, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 11634-11640
-
-
Preece, G.1
Murphy, G.2
Ager, A.3
|