Ligand-receptor interactions as controlled by wild-type and mutant Thr370Lys α(2B)-adrenoceptor-G(α15) fusion proteins

Journal of Neurochemistry

Volumn 74, Issue 1, 2000, Pages 375-384

  Pauwels, P J ^a   Tardif, S ^a   Finana, F ^a   Wurch, T ^a   Colpaert, F C ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

Ca2+ response; Fusion protein; Intrinsic ligand activity; Mutagenesis of BBXXB motif; Recombinant human (2B) adrenoceptor

Indexed keywords

ADRENALIN; ALPHA 2B ADRENERGIC RECEPTOR; CALCIUM ION; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; LIGAND; LYSINE; MUTANT PROTEIN; RECEPTOR PROTEIN; THREONINE;

ALPHA ADRENERGIC STIMULATION; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CHO CELL; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TERTIARY STRUCTURE;

ADRENERGIC AGONISTS; ANIMALS; CALCIUM; CHO CELLS; CRICETINAE; DRUG RESISTANCE; EPINEPHRINE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; LIGANDS; MICE; MUTATION; RECEPTORS, ADRENERGIC; RECOMBINANT FUSION PROTEINS; VIRULENCE FACTORS, BORDETELLA;

ANIMALIA;

EID: 0033957415     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0740375.x     Document Type: Article

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