메뉴 건너뛰기




Volumn 26, Issue 10, 2001, Pages 985-998

VLA-4 antagonists

Author keywords

[No Author keywords available]

Indexed keywords

2,6 DICHLOROBENZYL ETHER; 3 FLUOROPROLINOL; AZACYCLOBUTYL BIPHENYLALANINE; BENZOXAZOLE DERIVATIVE; BETA1 INTEGRIN; BIO 1211; BIO 1272; CARBANILAMIDE; CARBONYL DERIVATIVE; CT 5219; CT 757; CT 767; CY 9607; CY 9701; CYCLOPEPTIDE; HYDANTOIN DERIVATIVE; IVL 745; N BENZYLPYROGLUTAMYL DERIVATIVE; NATALIZUMAB; PHENOXYACYLLEUCYLPHENYLALANINE DERIVATIVE; PHENYLSULFONYL BIPHENYLALANINE; PROBUCOL SUCCINATE; PROTEIN INHIBITOR; SB 683698; SQUARIC ACID DERIVATIVE; TBC 3342; TBC 3486; TR 14035; TR 9109; UNCLASSIFIED DRUG; UNINDEXED DRUG; UREA DERIVATIVE; ZD 7349;

EID: 0035655590     PISSN: 03778282     EISSN: None     Source Type: Journal    
DOI: 10.1358/dof.2001.026.10.858716     Document Type: Review
Times cited : (24)

References (115)
  • 6
    • 0029046132 scopus 로고
    • The crystal structure of an N-terminal two domain fragment of vascular cell adhesion molecule 1 (VCAM-1): A cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1 α-4 integrin interaction
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5714-5718
    • Wang, J.H.1    Pepinsky, R.B.2    Stehle, T.3
  • 8
    • 0025777183 scopus 로고
    • The minimal essential sequence for a major cell type-specific adhesion site (CS-1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine
    • (1991) J Biol Chem , vol.266 , pp. 15075-15079
    • Komoriya, A.1    Green, I.J.2    Mervic, M.3
  • 10
    • 0035918153 scopus 로고    scopus 로고
    • 1 integrin binding sites within a 38 amino acid domain in the N-terminal thrombin fragment of human osteopontin
    • (2001) J Biol Chem , vol.276 , pp. 13483-13489
    • Bayless, K.J.1    Davis, G.E.2
  • 16
    • 0035805633 scopus 로고    scopus 로고
    • Association of the membrane proximal regions of the α and β subunit cytoplasmic domains constrains an integrin in the inactive state
    • (2001) J Biol Chem , vol.276 , pp. 14642-14648
    • Lu, C.1    Takagi, J.2    Springer, T.A.3
  • 39
    • 0007386201 scopus 로고    scopus 로고
    • AtheroGenics Press Release
  • 47
    • 0030474803 scopus 로고    scopus 로고
    • Protective effects of monoclonal antibody to VLA-4 on leukocyte adhesion and course of disease in adjuvant arthritis in rats
    • (1996) J Rheumatol , vol.23 , pp. 2086-2091
    • Seiffge, D.1
  • 70
    • 0000219331 scopus 로고    scopus 로고
    • A randomized double-blind, placebo-controlled, pan-European study of a recombinant humanized antibody to α-4 integrin (Antegren®) in moderately to severe active Crohn's disease
    • (2001) Gastroenterology , vol.120 , Issue.SUPPL. 1
    • Ghosh, S.1    Goldin, E.2    Malchow, H.A.3
  • 77
    • 0033824604 scopus 로고    scopus 로고
    • 1 integrin)-mediated cell adhesion. Discovery of compounds like cyclo(MePhe-LeuAsp-Val-dArg-dArg) (ZD7349) compatible with depot formulation
    • (2000) J Pept Sci , vol.6 , pp. 398-412
    • Dutta, A.S.1    Gormley, J.J.2    Coath, M.3
  • 78
    • 0033943476 scopus 로고    scopus 로고
    • Potent cyclic monomeric and dimeric peptide inhibitors of VLA-4 (α-4 β-1 integrin)-mediated cell adhesion based on the lle-Leu-Asp-Val tetrapeptide
    • (2000) J Pept Sci , vol.6 , pp. 321-341
    • Dutta, A.S.1    Mandy, C.2    Gormley, J.J.3
  • 82
    • 0007416653 scopus 로고    scopus 로고
    • SAR studies of the leucine portion of Bio-1050, a potent and selective nanomolar antagonist of the integrin VLA-4 (α-4 β-1)
    • (April 13-17, San Francisco), Abst MEDI 076
    • (1997) 213th ACS Natl Meet
    • Zimmerman, C.N.1    Lin, K.-C.2
  • 90
    • 0007425394 scopus 로고    scopus 로고
    • Non-peptidyl inhibitors of VLA-4 dependent cell binding useful in treating inflammatory autoimmune and respiratory diseases. WO 0000477
    • Duplantier, A.J.1    Milici, A.J.2
  • 93
  • 111
    • 0007431409 scopus 로고    scopus 로고
    • (American Home Products Corp.). 3,4-Diamino-3-cyclo-butene-1,2-dione derivatives which inhibit leukocyte adhesion mediated by VLA-4. US 6166050
    • Lombardo, L.J.1    Sabalski, H.2
  • 113
    • 0007383357 scopus 로고    scopus 로고
    • GlaxoSmithKline Corporate Web Site


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.