Paclitaxel-resistant human ovarian cancer cells have mutant β-tubulins that exhibit impaired paclitaxel-driven polymerization

Journal of Biological Chemistry

Volumn 272, Issue 27, 1997, Pages 17118-17125

  Giannakakou, Paraskevi ^a   Sackett, Dan L ^a   Kang, Yoon Koo ^b   Zhan, Zhirong ^a   Buters, Jeroen T M ^a   Fojo, Tito ^a   Poruchynsky, Marianne S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Korea Cancer Center Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TUBULIN; EPOTHILONE B; GLYCOPROTEIN P; MESSENGER RNA; PACLITAXEL; VERAPAMIL; VINBLASTINE;

ANIMAL TISSUE; ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG PROTEIN BINDING; FEMALE; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; NONHUMAN; OVARY CARCINOMA; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALIA;

EID: 0030758777     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.27.17118     Document Type: Article

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