Failure of lymphopoiesis after adoptive transfer of NF-κB-deficient fetal liver cells

Immunity

Volumn 6, Issue 6, 1997, Pages 765-772

  Horwitz, Bruce H ^a,b   Scott, Martin L ^a   Cherry, Sara R ^a   Bronson, Roderick T ^c   Baltimore, David ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL SURVIVAL; FETUS; FETUS LIVER; GENE EXPRESSION REGULATION; LIVER CELL; LYMPHOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROLYMPHOCYTE;

EID: 0030837598     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80451-3     Document Type: Article

References (35)

1. Atchison, M.L., and Perry, R.P. (1987). The role of the K enhancer and its binding factor NF-κB in the developmental regulation of κ gene transcription. Cell 48, 121-128.
2. Baeuerle, P.A., and Baltimore, D. (1989). A 65-kD subunit of active NF-κB is required for inhibition of NF-κB by IκB. Genes Dev. 3, 1689-1698.
3. Baeuerle, P.A., and Baltimore, D. (1996). NF-κB: ten years after. Cell 87, 13-20.
4. Baeuerle, P.A., and Henkel, T. (1994). Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12, 141-179.
5. Baldwin, A.S. (1996). The NF-κB and IκB proteins: new discoveries and insights. Annu. Rev. Immunol. 14, 649-681.
6. Beg, A.A., and Baltimore, D. (1996). An essential role for NF-κB in preventing TNF-β-induced cell death. Science 274, 782-784.
7. Beg, A.A., Sha, W.C., Bronson, R.T., Ghosh, S., and Baltimore, D. (1995). Embryonic lethality and liver degeneration in mice lacking the ReIA component of NF-κB. Nature 376, 167-170.
8. Burkly, L., Hession, C., Ogata, L., Reilly, C., Marconi, L.A., Olson, D., Tizard, R., Cate, R., and Lo, D. (1995). Expression of ReIB is required for the development of thymic medulla and dendritic cells. Nature 373, 531-536.
9. Collins, L.S., and Dorshkind, K. (1987). A stromal cell line from myeloid long-term bone marrow cultures can support myelopoiesis and B lymphopoiesis. J. Immunol. 138, 1082-1087.
10. Cumano, A., and Paige, C.J. (1992). Enrichment and characterization of uncommitted B-cell precursors from fetal liver at day 12 of gestation. EMBO J. 11, 593-601.
11. Ghosh, S., Gifford, A.M., Riviere, L.R., Tempst, P., Nolan, G.P., and Baltimore, D. (1990). Cloning of the p50 DNA binding subunit of NF-κB: homology to rel and dorsal. Cell 62, 1019-1029.
12. Grilli, M., Chiu, J.J.-S., and Lenardo, M.J. (1993). NF-κB and Rel: participants in a multiform transcriptional regulatory system. Int. Rev. Cytol. 143, 1-62.
13. Kieran, M., Blank, V., Logeat, F., Vandekerckhove, J., Lottspeich, F., Bail, O.L., Urban, M.B., Kourilsky, P., Baeuerle, P., and Israel, A. (1990). The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product. Cell 62, 1007-1018.
14. Kirillov, A., Kistler, B., Mostoslavsky, R., Cedar, H., Wirth, T., and Bergman, Y. (1996). A role for nuclear NF-κB in B-cell-specific demethylation of the Igκ locus. Nature Genet. 13, 435-441.
15. Klug, C.A., Gerety, S.J., Pratik, C.S., Chen, Y.-Y., Rice, N.R., Rosenberg, N., and Singh, H. (1994). The v-abl tyrosine kinase negatively regulates NF-κB/Rel factors and blocks κ gene transcription in pre-B lymphocytes. Genes Dev. 8, 678-687.
16. Kontgen, F., Grumont, R.J., Strasser, A., Metcalf, D., Li, R., Tarlinton, D., and Gerondakis, S. (1995). Mice Lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes Dev. 9, 1965-1977.
17. Lenardo, M., Pierce, J.W., and Baltimore, D. (1987). Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility. Science 236, 1573-1577.
18. Lichtenstein, M., Keini, G., Cedar, H., and Bergman, Y. (1994). B cell-specific demethylation: a novel role for the intronic κ chain enhancer sequence. Cell 76, 913-923.
19. Liou, H.-C., and Baltimore, D. (1993). Regulation of the NF-κB/rel transcriptional factor and IκB inhibitor system. Curr. Opin. Cell Biol. 5, 477-487.
20. Liu, Z.-G., Hsu, H., Goeddel, D.V., and Karin, M. (1996). Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 87, 565-576.
21. Nolan, G.P., Ghosh, S., Liou, H.-S., Tempst, P., and Baltimore, D. (1991). DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide. Cell 64, 961-969.
22. Sachs, L. (1996). The control of hematopoiesis and leukemia: from basic biology to the clinic. Proc. Natl. Acad. Sci. USA 93, 4742-4749.
23. Scherer, D.C., Brockman, J.A., Bendall, H.H., Zhang, G.M., Ballard, D.W., and Oltz, E.M. (1996). Corepression of RelA and c-Rel inhibits immunoglobulin κ gene transcription and rearrangement in precursor B lymphocytes. Immunity 5, 563-574.
24. Schlissel, M.S., Corcoran, L.M., and Baltimore, D. (1991). Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription. J. Exp. Med. 173, 711-720.
25. Sen, R., and Baltimore, D. (1986a). Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism. Cell 47, 921-928.
26. Sen, R., and Baltimore, D. (1986b). Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46, 705-716.
27. Sha, W.C., Liou, H.-C., Tuomanen, E.I., and Baltimore, D. (1995). Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell 80, 321-330.
28. Shivdasani, R.A., and Orkin, S.H. (1996). The transcriptional control of hematopoiesis. Blood 87, 4025-4039.
29. Van Antwerp, D.J., Martin, S.J., Kafri, T., Green, D.R., and Verma, I.M. (1996). Suppression of TNF-δ-induced apoptosis by NF-κB. Science 274, 787-789.
30. Verma, I.M., Stevenson, J.K., Schwarz, E.M., Van Antwerp, D., and Miyamoto, S. (1995). Rel/NF-κB/IκB family: intimate tales of association and dissociation. Genes Dev. 9, 2723-2735.
31. Wang, C.-Y., Mayo, M.W., and Baldwin, A.S. (1996). TNF- and Cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 274, 784-787.
32. Weih, F., Carrasco, D., Durham, S.K., Barton, D.S., Rizzo, C.A., Ryseck, R.-P., Lira, S.A., and Bravo, R. (1995). Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family. Cell 80, 331-340.
33. Wu, M., Lee, H., Bellas, R.E., Schauer, S.L., Arsura, M., Katz, D., Fitzgerald, M.J., Rothstein, T.L., Sherr, D.H., and Sonnenshein, G.E. (1996). Inhibition of NF-κB/Rel induces apoptosis of murine B cells. EMBO J. 15, 4682-4690.
34. Xu, Y., Davidson, L., Alt, F.W., and Baltimore, D. (1996). Deletion of the Igκ light chain intronic enhancer/matrix attachment region impairs but does not abolish VκJκ rearrangement. Immunity 4, 377-385.
35. Zhu, C., Bogue, M.A., Lim, D.S., Hasty, P., and Roth, D.B. (1996). Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86, 379-389.