-
1
-
-
0024353079
-
TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann, T. R. and Coffman, R. L., TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties, Annu. Rev. Immunol., 7, 145, 1989.
-
(1989)
Annu. Rev. Immunol.
, vol.7
, pp. 145
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
2
-
-
0027349464
-
Tumor necrosis factor/cachectin as an effector of T cell-dependent immunopathology
-
Grau, G. E., Lambert, P. H., Vassalli, P., and Piguet, P. F., Tumor necrosis factor/cachectin as an effector of T cell-dependent immunopathology, Int. Rev. Exp. Pathol., 34, 159, 1993.
-
(1993)
Int. Rev. Exp. Pathol.
, vol.34
, pp. 159
-
-
Grau, G.E.1
Lambert, P.H.2
Vassalli, P.3
Piguet, P.F.4
-
3
-
-
0028053599
-
Human Fas ligand: Gene structure, chromosomal location and species specificity
-
Takahashi, T., Tanaka, M., Inazawa, J., Abe, T., Suda, T., and Nagata, S., Human Fas ligand: gene structure, chromosomal location and species specificity, Int. Immunol., 6(10), 1567, 1994.
-
(1994)
Int. Immunol.
, vol.6
, Issue.10
, pp. 1567
-
-
Takahashi, T.1
Tanaka, M.2
Inazawa, J.3
Abe, T.4
Suda, T.5
Nagata, S.6
-
4
-
-
0028927607
-
The Fas death factor
-
Nagata, S. and Golstein, P., The Fas death factor, Science, 267(5203), 1449, 1995.
-
(1995)
Science
, vol.267
, Issue.5203
, pp. 1449
-
-
Nagata, S.1
Golstein, P.2
-
5
-
-
0028671833
-
Fas and Fas ligand: A death factor and its receptor
-
Nagata, S., Fas and Fas ligand: a death factor and its receptor, Adv. Immunol., 57(129), 129, 1994.
-
(1994)
Adv. Immunol.
, vol.57
, Issue.129
, pp. 129
-
-
Nagata, S.1
-
6
-
-
0028107190
-
A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice
-
Miyawaki, S., Nakamura, Y., Suzuka, H., Koba, M., Yasumizu, R., Ikehara, S., and Shibata, Y., A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice, Eur. J. Immunol., 24(2), 429, 1994.
-
(1994)
Eur. J. Immunol.
, vol.24
, Issue.2
, pp. 429
-
-
Miyawaki, S.1
Nakamura, Y.2
Suzuka, H.3
Koba, M.4
Yasumizu, R.5
Ikehara, S.6
Shibata, Y.7
-
7
-
-
0028280560
-
T-cell development and function in gene-knockout mice
-
Yeung, R. S., Penninger, J., and Mak, T. W., T-cell development and function in gene-knockout mice, Curr. Opin. Immunol., 6(2), 298, 1994.
-
(1994)
Curr. Opin. Immunol.
, vol.6
, Issue.2
, pp. 298
-
-
Yeung, R.S.1
Penninger, J.2
Mak, T.W.3
-
8
-
-
0028059099
-
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
-
Gu, H., Marth, J. D., Orban, P. C., Mossmann, H., and Rajewsky, K., Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting [see comments], Science, 265(5168), 103, 1994.
-
(1994)
Science
, vol.265
, Issue.5168
, pp. 103
-
-
Gu, H.1
Marth, J.D.2
Orban, P.C.3
Mossmann, H.4
Rajewsky, K.5
-
9
-
-
0025899598
-
Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
-
Schorle, H., Holtschke, T., Hunig, T., Schimpl, A., and Horak, I., Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting, Nature (London), 352(6336), 621, 1991.
-
(1991)
Nature (London)
, vol.352
, Issue.6336
, pp. 621
-
-
Schorle, H.1
Holtschke, T.2
Hunig, T.3
Schimpl, A.4
Horak, I.5
-
10
-
-
0027688772
-
Immune responses in interleukin-2-deficient mice
-
Kundig, T. M., Schorle, H., Bachmann, M. F., Hengartner, H., Zinkernagel, R. M., and Horak, I., Immune responses in interleukin-2-deficient mice, Science, 262(5136), 1059, 1993.
-
(1993)
Science
, vol.262
, Issue.5136
, pp. 1059
-
-
Kundig, T.M.1
Schorle, H.2
Bachmann, M.F.3
Hengartner, H.4
Zinkernagel, R.M.5
Horak, I.6
-
11
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
Sadlack, B., Merz, H., Schorle, H., Schimpl, A., Feller, A. C., and Horak, I., Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene [see comments], Cell, 75(2), 253, 1993.
-
(1993)
Cell
, vol.75
, Issue.2
, pp. 253
-
-
Sadlack, B.1
Merz, H.2
Schorle, H.3
Schimpl, A.4
Feller, A.C.5
Horak, I.6
-
12
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K., and Muller, W., Interleukin-10-deficient mice develop chronic enterocolitis [see comments], Cell, 75(2), 263, 1993.
-
(1993)
Cell
, vol.75
, Issue.2
, pp. 263
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
13
-
-
0027422089
-
Chronic intestinal inflammation: An unexpected outcome in cytokine or T cell receptor mutant mice
-
Strober, W. and Ehrhardt, R. O., Chronic intestinal inflammation: an unexpected outcome in cytokine or T cell receptor mutant mice [comment], Cell, 75(2), 203, 1993.
-
(1993)
Cell
, vol.75
, Issue.2
, pp. 203
-
-
Strober, W.1
Ehrhardt, R.O.2
-
14
-
-
0028878330
-
Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain
-
DiSanto, J. P., Muller, W., Guy-Grand, D., Fischer, A., and Rajewsky, K., Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain, Proc. Natl. Acad. Sci. U. S. A., 92(2), 377, 1995.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, Issue.2
, pp. 377
-
-
DiSanto, J.P.1
Muller, W.2
Guy-Grand, D.3
Fischer, A.4
Rajewsky, K.5
-
15
-
-
0028925778
-
Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain
-
Cao, X., Shores, E., Hu-Li, J., Anver, M., and Keisall, B., Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain, Immunity, 2, 223, 1995.
-
(1995)
Immunity
, vol.2
, pp. 223
-
-
Cao, X.1
Shores, E.2
Hu-Li, J.3
Anver, M.4
Keisall, B.5
-
16
-
-
0029028363
-
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
-
Suzuki, H., Kundig, T., Furlonger, C., Wakeham, A., Taniguchi, T., Page, C., and Mak, T., Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta, Science, 268, 1472, 1995.
-
(1995)
Science
, vol.268
, pp. 1472
-
-
Suzuki, H.1
Kundig, T.2
Furlonger, C.3
Wakeham, A.4
Taniguchi, T.5
Page, C.6
Mak, T.7
-
17
-
-
0026328818
-
Generation and analysis of interleukin-4 deficient mice
-
Kuhn, R., Rajewsky, K., and Muller, W., Generation and analysis of interleukin-4 deficient mice, Science, 254(5032), 707, 1991.
-
(1991)
Science
, vol.254
, Issue.5032
, pp. 707
-
-
Kuhn, R.1
Rajewsky, K.2
Muller, W.3
-
18
-
-
0027452977
-
Disruption of the murine IL-4 gene blocks Th2 cytokine responses
-
Kopf, M., Le-Gros, G., Bachmann, M., Lamers, M. C., Bluethmann, H., and Kohler, G., Disruption of the murine IL-4 gene blocks Th2 cytokine responses, Nature (London), 362(6417), 245, 1993.
-
(1993)
Nature (London)
, vol.362
, Issue.6417
, pp. 245
-
-
Kopf, M.1
Le-Gros, G.2
Bachmann, M.3
Lamers, M.C.4
Bluethmann, H.5
Kohler, G.6
-
19
-
-
0028906467
-
Impaired mucosul immune responses in interleukin 4-targeted mice
-
Vajdy, M., Kosco, V. M., Kopf, M., Kohler, G., and Lycke, N., Impaired mucosul immune responses in interleukin 4-targeted mice, J. Exp. Med., 181(1), 41, 1995.
-
(1995)
J. Exp. Med.
, vol.181
, Issue.1
, pp. 41
-
-
Vajdy, M.1
Kosco, V.M.2
Kopf, M.3
Kohler, G.4
Lycke, N.5
-
20
-
-
0345317621
-
IgG1 plasmacytosis in interleukin 6 transgenic mice
-
Suematsu, S., Matsuda, T., Aozasa, K., Akira, S., Nakano, N., Ohno, S., Miyazaki, J., Yamamura, K., Hirano, T., and Kishimoto, T., IgG1 plasmacytosis in interleukin 6 transgenic mice, Proc. Natl. Acad. Sci. U. S. A., 86(19), 7547, 1989.
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, Issue.19
, pp. 7547
-
-
Suematsu, S.1
Matsuda, T.2
Aozasa, K.3
Akira, S.4
Nakano, N.5
Ohno, S.6
Miyazaki, J.7
Yamamura, K.8
Hirano, T.9
Kishimoto, T.10
-
21
-
-
0028997843
-
Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice
-
Hirota, H., Yoshida, K., Kishimoto, T., and Taga, T., Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice, Proc. Natl. Acad. Sci. U. S. A., 92(11), 4862, 1995.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, Issue.11
, pp. 4862
-
-
Hirota, H.1
Yoshida, K.2
Kishimoto, T.3
Taga, T.4
-
22
-
-
0027344217
-
Pathology induced by interleukin-6
-
Ryffel, B., Mihatsch, M. J., and Woerly, G., Pathology induced by interleukin-6, Int. Rev. Exp. Pathol., 34, 79, 1993.
-
(1993)
Int. Rev. Exp. Pathol.
, vol.34
, pp. 79
-
-
Ryffel, B.1
Mihatsch, M.J.2
Woerly, G.3
-
23
-
-
0028156156
-
Long-term interleukin-6 administration stimulates sustained thrombopoiesis and acute-phase protein synthesis in a small primate - The marmoset
-
Ryffel, B., Car, B. D., Woerly, G., Weber, M., DiPadova, F., Kammuller, M., Klug, S., Neubert, R., and Neubert, D., Long-term interleukin-6 administration stimulates sustained thrombopoiesis and acute-phase protein synthesis in a small primate - the marmoset, Blood, 83(8), 2093, 1994.
-
(1994)
Blood
, vol.83
, Issue.8
, pp. 2093
-
-
Ryffel, B.1
Car, B.D.2
Woerly, G.3
Weber, M.4
DiPadova, F.5
Kammuller, M.6
Klug, S.7
Neubert, R.8
Neubert, D.9
-
24
-
-
0028328436
-
Impaired immune and acute-phase responses in interleukin-6-deficient mice
-
Kopf, M., Baumann, H., Freer, G., Freudenberg, M., Lamers, M., Kishimoto, T., Zinkernagel, R., Bluethmann, H., and Kohler, G., Impaired immune and acute-phase responses in interleukin-6-deficient mice, Nature (London), 368(6469), 339, 1994.
-
(1994)
Nature (London)
, vol.368
, Issue.6469
, pp. 339
-
-
Kopf, M.1
Baumann, H.2
Freer, G.3
Freudenberg, M.4
Lamers, M.5
Kishimoto, T.6
Zinkernagel, R.7
Bluethmann, H.8
Kohler, G.9
-
25
-
-
0027984754
-
Defective inflammatory response in interleukin 6-deficient mice
-
Fattori, E., Cappelletti, M., Costa, P., Sellitto, C., Cantoni, L., Carelli, M., Faggioni, R., Fantuzzi, G., Ghezzi, P., and Poli, V., Defective inflammatory response in interleukin 6-deficient mice, J. Exp. Med., 180(4), 1243, 1994.
-
(1994)
J. Exp. Med.
, vol.180
, Issue.4
, pp. 1243
-
-
Fattori, E.1
Cappelletti, M.2
Costa, P.3
Sellitto, C.4
Cantoni, L.5
Carelli, M.6
Faggioni, R.7
Fantuzzi, G.8
Ghezzi, P.9
Poli, V.10
-
26
-
-
0028242234
-
The role of interleukin-6 in mucosal IgA antibody responses in vivo
-
Ramsay, A. J., Husband, A. J., Ramshaw, I. A., Bao, S., Matthaei, K. I., Koehler, G., and Kopf, M., The role of interleukin-6 in mucosal IgA antibody responses in vivo, Science, 264(5158), 561, 1994.
-
(1994)
Science
, vol.264
, Issue.5158
, pp. 561
-
-
Ramsay, A.J.1
Husband, A.J.2
Ramshaw, I.A.3
Bao, S.4
Matthaei, K.I.5
Koehler, G.6
Kopf, M.7
-
27
-
-
0028266906
-
Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion
-
Poli, V., Balena, R., Fattori, E., Markatos, A., Yamamoto, M., Tanaka, H., Ciliberto, G., Rodan, G. A., and Costantini, F., Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion, Embo. J., 13(5), 1189, 1994.
-
(1994)
Embo. J.
, vol.13
, Issue.5
, pp. 1189
-
-
Poli, V.1
Balena, R.2
Fattori, E.3
Markatos, A.4
Yamamoto, M.5
Tanaka, H.6
Ciliberto, G.7
Rodan, G.A.8
Costantini, F.9
-
28
-
-
0028853334
-
Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages
-
Tanaka, T., Akira, S., Yoshida, K., Umemoto, M., Yoneda, Y., Shirafuji, N., Fujiwara, H., Suematsu, S., Yoshida, N., and Kishimoto, T., Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages, Cell, 80(2), 353, 1995.
-
(1995)
Cell
, vol.80
, Issue.2
, pp. 353
-
-
Tanaka, T.1
Akira, S.2
Yoshida, K.3
Umemoto, M.4
Yoneda, Y.5
Shirafuji, N.6
Fujiwara, H.7
Suematsu, S.8
Yoshida, N.9
Kishimoto, T.10
-
29
-
-
9044222888
-
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders
-
Yoshida, K., Taga, T., Saito, M., Suematsu, S., Kumanogoh, A., Tanaka, T., Fujiwara, H., Hirata, M., Yamagami, T., Nakahata, T., Hirabayashi, T., Yoneda, Y., Tanaka, K., Wang, W. Z., Mori, C., Shiota, K., Yoshida, N., and Kishimoto, T., Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders, Proc. Natl. Acad. Sci. U. S. A., 93(1), 407, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, Issue.1
, pp. 407
-
-
Yoshida, K.1
Taga, T.2
Saito, M.3
Suematsu, S.4
Kumanogoh, A.5
Tanaka, T.6
Fujiwara, H.7
Hirata, M.8
Yamagami, T.9
Nakahata, T.10
Hirabayashi, T.11
Yoneda, Y.12
Tanaka, K.13
Wang, W.Z.14
Mori, C.15
Shiota, K.16
Yoshida, N.17
Kishimoto, T.18
-
30
-
-
0028929565
-
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
-
von Freeden Jeffry, U., Vieira, P., Lucian, L. A., McNeil, T., Burdach, S. E., and Murray, R., Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine, J. Exp. Med., 181(4), 1519, 1995.
-
(1995)
J. Exp. Med.
, vol.181
, Issue.4
, pp. 1519
-
-
Von Freeden Jeffry, U.1
Vieira, P.2
Lucian, L.A.3
McNeil, T.4
Burdach, S.E.5
Murray, R.6
-
31
-
-
0028043326
-
Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
-
Trinchieri, G., Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes, Blood, 84(12), 4008, 1994.
-
(1994)
Blood
, vol.84
, Issue.12
, pp. 4008
-
-
Trinchieri, G.1
-
32
-
-
0028012527
-
Interleukin-12
-
Brunda, M. J., Interleukin-12, J. Leukoc. Biol., 55(2), 280, 1994.
-
(1994)
J. Leukoc. Biol.
, vol.55
, Issue.2
, pp. 280
-
-
Brunda, M.J.1
-
33
-
-
0028183408
-
The molecular basis of X-linked severe combined immunodeficiency: The role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c
-
Leonard, W. J., Noguchi, M., Russell, S. M., and McBride, O. W., The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor gamma chain as a common gamma chain, gamma c, Immunol Rev. 138, 61, 1994.
-
(1994)
Immunol Rev.
, vol.138
, pp. 61
-
-
Leonard, W.J.1
Noguchi, M.2
Russell, S.M.3
McBride, O.W.4
-
34
-
-
0024791129
-
Cloning of murine interferon gamma receptor cDNA: Expression in human cells mediates high-affinity binding but is not sufficient to confer sensitivity to murine interferon gamma
-
Hemmi, S., Peghini, P., Metzler, M., Merlin, G., Dembic, Z., and Aguet, M., Cloning of murine interferon gamma receptor cDNA: expression in human cells mediates high-affinity binding but is not sufficient to confer sensitivity to murine interferon gamma, Proc. Natl. Acad. Sci. U. S. A., 86(24), 9901, 1989.
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, Issue.24
, pp. 9901
-
-
Hemmi, S.1
Peghini, P.2
Metzler, M.3
Merlin, G.4
Dembic, Z.5
Aguet, M.6
-
35
-
-
0028219965
-
A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells
-
Hemmi, S., Bohni, R., Stark, G., Di-Marco, F., and Aguet, M., A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells, Cell, 76(5), 803, 1994.
-
(1994)
Cell
, vol.76
, Issue.5
, pp. 803
-
-
Hemmi, S.1
Bohni, R.2
Stark, G.3
Di-Marco, F.4
Aguet, M.5
-
36
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
Darnell, J., Jr., Kerr, I. M., and Stark, G. R., Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins, Science, 264(5164), 1415, 1994.
-
(1994)
Science
, vol.264
, Issue.5164
, pp. 1415
-
-
Darnell Jr., J.1
Kerr, I.M.2
Stark, G.R.3
-
37
-
-
0027400726
-
Multiple defects of immune cell function in mice with disrupted interferon-gamma genes
-
Dalton, D. K., Pitts-Meek, S., Keshav, S., Figari, I. S., Bradley, A., and Stewart, T. A., Multiple defects of immune cell function in mice with disrupted interferon-gamma genes [see comments], Science, 259(5102), 1739, 1993.
-
(1993)
Science
, vol.259
, Issue.5102
, pp. 1739
-
-
Dalton, D.K.1
Pitts-Meek, S.2
Keshav, S.3
Figari, I.S.4
Bradley, A.5
Stewart, T.A.6
-
38
-
-
0027464928
-
Immune response in mice that lack the interteron-gamma receptor
-
Huang, S., Hendriks, W., Althage, A., Hemmi, S., Bluethmann, H., Kamijo, R., Vilcek, J., Zinkernagel, R. M., and Aguet, M., Immune response in mice that lack the interteron-gamma receptor [see comments], Science, 259(5102), 1742, 1993.
-
(1993)
Science
, vol.259
, Issue.5102
, pp. 1742
-
-
Huang, S.1
Hendriks, W.2
Althage, A.3
Hemmi, S.4
Bluethmann, H.5
Kamijo, R.6
Vilcek, J.7
Zinkernagel, R.M.8
Aguet, M.9
-
39
-
-
0028070714
-
Functional role of type I and type II interferons in antiviral defense
-
Muller, U., Steinhoff, U., Reis, L. F., Hemmi, S., Pavlovic, J., Zinkernagel, R. M., and Aguet, M., Functional role of type I and type II interferons in antiviral defense, Science, 264(5167), 1918, 1994.
-
(1994)
Science
, vol.264
, Issue.5167
, pp. 1918
-
-
Muller, U.1
Steinhoff, U.2
Reis, L.F.3
Hemmi, S.4
Pavlovic, J.5
Zinkernagel, R.M.6
Aguet, M.7
-
40
-
-
0028263504
-
Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis
-
Dranoff, G., Crawford, A. D., Sadelain, M., Ream, B., Rashid, A., Bronson, R. T., Dickersin, G. R., Bachurski, C. J., Mark, E. L., Whitsett, J. A., et al., Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis, Science, 264(5159), 713, 1994.
-
(1994)
Science
, vol.264
, Issue.5159
, pp. 713
-
-
Dranoff, G.1
Crawford, A.D.2
Sadelain, M.3
Ream, B.4
Rashid, A.5
Bronson, R.T.6
Dickersin, G.R.7
Bachurski, C.J.8
Mark, E.L.9
Whitsett, J.A.10
-
41
-
-
0028236526
-
Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology
-
Stanley, E., Lieschke, G. J., Grail, D., Metcalf, D., Hodgson, G., Gall, J. A., Maher, D. W., Cebon, J., Sinickas, V., and Dunn, A. R., Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology, Proc. Natl. Acad. Sci. U. S. A., 91(12), 5592, 1994.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, Issue.12
, pp. 5592
-
-
Stanley, E.1
Lieschke, G.J.2
Grail, D.3
Metcalf, D.4
Hodgson, G.5
Gall, J.A.6
Maher, D.W.7
Cebon, J.8
Sinickas, V.9
Dunn, A.R.10
-
42
-
-
0028261070
-
Mice lacking both macrophage- And granulocyte-macrophage colony-stimulating factor have macrophages and coexistent osteopetrosis and severe lung disease
-
Lieschke, G. J., Stanley, E., Grail, D., Hodgson, G., Sinickas, V., Gall, J. A., Sinclair, R. A., and Dunn, A. R., Mice lacking both macrophage- and granulocyte-macrophage colony-stimulating factor have macrophages and coexistent osteopetrosis and severe lung disease, Blood, 84(1), 27, 1994.
-
(1994)
Blood
, vol.84
, Issue.1
, pp. 27
-
-
Lieschke, G.J.1
Stanley, E.2
Grail, D.3
Hodgson, G.4
Sinickas, V.5
Gall, J.A.6
Sinclair, R.A.7
Dunn, A.R.8
-
43
-
-
0028920074
-
Mice deficient for the IL-3/GM-CSF/IL-5 beta-c receptor exhibit lung pathology and impaired immune response, while beta-IL-3 receptor deficient mice are normal
-
Nishinakamura, R., Nakayama, N., Hirabazashi, Y., Araai, K., Miyajima, A., and Murray, R., Mice deficient for the IL-3/GM-CSF/IL-5 beta-c receptor exhibit lung pathology and impaired immune response, while beta-IL-3 receptor deficient mice are normal, Immunity, 2, 211, 1995.
-
(1995)
Immunity
, vol.2
, pp. 211
-
-
Nishinakamura, R.1
Nakayama, N.2
Hirabazashi, Y.3
Araai, K.4
Miyajima, A.5
Murray, R.6
-
44
-
-
0028302409
-
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand
-
de-Sauvage, F. J., Hass, P. E., Spencer, S. D., Malloy, B. E., Gurney, A. L., Spencer, S. A., Darbonne, W. C., Henzel, W. J., Wong, S. C., Kuang, W. J., et al., Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand [see comments], Nature (London), 369(6481), 533, 1994.
-
(1994)
Nature (London)
, vol.369
, Issue.6481
, pp. 533
-
-
De-Sauvage, F.J.1
Hass, P.E.2
Spencer, S.D.3
Malloy, B.E.4
Gurney, A.L.5
Spencer, S.A.6
Darbonne, W.C.7
Henzel, W.J.8
Wong, S.C.9
Kuang, W.J.10
-
45
-
-
0029069565
-
Matrix metalloproteinases and processing of pro-TNF-alpha
-
Gearing, A. J., Beckett, P., Christodoulou, M., Churchill, M., Clements, J. M., Crimmin, M., Davidson, A. H., Drummond, A. H., Galloway, W. A., Gilbert, R., et al., Matrix metalloproteinases and processing of pro-TNF-alpha, J. Leukocyte Biol., 57(5), 774, 1995.
-
(1995)
J. Leukocyte Biol.
, vol.57
, Issue.5
, pp. 774
-
-
Gearing, A.J.1
Beckett, P.2
Christodoulou, M.3
Churchill, M.4
Clements, J.M.5
Crimmin, M.6
Davidson, A.H.7
Drummond, A.H.8
Galloway, W.A.9
Gilbert, R.10
-
46
-
-
0027415109
-
Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface
-
Browning, J. L., Ngam-Ek, A., Lawton, P., DeMarinis, J., Tizard, R., Chow, E. P., Hession, C., O'Brine-Greco, B., Foley, S.F., and Ware, C. F., Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface, Cell, 72(6), 847, 1993.
-
(1993)
Cell
, vol.72
, Issue.6
, pp. 847
-
-
Browning, J.L.1
Ngam-Ek, A.2
Lawton, P.3
DeMarinis, J.4
Tizard, R.5
Chow, E.P.6
Hession, C.7
O'Brine-Greco, B.8
Foley, S.F.9
Ware, C.F.10
-
47
-
-
0028179614
-
A lymphotoxin-beta-specific receptor
-
Crowe, P. D., VanArsdale, T. L., Walter, B. N., Ware, C. F., Hession, C., Ehrenfels, B., Browning, J. L., Din, W. S., Goodwin, R. G., and Smith, C. A., A lymphotoxin-beta-specific receptor [see comments], Science, 264(5159), 707, 1994.
-
(1994)
Science
, vol.264
, Issue.5159
, pp. 707
-
-
Crowe, P.D.1
VanArsdale, T.L.2
Walter, B.N.3
Ware, C.F.4
Hession, C.5
Ehrenfels, B.6
Browning, J.L.7
Din, W.S.8
Goodwin, R.G.9
Smith, C.A.10
-
48
-
-
0027327619
-
Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
-
Rothe, J., Lesslauer, W., Lotscher, H., Lang, Y., Koebel, P., Kontgen, F., Althage, A., Zinkernagel, R., Steinmetz, M., and Bluethmann, H., Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes, Nature (London), 364(6440), 798, 1993.
-
(1993)
Nature (London)
, vol.364
, Issue.6440
, pp. 798
-
-
Rothe, J.1
Lesslauer, W.2
Lotscher, H.3
Lang, Y.4
Koebel, P.5
Kontgen, F.6
Althage, A.7
Zinkernagel, R.8
Steinmetz, M.9
Bluethmann, H.10
-
49
-
-
0027297663
-
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
-
Pfeffer, K., Matsuyama, T., Kundig, T. M., Wakeham, A., Kishihara, K., Shahinian, A., Wiegmann, K., Ohashi, P. S., Kronke, M., and Mak, T. W., Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection, Cell, 73(3), 457, 1993.
-
(1993)
Cell
, vol.73
, Issue.3
, pp. 457
-
-
Pfeffer, K.1
Matsuyama, T.2
Kundig, T.M.3
Wakeham, A.4
Kishihara, K.5
Shahinian, A.6
Wiegmann, K.7
Ohashi, P.S.8
Kronke, M.9
Mak, T.W.10
-
50
-
-
0000682810
-
Differentiation of follicular dendritic cells and full antibody responses require TNF receptor-1 signalling
-
in press
-
Le Hir, M., Bluethmann, H., Kosco-Vilbois, M. H., Muller, M., di Padova, F., Moore, M., Ryffel, B., and Eugster, H. P., Differentiation of follicular dendritic cells and full antibody responses require TNF receptor-1 signalling, J. Exp. Med., in press, 1996.
-
(1996)
J. Exp. Med.
-
-
Le Hir, M.1
Bluethmann, H.2
Kosco-Vilbois, M.H.3
Muller, M.4
Di Padova, F.5
Moore, M.6
Ryffel, B.7
Eugster, H.P.8
-
51
-
-
0028063303
-
Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice
-
Erickson, S. L., de Sauvage, F. J., Kikly, K., Carver-Moore, K., Pitts-Meek, S., Gillett, N., Sheehan, K. C., Schreiber, R. D., Goeddel, D. V., and Moore, M. W., Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice, Nature (London), 372(6506), 560, 1994.
-
(1994)
Nature (London)
, vol.372
, Issue.6506
, pp. 560
-
-
Erickson, S.L.1
De Sauvage, F.J.2
Kikly, K.3
Carver-Moore, K.4
Pitts-Meek, S.5
Gillett, N.6
Sheehan, K.C.7
Schreiber, R.D.8
Goeddel, D.V.9
Moore, M.W.10
-
52
-
-
0028277665
-
Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin
-
De Togni, P., Goellner, J., Ruddle, N. H., Streeter, P. R., Fick, A., Mariathasan, S., Smith, S. C., Carlson, R., Shornick, L. P., Strauss-Schoenberger, J., et al., Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin [see comments], Science, 264(5159), 703, 1994.
-
(1994)
Science
, vol.264
, Issue.5159
, pp. 703
-
-
De Togni, P.1
Goellner, J.2
Ruddle, N.H.3
Streeter, P.R.4
Fick, A.5
Mariathasan, S.6
Smith, S.C.7
Carlson, R.8
Shornick, L.P.9
Strauss-Schoenberger, J.10
-
53
-
-
0028979065
-
Lymphotoxin-a deficient mice
-
Banks, T. A., Rouse, B. T., Kerley, M. K., Blair, P. J., Godfrey, V. L., Kuklin, N. K., Bouley, D. M., Thomas, J., Kanangat, S., and Mucenski, M. L., Lymphotoxin-a deficient mice, J. Immunol., 155: 1685, 1995.
-
(1995)
J. Immunol.
, vol.155
, pp. 1685
-
-
Banks, T.A.1
Rouse, B.T.2
Kerley, M.K.3
Blair, P.J.4
Godfrey, V.L.5
Kuklin, N.K.6
Bouley, D.M.7
Thomas, J.8
Kanangat, S.9
Mucenski, M.L.10
-
54
-
-
0029991923
-
Role of lymphotoxin and type I TNF receptor in the formation of germinal centers
-
Matsumoto, M., Nariathasan, S., Hahm, M. H., Peschon, J. J., and Chaplin, D. D., Role of lymphotoxin and type I TNF receptor in the formation of germinal centers, Science, 271, 1289, 1996.
-
(1996)
Science
, vol.271
, pp. 1289
-
-
Matsumoto, M.1
Nariathasan, S.2
Hahm, M.H.3
Peschon, J.J.4
Chaplin, D.D.5
-
55
-
-
13344295091
-
Multiple immune abormalities in TNF and LTa double deficient mice
-
Eugster, H. P., Muller, M., Karrer, U., Car, B. D., Schnyder, B., Eng, V. M., Woerly, G., Di Padova, F., Aguet, M., Zinkernagel, R., Bluethmann, H., and Ryffel, B., Multiple immune abormalities in TNF and LTa double deficient mice, It Immunol., 8(1), 23, 1996.
-
(1996)
It Immunol.
, vol.8
, Issue.1
, pp. 23
-
-
Eugster, H.P.1
Muller, M.2
Karrer, U.3
Car, B.D.4
Schnyder, B.5
Eng, V.M.6
Woerly, G.7
Di Padova, F.8
Aguet, M.9
Zinkernagel, R.10
Bluethmann, H.11
Ryffel, B.12
-
56
-
-
0029751937
-
Correction and transfer of immunodeficiency of TMF-LT deficiency by bone marrow transplantation
-
Muller, M., Eugster, H. P., Le Hir, M., Shakhov, A., Di Padova, F., Maurer, C., Quesniaux, V. J. F., and Ryffel, B., Correction and transfer of immunodeficiency of TMF-LT deficiency by bone marrow transplantation, Mol. Med., 2, 247, 1996.
-
(1996)
Mol. Med.
, vol.2
, pp. 247
-
-
Muller, M.1
Eugster, H.P.2
Le Hir, M.3
Shakhov, A.4
Di Padova, F.5
Maurer, C.6
Quesniaux, V.J.F.7
Ryffel, B.8
-
57
-
-
0028135424
-
Humoral immune responses in CD40 ligand-deficient mice
-
Renshaw, B. R., Fanslow, W. R., Armitage, R. J., Campbell, K. A., Liggitt, D., Wright, B., Davison, B. L., and Maliszewski, C. R., Humoral immune responses in CD40 ligand-deficient mice, J. Exp. Med., 180(5), 1889, 1994.
-
(1994)
J. Exp. Med.
, vol.180
, Issue.5
, pp. 1889
-
-
Renshaw, B.R.1
Fanslow, W.R.2
Armitage, R.J.3
Campbell, K.A.4
Liggitt, D.5
Wright, B.6
Davison, B.L.7
Maliszewski, C.R.8
-
58
-
-
0027960913
-
CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation
-
Castigli, E., Alt, F. W., Davidson, L., Bottaro, A., Mizoguchi, E., Bhan, A. K., and Geha, R. S., CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation, Proc. Natl. Acad. Sci. U. S. A., 91(25), 12135, 1994.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, Issue.25
, pp. 12135
-
-
Castigli, E.1
Alt, F.W.2
Davidson, L.3
Bottaro, A.4
Mizoguchi, E.5
Bhan, A.K.6
Geha, R.S.7
-
59
-
-
0002622397
-
Central role of CD40 and its ligand in B lymphocyte responses to T-dependent antigens
-
Gordon, J., Katira, A., Holder, M., MacDonald, I., and Pound, J., Central role of CD40 and its ligand in B lymphocyte responses to T-dependent antigens, Cell. Mol. Biol., 1(1), 1, 1994.
-
(1994)
Cell. Mol. Biol.
, vol.1
, Issue.1
, pp. 1
-
-
Gordon, J.1
Katira, A.2
Holder, M.3
MacDonald, I.4
Pound, J.5
-
60
-
-
0028223847
-
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
-
Takahashi, T., Tanaka, M., Brannan, C. I., Jenkins, N. A., Copeland, N. G., Suda, T., and Nagata, S., Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand, Cell, 76(6), 969, 1994.
-
(1994)
Cell
, vol.76
, Issue.6
, pp. 969
-
-
Takahashi, T.1
Tanaka, M.2
Brannan, C.I.3
Jenkins, N.A.4
Copeland, N.G.5
Suda, T.6
Nagata, S.7
-
61
-
-
0029157723
-
Resistance to fever induction and impaired acute-phase response in interleukin-1b-deficient mice
-
Zheng, H., Fletcher, D., Kozak, W., Hofmann, K. J. J., Tocci, M. J., and Ploegh, V. D., Resistance to fever induction and impaired acute-phase response in interleukin-1b-deficient mice, Immunity, 3, 9, 1995.
-
(1995)
Immunity
, vol.3
, pp. 9
-
-
Zheng, H.1
Fletcher, D.2
Kozak, W.3
Hofmann, K.J.J.4
Tocci, M.J.5
Ploegh, V.D.6
-
62
-
-
0028920863
-
Altered cytokine export and apoptosis in mice deficient in interleukin-1beta converting enzyme
-
Kuida, K., Lippke, J., Ku, G., Harding, M., Livingston, D., and Su, M., Altered cytokine export and apoptosis in mice deficient in interleukin-1beta converting enzyme, Science, 267, 2000, 1995.
-
(1995)
Science
, vol.267
, pp. 2000
-
-
Kuida, K.1
Lippke, J.2
Ku, G.3
Harding, M.4
Livingston, D.5
Su, M.6
-
63
-
-
0028984948
-
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
-
Li, P., Allen, H., Banerjee, S., Franklin, S., Herzog, L., Johnston, C., McDowell, J., Paskind, M., Rodman, L., Salfeld, J. et al., Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock, Cell, 80(3), 401, 1995.
-
(1995)
Cell
, vol.80
, Issue.3
, pp. 401
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
Johnston, C.6
McDowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
-
64
-
-
0027724228
-
Transforming growth factor-beta 1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease
-
Kulkarni, A. B. and Karlsson, S., Transforming growth factor-beta 1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease, Am. J. Pathol., 143(1), 3, 1993.
-
(1993)
Am. J. Pathol.
, vol.143
, Issue.1
, pp. 3
-
-
Kulkarni, A.B.1
Karlsson, S.2
-
65
-
-
0026799402
-
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
-
Shull, M. M., Ormsby, I., Kier, A. B., Pawlowski, S., Diebold, R. J., Yin, M., Allen, R., Sidman, C., Proetzel, G., Calvin, D., et al., Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease, Nature (London), 359(6397), 693, 1992.
-
(1992)
Nature (London)
, vol.359
, Issue.6397
, pp. 693
-
-
Shull, M.M.1
Ormsby, I.2
Kier, A.B.3
Pawlowski, S.4
Diebold, R.J.5
Yin, M.6
Allen, R.7
Sidman, C.8
Proetzel, G.9
Calvin, D.10
-
66
-
-
0029035476
-
Altered immune response in mice lacking inducible nitric oxide synthase
-
Wei, X., Charles, I., Smith, A., Ure, J., and Feng, G., Altered immune response in mice lacking inducible nitric oxide synthase, Nature (London), 375, 408, 1995.
-
(1995)
Nature (London)
, vol.375
, pp. 408
-
-
Wei, X.1
Charles, I.2
Smith, A.3
Ure, J.4
Feng, G.5
-
67
-
-
0028999596
-
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
-
MacMicking, J., Nathan, D., Horn, D., Chartrain, N., and Fletscher, D., Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase, Cell, 81, 641, 1995.
-
(1995)
Cell
, vol.81
, pp. 641
-
-
MacMicking, J.1
Nathan, D.2
Horn, D.3
Chartrain, N.4
Fletscher, D.5
-
68
-
-
0027769462
-
Targeted disruption of the neuronal nitric oxide synthase gene
-
Huang, P. L., Dawson, T. M., Bredt, D. S., Snyder, S. H., and Fishman, M. C., Targeted disruption of the neuronal nitric oxide synthase gene, Cell, 75(7), 1273, 1993.
-
(1993)
Cell
, vol.75
, Issue.7
, pp. 1273
-
-
Huang, P.L.1
Dawson, T.M.2
Bredt, D.S.3
Snyder, S.H.4
Fishman, M.C.5
-
69
-
-
0027945658
-
Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase
-
Huang, Z., Huang, P. L., Panahian, N., Dalkara, T., Fishman, M. C., and Moskowitz, M. A., Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase, Science, 265(5180), 1883, 1994.
-
(1994)
Science
, vol.265
, Issue.5180
, pp. 1883
-
-
Huang, Z.1
Huang, P.L.2
Panahian, N.3
Dalkara, T.4
Fishman, M.C.5
Moskowitz, M.A.6
-
70
-
-
0026768292
-
Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor
-
Stewart, C. L., Kaspar, P., Brunet, L. J., Bhatt, H., Gadi, I., Kontgen, F., and Abbondanzo, S. J., Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor [see comments], Nature (London), 359(6390), 76, 1992.
-
(1992)
Nature (London)
, vol.359
, Issue.6390
, pp. 76
-
-
Stewart, C.L.1
Kaspar, P.2
Brunet, L.J.3
Bhatt, H.4
Gadi, I.5
Kontgen, F.6
Abbondanzo, S.J.7
-
71
-
-
0027233526
-
Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation
-
Escary, J. L., Perreau, J., Dumenil, D., Ezine, S., and Brulet, P., Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation, Nature (London), 363(6427), 361, 1993.
-
(1993)
Nature (London)
, vol.363
, Issue.6427
, pp. 361
-
-
Escary, J.L.1
Perreau, J.2
Dumenil, D.3
Ezine, S.4
Brulet, P.5
-
72
-
-
0027982876
-
Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
-
Springer, T. A., Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm, Cell, 76(2), 301, 1994.
-
(1994)
Cell
, vol.76
, Issue.2
, pp. 301
-
-
Springer, T.A.1
-
73
-
-
0027209421
-
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
-
Mayadas, T. N., Johnson, R. C., Rayburn, H., Hynes, R. O., and Wagner, D. D., Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice, Cell, 74(3), 541, 1993.
-
(1993)
Cell
, vol.74
, Issue.3
, pp. 541
-
-
Mayadas, T.N.1
Johnson, R.C.2
Rayburn, H.3
Hynes, R.O.4
Wagner, D.D.5
-
74
-
-
0029034077
-
Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-Selectin-deficient mice
-
Subramaniam, M., Saffaripour, S., Watson, S., Mayadas, T., and Hynes, R., Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-Selectin-deficient mice, J. Exp. Med., 181, 2277, 1995.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 2277
-
-
Subramaniam, M.1
Saffaripour, S.2
Watson, S.3
Mayadas, T.4
Hynes, R.5
-
75
-
-
0029042710
-
L-Selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites
-
Tedder, T., Steeber, D., and Pizcueta, P., L-Selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites, J. Exp. Med., 181, 2259, 1995.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 2259
-
-
Tedder, T.1
Steeber, D.2
Pizcueta, P.3
-
76
-
-
0028067339
-
Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog
-
Cacalano, G., Lee, J., Kikly, K., Ryan, A. M., Pitts-Meek, S., Hultgren, B., Wood, W. I., and Moore, M. W., Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog, Science, 265(5172), 682, 1994.
-
(1994)
Science
, vol.265
, Issue.5172
, pp. 682
-
-
Cacalano, G.1
Lee, J.2
Kikly, K.3
Ryan, A.M.4
Pitts-Meek, S.5
Hultgren, B.6
Wood, W.I.7
Moore, M.W.8
-
77
-
-
0028336730
-
Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice
-
Xu, H., Gonzalo, J. A., St. Pierre, Y., Williams, I. R., Kupper, T. S., Cotran, R. S., Springer, T. A., and Gutierrez-Ramos, J. C., Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice, J. Exp. Med., 180(1), 95, 1994.
-
(1994)
J. Exp. Med.
, vol.180
, Issue.1
, pp. 95
-
-
Xu, H.1
Gonzalo, J.A.2
St. Pierre, Y.3
Williams, I.R.4
Kupper, T.S.5
Cotran, R.S.6
Springer, T.A.7
Gutierrez-Ramos, J.C.8
-
78
-
-
0028956614
-
P-Selectin/ICAM-1 double mutant mice: Acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli
-
Bullard, D., Qin, L., Lorenzo, I., Quinlin, W., and Doyle, W., P-Selectin/ICAM-1 double mutant mice: acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli, J. Clin. Invest., 95, 1782-1995.
-
J. Clin. Invest.
, vol.95
, pp. 1782-1995
-
-
Bullard, D.1
Qin, L.2
Lorenzo, I.3
Quinlin, W.4
Doyle, W.5
-
79
-
-
0029060861
-
Male-female differences in fertility and blood pressure in ACE-deficient mice
-
Krege, J., John, S., Langenbach, L., Hodgin, J., Hagaman, J., and Bachman, E., Male-female differences in fertility and blood pressure in ACE-deficient mice, Nature (London), 375, 146, 1995.
-
(1995)
Nature (London)
, vol.375
, pp. 146
-
-
Krege, J.1
John, S.2
Langenbach, L.3
Hodgin, J.4
Hagaman, J.5
Bachman, E.6
-
80
-
-
0028112934
-
Tissue distribution of the human MDR3 P-glycoprotein
-
Smit, J. J., Schinkel, A. H., Mol, C. A., Majoor, D., Mooi, W. J., Jongsma, A. P., Lincke, C. R., and Borst, P., Tissue distribution of the human MDR3 P-glycoprotein [see comments], Lab. Invest., 71(5), 638, 1994.
-
(1994)
Lab. Invest.
, vol.71
, Issue.5
, pp. 638
-
-
Smit, J.J.1
Schinkel, A.H.2
Mol, C.A.3
Majoor, D.4
Mooi, W.J.5
Jongsma, A.P.6
Lincke, C.R.7
Borst, P.8
-
81
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
Schinkel, A. H., Smit, J. J., van Tellingen, O., Beijnen, J. H., Wagenaar, E., van Deemter, L., Mol, C. A., van derValk, M. A., Robanus-Maandag, E. C., te Riele, H. P., et al., Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs, Cell, 77(4), 491, 1994.
-
(1994)
Cell
, vol.77
, Issue.4
, pp. 491
-
-
Schinkel, A.H.1
Smit, J.J.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.7
Van DerValk, M.A.8
Robanus-Maandag, E.C.9
Te Riele, H.P.10
-
82
-
-
0028899952
-
Scatter factor/hepatocyte growth factor is essential for liver development
-
Schmidt, C., Bladt, F., Goedecke, S., Brinkmann, V., Zschiesche, W., Sharpe, M., Gherardi, E., and Birchmeier, C., Scatter factor/hepatocyte growth factor is essential for liver development, Nature (London), 373(6516), 699, 1995.
-
(1995)
Nature (London)
, vol.373
, Issue.6516
, pp. 699
-
-
Schmidt, C.1
Bladt, F.2
Goedecke, S.3
Brinkmann, V.4
Zschiesche, W.5
Sharpe, M.6
Gherardi, E.7
Birchmeier, C.8
-
83
-
-
0028911690
-
Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor
-
Uehara, Y., Minowa, O., Mori, C., Shiota, K., Kuno, J., Noda, T., and Kitamura, N., Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor, Nature (London), 373(6516), 702, 1995.
-
(1995)
Nature (London)
, vol.373
, Issue.6516
, pp. 702
-
-
Uehara, Y.1
Minowa, O.2
Mori, C.3
Shiota, K.4
Kuno, J.5
Noda, T.6
Kitamura, N.7
-
84
-
-
0028032894
-
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
-
Tamemoto, H., Kadowaki, T., Tobe, K., Yagi, T., Sakura, H., Hayakawa, T., Terauchi, Y., Ueki, K., Kaburagi, Y., Satoh, S., et al., Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1 [see comments], Nature (London), 372(6502), 182, 1994.
-
(1994)
Nature (London)
, vol.372
, Issue.6502
, pp. 182
-
-
Tamemoto, H.1
Kadowaki, T.2
Tobe, K.3
Yagi, T.4
Sakura, H.5
Hayakawa, T.6
Terauchi, Y.7
Ueki, K.8
Kaburagi, Y.9
Satoh, S.10
-
85
-
-
0028032895
-
Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene
-
Araki, E., Lipes, M. A., Patti, M. E., Bruning, J. C., Haag, B. R., Johnson, R. S., and Kahn, C. R., Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene [see comments], Nature (London), 372(6502), 186, 1994.
-
(1994)
Nature (London)
, vol.372
, Issue.6502
, pp. 186
-
-
Araki, E.1
Lipes, M.A.2
Patti, M.E.3
Bruning, J.C.4
Haag, B.R.5
Johnson, R.S.6
Kahn, C.R.7
-
86
-
-
0026592806
-
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
-
Zhang, S. H., Reddick, R. L., Piedrahita, J. A., and Maeda, N., Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E, Science, 258(5081), 468, 1992.
-
(1992)
Science
, vol.258
, Issue.5081
, pp. 468
-
-
Zhang, S.H.1
Reddick, R.L.2
Piedrahita, J.A.3
Maeda, N.4
-
87
-
-
0027258140
-
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
-
Ishibashi, S., Brown, M.S., Goldstein, J.L., Gerard, R. D., Hammer, R. E., and Herz, J., Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery [see comments], J. Clin. Invest., 92(2), 883, 1993.
-
(1993)
J. Clin. Invest.
, vol.92
, Issue.2
, pp. 883
-
-
Ishibashi, S.1
Brown, M.S.2
Goldstein, J.L.3
Gerard, R.D.4
Hammer, R.E.5
Herz, J.6
-
88
-
-
0027945466
-
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene
-
Chen, X. S., Sheller, J. R., Johnson, E. N., and Funk, C. D., Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene, Nature (London), 372(6502), 179, 1994.
-
(1994)
Nature (London)
, vol.372
, Issue.6502
, pp. 179
-
-
Chen, X.S.1
Sheller, J.R.2
Johnson, E.N.3
Funk, C.D.4
-
89
-
-
0028589332
-
Altered inflammatory responses in leukotriene-deficient mice
-
Goulet, J. L., Snouwaert, J. N., Latour, A. M., Coffman, T. M., and Koller, B. H., Altered inflammatory responses in leukotriene-deficient mice, Proc. Natl. Acad. Sci. U. S. A., 91(26), 12852, 1994.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, Issue.26
, pp. 12852
-
-
Goulet, J.L.1
Snouwaert, J.N.2
Latour, A.M.3
Coffman, T.M.4
Koller, B.H.5
-
90
-
-
0028807498
-
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
-
Morham, S. G., Langenbach, R., Loftin, C. D., Tiano, H. F., Vouloumanos, N., Jennette, J. C., Mahler, J. F., Kluckman, K. D., Ledford, A., Lee, C. A., et al., Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse, Cell, 83(3), 473, 1995.
-
(1995)
Cell, 83
, Issue.3
, pp. 473
-
-
Morham, S.G.1
Langenbach, R.2
Loftin, C.D.3
Tiano, H.F.4
Vouloumanos, N.5
Jennette, J.C.6
Mahler, J.F.7
Kluckman, K.D.8
Ledford, A.9
Lee, C.A.10
-
91
-
-
0028843881
-
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
-
Langenbach, R., Morham, S. G., Tiano, H. F., Loftin, C. D., Ghanayem, B. I., Chulada, P. C., Mahler, J. F., Lee, C. A., Goulding, E. H., Kluckman, K. D., et al., Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration, Cell, 83(3), 483, 1995.
-
(1995)
Cell
, vol.83
, Issue.3
, pp. 483
-
-
Langenbach, R.1
Morham, S.G.2
Tiano, H.F.3
Loftin, C.D.4
Ghanayem, B.I.5
Chulada, P.C.6
Mahler, J.F.7
Lee, C.A.8
Goulding, E.H.9
Kluckman, K.D.10
-
92
-
-
0028818913
-
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
-
Dinchuk, J. E., Car, B. D., Focht, R. J., Johnston, J. J., Jaffee, B. D., Covington, M. B., Contel, N. R., Eng, V. M., Collins, R. J., Czerniak, P. M., et al., Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II, Nature (London), 378(6555), 406, 1995.
-
(1995)
Nature (London)
, vol.378
, Issue.6555
, pp. 406
-
-
Dinchuk, J.E.1
Car, B.D.2
Focht, R.J.3
Johnston, J.J.4
Jaffee, B.D.5
Covington, M.B.6
Contel, N.R.7
Eng, V.M.8
Collins, R.J.9
Czerniak, P.M.10
-
93
-
-
0027236534
-
Osteoblasts are target cells for transformation in c-fos transgenic mice
-
Grigoriadis, A. E., Schellander, K., Wang, Z. Q., and Wagner, E. F., Osteoblasts are target cells for transformation in c-fos transgenic mice, J. Cell. Biol., 122(3), 685, 1993.
-
(1993)
J. Cell. Biol.
, vol.122
, Issue.3
, pp. 685
-
-
Grigoriadis, A.E.1
Schellander, K.2
Wang, Z.Q.3
Wagner, E.F.4
-
94
-
-
0027070472
-
Bone and haematopoietic defects in mice lacking c-fos
-
Wang, Z. Q., Ovitt, C., Grigoriadis, A. E., Mohle-Steinlein, U., Ruther, U., and Wagner, E. F., Bone and haematopoietic defects in mice lacking c-fos, Nature (London), 360(6406), 741, 1992.
-
(1992)
Nature (London)
, vol.360
, Issue.6406
, pp. 741
-
-
Wang, Z.Q.1
Ovitt, C.2
Grigoriadis, A.E.3
Mohle-Steinlein, U.4
Ruther, U.5
Wagner, E.F.6
-
95
-
-
0027427492
-
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
-
Veis, D. J., Sorenson, C. M., Shutter, J. R., and Korsmeyer, S. J., Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair, Cell, 75(2), 229, 1993.
-
(1993)
Cell
, vol.75
, Issue.2
, pp. 229
-
-
Veis, D.J.1
Sorenson, C.M.2
Shutter, J.R.3
Korsmeyer, S.J.4
-
96
-
-
0026561121
-
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
-
Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C., Jr., Butel, J. S., and Bradley, A., Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours, Nature (London), 356(6366), 215, 1992.
-
(1992)
Nature (London)
, vol.356
, Issue.6366
, pp. 215
-
-
Donehower, L.A.1
Harvey, M.2
Slagle, B.L.3
McArthur, M.J.4
Montgomery Jr., C.5
Butel, J.S.6
Bradley, A.7
-
97
-
-
0027203921
-
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors
-
Kemp, C. J., Donehower, L. A., Bradley, A., and Balmain, A., Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors, Cell, 74(5), 813, 1993.
-
(1993)
Cell
, vol.74
, Issue.5
, pp. 813
-
-
Kemp, C.J.1
Donehower, L.A.2
Bradley, A.3
Balmain, A.4
-
98
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks, T., Fazeli, A., Schmitt, E. M., Bronson, R. T., Goodell, M. A., and Weinberg, R. A., Effects of an Rb mutation in the mouse [see comments], Nature (London), 359(6393), 295, 1992.
-
(1992)
Nature (London)
, vol.359
, Issue.6393
, pp. 295
-
-
Jacks, T.1
Fazeli, A.2
Schmitt, E.M.3
Bronson, R.T.4
Goodell, M.A.5
Weinberg, R.A.6
-
99
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
Lee, E. Y., Chang, C. Y., Hu, N., Wang, Y. C., Lai, C. C., Herrup, K., Lee, W. H., and Bradley, A., Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis [see comments], Nature (London), 359(6393), 288, 1992.
-
(1992)
Nature (London)
, vol.359
, Issue.6393
, pp. 288
-
-
Lee, E.Y.1
Chang, C.Y.2
Hu, N.3
Wang, Y.C.4
Lai, C.C.5
Herrup, K.6
Lee, W.H.7
Bradley, A.8
-
100
-
-
0027729893
-
Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor alpha chain gene
-
Dombrowicz, D., Flamand, V., Brigman, K. K., Koller, B. H., and Kinet, J. P., Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor alpha chain gene, Cell, 75(5), 969, 1993.
-
(1993)
Cell
, vol.75
, Issue.5
, pp. 969
-
-
Dombrowicz, D.1
Flamand, V.2
Brigman, K.K.3
Koller, B.H.4
Kinet, J.P.5
-
101
-
-
0028042424
-
FcR gamma chain deletion results in pleiotrophic effector cell defects
-
Takai, T., Li, M., Sylvestre, D., Clynes, R., and Ravetch, J. V., FcR gamma chain deletion results in pleiotrophic effector cell defects, Cell, 76(3), 519, 1994.
-
(1994)
Cell
, vol.76
, Issue.3
, pp. 519
-
-
Takai, T.1
Li, M.2
Sylvestre, D.3
Clynes, R.4
Ravetch, J.V.5
-
102
-
-
0028284181
-
Negative feedback regulation of IgE synthesis by murine CD23
-
Yu, P., Kosco, V. M., Richards, M., Kohler, G., and Lamers, M. C., Negative feedback regulation of IgE synthesis by murine CD23, Nature (London), 369(6483), 753, 1994.
-
(1994)
Nature (London)
, vol.369
, Issue.6483
, pp. 753
-
-
Yu, P.1
Kosco, V.M.2
Richards, M.3
Kohler, G.4
Lamers, M.C.5
-
103
-
-
0028071646
-
Active anaphylaxis in IgE-deficient mice
-
Oettgen, H. C., Martin, T. R., Wynshaw-Boris, A., Deng, C., Drazen, J. M., and Leder, P., Active anaphylaxis in IgE-deficient mice, Nature (London), 370(6488), 367, 1994.
-
(1994)
Nature (London)
, vol.370
, Issue.6488
, pp. 367
-
-
Oettgen, H.C.1
Martin, T.R.2
Wynshaw-Boris, A.3
Deng, C.4
Drazen, J.M.5
Leder, P.6
-
104
-
-
0028244816
-
Tumor necrosis factor: A pleiotropic cytokine and therapeutic target
-
Tracey, K. J. and Cerami, A., Tumor necrosis factor: a pleiotropic cytokine and therapeutic target, Annu. Rev. Med., 45, 491, 1994.
-
(1994)
Annu. Rev. Med.
, vol.45
, pp. 491
-
-
Tracey, K.J.1
Cerami, A.2
-
105
-
-
0029131488
-
Transgenic mice expressing high levels of soluble TNF-RI fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections, Eur
-
Garcia, I., Miyazaki, Y., Araki, K., Araki, M., Lucas, R., Grau, G. E., Milon, G., Belkaid, Y., Montixi, C., Lesslauer, W., et al., Transgenic mice expressing high levels of soluble TNF-RI fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections, Eur. J. Immunol., 25(8), 2401, 1995.
-
(1995)
J. Immunol.
, vol.25
, Issue.8
, pp. 2401
-
-
Garcia, I.1
Miyazaki, Y.2
Araki, K.3
Araki, M.4
Lucas, R.5
Grau, G.E.6
Milon, G.7
Belkaid, Y.8
Montixi, C.9
Lesslauer, W.10
-
106
-
-
0028343059
-
Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors
-
Novogrodsky, A., Vanichkin, A., Patya, M., Gazit, A., Osherov, N., and Levitzki, A., Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors, Science, 264(5163), 1319, 1994.
-
(1994)
Science
, vol.264
, Issue.5163
, pp. 1319
-
-
Novogrodsky, A.1
Vanichkin, A.2
Patya, M.3
Gazit, A.4
Osherov, N.5
Levitzki, A.6
-
107
-
-
0028222122
-
Interferon gamma receptor deficient mice are resistant to endotoxic shock
-
Car, B. D., Eng, V. M., Schnyder, B., Ozmen, L., Huang, S., Gallay, P., Heumann, D., Aguet, M., and Ryffel, B., Interferon gamma receptor deficient mice are resistant to endotoxic shock, J. Exp. Med., 179(5), 1437, 1994.
-
(1994)
J. Exp. Med.
, vol.179
, Issue.5
, pp. 1437
-
-
Car, B.D.1
Eng, V.M.2
Schnyder, B.3
Ozmen, L.4
Huang, S.5
Gallay, P.6
Heumann, D.7
Aguet, M.8
Ryffel, B.9
-
108
-
-
0028095919
-
The acute phase response
-
Baumann, H. and Gauldie, J., The acute phase response, Immunol. Today, 15(2), 74, 1994.
-
(1994)
Immunol. Today
, vol.15
, Issue.2
, pp. 74
-
-
Baumann, H.1
Gauldie, J.2
-
109
-
-
85176674445
-
Role of interferon gamma in interleukin 12 induced pathology
-
in press
-
Car, B. D., Schnyder, B., Aguet, M., and Ryffel, B., Role of interferon gamma in interleukin 12 induced pathology, Am. J. Pathol., in press, 1995.
-
(1995)
Am. J. Pathol.
-
-
Car, B.D.1
Schnyder, B.2
Aguet, M.3
Ryffel, B.4
-
110
-
-
0028916621
-
The stimuatory effects of interleukin-12 on hematopoiesis are antagonized by IL-12-induced interferon gamma in vivo
-
Eng, V. M., Car, B. D., Schnyder, B., Lorenz, M., Lugli, S., Anderson, T. A., Huang, S., Aguet, M., Ryffel, B., and Quesniaux, V. F., The stimuatory effects of interleukin-12 on hematopoiesis are antagonized by IL-12-induced interferon gamma in vivo, J. Exp. Med., 181(5), 1893, 1995.
-
(1995)
J. Exp. Med.
, vol.181
, Issue.5
, pp. 1893
-
-
Eng, V.M.1
Car, B.D.2
Schnyder, B.3
Lorenz, M.4
Lugli, S.5
Anderson, T.A.6
Huang, S.7
Aguet, M.8
Ryffel, B.9
Quesniaux, V.F.10
-
111
-
-
0029000839
-
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor
-
Fernandez-Salguero, P., Pineau, T., Hubert, D., McPhail, T., and Lee, S., Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor, Science, 268, 722, 1995.
-
(1995)
Science
, vol.268
, pp. 722
-
-
Fernandez-Salguero, P.1
Pineau, T.2
Hubert, D.3
McPhail, T.4
Lee, S.5
-
112
-
-
0028846647
-
In situ detection of cyclosporin A: Evidence for nuclear localization of cyclosporine and cyclophilins
-
Le Hir, M., Su, Q., Weber, L., Woerly, G., Granelli Piperno, A., and Ryffel, B., In situ detection of cyclosporin A: evidence for nuclear localization of cyclosporine and cyclophilins, Lab. Invest., 73(5), 727, 1995.
-
(1995)
Lab. Invest.
, vol.73
, Issue.5
, pp. 727
-
-
Le Hir, M.1
Su, Q.2
Weber, L.3
Woerly, G.4
Granelli Piperno, A.5
Ryffel, B.6
-
113
-
-
0027184839
-
Cyclosporin binding proteins. Identification, distribution, function and relation to FK binding proteins
-
Ryffel, B., Cyclosporin binding proteins. Identification, distribution, function and relation to FK binding proteins, Biochem. Pharmacol., 46(1), 1, 1993.
-
(1993)
Biochem. Pharmacol.
, vol.46
, Issue.1
, pp. 1
-
-
Ryffel, B.1
-
114
-
-
85036445802
-
-
personal communication
-
Kopf, M., personal communication.
-
-
-
Kopf, M.1
-
115
-
-
85036439879
-
-
in preparation
-
Magram, et al., in preparation.
-
-
-
Magram1
-
116
-
-
85036448896
-
-
in preparation
-
Grau, G. E., et al., in preparation.
-
-
-
Grau, G.E.1
-
117
-
-
85036439514
-
-
personal communication
-
Blüthmann, H., personal communication.
-
-
-
Blüthmann, H.1
-
118
-
-
85036441685
-
-
in preparation
-
Labaud, et al., in preparation.
-
-
-
Labaud1
-
120
-
-
85036446121
-
-
in preparation
-
Gonzales, et al., in preparation.
-
-
-
Gonzales1
|