Desoxyepothilone B: An efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 16, 1998, Pages 9642-9647

  Chou, Ting Chao ^a,b   Zhang, Xiu Guo ^a   Balog, Aaron ^a   Su, Dai Shi ^a   Meng, Dongfang ^a   Savin, Kenneth ^a   Bertino, Joseph R ^a,b   Danishefsky, Samuel J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; DACTINOMYCIN; DESOXYEPOTHILONE B; DOXORUBICIN; EPOTHILONE A; EPOTHILONE B; ETOPOSIDE; MACROLIDE; PACLITAXEL; UNCLASSIFIED DRUG; VINBLASTINE; VINBLASTINE SULFATE;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ELECTRON MICROSCOPY; HAMSTER; HUMAN; HUMAN CELL; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MICROTUBULE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TUMOR REGRESSION; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG RESISTANCE, NEOPLASM; EPOTHILONES; HUMANS; LACTONES; MICE; MICE, NUDE; MICROTUBULES; NEOPLASM TRANSPLANTATION; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TUMOR CELLS, CULTURED;

ANIMALIA; CRICETINAE; MINK CELL FOCUS-FORMING VIRUS; MUS MUSCULUS; RODENTIA;

EID: 0032483019     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.16.9642     Document Type: Article

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