Cellular Activation of MMP-2 (Gelatinase A) by MT2-MMP Occurs via a TIMP-2-independent Pathway

Journal of Biological Chemistry

Volumn 276, Issue 50, 2001, Pages 47402-47410

  Morrison, Charlotte J ^a   Butler, Georgina S ^a   Bigg, Heather F ^a   Roberts, Clive R ^a   Soloway, Paul D ^b   Overall, Christopher M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; TISSUE;

CELLULAR ACTIVATION;

BIOLOGICAL MEMBRANES;

CONCANAVALIN A; GELATINASE A; HEMOPEXIN; HEMOPEXIN C; MATRIX METALLOPROTEINASE 14; MEMBRANE TYPE 2 MATRIX METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 4; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; MEMBRANE TYPE MATRIX METALLOPROTEINASE; MEMBRANE-TYPE MATRIX METALLOPROTEINASE; MESSENGER RNA; METALLOPROTEINASE; RECOMBINANT PROTEIN;

ADDITION REACTION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ACTIVITY; CELL SURFACE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVATION; ENZYME INHIBITION; INHIBITION KINETICS; MEMBRANE BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; TISSUE SPECIFICITY; ANIMAL; CELL CULTURE; CELL LINE; CHO CELL; DNA VECTOR; DOSE RESPONSE; GENE DELETION; GENETIC TRANSFECTION; HAMSTER; HUMAN; IMMUNOHISTOCHEMISTRY; KINETICS; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; TIME; TRANSGENIC MOUSE;

ANIMALIA;

ANIMAL; CELL LINE; CELLS, CULTURED; CHO CELLS; CONCANAVALIN A; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GELATINASE A; GENE DELETION; GENETIC VECTORS; HAMSTERS; HEMOPEXIN; HUMAN; IMMUNOHISTOCHEMISTRY; KINETICS; METALLOENDOPEPTIDASES; MICE; MICE, TRANSGENIC; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; TISSUE INHIBITOR-OF METALLOPROTEINASE-2; TRANSFECTION;

EID: 0035861560     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108643200     Document Type: Article

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