-
1
-
-
0032487923
-
Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
-
Soignet S, Maslak P, Wang ZG, et al. Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. N Engl J Med. 1998;339:1341.
-
(1998)
N Engl J Med
, vol.339
, pp. 1341
-
-
Soignet, S.1
Maslak, P.2
Wang, Z.G.3
-
2
-
-
0032554052
-
Arsenic and apoptosis in the treatment of acute promyelocytic leukemia
-
Look AT. Arsenic and apoptosis in the treatment of acute promyelocytic leukemia. J Natl Cancer Inst. 1998;90:86.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 86
-
-
Look, A.T.1
-
3
-
-
0010740572
-
3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RARα/PML proteins
-
3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RARα/PML proteins. Blood. 1996;88:1052.
-
(1996)
Blood
, vol.88
, pp. 1052
-
-
Chen, G.Q.1
Zhu, J.2
Shi, X.G.3
-
4
-
-
0030610686
-
3 exerts dose-dependent dual effects on APL cells
-
3 exerts dose-dependent dual effects on APL cells. Blood. 1997; 89:3345.
-
(1997)
Blood
, vol.89
, pp. 3345
-
-
Chen, G.Q.1
Shi, X.G.2
Tang, W.3
-
5
-
-
0032170898
-
Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARα independent manner
-
Wang ZG, Rivi R, Delva L, et al. Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARα independent manner. Blood. 1998;92:1497.
-
(1998)
Blood
, vol.92
, pp. 1497
-
-
Wang, Z.G.1
Rivi, R.2
Delva, L.3
-
6
-
-
0033105268
-
Arsenic trioxide and melarsoprol induce apoptosis in plasma cell lines and in plasma cells from myeloma patients
-
Rousselo P, Labaume S, Maralleau J, et al. Arsenic trioxide and melarsoprol induce apoptosis in plasma cell lines and in plasma cells from myeloma patients. Cancer Res. 1999;59:1041.
-
(1999)
Cancer Res
, vol.59
, pp. 1041
-
-
Rousselo, P.1
Labaume, S.2
Maralleau, J.3
-
7
-
-
0032910345
-
Arsenic trioxide and interferon-α synergize to induce cell cycle arrest and apoptosis in human T-cell lymphotropic virus type I-transformed cells
-
Bazarbachi A, El-Sabban M, Nasr R, et al. Arsenic trioxide and interferon-α synergize to induce cell cycle arrest and apoptosis in human T-cell lymphotropic virus type I-transformed cells. Blood. 1999;93:278.
-
(1999)
Blood
, vol.93
, pp. 278
-
-
Bazarbachi, A.1
El-Sabban, M.2
Nasr, R.3
-
8
-
-
0038125071
-
Comparative activity of melarsoprol and arsenic trioxide in chronic B-cell leukemia lines
-
Konig A, Wrazel L, Warrell R Jr, et al. Comparative activity of melarsoprol and arsenic trioxide in chronic B-cell leukemia lines. Blood. 1997;90: 562.
-
(1997)
Blood
, vol.90
, pp. 562
-
-
Konig, A.1
Wrazel, L.2
Warrell Jr., R.3
-
9
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science. 1997;275:1129.
-
(1997)
Science
, vol.275
, pp. 1129
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
-
10
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
Adams J, Cory S. The Bcl-2 protein family: arbiters of cell survival. Science. 1998;281:1322.
-
(1998)
Science
, vol.281
, pp. 1322
-
-
Adams, J.1
Cory, S.2
-
11
-
-
0032532653
-
Overexpression of Apaf-1 promotes apoptosis of untreated and paxlitaxel- or etoposide-treated HL-60 cells
-
Perkins C, Kim C, Fang G, Bhalla K. Overexpression of Apaf-1 promotes apoptosis of untreated and paxlitaxel- or etoposide-treated HL-60 cells. Cancer Res. 1998;58:4561.
-
(1998)
Cancer Res
, vol.58
, pp. 4561
-
-
Perkins, C.1
Kim, C.2
Fang, G.3
Bhalla, K.4
-
12
-
-
0032575752
-
Mitochondria and apoptosis
-
Green D, Reed J. Mitochondria and apoptosis. Science. 1998;281:1309.
-
(1998)
Science
, vol.281
, pp. 1309
-
-
Green, D.1
Reed, J.2
-
13
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
Hockenbery D, Oltvai Z, Yin XM, Milliman C, Korsmeyer. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell. 1993;75:241.
-
(1993)
Cell
, vol.75
, pp. 241
-
-
Hockenbery, D.1
Oltvai, Z.2
Yin, X.M.3
Milliman, C.4
Korsmeyer5
-
14
-
-
0032933610
-
Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system
-
Dai J, Weinberg RS, Waxman S, Jing Y. Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system. Blood. 1999;93:268.
-
(1999)
Blood
, vol.93
, pp. 268
-
-
Dai, J.1
Weinberg, R.S.2
Waxman, S.3
Jing, Y.4
-
15
-
-
0031045308
-
Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells
-
Huang Y, Ibrado AM, Reed JC, et al. Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells. Leukemia. 1997;11:253.
-
(1997)
Leukemia
, vol.11
, pp. 253
-
-
Huang, Y.1
Ibrado, A.M.2
Reed, J.C.3
-
16
-
-
0029131231
-
BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: A mechanism of resistance to multiple anticancer agents
-
Bedi A, Barber JP, Bedi GC, et al. BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: a mechanism of resistance to multiple anticancer agents. Blood. 1995;86:1148.
-
(1995)
Blood
, vol.86
, pp. 1148
-
-
Bedi, A.1
Barber, J.P.2
Bedi, G.C.3
-
17
-
-
0027979832
-
BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death
-
McGahon A, Bissonnette R, Schmitt M, Cotter KM, Green DR, Cotter TG. BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death. Blood 1994;83:1179.
-
(1994)
Blood
, vol.83
, pp. 1179
-
-
McGahon, A.1
Bissonnette, R.2
Schmitt, M.3
Cotter, K.M.4
Green, D.R.5
Cotter, T.G.6
-
18
-
-
0032032270
-
Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome c and activation of caspase-3
-
Amarante-Mendes G, Kim C, Liu L, et al. Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome c and activation of caspase-3. Blood. 1998;91:1700.
-
(1998)
Blood
, vol.91
, pp. 1700
-
-
Amarante-Mendes, G.1
Kim, C.2
Liu, L.3
-
21
-
-
3643104150
-
Accelerated discovery: Therapeutic targeting of transcription of acute promyelocytic leukemia by use of an inhibitor of histone deacetylase
-
Warrell R Jr, He LZ, Richon V, Calleja E, Pandolfi PP. Accelerated discovery: therapeutic targeting of transcription of acute promyelocytic leukemia by use of an inhibitor of histone deacetylase. J Natl Cancer Inst. 1998;90:1621.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1621
-
-
Warrell Jr., R.1
He, L.Z.2
Richon, V.3
Calleja, E.4
Pandolfi, P.P.5
-
22
-
-
0032539890
-
A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases
-
Richon V, Emiliani S, Verdin E, et al. A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc Natl Acad Sci U S A. 1998;95:3003.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3003
-
-
Richon, V.1
Emiliani, S.2
Verdin, E.3
-
23
-
-
0032142918
-
Roles of histones acetyltransferases and deacetylases in gene regulation
-
Kuo MH, Allis D. Roles of histones acetyltransferases and deacetylases in gene regulation. Bioessays. 1998;20:615.
-
(1998)
Bioessays
, vol.20
, pp. 615
-
-
Kuo, M.H.1
Allis, D.2
-
24
-
-
0030916417
-
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
-
Liu X, Zou H, Slaughter C, Wang X, DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell. 1997;89:175.
-
(1997)
Cell
, vol.89
, pp. 175
-
-
Liu, X.1
Zou, H.2
Slaughter, C.3
Wang, X.4
-
25
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participated in cytochrome c-dependent activation of caspase-3
-
Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participated in cytochrome c-dependent activation of caspase-3. Cell. 1997;90: 405.
-
(1997)
Cell
, vol.90
, pp. 405
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
26
-
-
0032555716
-
Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell. 1998;94:481.
-
(1998)
Cell
, vol.94
, pp. 481
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
27
-
-
0029792981
-
L inhibits Ara-C-induced CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells
-
L inhibits Ara-C-induced CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells. Cancer Res. 1996;56:4743.
-
(1996)
Cancer Res
, vol.56
, pp. 4743
-
-
Ibrado, A.M.1
Huang, Y.2
Fang, G.3
Liu, L.4
Bhalla, K.5
-
28
-
-
0016640079
-
Human chronic myelogenous leukemia cell line with positive Philadelphia chromosome
-
Lozzio CB, Lozzio BB. Human chronic myelogenous leukemia cell line with positive Philadelphia chromosome. Blood. 1975;45:321.
-
(1975)
Blood
, vol.45
, pp. 321
-
-
Lozzio, C.B.1
Lozzio, B.B.2
-
29
-
-
0021952694
-
Isolation and characterization of an anthracycline-resistant human leukemic cell line
-
Bhalla K, Hindenburg A, Taub R, Grant S. Isolation and characterization of an anthracycline-resistant human leukemic cell line. Cancer Res. 1985;45:3657.
-
(1985)
Cancer Res
, vol.45
, pp. 3657
-
-
Bhalla, K.1
Hindenburg, A.2
Taub, R.3
Grant, S.4
-
31
-
-
0031032294
-
L antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents
-
L antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res 1997;57:62.
-
(1997)
Cancer Res
, vol.57
, pp. 62
-
-
Decaudin, D.1
Geley, S.2
Hirsch, T.3
-
32
-
-
0029906828
-
BAX-induced cell death may not require interteukin 1 β-converting enzyme-like proteases
-
Xiang J, Chao DT, Korsmeyer SJ. BAX-induced cell death may not require interteukin 1 β-converting enzyme-like proteases. Proc Natl Acad Sci U S A. 1996;93:14,559.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
-
-
Xiang, J.1
Chao, D.T.2
Korsmeyer, S.J.3
-
33
-
-
0030941675
-
Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the induction of differentiation and drug-mediated apoptosis in human myeloid leukemia cells (HI-60)
-
Freemerman AJ, Vrana JA, Tombes RM, et al. Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the induction of differentiation and drug-mediated apoptosis in human myeloid leukemia cells (HI-60). Leukemia. 1997;11:504.
-
(1997)
Leukemia
, vol.11
, pp. 504
-
-
Freemerman, A.J.1
Vrana, J.A.2
Tombes, R.M.3
-
34
-
-
0000928694
-
Arsenic targets tubulins to induce apoptosis in myeloid leukemia cells
-
Li YM, Broome J. Arsenic targets tubulins to induce apoptosis in myeloid leukemia cells. Cancer Res. 1999;59:776.
-
(1999)
Cancer Res
, vol.59
, pp. 776
-
-
Li, Y.M.1
Broome, J.2
-
35
-
-
0029852727
-
S induces differentiation and sensitizes chronic myelogenous leukemia-blast crisis K562 cells to 1-B-D-Arabinofuranosylcytosine-mediated differentiation and apoptosis
-
S induces differentiation and sensitizes chronic myelogenous leukemia-blast crisis K562 cells to 1-B-D-Arabinofuranosylcytosine-mediated differentiation and apoptosis. Cell Growth Differ. 1996;7:1617.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 1617
-
-
Ray, S.1
Bullock, G.2
Nunez, G.3
-
36
-
-
0028167771
-
1-β-D-arabinofuranosylcytosine-, mitoxantrone- and paclitaxel-induced apoptosis in HL-60 cells: Improved method for detection of internucleosomal DNA fragmentation
-
Ray S, Ponnathpur V, Huang Y, et al. 1-β-D-arabinofuranosylcytosine-, mitoxantrone- and paclitaxel-induced apoptosis in HL-60 cells: improved method for detection of internucleosomal DNA fragmentation. Cancer Chemother Pharmacol. 1994;34:365.
-
(1994)
Cancer Chemother Pharmacol
, vol.34
, pp. 365
-
-
Ray, S.1
Ponnathpur, V.2
Huang, Y.3
-
37
-
-
0027989808
-
Annexin-V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
-
Koopman G, Reutelingsperger CPM, Kuijten GAM, Keehnen RMJ, Pals ST, van Oers MHJ. Annexin-V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood. 1994;84:1415.
-
(1994)
Blood
, vol.84
, pp. 1415
-
-
Koopman, G.1
Reutelingsperger, C.P.M.2
Kuijten, G.A.M.3
Keehnen, R.M.J.4
Pals, S.T.5
Van Oers, M.H.J.6
-
38
-
-
0031888955
-
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
-
Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature. 1998;391:43.
-
(1998)
Nature
, vol.391
, pp. 43
-
-
Enari, M.1
Sakahira, H.2
Yokoyama, H.3
Okawa, K.4
Iwamatsu, A.5
Nagata, S.6
-
39
-
-
0032582539
-
Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis
-
Tang D, Kidd V. Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis. J Biol Chem.1998;273:28,549.
-
(1998)
J Biol Chem
, vol.273
-
-
Tang, D.1
Kidd, V.2
-
40
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/ caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/ caspase-9 complex initiates an apoptotic protease cascade. Cell. 1997;91:479.
-
(1997)
Cell
, vol.91
, pp. 479
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
-
41
-
-
0029807585
-
BID: A novel BH3 domain-only death agonist
-
Wang K, Yin XM, Chao DT, Milliman CL, Korsmeyer SJ. BID: a novel BH3 domain-only death agonist. Genes Dev. 1996;10:2859.
-
(1996)
Genes Dev
, vol.10
, pp. 2859
-
-
Wang, K.1
Yin, X.M.2
Chao, D.T.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
42
-
-
0032549001
-
Rb Interacts with histone deacetylase to repress transcription
-
Luo R, Postigo A, Dean D. Rb Interacts with histone deacetylase to repress transcription. Cell. 1998;92:463.
-
(1998)
Cell
, vol.92
, pp. 463
-
-
Luo, R.1
Postigo, A.2
Dean, D.3
-
43
-
-
0033526358
-
Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations
-
Zhu X-H, Shen Y-L, Jing Y-k, et al. Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations. J Natl Cancer Inst. 1999;91: 772.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 772
-
-
Zhu, X.-H.1
Shen, Y.-L.2
Jing, Y.-K.3
-
44
-
-
0033526398
-
Arsenic trioxide, a novel mitochondriotoxic anticancer agent?
-
Kroemer G, de Thé H. Arsenic trioxide, a novel mitochondriotoxic anticancer agent? J Natl Cancer Inst. 1999; 91:743.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 743
-
-
Kroemer, G.1
De Thé, H.2
-
45
-
-
0032544268
-
Apoptotic pathways: The roads to ruin
-
Green D. Apoptotic pathways: the roads to ruin. Cell. 1998;94:695.
-
(1998)
Cell
, vol.94
, pp. 695
-
-
Green, D.1
-
46
-
-
0031762486
-
Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells
-
Ibrado AM, Kim CN, Bhalla K. Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells. Leukemia. 1998; 12:1930.
-
(1998)
Leukemia
, vol.12
, pp. 1930
-
-
Ibrado, A.M.1
Kim, C.N.2
Bhalla, K.3
-
48
-
-
0025883201
-
Selective inhibition of leukemia cell proliferation by Bcr-Abl antisense oligodeoxynucleotides
-
Szczylik C, Skorski T, Nicolaides N, et al. Selective inhibition of leukemia cell proliferation by Bcr-Abl antisense oligodeoxynucleotides. Science. 1991;253:562.
-
(1991)
Science
, vol.253
, pp. 562
-
-
Szczylik, C.1
Skorski, T.2
Nicolaides, N.3
-
49
-
-
0033585504
-
In vitro eradication of human Bcr/Abl-positive leukemia cells with an ABL kinase inhibitor
-
le Courte P, Malogni L, Cleris L, et al. In vitro eradication of human Bcr/Abl-positive leukemia cells with an ABL kinase inhibitor. J Natl Cancer Inst. 1999;91:163.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 163
-
-
Le Courte, P.1
Malogni, L.2
Cleris, L.3
-
52
-
-
0032482318
-
Transcription: Gene control by targeted histone acetylation
-
Imof A, Wolffe A. Transcription: gene control by targeted histone acetylation. Curr Biol. 1998;8: 422.
-
(1998)
Curr Biol
, vol.8
, pp. 422
-
-
Imof, A.1
Wolffe, A.2
-
53
-
-
0032511884
-
Histone acetyltransterase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A
-
Ait-Si-Ali S, Ramirez S, Barre F-X, et al. Histone acetyltransterase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A. Nature. 1998;396:184.
-
(1998)
Nature
, vol.396
, pp. 184
-
-
Ait-Si-Ali, S.1
Ramirez, S.2
Barre, F.-X.3
-
54
-
-
0032506542
-
Regulation of activity of the transcription factor GATA-1 by acetylation
-
Boyes J, Byfield P, Nakatani Y, Ogryzko V. Regulation of activity of the transcription factor GATA-1 by acetylation. Nature. 1998;396:594.
-
(1998)
Nature
, vol.396
, pp. 594
-
-
Boyes, J.1
Byfield, P.2
Nakatani, Y.3
Ogryzko, V.4
|