메뉴 건너뛰기




Volumn 161, Issue 4, 1998, Pages 1664-1670

Low dose TGF-β attenuates IL-12 responsiveness in murine Th cells

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR; MESSENGER RNA; NITRIC OXIDE; RECOMBINANT INTERLEUKIN 4; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA;

EID: 0032529414     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (104)

References (61)
  • 1
    • 0029071483 scopus 로고
    • Developmental commitment to the Th2 lineage by extinction of IL-12 signaling
    • Szabo, S. J., N. G. Jacobson, A. S. Dighe, U. Gubler, and K. M. Murphy. 1995. Developmental commitment to the Th2 lineage by extinction of IL-12 signaling. Immunity 2:665.
    • (1995) Immunity , vol.2 , pp. 665
    • Szabo, S.J.1    Jacobson, N.G.2    Dighe, A.S.3    Gubler, U.4    Murphy, K.M.5
  • 2
    • 0030042868 scopus 로고    scopus 로고
    • Genetic susceptibility to Leishmania: IL-12 responsiveness in determining TH1 cell development
    • Güler, M. L., J. D. Gorham, C. Hsieh, A. J. Mackey, R. G. Steen, W. F. Dietrich, and K. M. Murphy. 1996. Genetic susceptibility to Leishmania: IL-12 responsiveness in determining TH1 cell development. Science 271:984.
    • (1996) Science , vol.271 , pp. 984
    • Güler, M.L.1    Gorham, J.D.2    Hsieh, C.3    Mackey, A.J.4    Steen, R.G.5    Dietrich, W.F.6    Murphy, K.M.7
  • 4
    • 0028892869 scopus 로고
    • Cloning and characterization of a mouse IL-12 receptor-β component
    • Chua, A. O., V. L. Wilkinson, D. H. Presky, and U. Gubler. 1995. Cloning and characterization of a mouse IL-12 receptor-β component. J. Immunol. 155:4286.
    • (1995) J. Immunol. , vol.155 , pp. 4286
    • Chua, A.O.1    Wilkinson, V.L.2    Presky, D.H.3    Gubler, U.4
  • 5
    • 8044250881 scopus 로고    scopus 로고
    • Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells
    • Szabo, S. J., A. S. Dighe, U. Gubler, and K. M. Murphy. 1997. Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 185:817.
    • (1997) J. Exp. Med. , vol.185 , pp. 817
    • Szabo, S.J.1    Dighe, A.S.2    Gubler, U.3    Murphy, K.M.4
  • 7
    • 0031571196 scopus 로고    scopus 로고
    • T cell genetic background determines maintenance of IL-12 signaling: Effects on BALB/c and B10. D2 T helper cell type 1 phenotype development
    • Güler, M. L., N. G. Jacobson, U. Gubler, and K. M. Murphy. 1997. T cell genetic background determines maintenance of IL-12 signaling: effects on BALB/c and B10. D2 T helper cell type 1 phenotype development. J. Immunol. 159:1767.
    • (1997) J. Immunol. , vol.159 , pp. 1767
    • Güler, M.L.1    Jacobson, N.G.2    Gubler, U.3    Murphy, K.M.4
  • 8
    • 0025820205 scopus 로고
    • Reconstitution of Leishmania immunity in severe combined immunodeficient mice using Th1- And Th2-like cell lines
    • Holaday, B. J., M. D. Sadick, Z.-E. Wang, S. L. Reiner, F. P. Heinzel, T. G. Parslow, and R. M. Locksley. 1991. Reconstitution of Leishmania immunity in severe combined immunodeficient mice using Th1-and Th2-like cell lines. J. Immunol. 147:1653.
    • (1991) J. Immunol. , vol.147 , pp. 1653
    • Holaday, B.J.1    Sadick, M.D.2    Wang, Z.-E.3    Reiner, S.L.4    Heinzel, F.P.5    Parslow, T.G.6    Locksley, R.M.7
  • 9
    • 0024540908 scopus 로고
    • Reciprocal expression of IFN γ or interleukin 4 during the resolution or progression of murine leishmaniasis: Evidence for expansion of distinct helper T cell subsets
    • Heinzel, F. P., M. D. Sadick, B. J. Holaday, R. L. Coffman, and R. M. Locksley. 1989. Reciprocal expression of IFN γ or interleukin 4 during the resolution or progression of murine leishmaniasis: evidence for expansion of distinct helper T cell subsets. J. Exp. Med. 169:59.
    • (1989) J. Exp. Med. , vol.169 , pp. 59
    • Heinzel, F.P.1    Sadick, M.D.2    Holaday, B.J.3    Coffman, R.L.4    Locksley, R.M.5
  • 10
    • 0028933795 scopus 로고
    • The regulation of immunity to Leishmania major
    • Reiner, S. L. and R. M. Locksley. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:151.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 151
    • Reiner, S.L.1    Locksley, R.M.2
  • 14
    • 0031114125 scopus 로고    scopus 로고
    • Early production of IL-4 in susceptible mice infected with Leishmania major rapidly induces IL-12 unresponsiveness
    • Launois, P., K. G. Swihart, G. Milon, and J. A. Louis. 1997. Early production of IL-4 in susceptible mice infected with Leishmania major rapidly induces IL-12 unresponsiveness. J. Immunol. 158:3317.
    • (1997) J. Immunol. , vol.158 , pp. 3317
    • Launois, P.1    Swihart, K.G.2    Milon, G.3    Louis, J.A.4
  • 15
    • 0023726231 scopus 로고
    • Deactivation of macrophages by TGF-β
    • Tsunawaki, S., M. Sporn, A. Ding, and C. Nathan. 1988. Deactivation of macrophages by TGF-β. Nature 334:260.
    • (1988) Nature , vol.334 , pp. 260
    • Tsunawaki, S.1    Sporn, M.2    Ding, A.3    Nathan, C.4
  • 17
    • 0023583780 scopus 로고
    • Inhibition of cytotoxic T cell development by transforming growth factor β and reversal by recombinant tumor necrosis factor α
    • Ranges, G. E., I. S. Figari, T. Espevik, and M. A. Palladino, Jr. 1987. Inhibition of cytotoxic T cell development by transforming growth factor β and reversal by recombinant tumor necrosis factor α. J. Exp. Med. 166:991.
    • (1987) J. Exp. Med. , vol.166 , pp. 991
    • Ranges, G.E.1    Figari, I.S.2    Espevik, T.3    Palladino Jr., M.A.4
  • 18
    • 0023746462 scopus 로고
    • Transforming growth factor-β1 modulates the expression of class II histocompatibility antigens on human cells
    • Czarniecki, C. W., H. H. Chiu, G. H. Wong, S. M. McCabe, and M. A. Palladino. 1988. Transforming growth factor-β1 modulates the expression of class II histocompatibility antigens on human cells. J. Immunol. 140:4217.
    • (1988) J. Immunol. , vol.140 , pp. 4217
    • Czarniecki, C.W.1    Chiu, H.H.2    Wong, G.H.3    McCabe, S.M.4    Palladino, M.A.5
  • 19
    • 0031093495 scopus 로고    scopus 로고
    • TGF-β suppresses IFN-γ induction of class II MHC gene expression by inhibiting class II transactivator messenger RNA expression
    • Lee, Y. J., Y. Han, H. T. Lu, V. Nguyen, H. Qin, P. H. Howe, B. A. Hocevar, J. M. Boss, R. M. Ransohoff, and E. N. Benveniste. 1997. TGF-β suppresses IFN-γ induction of class II MHC gene expression by inhibiting class II transactivator messenger RNA expression. J. Immunol. 158:2065.
    • (1997) J. Immunol. , vol.158 , pp. 2065
    • Lee, Y.J.1    Han, Y.2    Lu, H.T.3    Nguyen, V.4    Qin, H.5    Howe, P.H.6    Hocevar, B.A.7    Boss, J.M.8    Ransohoff, R.M.9    Benveniste, E.N.10
  • 21
    • 0025114866 scopus 로고
    • TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop
    • Battegay, E. J., E. W. Raines, R. A. Seifert, D. F. Bowen-Pope, and R. Ross. 1990. TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell 63:515.
    • (1990) Cell , vol.63 , pp. 515
    • Battegay, E.J.1    Raines, E.W.2    Seifert, R.A.3    Bowen-Pope, D.F.4    Ross, R.5
  • 22
    • 0023664056 scopus 로고
    • Transforming growth factor β is a bifunctional regulator of replication and collagen synthesis in osteoblast-enriched cell cultures from fetal rat bone
    • Centrella, M., T. L. McCarthy, and E. Canalis. 1987. Transforming growth factor β is a bifunctional regulator of replication and collagen synthesis in osteoblast-enriched cell cultures from fetal rat bone. J. Biol. Chem. 262:2869.
    • (1987) J. Biol. Chem. , vol.262 , pp. 2869
    • Centrella, M.1    McCarthy, T.L.2    Canalis, E.3
  • 24
    • 0027724228 scopus 로고
    • Transforming growth factor-β1 knockout mice: A mutation in one cytokine gene causes a dramatic inflammatory disease
    • Kulkarni, A. B., and S. Karlsson. 1993. Transforming growth factor-β1 knockout mice: a mutation in one cytokine gene causes a dramatic inflammatory disease. Am. J. Pathol. 143:3.
    • (1993) Am. J. Pathol. , vol.143 , pp. 3
    • Kulkarni, A.B.1    Karlsson, S.2
  • 26
    • 0029952226 scopus 로고    scopus 로고
    • Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor β1 null mouse
    • Vodovotz, Y., A. G. Geiser, L. Chesler, J. J. Letterio, A. Campbell, M. S. Lucia, M. B. Sporn, and A. B. Roberts. 1996. Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor β1 null mouse. J. Exp. Med. 183:2337.
    • (1996) J. Exp. Med. , vol.183 , pp. 2337
    • Vodovotz, Y.1    Geiser, A.G.2    Chesler, L.3    Letterio, J.J.4    Campbell, A.5    Lucia, M.S.6    Sporn, M.B.7    Roberts, A.B.8
  • 28
    • 0025179010 scopus 로고
    • The autocrine production of TGF-β1 during lymphocyte activation: A study with a monoclonal antibody-based ELISA
    • Lucas, C., L. N. Bald, B. M. Fendly, M. Mora-Worms, I. S. Figari, E. J. Patzer, and M. A. Palladino. 1990. The autocrine production of TGF-β1 during lymphocyte activation: a study with a monoclonal antibody-based ELISA. J. Immunol. 145:1415.
    • (1990) J. Immunol. , vol.145 , pp. 1415
    • Lucas, C.1    Bald, L.N.2    Fendly, B.M.3    Mora-Worms, M.4    Figari, I.S.5    Patzer, E.J.6    Palladino, M.A.7
  • 29
    • 0031567889 scopus 로고    scopus 로고
    • Identification of IL-4 promoter elements conferring Th2-restricted expression during T helper cell subset development
    • Wenner, C. A., S. J. Szabo, and K. M. Murphy. 1997. Identification of IL-4 promoter elements conferring Th2-restricted expression during T helper cell subset development. J. Immunol. 158:765.
    • (1997) J. Immunol. , vol.158 , pp. 765
    • Wenner, C.A.1    Szabo, S.J.2    Murphy, K.M.3
  • 31
    • 0026648380 scopus 로고
    • Differential regulation of T helper phenotype development by interleukins 4 and 10 in an αβ T-cell-receptor transgenic system
    • Hsieh C. S., A. B. Heimberger, J. S. Gold, A. O'Garra, and K. M. Murphy. 1992. Differential regulation of T helper phenotype development by interleukins 4 and 10 in an αβ T-cell-receptor transgenic system. Proc. Natl. Acad. Sci. USA 89:6065.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6065
    • Hsieh, C.S.1    Heimberger, A.B.2    Gold, J.S.3    O'Garra, A.4    Murphy, K.M.5
  • 34
    • 0028328817 scopus 로고
    • An assay for transforming growth factor-β using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct
    • Abe, M., J. G. Harpel, C. N. Metz, I. Nunes, D. J. Loskutoff, and D. B. Rifkin. 1994. An assay for transforming growth factor-β using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal. Biochem. 216:276.
    • (1994) Anal. Biochem. , vol.216 , pp. 276
    • Abe, M.1    Harpel, J.G.2    Metz, C.N.3    Nunes, I.4    Loskutoff, D.J.5    Rifkin, D.B.6
  • 35
    • 0026334362 scopus 로고
    • Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to TGF-β
    • Keeton, M. R., S. A. Curriden, A. J. van Zonneveld, and D. J. Loskutoff. 1991. Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to TGF-β. J. Biol. Chem. 266:23048.
    • (1991) J. Biol. Chem. , vol.266 , pp. 23048
    • Keeton, M.R.1    Curriden, S.A.2    Van Zonneveld, A.J.3    Loskutoff, D.J.4
  • 36
    • 0023193194 scopus 로고
    • Latent TGF-β in serum: A specific complex with α2-macroglobulin
    • O'Connor-McCourt, M. D., and L. M. Wakefield. 1987. Latent TGF-β in serum: a specific complex with α2-macroglobulin. J. Biol. Chem. 262:14090.
    • (1987) J. Biol. Chem. , vol.262 , pp. 14090
    • O'Connor-McCourt, M.D.1    Wakefield, L.M.2
  • 38
    • 0025609915 scopus 로고
    • Tumor necrosis factor-α synergizes with IFN-γ in mediating killing of Leishmania major through the induction of nitric oxide
    • Liew, F. Y., Y. Li, and S. Millott. 1990. Tumor necrosis factor-α synergizes with IFN-γ in mediating killing of Leishmania major through the induction of nitric oxide. J. Immunol. 145:4306.
    • (1990) J. Immunol. , vol.145 , pp. 4306
    • Liew, F.Y.1    Li, Y.2    Millott, S.3
  • 39
    • 0025942326 scopus 로고
    • Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation: Role of IFN-gamma in the induction of the nitric oxide-synthesizing pathway
    • Albina, J. E., J. A. Abate, and W. L. Henry, Jr. 1991. Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation: role of IFN-gamma in the induction of the nitric oxide-synthesizing pathway. J. Immunol. 147:144.
    • (1991) J. Immunol. , vol.147 , pp. 144
    • Albina, J.E.1    Abate, J.A.2    Henry Jr., W.L.3
  • 41
    • 0028906593 scopus 로고
    • T cell genetic background determines default T helper phenotype development in vitro
    • Hsieh, C. S., S. E. Macatonia, A. O'Garra, and K. M. Murphy. 1995. T cell genetic background determines default T helper phenotype development in vitro. J. Exp. Med. 181:713.
    • (1995) J. Exp. Med. , vol.181 , pp. 713
    • Hsieh, C.S.1    Macatonia, S.E.2    O'Garra, A.3    Murphy, K.M.4
  • 42
    • 0030923103 scopus 로고    scopus 로고
    • Resistance to Leishmania major is linked to the H2 region on chromosome 17 and to chromosome 9
    • Roberts, L. J., T. M. Baldwin, J. M. Curtis, E. Handman, and S. J. Foote. 1997. Resistance to Leishmania major is linked to the H2 region on chromosome 17 and to chromosome 9. J. Exp. Med. 185:1705.
    • (1997) J. Exp. Med. , vol.185 , pp. 1705
    • Roberts, L.J.1    Baldwin, T.M.2    Curtis, J.M.3    Handman, E.4    Foote, S.J.5
  • 43
    • 0030612781 scopus 로고    scopus 로고
    • Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice
    • Beebe, A. M., S. Mauze, N. J. Schork, and R. L. Coffman. 1997. Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice. Immunity 6:551.
    • (1997) Immunity , vol.6 , pp. 551
    • Beebe, A.M.1    Mauze, S.2    Schork, N.J.3    Coffman, R.L.4
  • 44
    • 0025951644 scopus 로고
    • Transforming growth factor-β and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype
    • Swain, S. L., G. Huston, S. Tonkonogy, and A. D. Weinberg. 1991. Transforming growth factor-β and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphokine secretion pattern and cell surface phenotype. J. Immunol. 147:2991.
    • (1991) J. Immunol. , vol.147 , pp. 2991
    • Swain, S.L.1    Huston, G.2    Tonkonogy, S.3    Weinberg, A.D.4
  • 45
    • 0027272821 scopus 로고
    • Role of transforming growth factor-β in the preferential induction of T helper cells of type 1 by staphylococcal enterotoxin B
    • Nagelkerken, L., K. J. Gollob, M. Tielemans, and R. L. Coffman. 1993. Role of transforming growth factor-β in the preferential induction of T helper cells of type 1 by staphylococcal enterotoxin B. Eur. J. Immunol. 23:2306.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2306
    • Nagelkerken, L.1    Gollob, K.J.2    Tielemans, M.3    Coffman, R.L.4
  • 47
    • 0027959893 scopus 로고
    • Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype
    • Sad, S., and T. R. Mosmann. 1994. Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. J. Immunol. 153:3514.
    • (1994) J. Immunol. , vol.153 , pp. 3514
    • Sad, S.1    Mosmann, T.R.2
  • 49
    • 0027216817 scopus 로고
    • + T cells by transforming growth factor-β1
    • + T cells by transforming growth factor-β1. J. Immunol. 151:668.
    • (1993) J. Immunol. , vol.151 , pp. 668
    • Lee, H.M.1    Rich, S.2
  • 50
    • 0030775109 scopus 로고    scopus 로고
    • From receptor to nucleus: The Smad pathway
    • Baker, J. C., and R. M. Harland. 1997. From receptor to nucleus: the Smad pathway. Curr. Opin. Genet. Dev. 7:467.
    • (1997) Curr. Opin. Genet. Dev. , vol.7 , pp. 467
    • Baker, J.C.1    Harland, R.M.2
  • 55
    • 0029995799 scopus 로고    scopus 로고
    • Experimental granulomatous colitis in mice is abrogated by induction of TGF-β-mediated oral tolerance
    • Neurath, M. F., I. Fuss, B. L. Kelsall, D. H. Presky, W. Waegell, and W. Strober. 1996. Experimental granulomatous colitis in mice is abrogated by induction of TGF-β-mediated oral tolerance. J. Exp. Med. 183:2605.
    • (1996) J. Exp. Med. , vol.183 , pp. 2605
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Presky, D.H.4    Waegell, W.5    Strober, W.6
  • 57
    • 0029315079 scopus 로고
    • Cytokine-producing cells in experimental autoimmune encephalomyelitis and multiple sclerosis
    • Olsson, T. 1995. Cytokine-producing cells in experimental autoimmune encephalomyelitis and multiple sclerosis. Neurology 45:S11.
    • (1995) Neurology , vol.45
    • Olsson, T.1
  • 58
    • 0027209457 scopus 로고
    • Experimental allergic encephalomyelitis: Neutralizing antibody to TGF-β1 enhances the clinical severity of the disease
    • Johns L. D., and S. Sriram. 1993. Experimental allergic encephalomyelitis: neutralizing antibody to TGF-β1 enhances the clinical severity of the disease. J. Neuroimmunol. 47:1.
    • (1993) J. Neuroimmunol. , vol.47 , pp. 1
    • Johns, L.D.1    Sriram, S.2
  • 59
    • 0026583488 scopus 로고
    • Evidence of endogenous regulatory function of transforming growth factor-β1 in experimental allergic encephalomyelitis
    • Racke, M. K., B. Cannella, P. Albert, M. Sporn, C. S. Raine, and D. E. McFarlin. 1992. Evidence of endogenous regulatory function of transforming growth factor-β1 in experimental allergic encephalomyelitis. Int. Immunol. 4:615.
    • (1992) Int. Immunol. , vol.4 , pp. 615
    • Racke, M.K.1    Cannella, B.2    Albert, P.3    Sporn, M.4    Raine, C.S.5    McFarlin, D.E.6
  • 60
    • 0025892475 scopus 로고
    • Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β1
    • Racke, M. K., S. Dhib-Jalbut, B. Cannella, P. S. Albert, C. S. Raine, and D. E. McFarlin. 1991. Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β1. J. Immunol. 146:3012.
    • (1991) J. Immunol. , vol.146 , pp. 3012
    • Racke, M.K.1    Dhib-Jalbut, S.2    Cannella, B.3    Albert, P.S.4    Raine, C.S.5    McFarlin, D.E.6
  • 61
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen, Y. C., V. K. Kuchroo, J.-I. Inobe, D. A. Hafler, and H. L. Weiner. 1994. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265:1237.
    • (1994) Science , vol.265 , pp. 1237
    • Chen, Y.C.1    Kuchroo, V.K.2    Inobe, J.-I.3    Hafler, D.A.4    Weiner, H.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.