메뉴 건너뛰기




Volumn 835, Issue 1, 1999, Pages 46-61

Structural and functional neuropathology in transgenic mice with CNS expression of IFN-α

Author keywords

Astrocyte; Interferon; Neurologic disorder; Transgenic

Indexed keywords

ALPHA INTERFERON;

EID: 0033578192     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01328-1     Document Type: Conference Paper
Times cited : (163)

References (81)
  • 3
    • 0025739093 scopus 로고
    • Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities.
    • Samuel C.E. Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology. 183:1991;1-11.
    • (1991) Virology , vol.183 , pp. 1-11
    • Samuel, C.E.1
  • 4
    • 0001139213 scopus 로고
    • Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus
    • Lieberman A.P., Pitha P.M., Shin H.S., Shin M.L. Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Proc. Natl. Acad. Sci. USA. 86:1989;6348-6352.
    • (1989) Proc. Natl. Acad. Sci. USA. , vol.86 , pp. 6348-6352
    • Lieberman, A.P.1    Pitha, P.M.2    Shin, H.S.3    Shin, M.L.4
  • 5
    • 0028261779 scopus 로고
    • Expression of MRP14, 27E10, interferon-α And leukocyte common antigen by reactive microglia in postmortem human brain tissue.
    • Akiyama H., Ikeda K., Katoh M., McGeer E.G., McGeer P.L. Expression of MRP14, 27E10, interferon-α and leukocyte common antigen by reactive microglia in postmortem human brain tissue. J. Neuroimmunol. 50:1994;195-201.
    • (1994) J. Neuroimmunol. , vol.50 , pp. 195-201
    • Akiyama, H.1    Ikeda, K.2    Katoh, M.3    McGeer, E.G.4    McGeer, P.L.5
  • 6
    • 0025114572 scopus 로고
    • Neuromodulative actions of cytokines
    • Blatteis C.M. Neuromodulative actions of cytokines. Yale J. Biol. Med. 63:1990;133-146.
    • (1990) Yale J. Biol. Med. , vol.63 , pp. 133-146
    • Blatteis, C.M.1
  • 7
    • 0031969722 scopus 로고    scopus 로고
    • Is interferon-alpha a neuromodulator?
    • Dafny N. Is interferon-alpha a neuromodulator? Brain Res. Rev. 26:1998;1-15.
    • (1998) Brain Res. Rev. , vol.26 , pp. 1-15
    • Dafny, N.1
  • 8
    • 0028936221 scopus 로고
    • The interferons: Biological effects, mechanisms of action, and use in multiple sclerosis.
    • Weinstock-Guttman B., Ransohoff R.M., Kinkel R.P., Rudick R.A. The interferons: biological effects, mechanisms of action, and use in multiple sclerosis. Ann. Neurol. 37:1995;7-15.
    • (1995) Ann. Neurol. , vol.37 , pp. 7-15
    • Weinstock-Guttman, B.1    Ransohoff, R.M.2    Kinkel, R.P.3    Rudick, R.A.4
  • 9
    • 0024150976 scopus 로고
    • Central nervous system toxicity of interferons and other cytokines
    • Bocci V. Central nervous system toxicity of interferons and other cytokines. J. Biol. Regulators Homeostat. Agents. 2:1988;107-118.
    • (1988) J. Biol. Regulators Homeostat. Agents , vol.2 , pp. 107-118
    • Bocci, V.1
  • 10
    • 0028972864 scopus 로고
    • The Aicardi-Goutieres syndrome (familial, early onset encephalopathy with calcifications of the basal ganglia and chronic cerebrospinal fluid lymphocytosis)
    • Tolmie J.L., Shillito P., Hughes-Benzie R., Stephenson J.B.P. The Aicardi-Goutieres syndrome (familial, early onset encephalopathy with calcifications of the basal ganglia and chronic cerebrospinal fluid lymphocytosis). J. Med. Genet. 32:1995;881-884.
    • (1995) J. Med. Genet. , vol.32 , pp. 881-884
    • Tolmie, J.L.1    Shillito, P.2    Hughes-Benzie, R.3    Stephenson, J.B.P.4
  • 11
    • 0032539575 scopus 로고    scopus 로고
    • Recognizable inherited syndrome of progressive central nervous system degeneration and generalized intracranial calcification with overlapping phenotype of the syndrome of Aicardi and Goutieres.
    • Kumar D., Rittey C., Cameron A.H., Variend S. Recognizable inherited syndrome of progressive central nervous system degeneration and generalized intracranial calcification with overlapping phenotype of the syndrome of Aicardi and Goutieres. Am. J. Med. Genet. 75:1998;508-515.
    • (1998) Am. J. Med. Genet. , vol.75 , pp. 508-515
    • Kumar, D.1    Rittey, C.2    Cameron, A.H.3    Variend, S.4
  • 12
  • 13
    • 0032211097 scopus 로고    scopus 로고
    • Transgenic expression of interferon-a in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.
    • Akwa Y., Hassett D.E., Eloranta M.-L., Sandberg K., Masliah E., Powell H., Whitton J.L., Bloom F.E.B., Campbell I.L. Transgenic expression of interferon-a in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration. J. Immunol. 161:1998;5016-5026.
    • (1998) J. Immunol. , vol.161 , pp. 5016-5026
    • Akwa, Y.1    Hassett, D.E.2    Eloranta, M.-L.3    Sandberg, K.4    Masliah, E.5    Powell, H.6    Whitton, J.L.7    Bloom, F.E.B.8    Campbell, I.L.9
  • 14
    • 0032212260 scopus 로고    scopus 로고
    • Astrocyte-targeted expression of IFN-alpha1 protects mice from acute ocular herpes simplex virus type 1 infection.
    • Carr D.J., Veress L.A., Noisakran S., Campbell I.L. Astrocyte-targeted expression of IFN-alpha1 protects mice from acute ocular herpes simplex virus type 1 infection. J. Immunol. 161:1998;4859-4865.
    • (1998) J. Immunol. , vol.161 , pp. 4859-4865
    • Carr, D.J.1    Veress, L.A.2    Noisakran, S.3    Campbell, I.L.4
  • 15
    • 0024399499 scopus 로고
    • The fine structure of acquired immunodeficiency syndrome encephalopathy
    • Mirra S.S., del Rio C. The fine structure of acquired immunodeficiency syndrome encephalopathy. Arch. Pathol. Lab. Med. 113:1989;858-865.
    • (1989) Arch. Pathol. Lab. Med. , vol.113 , pp. 858-865
    • Mirra, S.S.1    Del Rio, C.2
  • 16
    • 0026647724 scopus 로고
    • Tubuloreticular structures in microglial cells, pericytes and endothelial cells in Alzheimer's disease
    • Wegiel J., Wisniewski H.M. Tubuloreticular structures in microglial cells, pericytes and endothelial cells in Alzheimer's disease. Acta Neuropathol. 83:1992;653-658.
    • (1992) Acta Neuropathol. , vol.83 , pp. 653-658
    • Wegiel, J.1    Wisniewski, H.M.2
  • 20
    • 0024235241 scopus 로고
    • Tubuloreticular reorganization of cytomembranes in cells treated with human alpha interferons
    • Grimley P.M., Ray S., Kostianovsky M., Rupp B., Kang Y.-H., Feldman D. Tubuloreticular reorganization of cytomembranes in cells treated with human alpha interferons. Scanning Microscopy. 2:1988;2141-2151.
    • (1988) Scanning Microscopy , vol.2 , pp. 2141-2151
    • Grimley, P.M.1    Ray, S.2    Kostianovsky, M.3    Rupp, B.4    Kang, Y.-H.5    Feldman, D.6
  • 21
    • 0029016084 scopus 로고
    • Role of interferons and other cytokines in the regulation of the immune response
    • Belardelli F. Role of interferons and other cytokines in the regulation of the immune response. APMIS. 103:1995;161-179.
    • (1995) APMIS , vol.103 , pp. 161-179
    • Belardelli, F.1
  • 23
    • 0029314743 scopus 로고
    • The role of cytokines in multiple sclerosis
    • Arnason B. The role of cytokines in multiple sclerosis. Neurology. 45(Suppl. 6):1995;S54-S55.
    • (1995) Neurology , vol.45 , Issue.SUPPL. 6
    • Arnason, B.1
  • 25
    • 0029919187 scopus 로고    scopus 로고
    • Macrophage/microglial-mediated primary demyelination and motor disease induced by the central nervous system production of interleukin-3 in transgenic mice.
    • Chiang C.-S., Powell H.C., Gold L., Samimi A., Campbell I.L. Macrophage/microglial-mediated primary demyelination and motor disease induced by the central nervous system production of interleukin-3 in transgenic mice. J. Clin. Invest. 97:1996;1512-1524.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1512-1524
    • Chiang, C.-S.1    Powell, H.C.2    Gold, L.3    Samimi, A.4    Campbell, I.L.5
  • 26
    • 0030793527 scopus 로고    scopus 로고
    • Astroglial overproduction of TGF-β1 enhances inflammatory central nervous system disease in transgenic mice.
    • Wyss-Coray T., Borrow P., Brooker M.J., Mucke L. Astroglial overproduction of TGF-β1 enhances inflammatory central nervous system disease in transgenic mice. J. Neuroimmunol. 77:1997;45-50.
    • (1997) J. Neuroimmunol. , vol.77 , pp. 45-50
    • Wyss-Coray, T.1    Borrow, P.2    Brooker, M.J.3    Mucke, L.4
  • 27
    • 0025310383 scopus 로고
    • Actions of interferon alpha and interleukin-1 beta on the glucose-responsive neurons in the ventromedial hypothalamus
    • Kuriyama K., Hori T., Mori T., Nakashima T. Actions of interferon alpha and interleukin-1 beta on the glucose-responsive neurons in the ventromedial hypothalamus. Brain Res. Bull. 24:1990;803-810.
    • (1990) Brain Res. Bull. , vol.24 , pp. 803-810
    • Kuriyama, K.1    Hori, T.2    Mori, T.3    Nakashima, T.4
  • 28
  • 29
    • 0023629366 scopus 로고
    • Naloxone blocks the interferon-α induced changes in hypothalamic neuronal activity.
    • Nakashima T., Hori T., Kuriyama K., Kiyohara T. Naloxone blocks the interferon-α induced changes in hypothalamic neuronal activity. Neurosci. Lett. 82:1987;332-336.
    • (1987) Neurosci. Lett. , vol.82 , pp. 332-336
    • Nakashima, T.1    Hori, T.2    Kuriyama, K.3    Kiyohara, T.4
  • 30
    • 0021172947 scopus 로고
    • Neuropsychiatric manifestations of human leukocyte interferon therapy in patients with cancer
    • Adams F., Quesada J., Gutterman J. Neuropsychiatric manifestations of human leukocyte interferon therapy in patients with cancer. J. Am. Med. Assoc. 252:1984;938-941.
    • (1984) J. Am. Med. Assoc. , vol.252 , pp. 938-941
    • Adams, F.1    Quesada, J.2    Gutterman, J.3
  • 31
    • 0025921602 scopus 로고
    • Persistent neurotoxicity of systemically administered interferon-alpha.
    • Meyers C.A., Scheibel R.S., Forman A.D. Persistent neurotoxicity of systemically administered interferon-alpha. Neurology. 41:1991;672-676.
    • (1991) Neurology , vol.41 , pp. 672-676
    • Meyers, C.A.1    Scheibel, R.S.2    Forman, A.D.3
  • 32
    • 0021074083 scopus 로고
    • Interferon modifies EEG and EEG-like activity recorded from sensory, motor, and limbic system structures in freely behaving rats
    • Dafny N. Interferon modifies EEG and EEG-like activity recorded from sensory, motor, and limbic system structures in freely behaving rats. Neurotoxicology. 4:1983;235-240.
    • (1983) Neurotoxicology , vol.4 , pp. 235-240
    • Dafny, N.1
  • 33
    • 0025600013 scopus 로고
    • Alpha-interferon modifies cortical EEG activity: Dose-dependence and antagonism by naloxone
    • Birmanns B., Saphier D., Abramsky O. Alpha-interferon modifies cortical EEG activity: dose-dependence and antagonism by naloxone. J. Neurol. Sci. 100:1990;22-26.
    • (1990) J. Neurol. Sci. , vol.100 , pp. 22-26
    • Birmanns, B.1    Saphier, D.2    Abramsky, O.3
  • 34
    • 0023851786 scopus 로고
    • Immune response products alter CNS activity: Interferon modulates central opioid functions
    • Dafny N., Lee J.R., Dougherty P.M. Immune response products alter CNS activity: interferon modulates central opioid functions. J. Neurosci. Res. 19:1988;130-139.
    • (1988) J. Neurosci. Res. , vol.19 , pp. 130-139
    • Dafny, N.1    Lee, J.R.2    Dougherty, P.M.3
  • 35
    • 0032484546 scopus 로고    scopus 로고
    • Transgenic mice with cerebral expression of human immunodeficiency virus type-1 coat protein gp120 show divergent changes in short- And long-term potentiation in CA1 hippocampus
    • Krucker T., Toggas S.M., Mucke L., Siggins G.R. Transgenic mice with cerebral expression of human immunodeficiency virus type-1 coat protein gp120 show divergent changes in short- and long-term potentiation in CA1 hippocampus. Neuroscience. 83:1998;691-700.
    • (1998) Neuroscience , vol.83 , pp. 691-700
    • Krucker, T.1    Toggas, S.M.2    Mucke, L.3    Siggins, G.R.4
  • 36
    • 0021701893 scopus 로고
    • Alpha and gamma interferons' effects on cortical and hippocampal neurons: Microiontophoretic application and single cell recording
    • Reyes-Vazquez C., Prieto-Gomez B., Georgiades J.A., Dafny N. Alpha and gamma interferons' effects on cortical and hippocampal neurons: microiontophoretic application and single cell recording. Int. J. Neurosci. 25:1984;113-121.
    • (1984) Int. J. Neurosci. , vol.25 , pp. 113-121
    • Reyes-Vazquez, C.1    Prieto-Gomez, B.2    Georgiades, J.A.3    Dafny, N.4
  • 37
    • 0028604358 scopus 로고
    • Alpha-interferon suppresses food intake and neuronal activity of the lateral hypothalamus
    • Reyes-Vazquez C., Prieto-Gomez B., Dafny N. Alpha-interferon suppresses food intake and neuronal activity of the lateral hypothalamus. Neuropharmacology. 33:1994;1545-1552.
    • (1994) Neuropharmacology , vol.33 , pp. 1545-1552
    • Reyes-Vazquez, C.1    Prieto-Gomez, B.2    Dafny, N.3
  • 39
    • 0027279280 scopus 로고
    • Effects of interferons and hydrogen peroxide on CA3 pyramidal cells in rat hippocampal slice cultures
    • Muller M., Fontana A., Zbinden G., Gahwiler B.H. Effects of interferons and hydrogen peroxide on CA3 pyramidal cells in rat hippocampal slice cultures. Brain Res. 619:1993;157-162.
    • (1993) Brain Res. , vol.619 , pp. 157-162
    • Muller, M.1    Fontana, A.2    Zbinden, G.3    Gahwiler, B.H.4
  • 42
    • 0026538980 scopus 로고
    • Interleukin-1 beta increases synaptic inhibition in rat hippocampal pyramidal neurons in vitro
    • Zeise M.L., Madamba S., Siggins G.R. Interleukin-1 beta increases synaptic inhibition in rat hippocampal pyramidal neurons in vitro. Regul. Pept. 39:1992;1-7.
    • (1992) Regul. Pept. , vol.39 , pp. 1-7
    • Zeise, M.L.1    Madamba, S.2    Siggins, G.R.3
  • 44
    • 0023100231 scopus 로고
    • Epileptiform burst activity induced by potassium in the hippocampus and its regulation by GABA-mediated inhibition
    • Korn S.J., Giacchino J.L., Chamberlin N.L., Dingledine R. Epileptiform burst activity induced by potassium in the hippocampus and its regulation by GABA-mediated inhibition. J. Neurophysiol. 57:1987;325-340.
    • (1987) J. Neurophysiol. , vol.57 , pp. 325-340
    • Korn, S.J.1    Giacchino, J.L.2    Chamberlin, N.L.3    Dingledine, R.4
  • 45
    • 0033054087 scopus 로고    scopus 로고
    • Somatostatin acts in CA1 and CA3 to reduce hippocampal epileptiform activity
    • in press
    • M.K. Tallent, G.R. Siggins, Somatostatin acts in CA1 and CA3 to reduce hippocampal epileptiform activity, J. Neurophysiol. in press (1999).
    • (1999) J. Neurophysiol.
    • Tallent, M.K.1    Siggins, G.R.2
  • 46
    • 0020005069 scopus 로고
    • Long-term synaptic enhancement and short-term potentiation in rat fascia dentata act through different mechanisms
    • McNaughton B.L. Long-term synaptic enhancement and short-term potentiation in rat fascia dentata act through different mechanisms. J. Physiol. 324:1982;249-262.
    • (1982) J. Physiol. , vol.324 , pp. 249-262
    • McNaughton, B.L.1
  • 47
    • 0024584901 scopus 로고
    • Evidence that changes in presynaptic calcium currents are not responsible for long-term potentiation in hippocampus
    • Muller D., Lynch G. Evidence that changes in presynaptic calcium currents are not responsible for long-term potentiation in hippocampus. Brain Res. 479:1989;290-299.
    • (1989) Brain Res. , vol.479 , pp. 290-299
    • Muller, D.1    Lynch, G.2
  • 48
    • 0028040045 scopus 로고
    • Presynaptic calcium is increased during normal synaptic transmission and paired-pulse facilitation, but not in long-term potentiation in area CA1 of hippocampus.
    • Wu L.G., Saggau P. Presynaptic calcium is increased during normal synaptic transmission and paired-pulse facilitation, but not in long-term potentiation in area CA1 of hippocampus. J. Neurosci. 14:1994;645-654.
    • (1994) J. Neurosci. , vol.14 , pp. 645-654
    • Wu, L.G.1    Saggau, P.2
  • 49
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • Bliss T., Collingridge G.L. A synaptic model of memory: Long-term potentiation in the hippocampus. Nature. 361:1993;31-39.
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.1    Collingridge, G.L.2
  • 50
    • 0022461953 scopus 로고
    • Postsynaptic hyperpolarization during conditioning reversibly blocks induction of long-term potentiation
    • Malinow R., Miller J.P. Postsynaptic hyperpolarization during conditioning reversibly blocks induction of long-term potentiation. Nature. 320:1986;529-530.
    • (1986) Nature , vol.320 , pp. 529-530
    • Malinow, R.1    Miller, J.P.2
  • 52
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
    • Morris R.G.M., Anderson E., Lynch G.S., Baudry M. Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature. 359:1986;774-776.
    • (1986) Nature , vol.359 , pp. 774-776
    • Morris, R.G.M.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 53
    • 0026637195 scopus 로고
    • Deficient hippocampal long-term potentiation in α-calcium-calmodulin kinase II mutant mice.
    • Silva A.J., Stevens C.F., Tonegawa S., Wang Y. Deficient hippocampal long-term potentiation in α-calcium-calmodulin kinase II mutant mice. Science. 257:1992;201-206.
    • (1992) Science , vol.257 , pp. 201-206
    • Silva, A.J.1    Stevens, C.F.2    Tonegawa, S.3    Wang, Y.4
  • 54
    • 0027332670 scopus 로고
    • Interleukin 1 beta inhibits synaptic strength and long-term potentiation in the rat CA1 hippocampus.
    • Bellinger F., Madamba S., Siggins G. Interleukin 1 beta inhibits synaptic strength and long-term potentiation in the rat CA1 hippocampus. Brain Res. 628:1993;227-234.
    • (1993) Brain Res. , vol.628 , pp. 227-234
    • Bellinger, F.1    Madamba, S.2    Siggins, G.3
  • 55
    • 0028843876 scopus 로고
    • Reduced long-term potentiation in the dentate gyrus of transgenic mice with cerebral overexpression of interleukin-6.
    • Bellinger F.P., Madamba S.G., Campbell I.L., Siggins G. Reduced long-term potentiation in the dentate gyrus of transgenic mice with cerebral overexpression of interleukin-6. Neurosci. Lett. 198:1995;95-98.
    • (1995) Neurosci. Lett. , vol.198 , pp. 95-98
    • Bellinger, F.P.1    Madamba, S.G.2    Campbell, I.L.3    Siggins, G.4
  • 56
    • 0025367157 scopus 로고
    • Interleukin-1 beta inhibits long-term potentiation in the CA3 region of mouse hippocampal slices
    • Katsuki H., Nakai S., Hirai Y., Akaji K., Kiso Y., Satoh M. Interleukin-1 beta inhibits long-term potentiation in the CA3 region of mouse hippocampal slices. Eur J Pharmacol. 181:1990;323-326.
    • (1990) Eur J Pharmacol , vol.181 , pp. 323-326
    • Katsuki, H.1    Nakai, S.2    Hirai, Y.3    Akaji, K.4    Kiso, Y.5    Satoh, M.6
  • 57
    • 0031049044 scopus 로고    scopus 로고
    • Interleukin-6 inhibits long-term potentiation in rat hippocampal slices
    • Li A.-J., Katafuchi T., Oda S., Hori T., Oomura Y. Interleukin-6 inhibits long-term potentiation in rat hippocampal slices. Brain Res. 748:1997;30-38.
    • (1997) Brain Res. , vol.748 , pp. 30-38
    • Li, A.-J.1    Katafuchi, T.2    Oda, S.3    Hori, T.4    Oomura, Y.5
  • 58
    • 78651155696 scopus 로고
    • Location of presynaptic inhibitory synapses on hippocampus pyramids
    • Andersen P., Eccles J.C., Loyning Y. Location of presynaptic inhibitory synapses on hippocampus pyramids. J. Neurophysiol. 27:1964;592-607.
    • (1964) J. Neurophysiol. , vol.27 , pp. 592-607
    • Andersen, P.1    Eccles, J.C.2    Loyning, Y.3
  • 59
    • 78651143083 scopus 로고
    • Pathway of postsynaptic inhibition in the hippocampus
    • Andersen P., Eccles J.C., Loyning Y. Pathway of postsynaptic inhibition in the hippocampus. J. Neurophysiol. 27:1964;608-619.
    • (1964) J. Neurophysiol. , vol.27 , pp. 608-619
    • Andersen, P.1    Eccles, J.C.2    Loyning, Y.3
  • 60
    • 0020001035 scopus 로고
    • Feed-forward dendritic inhibition in rat hippocampal pyramidal cells studied in vitro
    • Alger B.E., Nicoll R.A. Feed-forward dendritic inhibition in rat hippocampal pyramidal cells studied in vitro. J. Physiol. (London). 328:1982;105-123.
    • (1982) J. Physiol. (London) , vol.328 , pp. 105-123
    • Alger, B.E.1    Nicoll, R.A.2
  • 61
    • 0022270903 scopus 로고
    • Gamma-aminobutyric acid reuptake and the termination of inhibitory synaptic potentials in the rat hippocampal slice
    • Dingledine R., Korn S.J. Gamma-aminobutyric acid reuptake and the termination of inhibitory synaptic potentials in the rat hippocampal slice. J. Physiol. (London). 366:1985;387-409.
    • (1985) J. Physiol. (London) , vol.366 , pp. 387-409
    • Dingledine, R.1    Korn, S.J.2
  • 62
    • 0025289221 scopus 로고
    • Similarities in circuitry between Ammon's horn and dentate gyrus: Local interactions and parallel processing
    • Schwartzkroin P.A., Scharfman H.E., Sloviter R.S. Similarities in circuitry between Ammon's horn and dentate gyrus: local interactions and parallel processing. Prog. Brain Res. 83:1990;269-286.
    • (1990) Prog. Brain Res. , vol.83 , pp. 269-286
    • Schwartzkroin, P.A.1    Scharfman, H.E.2    Sloviter, R.S.3
  • 63
    • 0028298627 scopus 로고
    • Site-specific hippocampal pathophysiology due to cerebral overexpression of interleukin-6 in transgenic mice
    • Steffensen S.C., Campbell I.L., Henriksen S.J. Site-specific hippocampal pathophysiology due to cerebral overexpression of interleukin-6 in transgenic mice. Brain Res. 652:1994;149-153.
    • (1994) Brain Res. , vol.652 , pp. 149-153
    • Steffensen, S.C.1    Campbell, I.L.2    Henriksen, S.J.3
  • 64
    • 0001767549 scopus 로고
    • Cholinesterase-containing systems of the brain of the rat
    • Shute C.C.D., Lewis P.R. Cholinesterase-containing systems of the brain of the rat. Nature. 199:1963;1160-1164.
    • (1963) Nature , vol.199 , pp. 1160-1164
    • Shute, C.C.D.1    Lewis, P.R.2
  • 65
    • 0015729695 scopus 로고
    • The distribution of septal projections to the hippocampus of the rat
    • Mosko S., Lynch G., Cotman C.W. The distribution of septal projections to the hippocampus of the rat. J. Comp. Neurol. 152:1973;163-174.
    • (1973) J. Comp. Neurol. , vol.152 , pp. 163-174
    • Mosko, S.1    Lynch, G.2    Cotman, C.W.3
  • 66
    • 0018774210 scopus 로고
    • The connections of the septal region in the rat
    • Swanson L.W., Cowan W.M. The connections of the septal region in the rat. J. Comp. Neurol. 186:1979;621-656.
    • (1979) J. Comp. Neurol. , vol.186 , pp. 621-656
    • Swanson, L.W.1    Cowan, W.M.2
  • 67
    • 0024513345 scopus 로고
    • Neuronal activity in the subcortically denervated hippocampus: A chronic model for epilepsy
    • Buzsaki G., Ponomareff G.L., Bayardo F., Ruiz R., Gage F.H. Neuronal activity in the subcortically denervated hippocampus: A chronic model for epilepsy. Neuroscience. 28:1989;527-538.
    • (1989) Neuroscience , vol.28 , pp. 527-538
    • Buzsaki, G.1    Ponomareff, G.L.2    Bayardo, F.3    Ruiz, R.4    Gage, F.H.5
  • 68
    • 0027457931 scopus 로고
    • Biochemical and morphological changes in the rat hippocampus following transection of the fimbria-fornix
    • Lahtinen H., Miettinen R., Ylinen A., Halonen T., Riekkinen P.J. Biochemical and morphological changes in the rat hippocampus following transection of the fimbria-fornix. Brain Res. Bull. 31:1993;311-318.
    • (1993) Brain Res. Bull. , vol.31 , pp. 311-318
    • Lahtinen, H.1    Miettinen, R.2    Ylinen, A.3    Halonen, T.4    Riekkinen, P.J.5
  • 69
    • 0025005423 scopus 로고
    • An animal model for the behavioral effects of interferon
    • Segall M., Crnic L. An animal model for the behavioral effects of interferon. Behav. Neurosci. 104:1990;612-618.
    • (1990) Behav. Neurosci. , vol.104 , pp. 612-618
    • Segall, M.1    Crnic, L.2
  • 70
    • 0027284320 scopus 로고
    • Repeated injections of interferon-alpha A/D in Balb/c mice: Behavioral effects
    • Dunn A., Crnic L. Repeated injections of interferon-alpha A/D in Balb/c mice: behavioral effects. Brain Behav. Immunol. 7:1993;104-111.
    • (1993) Brain Behav. Immunol. , vol.7 , pp. 104-111
    • Dunn, A.1    Crnic, L.2
  • 73
    • 0020662970 scopus 로고
    • Neurological effects of recombinant human interferon
    • Smedley H., Katrak M., Sikora K., Wheeler T. Neurological effects of recombinant human interferon. Br. Med. J. 286:1983;262-264.
    • (1983) Br. Med. J. , vol.286 , pp. 262-264
    • Smedley, H.1    Katrak, M.2    Sikora, K.3    Wheeler, T.4
  • 74
    • 0031028141 scopus 로고    scopus 로고
    • Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin-6 in the brain.
    • Heyser C.J., Masliah E., Samimi A., Campbell I.L., Gold L.H. Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin-6 in the brain. Proc. Natl. Acad. Sci. USA. 94:1997;1500-1505.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 1500-1505
    • Heyser, C.J.1    Masliah, E.2    Samimi, A.3    Campbell, I.L.4    Gold, L.H.5
  • 75
    • 0030840532 scopus 로고    scopus 로고
    • Deficits in discriminated learning remain despite clearance of long-term persistent viral infection in mice.
    • Brot M.D., Rall G.F., Oldstone M.B.A., Koob G.F., Gold L.H. Deficits in discriminated learning remain despite clearance of long-term persistent viral infection in mice. J. Neurovirol. 3:1997;265-273.
    • (1997) J. Neurovirol. , vol.3 , pp. 265-273
    • Brot, M.D.1    Rall, G.F.2    Oldstone, M.B.A.3    Koob, G.F.4    Gold, L.H.5
  • 76
    • 0029954252 scopus 로고    scopus 로고
    • Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells
    • de la Torre J., Mallory M., Brot M., Gold L., Koob G., Oldstone M., Masliah E. Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells. Virology. 220:1996;508-515.
    • (1996) Virology , vol.220 , pp. 508-515
    • De La Torre, J.1    Mallory, M.2    Brot, M.3    Gold, L.4    Koob, G.5    Oldstone, M.6    Masliah, E.7
  • 77
    • 0029012902 scopus 로고
    • Pattern of neurobehavioral deficits associated with interferon alfa therapy for leukemia
    • Pavol M., Meyers C., Rexer J., Valentine A., Mattis P., Talpaz M. Pattern of neurobehavioral deficits associated with interferon alfa therapy for leukemia. Neurology. 45:1995;947-950.
    • (1995) Neurology , vol.45 , pp. 947-950
    • Pavol, M.1    Meyers, C.2    Rexer, J.3    Valentine, A.4    Mattis, P.5    Talpaz, M.6
  • 78
    • 0025241459 scopus 로고
    • A test of conditioned taste aversion with mouse interferon-alpha
    • Segall M., Crnic L. A test of conditioned taste aversion with mouse interferon-alpha. Brain Behav. Immunol. 4:1990;223-231.
    • (1990) Brain Behav. Immunol. , vol.4 , pp. 223-231
    • Segall, M.1    Crnic, L.2
  • 80
    • 0021852049 scopus 로고
    • Intrathecal sythesis of different alpha-interferons in patients with various neurological diseases
    • Dussaix E., Lebon P., Ponsot G., Huault G., Tardieu M. Intrathecal sythesis of different alpha-interferons in patients with various neurological diseases. Acta Neurol. Scand. 7:1985;504-509.
    • (1985) Acta Neurol. Scand. , vol.7 , pp. 504-509
    • Dussaix, E.1    Lebon, P.2    Ponsot, G.3    Huault, G.4    Tardieu, M.5
  • 81
    • 0032946030 scopus 로고    scopus 로고
    • Chemokines and the inflammatory response to viral infection in the central nervous system with a focus on lymphocytic choriomeningitis virus.
    • Asensio V.C., Kincaid C., Campbell I.L. Chemokines and the inflammatory response to viral infection in the central nervous system with a focus on lymphocytic choriomeningitis virus. J. Neurovirol. 5:1999;65-75.
    • (1999) J. Neurovirol. , vol.5 , pp. 65-75
    • Asensio, V.C.1    Kincaid, C.2    Campbell, I.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.