Increased activity and sensitivity of mitochondrial respiratory enzymes to tumor necrosis factor α-mediated inhibition is associated with increased cytotoxicity in drug-resistant leukemic cell lines

Blood

Volumn 87, Issue 6, 1996, Pages 2401-2410

  Jia, Li ^a   Kelsey, Stephen M ^a   Grahn, Michael F ^a   Jiang, Xu Rong ^a   Newland, Adrian C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL ENZYME; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG RESISTANCE; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL;

ADENOSINE DIPHOSPHATE; CELL DEATH; CELLS, CULTURED; DAUNORUBICIN; DEPRESSION, CHEMICAL; DRUG RESISTANCE, NEOPLASM; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX II; ELECTRON TRANSPORT COMPLEX IV; ENZYME INHIBITORS; FREE RADICALS; GLYCOLYSIS; HUMANS; LEUKEMIA; LEUKEMIA, MYELOID, CHRONIC; LEUKEMIA, T-CELL, ACUTE; MITOCHONDRIA; MULTIENZYME COMPLEXES; NAD(P)H DEHYDROGENASE (QUINONE); NEOPLASM PROTEINS; OXIDOREDUCTASES; PARAQUAT; SUCCINATE DEHYDROGENASE; SUPEROXIDES; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; VINBLASTINE;

EID: 0029979377     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.6.2401.bloodjournal8762401     Document Type: Article

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