Use of genetically engineered mice in drug discovery and development: Wielding Occam's razor to prune the product portfolio

International Journal of Toxicology

Volumn 21, Issue 1, 2002, Pages 55-64

  Bolon, Brad ^a   Galbreath, Elizabeth ^b  

^a AMGEN INC   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

Drug Discovery; Exploratory Toxicology; Functional Genomics; Knock Out; Mouse; Phenotype; Transgenic

Indexed keywords

MESSENGER RNA;

CONFERENCE PAPER; DRUG RESEARCH; DRUG SCREENING; EXPRESSED SEQUENCE TAG; GENE TARGETING; GENETIC ENGINEERING; KNOCKOUT MOUSE; MOUSE; NONHUMAN; TOXICITY TESTING; TRANSGENIC MOUSE;

ANIMALS; DRUG DESIGN; GENETIC ENGINEERING; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PHENOTYPE;

MUS MUSCULUS;

EID: 0036212445     PISSN: 10915818     EISSN: None     Source Type: Journal    
DOI: 10.1080/10915810252826019     Document Type: Conference Paper

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