Novel (R)-2-amino-5-fluorotetralins: Dopaminergic antagonists and inverse agonists

Journal of Medicinal Chemistry

Volumn 39, Issue 22, 1996, Pages 4421-4429

  Malmberg, Åsa ^a,b   Höök, Berit Backlund ^a   Johansson, Anette M ^a   Hacksell, Uli ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b Astra Arcus AB ^*  (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

2 (BENZYLPROPYLAMINO) 5 FLUOROTETRALIN; 2 (BUTYLPROPYLAMINO) 5 FLUOROTETRALIN; 2 [[4 (8 AZA 7,9 DIOXOSPIRO[4,5]DECAN 8 YL)BUTYL]PROPYLAMINO] 5 FLUOROTETRALIN; 2 AMINO 5 FLUOROTETRALIN DERIVATIVE; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; NEUROLEPTIC AGENT; TETRALIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; DOPAMINE UPTAKE; DOPAMINERGIC TRANSMISSION; DRUG ANTAGONISM; DRUG EFFICACY; DRUG RECEPTOR BINDING; MOUSE; NONHUMAN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; MALE; RACLOPRIDE; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SALICYLAMIDES; TETRAHYDRONAPHTHALENES;

EID: 0029926567     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960350p     Document Type: Article

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