Inverse agonism and neutral antagonism at α(1a)- and α(1b)-adrenergic receptor subtypes

Molecular Pharmacology

Volumn 56, Issue 5, 1999, Pages 858-866

  Rossier, Olivier ^a   Abuin, Liliane ^a   Fanelli, Francesca ^b   Leonardi, Amedeo ^c   Cotecchia, Susanna ^a,d  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c Recordati SpA   (Italy)

^d University of Lausanne Departement de Pharmacologie et de Toxicologie   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; 8 [2 [2 (5 CHLORO 2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4,5]DECANE 7,9 DIONE; 8 [2 [4 (5 CHLORO 2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; 8 [3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]PROPYLCARBAMOYL] 3 METHYLFLAVONE; 8 [3 [4 (5 CHLORO 2 METHOXYPHENYL) 1 PIPERAZINYL]PROPYLCARBAMOYL] 2 CYCLOHEXYL 3 METHYL 4H 1 BENZOPYRAN 4 ONE; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1B ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; INOSITOL PHOSPHATE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ADRENERGIC RECEPTOR BLOCKING; ADRENERGIC SYSTEM; ANIMAL CELL; ARTICLE; DNA TRANSFECTION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; LIGAND BINDING; MOLECULAR MODEL; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0032749712     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.56.5.858     Document Type: Article

References (19)

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