Mitochondrial electron transport chain activity, but not ATP synthesis, is required for drug-induced apoptosis in human leukaemic cells: A possible novel mechanism of regulating drug resistance

British Journal of Haematology

Volumn 98, Issue 3, 1997, Pages 686-698

  Jia, Li ^a   Allen, Paul D ^a   Macey, Marion G ^a   Grahn, Michael F ^a   Newland, Adrian C ^a   Kelsey, Stephen M ^a,b  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b ROYAL LONDON HOSPITAL   (United Kingdom)

Author keywords

F1F0 ATPase; Mitochondrial electron transport chain (ETC); Multidrug resistance (MDR); P glycoprotein (Pgp); Vinblastine

Indexed keywords

ADENOSINE TRIPHOSPHATE; DNA FRAGMENT; MITOCHONDRIAL DNA; VINBLASTINE;

APOPTOSIS; ARTICLE; CELL CYCLE; CONTROLLED STUDY; DRUG RESISTANCE; HUMAN; HUMAN CELL; LEUKEMIA; LEUKEMIA CELL LINE; MICROTUBULE; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; RESPIRATORY CHAIN;

EID: 0030924405     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.2683085.x     Document Type: Article

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