-
1
-
-
0030581151
-
Induction of apoptosis program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu X, Kim N, Yang J, Jemmerson R, Wang X. Induction of apoptosis program in cell-free extracts: requirement for dATP and cytochrome c. Cell. 1996;86:147-157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
2
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 1997;91:479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
-
3
-
-
0030745646
-
Apaf-1 a human protein homologous to C. elegans CED-4 participates in cytochrome c-dependent activation of caspase-3
-
Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1 a human protein homologous to C. elegans CED-4 participates in cytochrome c-dependent activation of caspase-3. Cell. 1997;90:405-413.
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
6
-
-
0344348821
-
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
-
Hu Y, Benedict MA, Ding L, Núñez G. Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis. EMBO J. 1999;18:3586-3595.
-
(1999)
EMBO J
, vol.18
, pp. 3586-3595
-
-
Hu, Y.1
Benedict, M.A.2
Ding, L.3
Núñez, G.4
-
7
-
-
0033542482
-
Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1
-
Qin H, Srinivasula SM, Wu G, Fernandes-Alnemri T, Alnemri ES, Shi Y. Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1. Nature. 1999;399:549-557.
-
(1999)
Nature
, vol.399
, pp. 549-557
-
-
Qin, H.1
Srinivasula, S.M.2
Wu, G.3
Fernandes-Alnemri, T.4
Alnemri, E.S.5
Shi, Y.6
-
8
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
Soengas MS, Alarcon RM, Yoshida H, et al. Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science. 1999;284:156-159.
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcon, R.M.2
Yoshida, H.3
-
9
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science. 1997;275:1132-1136.
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
10
-
-
0033120383
-
Subcellular distribution and redistribution of Bcl-2 family proteins in human leukemia cells undergoing apoptosis
-
Jia L, Macey MG, Yin Y, Newland AC, Kelsey SM. Subcellular distribution and redistribution of Bcl-2 family proteins in human leukemia cells undergoing apoptosis. Blood. 1999;93:2353-2359.
-
(1999)
Blood
, vol.93
, pp. 2353-2359
-
-
Jia, L.1
Macey, M.G.2
Yin, Y.3
Newland, A.C.4
Kelsey, S.M.5
-
11
-
-
0033529634
-
Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex
-
Cain K, Brown DG, Langlais C, Cohen GM. Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex. J Biol Chem. 1999;274:22686-22692.
-
(1999)
J Biol Chem
, vol.274
, pp. 22686-22692
-
-
Cain, K.1
Brown, D.G.2
Langlais, C.3
Cohen, G.M.4
-
12
-
-
0033597923
-
Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region
-
Adrain C, Slee EA, Harte MT, Martin SJ. Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region. J Biol Chem. 1999;274:20855-20860.
-
(1999)
J Biol Chem
, vol.274
, pp. 20855-20860
-
-
Adrain, C.1
Slee, E.A.2
Harte, M.T.3
Martin, S.J.4
-
13
-
-
0032509354
-
WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation
-
Hu Y, Ding L, Spencer DM, Núñez G. WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation. J Biol Chem. 1998;273:33489-33494.
-
(1998)
J Biol Chem
, vol.273
, pp. 33489-33494
-
-
Hu, Y.1
Ding, L.2
Spencer, D.M.3
Núñez, G.4
-
14
-
-
0033580926
-
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
-
Saleh A, Srinivasula SM, Acharya S, Fishel R, Alnemri ES. Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J Biol Chem. 1999;274:17941-17945.
-
(1999)
J Biol Chem
, vol.274
, pp. 17941-17945
-
-
Saleh, A.1
Srinivasula, S.M.2
Acharya, S.3
Fishel, R.4
Alnemri, E.S.5
-
15
-
-
0032545286
-
Granzyme B mimics apical caspases: Description of a unified pathway for trans-activation of executioner caspase-3 and -7
-
Yang X, Stennicke HR, Wang B, et al. Granzyme B mimics apical caspases: description of a unified pathway for trans-activation of executioner caspase-3 and -7. J Biol Chem. 1998;273:34278-34283.
-
(1998)
J Biol Chem
, vol.273
, pp. 34278-34283
-
-
Yang, X.1
Stennicke, H.R.2
Wang, B.3
-
16
-
-
0032493870
-
Differential requirement for caspase-9 in apoptotic pathways in vivo
-
Hakem R, Hakem A, Duncan GS, et al. Differential requirement for caspase-9 in apoptotic pathways in vivo. Cell. 1998;94:339-352.
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
-
17
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase-activation in mice lacking caspase-9
-
Kuida K, Haydar TF, Kuan CY, et al. Reduced apoptosis and cytochrome c-mediated caspase-activation in mice lacking caspase-9. Cell. 1998;94:325-337.
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.Y.3
-
18
-
-
0032544449
-
Apaf-1 (CED-4 homolog) regulates programmed cell death in mammalian development
-
Cecconi F, Alvarez-Bolado G, Meyer BI, Roth KA, Gruss P. Apaf-1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell. 1998;94:727-737.
-
(1998)
Cell
, vol.94
, pp. 727-737
-
-
Cecconi, F.1
Alvarez-Bolado, G.2
Meyer, B.I.3
Roth, K.A.4
Gruss, P.5
-
19
-
-
0032544564
-
Apaf-1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida H, Kong YY, Yoshida R, et al. Apaf-1 is required for mitochondrial pathways of apoptosis and brain development. Cell. 1998;94:739-750.
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
-
20
-
-
0032532653
-
Overexpression Apaf-1 promotes apoptosis of untreated and paclitaxel- or etoposide-treated HL-60 cells
-
Perkins C, Kim CN, Fang G, Bhalla KN. Overexpression Apaf-1 promotes apoptosis of untreated and paclitaxel- or etoposide-treated HL-60 cells. Cancer Res. 1998;58:4561-4566.
-
(1998)
Cancer Res
, vol.58
, pp. 4561-4566
-
-
Perkins, C.1
Kim, C.N.2
Fang, G.3
Bhalla, K.N.4
-
21
-
-
0033104331
-
Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis
-
Srinivasula SM, Ahmad M, Guo Y, et al. Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis. Cancer Res. 1999;59:999-1002.
-
(1999)
Cancer Res
, vol.59
, pp. 999-1002
-
-
Srinivasula, S.M.1
Ahmad, M.2
Guo, Y.3
-
22
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
-
Deveraux QL, Roy N, Stennicke HR, et al. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 1998;17:2215-2223.
-
(1998)
EMBO J
, vol.17
, pp. 2215-2223
-
-
Deveraux, Q.L.1
Roy, N.2
Stennicke, H.R.3
-
23
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell. 2000;102:33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
24
-
-
0034680876
-
Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway
-
Srinivasula SM, Datta P, Fan X-J, Fernandes-Alnemri T, Huang Z, Alnemri ES. Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway. J Biol Chem. 2000;275:36152-36157.
-
(2000)
J Biol Chem
, vol.275
, pp. 36152-36157
-
-
Srinivasula, S.M.1
Datta, P.2
Fan, X.-J.3
Fernandes-Alnemri, T.4
Huang, Z.5
Alnemri, E.S.6
-
25
-
-
0029979377
-
Increased activity and sensitivity of mitochondrial respiratory enzymes to TNF-α-induced inhibition is associated with increased cytotoxicity in drug-resistant leukemic cell lines
-
Jia L, Kelsey SM, Grahn MF, Newland AC. Increased activity and sensitivity of mitochondrial respiratory enzymes to TNF-α-induced inhibition is associated with increased cytotoxicity in drug-resistant leukemic cell lines. Blood. 1996;87:2401-2410.
-
(1996)
Blood
, vol.87
, pp. 2401-2410
-
-
Jia, L.1
Kelsey, S.M.2
Grahn, M.F.3
Newland, A.C.4
-
26
-
-
0030883558
-
Inhibition of autophagy abrogates TNF-α-induced apoptosis in human T-lymphoblastic leukaemic cells
-
Jia L, Doumashkin RR, Allen PD, Gray AB, Newland AC, Kelsey SM. Inhibition of autophagy abrogates TNF-α-induced apoptosis in human T-lymphoblastic leukaemic cells. Br J Haematol. 1997a;98:673-685.
-
(1997)
Br J Haematol
, vol.98
, pp. 673-685
-
-
Jia, L.1
Doumashkin, R.R.2
Allen, P.D.3
Gray, A.B.4
Newland, A.C.5
Kelsey, S.M.6
-
27
-
-
0030608832
-
Mitochondrial ultracondensation, but not swelling, is involved in TNF-α-induced apoptosis in human T-lymphoblastic leukaemic cells
-
Jia L, Dourmashkin RR, Newland AC, Kelsey SM. Mitochondrial ultracondensation, but not swelling, is involved in TNF-α-induced apoptosis in human T-lymphoblastic leukaemic cells. Leuk Res. 1997;21:973-983.
-
(1997)
Leuk Res
, vol.21
, pp. 973-983
-
-
Jia, L.1
Dourmashkin, R.R.2
Newland, A.C.3
Kelsey, S.M.4
-
28
-
-
0019991171
-
A fluorescence enhancement assay for cellular DNA damage
-
Kanter PM, Schwartz HS. A fluorescence enhancement assay for cellular DNA damage. Mol Pharmacol. 1982;22:145-151.
-
(1982)
Mol Pharmacol
, vol.22
, pp. 145-151
-
-
Kanter, P.M.1
Schwartz, H.S.2
-
29
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science. 1997;275:1129-1132.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
-
30
-
-
0030613796
-
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
-
Vander-Heiden MG, Chandel NS, Williamson EK, Schumacker PT, Thompson CB. Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell. 1997;91:627-637.
-
(1997)
Cell
, vol.91
, pp. 627-637
-
-
Vander-Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
Schumacker, P.T.4
Thompson, C.B.5
-
31
-
-
0030924405
-
Mitochondrial electron transport chain activity, but not ATP synthesis, is required for drug-induced apoptosis in human leukaemic cells: A possible novel mechanism of regulating drug resistance
-
Jia L, Allen PD, Macey MG, Grahn MF, Newland AC, Kelsey SM. Mitochondrial electron transport chain activity, but not ATP synthesis, is required for drug-induced apoptosis in human leukaemic cells: a possible novel mechanism of regulating drug resistance. B r J Haematol. 1997b;98:686-698.
-
(1997)
B r J Haematol
, vol.98
, pp. 686-698
-
-
Jia, L.1
Allen, P.D.2
Macey, M.G.3
Grahn, M.F.4
Newland, A.C.5
Kelsey, S.M.6
-
32
-
-
0032905030
-
Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB
-
Wang CY, Cusack JC Jr, Liu R, Baldwin AS Jr. Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB. Nat Med. 1999;5:412-417.
-
(1999)
Nat Med
, vol.5
, pp. 412-417
-
-
Wang, C.Y.1
Cusack J.C., Jr.2
Liu, R.3
Baldwin A.S., Jr.4
-
33
-
-
0030701895
-
Comparison of caspases activation and subcellular localization in HL-60 and K562 cells undergoing etoposicle-induced apoptosis
-
Martins LM, Mesner PW, Kottke TJ, et al. Comparison of caspases activation and subcellular localization in HL-60 and K562 cells undergoing etoposicle-induced apoptosis. Blood. 1997;90:4283-4296.
-
(1997)
Blood
, vol.90
, pp. 4283-4296
-
-
Martins, L.M.1
Mesner, P.W.2
Kottke, T.J.3
-
34
-
-
0034142368
-
Arsenic induces apoptosis of multidrug-resistant human myeloid leukemia cells that express Bcr-Abl or overexpress MDR, MRP, Bcl-2 or Bcl-x(L)
-
Perkins C, Kim CN, Fang G, Bhalla KN. Arsenic induces apoptosis of multidrug-resistant human myeloid leukemia cells that express Bcr-Abl or overexpress MDR, MRP, Bcl-2 or Bcl-x(L). Blood. 2000;95:1014-1022.
-
(2000)
Blood
, vol.95
, pp. 1014-1022
-
-
Perkins, C.1
Kim, C.N.2
Fang, G.3
Bhalla, K.N.4
|