Potent α4β1 peptide antagonists as potential anti-inflammatory agents

Journal of Medicinal Chemistry

Volumn 40, Issue 21, 1997, Pages 3359-3368

  Jackson, David Y ^a   Quan, Clifford ^a   Artis, Dean R ^a   Rawson, Thomas ^a   Blackburn, Brent ^a   Struble, Martin ^a   Fitzgerald, Geraldine ^a   Chan, Kathryn ^a   Mullins, Sheldon ^a   Burnier, J P ^a   Fairbrother, Wayne J ^a   Clark, Kevin ^a   Berisini, Maureen ^a   Chui, Henry ^a   Renz, Mark ^a   Jones, Susan ^a   Fong, Sherman ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; FIBRONECTIN; INTEGRIN; INTEGRIN ADHESION RECEPTOR ALPHA4 BETA1; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; INFLAMMATION; INTRAVENOUS DRUG ADMINISTRATION; LEUKOCYTE ADHERENCE; LYMPHOCYTE HOMING; LYMPHOCYTE MIGRATION; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PEPTIDE SYNTHESIS; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; CELL ADHESION; CELL MOVEMENT; INTEGRIN ALPHA4BETA1; INTEGRINS; LYMPHOCYTES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PEPTIDES, CYCLIC; RECEPTORS, LYMPHOCYTE HOMING; STRUCTURE-ACTIVITY RELATIONSHIP; VASCULAR CELL ADHESION MOLECULE-1;

EID: 9844223916     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970175s     Document Type: Article

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