Role of gene knockout mice in understanding the mechanisms of chemical toxicity and carcinogenesis

Cancer Letters

Volumn 143, Issue 2, 1999, Pages 199-204

  Gonzalez, Frank J ^a   Kimura, Shioko ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Carcinogenesis; Knockout mice; P450

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; AROMATIC AMINE; BENZENE; CAFFEINE; CARBAMAZEPINE; CARCINOGEN; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; DIMETHYLBENZ[A]ANTHRACENE; DIMETHYLNITROSAMINE DEMETHYLASE; EPOXIDE HYDROLASE; HETEROCYCLIC AMINE; PARACETAMOL; PHENACETIN O DEETHYLASE; PHENYTOIN; POLYCYCLIC AROMATIC HYDROCARBON; SULFOTRANSFERASE; TRANSFERASE;

ARTICLE; CARCINOGENESIS; CARCINOGENICITY; DNA ADDUCT; ENZYME POLYMORPHISM; HUMAN; KNOCKOUT MOUSE; LIVER MICROSOME METABOLISM; METABOLIC ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; TOXICOKINETICS; XENOBIOTIC METABOLISM;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MICE; MICE, KNOCKOUT; NEOPLASMS, EXPERIMENTAL;

ANIMALIA; MAMMALIA; MUS MUSCULUS; RODENTIA;

EID: 0032775613     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00125-1     Document Type: Article

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