Tumor targeting with a selective gelatinase inhibitor

Nature Biotechnology

Volumn 17, Issue 8, 1999, Pages 768-774

  Koivunen, Erkki ^b   Arap, Wadih ^a   Valtanen, Heli ^b   Rainisalo, Aija ^b   Medina, Oula Penate ^b   Heikkilä, Pia ^b   Kantor, Carmela ^b   Gahmberg, Carl G ^b   Salo, Tuula ^b   Konttinen, Yrjö T ^b   Sorsa, Timo ^b   Ruoslahti, Erkki ^a   Pasqualini, Renata ^a  

^a BURNHAM INSTITUTE   (United States)

^b NONE

Author keywords

Angiogenesis; Cancer therapy; Matrix metalloproteinase; Phage display; Tumor targeting

Indexed keywords

CYCLOPEPTIDE; GELATINASE A; GELATINASE B; GELATINASE INHIBITOR; MATRIX METALLOPROTEINASE; PEPTIDE LIBRARY; SYNTHETIC PEPTIDE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CELL MIGRATION; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; METASTASIS; MOUSE; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TUMOR CELL DESTRUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; COLLAGENASES; DNA PRIMERS; ENZYME INHIBITORS; FEMALE; GELATINASES; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR SEQUENCE DATA; NEOPLASM TRANSPLANTATION; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDE LIBRARY; PEPTIDES, CYCLIC;

ANIMALIA;

EID: 0032842567     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/11703     Document Type: Article

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