Differential signalling of both wild-type and Thr343Arg dopamine D2short receptor by partial agonists in a G-protein-dependent manner

Biochemical Pharmacology

Volumn 62, Issue 6, 2001, Pages 723-732

  Pauwels, Petrus J ^a,b   Tardif, Stéphanie ^a   Colpaert, Françis C ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

^b Fax: +33 563 71 43 63 ^*  (France)

Author keywords

35S GTP S binding and Ca2+ response; Differential signalling; G protein; Intrinsic ligand activity; Recombinant human dopamine D2short receptor

Indexed keywords

2 DIPROPYLAMINO 5 METHOXY 1 METHYLTETRALIN; ARGININE; BROMERGURIDE; BROMOCRIPTINE; CALCIUM ION; DOPAMINE 2 RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); LISURIDE; PROPYLNORAPOMORPHINE; THREONINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING SITE; CALCIUM CELL LEVEL; CHO CELL; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; HUMAN; KINETICS; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INTERACTION; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION;

ANIMALS; ARGININE; CALCIUM; CHO CELLS; CRICETINAE; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MUTATION; RECEPTORS, DOPAMINE D2; SIGNAL TRANSDUCTION; SULFUR RADIOISOTOPES; THREONINE;

EID: 0035885203     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00717-1     Document Type: Article

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