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Volumn 26, Issue 4, 1998, Pages 548-555

An evaluation of the hemizygous transgenic Tg.AC mouse for carcinogenicity testing of pharmaceuticals. II. A genotypic marker that predicts tumorigenic responsiveness

Author keywords

12 O tetradecanoylphorbol 13 acetate; Gene amplification; Genetic instability; Inverted repeat; Palindrome; Southern blot hybridization; Zeta globin

Indexed keywords

PALINDROMIC DNA; PHORBOL 13 ACETATE 12 MYRISTATE;

EID: 0031873002     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339802600411     Document Type: Article
Times cited : (46)

References (11)
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    • Dermal carcinogenicity in transgenic mice: Relative responsiveness of male and female hemizygous and homozygous Tg.AC mice to 12-O-tetradecanoylphorbol 13-acetate (TPA) and benzene
    • this issue
    • Blanchard KT, Ball DJ, Holden HE, Furst SM, Stoltz JH, and Stoll RE (1998). Dermal carcinogenicity in transgenic mice: Relative responsiveness of male and female hemizygous and homozygous Tg.AC mice to 12-O-tetradecanoylphorbol 13-acetate (TPA) and benzene. Toxicol. Pathol. 26: 541-547 (this issue).
    • (1998) Toxicol. Pathol. , vol.26 , pp. 541-547
    • Blanchard, K.T.1    Ball, D.J.2    Holden, H.E.3    Furst, S.M.4    Stoltz, J.H.5    Stoll, R.E.6
  • 5
    • 0028170671 scopus 로고
    • An improved method of genomic DNA extraction for screening transgenic mice
    • Crouse JF, Davis VL, Tally WC, and Korach KS (1994). An improved method of genomic DNA extraction for screening transgenic mice. BioTechniques 17: 1030-1032.
    • (1994) BioTechniques , vol.17 , pp. 1030-1032
    • Crouse, J.F.1    Davis, V.L.2    Tally, W.C.3    Korach, K.S.4
  • 6
    • 0022474735 scopus 로고
    • Large inverted duplications are associated with gene amplification
    • Ford M and Fried M (1986). Large inverted duplications are associated with gene amplification. Cell 45: 425-430.
    • (1986) Cell , vol.45 , pp. 425-430
    • Ford, M.1    Fried, M.2
  • 8
    • 0023959559 scopus 로고
    • The multicopy appearance of a large inverted duplication and the sequence at the inversion joint suggest a new model for gene amplification
    • Hyrien O, Debatisse M, Buttin G, and de Saint Vincent BR (1988). The multicopy appearance of a large inverted duplication and the sequence at the inversion joint suggest a new model for gene amplification. EMBO J. 7: 407-417.
    • (1988) EMBO J. , vol.7 , pp. 407-417
    • Hyrien, O.1    Debatisse, M.2    Buttin, G.3    De Saint Vincent, B.R.4
  • 9
    • 0025647881 scopus 로고
    • v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: Effects of phorbol esters and retinoic acid
    • Leder A, Kuo A, Cardiff RD, Sinn E, and Leder P (1990). v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: Effects of phorbol esters and retinoic acid. Proc. Natl. Acad. Sci. USA 87: 9178-9182.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9178-9182
    • Leder, A.1    Kuo, A.2    Cardiff, R.D.3    Sinn, E.4    Leder, P.5
  • 10
    • 0027237453 scopus 로고
    • Chemically induced skin carcinogensis in a transgenic mouse line (Tg.AC) carrying a v-Ha-ras gene
    • Spalding JW, Momma J, Elwell MR, and Tennant RW (1993). Chemically induced skin carcinogensis in a transgenic mouse line (Tg.AC) carrying a v-Ha-ras gene. Carcinogenesis 14: 1335-1341.
    • (1993) Carcinogenesis , vol.14 , pp. 1335-1341
    • Spalding, J.W.1    Momma, J.2    Elwell, M.R.3    Tennant, R.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.