메뉴 건너뛰기




Volumn 4, Issue 6, 2001, Pages 392-401

Anticancer therapy with novel tubulin-interacting drugs

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; AURISTATIN PE; BMS 184476; BMS 185660; BMS 188797; BMS 275183; CRYPTOPHYCIN 52; CRYPTOPHYCIN 55; CRYPTOPHYCIN DERIVATIVE; DISCODERMOLIDE; DOLASTATIN; DOLASTATIN 10; EPOTHILONE DERIVATIVE; FR 182877; NAVELBINE; ORTATAXEL; PACLITAXEL; PACLITAXEL POLIGLUMEX; PNU 166945; RHIZOXIN; RPR 109881A; TAXANE DERIVATIVE; TAXOPREXIN; TUBULIN; TXD 258; UNCLASSIFIED DRUG; VINCA ALKALOID; VINFLUNINE;

EID: 0035744348     PISSN: 13687646     EISSN: None     Source Type: Journal    
DOI: 10.1054/drup.2002.0230     Document Type: Review
Times cited : (129)

References (111)
  • 2
    • 0031043119 scopus 로고    scopus 로고
    • The role of Multidrug Resistance-associated Protein (MRP) gene expression in drug resistance
    • (1997) Anti-Cancer Drugs , vol.8 , pp. 17-25
    • Kavallaris, M.1
  • 16
    • 0034741810 scopus 로고    scopus 로고
    • Modifications in the "upper" velbenamine part of the vinca alkaloids have major implications for tubulin interacting activities
    • (2001) Curr Pharm Des , vol.7 , pp. 1181-1197
    • Fahy, J.1
  • 19
    • 0034858240 scopus 로고    scopus 로고
    • Vinflunine, a second generation novel vinca alkaloid with a distinctive pharmacological profile, now in clinical development and prospects for future mitotic blockers
    • (2001) Curr Pharm Des , vol.7 , pp. 1199-1212
    • Hill, B.T.1
  • 20
    • 0034960408 scopus 로고    scopus 로고
    • Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic vinca alkaloids vinorelbine and its newer derivative vinflunine
    • (2001) Mol Pharmacol , vol.60 , pp. 225-232
    • Ngan, V.K.1    Bellman, K.2    Hill, B.T.3
  • 23
    • 3943082709 scopus 로고    scopus 로고
    • Significant antianglogenic activity and marked inhibition of growth of an orthotopic colon cancer model and colon cancer liver metastases by vinflunine, the most recent vinca alkaloid in clinical development
    • in press
    • (2002) Proc Am Assoc Cancer Res , pp. 43
    • Kruczynski, A.1    Ricome, C.2    Astruc, J.3
  • 24
    • 0034918410 scopus 로고    scopus 로고
    • Markedly diminished drug-resistance inducing properties of vinflunine (20′,20′-difluoro-3′,4′-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro, with clinical implications
    • (2001) Cancer Chemother Pharmacol , vol.48 , pp. 62-70
    • Etiévant, C.1    Kruczynski, A.2    Tait, A.S.3
  • 27
    • 0033861796 scopus 로고    scopus 로고
    • Cryptophycin 52 and cryptophycin 55 in sequential and simultaneous combination treatment regimens in human tumour xenografts
    • (2000) In Vivo , vol.14 , pp. 471-480
    • Teicher, B.A.1    Forler, P.2    Menon, K.3
  • 36
    • 0035971541 scopus 로고    scopus 로고
    • An antimicrotubule agent, TZT-1027, does not induce neuropathologic alterations which are detected after administration of vincristine or paclitaxel in animal models
    • (2001) Toxicol Lett , vol.121 , pp. 97-106
    • Ogawa, T.1    Mimura, Y.2    Isowa, K.3
  • 37
    • 0035133804 scopus 로고    scopus 로고
    • D-24851, a novel synthetic microtubule inhibitor, exerts curative antitumoral activity in vivo, shows efficacy toward multidrug-resistant tumor cells, and lacks neurotoxicity
    • (2001) Cancer Res , vol.61 , pp. 392-399
    • Bacher, G.1    Nickel, B.2    Emig, P.3
  • 38
    • 0035879010 scopus 로고    scopus 로고
    • A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors
    • (2001) Cancer Res , vol.61 , pp. 5480-5485
    • Tahir, S.K.1    Han, E.K.2    Credo, B.3
  • 45
    • 0034518173 scopus 로고    scopus 로고
    • Structural basis for the interaction of tubulin with proteins and drugs that affect microtubule stability
    • (2000) Annu Rev Cell Dev Biol , vol.16 , pp. 89-111
    • Downing, K.H.1
  • 47
    • 0029563137 scopus 로고
    • Docetaxel (Taxotere): An effective agent in the management of second-line breast cancer
    • (1995) Semin Oncol , vol.22 , pp. 22-28
    • Van Oosterom, A.T.1
  • 48
    • 0031040149 scopus 로고    scopus 로고
    • The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents
    • (1997) Annu Rev Med , vol.48 , pp. 353-374
    • Rowinsky, E.K.1
  • 51
    • 0033863452 scopus 로고    scopus 로고
    • Phase 1 and pharmacokinetic study of a new taxoid, RPR 109881 A, given as a 1-hour intravenous infusion in patients with advanced solid tumors
    • (2000) J Clin Oncol , vol.18 , pp. 3164-3171
    • Kurata, T.1    Shimada, Y.2    Tamura, T.3
  • 57
    • 0030018666 scopus 로고    scopus 로고
    • Epothilons A and B: Antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physico-chemical and biological properties
    • (1996) J Antibiot , vol.49 , pp. 560-563
    • Gerth, K.1    Bedorf, N.2    Hofle, G.3
  • 60
    • 0030761974 scopus 로고    scopus 로고
    • Epothilone B stabilizes microtubuli of macrophages like taxol without showing taxol-like endotoxin activity
    • (1997) Cancer Res , vol.57 , pp. 3344-3346
    • Muhlradt, P.F.1    Sasse, F.2
  • 65
    • 0034199809 scopus 로고    scopus 로고
    • On the total synthesis and preliminary biological evaluations of 15(R) and 15(S) aza-dEpoB: A Mitsunobu inversion at C 15 in pre-epothilone fragments
    • (2000) Org Lett , vol.2 , pp. 1637-1639
    • Stachel, S.J.1    Chappell, M.D.2    Lee, C.B.3
  • 73
    • 0034939512 scopus 로고    scopus 로고
    • The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: Curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8113-8118
    • Chou, T.C.1    O'Connor, O.A.2    Tong, W.P.3
  • 74
    • 0033609037 scopus 로고    scopus 로고
    • The coral-derived natural products eleutherobin and sarcodictyins A and B: Effects on the assembly of purified tubulin with and without microtubule associated proteins and binding at the polymer taxoid site
    • (1999) Biochemistry , vol.38 , pp. 5490-5498
    • Hamel, E.1    Sackett, D.L.2    Vourloumis, D.3
  • 81
    • 0030113284 scopus 로고    scopus 로고
    • (+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest
    • (1996) Chem Biol , vol.3 , pp. 287-293
    • Hung, D.T.1    Chen, J.2    Schreiber, S.L.3
  • 82
    • 0030761586 scopus 로고    scopus 로고
    • The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells
    • (1997) Mol Pharmacol , vol.52 , pp. 613-622
    • Kowalski, R.J.1    Giannakakou, P.2    Gunasekera, S.P.3
  • 98
    • 10144251769 scopus 로고    scopus 로고
    • Syntheses and structure-activity relationships of the second-generation antitumor taxoids: Exceptional activity against drug-resistant cancer cells
    • (1996) J Med Chem , vol.39 , pp. 3889-3896
    • Ojima, I.1    Slater, J.C.2    Michaud, E.3
  • 100
    • 0032101105 scopus 로고    scopus 로고
    • Complete regression of well-established tumors using a novel water-soluble poly(L-glutamic acid)-paclitaxel conjugate
    • (1998) Cancer Res , vol.58 , pp. 2404-2409
    • Li, C.1    Yu, D.F.2    Newman, R.A.3
  • 102
    • 0033629139 scopus 로고    scopus 로고
    • Comparison of action of paclitaxel and poly(L-glutamic acid)-paclitaxel conjugate in human breast cancer cell
    • (2000) Int J Oncol , vol.16 , pp. 125-132
    • Oldham, E.A.1    Li, C.2    Ke, S.3
  • 106
    • 0034234649 scopus 로고    scopus 로고
    • Polymeric micellar paclitaxel phosphorylates Bcl-2 and induces apoptotic regression of androgen-independent LNCaP prostate tumors
    • (2000) Prostate , vol.44 , pp. 156-163
    • Leung, S.Y.1    Jackson, J.2    Miyake, H.3
  • 109


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.