-
1
-
-
0026770377
-
Integrins: Versatility, modulation, and signaling in cell adhesion
-
Hynes R.O. Integrins: versatility, modulation, and signaling in cell adhesion. Cell. 69:1992;11-25.
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes, R.O.1
-
2
-
-
0010256377
-
Structure, function and modulation of E-cadherins as mediators of cell-cell adhesion
-
Lutz K.L.et al. Structure, function and modulation of E-cadherins as mediators of cell-cell adhesion. Curr. Top. Pept. Protein Res. 2:1997;69-82.
-
(1997)
Curr. Top. Pept. Protein Res.
, vol.2
, pp. 69-82
-
-
Lutz, K.L.1
-
3
-
-
0032904627
-
Mechanisms that regulate the function of the selectins and their ligands
-
Vestweber D., Blanks J.E. Mechanisms that regulate the function of the selectins and their ligands. Physiol. Rev. 79:1999;181-213.
-
(1999)
Physiol. Rev.
, vol.79
, pp. 181-213
-
-
Vestweber, D.1
Blanks, J.E.2
-
4
-
-
0025182959
-
Adhesion receptors of the immune system
-
Springer T.A. Adhesion receptors of the immune system. Nature. 346:1990;425-434.
-
(1990)
Nature
, vol.346
, pp. 425-434
-
-
Springer, T.A.1
-
5
-
-
0027459771
-
Signal transduction from the extracellular matrix
-
Juliano R.L., Haskill S. Signal transduction from the extracellular matrix. J. Cell Biol. 120:1993;577-585.
-
(1993)
J. Cell Biol.
, vol.120
, pp. 577-585
-
-
Juliano, R.L.1
Haskill, S.2
-
6
-
-
0029164237
-
Integrin transmembrane signaling and cytoskeletal control
-
Yamada K.M., Miyamoto S. Integrin transmembrane signaling and cytoskeletal control. Curr. Opin. Cell Biol. 7:1995;681-689.
-
(1995)
Curr. Opin. Cell Biol.
, vol.7
, pp. 681-689
-
-
Yamada, K.M.1
Miyamoto, S.2
-
7
-
-
0032911020
-
Bidirectional signaling between the cytoskeleton and integrins
-
Schoenwaelder S.M., Burridge K. Bidirectional signaling between the cytoskeleton and integrins. Curr. Opin. Cell Biol. 11:1999;274-286.
-
(1999)
Curr. Opin. Cell Biol.
, vol.11
, pp. 274-286
-
-
Schoenwaelder, S.M.1
Burridge, K.2
-
8
-
-
0032907102
-
Integrins and signal transduction
-
Dedhar S. Integrins and signal transduction. Curr. Opin. Hematol. 6:1999;37-43.
-
(1999)
Curr. Opin. Hematol.
, vol.6
, pp. 37-43
-
-
Dedhar, S.1
-
9
-
-
0031964022
-
Cell migration: Regulation of force on extracellular-matrix-integrin complexes
-
Sheetz M.P.et al. Cell migration: regulation of force on extracellular-matrix-integrin complexes. Trends Cell Biol. 8:1998;51-54.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 51-54
-
-
Sheetz, M.P.1
-
12
-
-
0028987190
-
Cooperative signaling by α5β1 and α4β1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin
-
Huhtala P.et al. Cooperative signaling by α5β1 and α4β1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin. J. Cell Biol. 129:1995;867-879.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 867-879
-
-
Huhtala, P.1
-
13
-
-
0025602916
-
The molecular basis and specificity of integrin-ligand interactions
-
Humphries M.J. The molecular basis and specificity of integrin-ligand interactions. J. Cell Sci. 97:1990;585-592.
-
(1990)
J. Cell Sci.
, vol.97
, pp. 585-592
-
-
Humphries, M.J.1
-
14
-
-
0028924936
-
Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 Å resolution
-
Jones E.Y.et al. Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 Å resolution. Nature. 373:1995;539-544.
-
(1995)
Nature
, vol.373
, pp. 539-544
-
-
Jones, E.Y.1
-
15
-
-
0030050396
-
2.0 Å crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region
-
Leahy D.J.et al. 2.0 Å crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region. Cell. 84:1996;155-164.
-
(1996)
Cell
, vol.84
, pp. 155-164
-
-
Leahy, D.J.1
-
16
-
-
0024292679
-
Site-directed mutagenesis of the cell-binding domain of human fibronectin: Separable, synergistic sites mediate adhesive function
-
Obara M.et al. Site-directed mutagenesis of the cell-binding domain of human fibronectin: separable, synergistic sites mediate adhesive function. Cell. 53:1988;649-657.
-
(1988)
Cell
, vol.53
, pp. 649-657
-
-
Obara, M.1
-
18
-
-
0028054340
-
A secondary structure model of the integrin α subunit N-terminal domain based on analysis of multiple alignments
-
Tuckwell D.S.et al. A secondary structure model of the integrin α subunit N-terminal domain based on analysis of multiple alignments. Cell Adhes. Commun. 2:1994;385-402.
-
(1994)
Cell Adhes. Commun.
, vol.2
, pp. 385-402
-
-
Tuckwell, D.S.1
-
19
-
-
0031013031
-
Folding of the N-terminal, ligand-binding region of integrin α-subunits into a β-propeller domain
-
Springer T.A. Folding of the N-terminal, ligand-binding region of integrin α-subunits into a β-propeller domain. Proc. Natl. Acad. Sci. U. S. A. 94:1997;65-72.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 65-72
-
-
Springer, T.A.1
-
20
-
-
0028986196
-
Crystal structure of the A domain from the α subunit of integrin CR3 (CD11b/CD18)
-
Lee J.O.et al. Crystal structure of the A domain from the α subunit of integrin CR3 (CD11b/CD18). Cell. 80:1995;631-638.
-
(1995)
Cell
, vol.80
, pp. 631-638
-
-
Lee, J.O.1
-
21
-
-
0031029272
-
A structure prediction for the ligand-binding region of the integrin β subunit: Evidence for the presence of a von Willebrand factor A domain
-
Tuckwell D.S., Humphries M.J. A structure prediction for the ligand-binding region of the integrin β subunit: evidence for the presence of a von Willebrand factor A domain. FEBS Lett. 400:1997;297-303.
-
(1997)
FEBS Lett.
, vol.400
, pp. 297-303
-
-
Tuckwell, D.S.1
Humphries, M.J.2
-
22
-
-
0029786892
-
Ligand binding to integrin αiIbβ3 is dependent on a MIDAS-like domain in the β3 subunit
-
Tozer E.C.et al. Ligand binding to integrin αIIbβ3 is dependent on a MIDAS-like domain in the β3 subunit. J. Biol. Chem. 271:1996;21978-21984.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 21978-21984
-
-
Tozer, E.C.1
-
23
-
-
0031974042
-
The structure of cell-adhesion molecules
-
Humphries M.J., Newham P. The structure of cell-adhesion molecules. Trends Cell Biol. 8:1998;78-83.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 78-83
-
-
Humphries, M.J.1
Newham, P.2
-
24
-
-
0027248518
-
Identification of a regulatory region of integrin β1 subunit using activating and inhibiting antibodies
-
Takada Y., Puzon W. Identification of a regulatory region of integrin β1 subunit using activating and inhibiting antibodies. J. Biol. Chem. 268:1993;17597-17601.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17597-17601
-
-
Takada, Y.1
Puzon, W.2
-
25
-
-
0028805249
-
Critical amino acid residues for ligand binding are clustered in a predicted β-turn of the third N-terminal repeat in the integrin α4 and α5 subunits
-
Irie A.et al. Critical amino acid residues for ligand binding are clustered in a predicted β-turn of the third N-terminal repeat in the integrin α4 and α5 subunits. EMBO J. 14:1995;5550-5556.
-
(1995)
EMBO J.
, vol.14
, pp. 5550-5556
-
-
Irie, A.1
-
26
-
-
0024280898
-
Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor
-
D'Souza S.E.et al. Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor. Science. 242:1988;91-93.
-
(1988)
Science
, vol.242
, pp. 91-93
-
-
D'Souza, S.E.1
-
27
-
-
0024230916
-
The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the β subunit
-
Smith J.W., Cheresh D.A. The Arg-Gly-Asp binding domain of the vitronectin receptor. Photoaffinity cross-linking implicates amino acid residues 61-203 of the β subunit. J. Biol. Chem. 263:1988;18726-18731.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 18726-18731
-
-
Smith, J.W.1
Cheresh, D.A.2
-
28
-
-
0030272101
-
Integrin activation: The link between ligand binding and signal transduction
-
Humphries M.J. Integrin activation: the link between ligand binding and signal transduction. Curr. Opin. Cell Biol. 8:1996;632-640.
-
(1996)
Curr. Opin. Cell Biol.
, vol.8
, pp. 632-640
-
-
Humphries, M.J.1
-
29
-
-
0029969086
-
Getting integrins into shape: Recent insights into how integrin activity is regulated by conformational changes
-
Mould A.P. Getting integrins into shape: recent insights into how integrin activity is regulated by conformational changes. J. Cell Sci. 109:1996;2613-2618.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 2613-2618
-
-
Mould, A.P.1
-
30
-
-
0029646107
-
Two conformations of the integrin A-domain (I-domain): A pathway for activation?
-
Lee J.O.et al. Two conformations of the integrin A-domain (I-domain): a pathway for activation? Structure. 3:1995;1333-1340.
-
(1995)
Structure
, vol.3
, pp. 1333-1340
-
-
Lee, J.O.1
-
31
-
-
0031569914
-
New insights into integrin-ligand interaction
-
Loftus J.C., Liddington R.C. New insights into integrin-ligand interaction. J. Clin. Invest. 99:1997;2302-2306.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2302-2306
-
-
Loftus, J.C.1
Liddington, R.C.2
-
32
-
-
0032079781
-
Regulation of integrin function: Evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin α5β1
-
Mould A.P.et al. Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin α5β1. Biochem. J. 331:1998;821-828.
-
(1998)
Biochem. J.
, vol.331
, pp. 821-828
-
-
Mould, A.P.1
-
33
-
-
0029664954
-
The inhibitory anti-β1 integrin monoclonal antibody 13 recognizes an epitope that is attenuated by ligand occupancy. Evidence for allosteric inhibition of integrin function
-
Mould A.P.et al. The inhibitory anti-β1 integrin monoclonal antibody 13 recognizes an epitope that is attenuated by ligand occupancy. Evidence for allosteric inhibition of integrin function. J. Biol. Chem. 271:1996;20365-20374.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20365-20374
-
-
Mould, A.P.1
-
34
-
-
0032080651
-
Analysis of ligand-induced and ligand-attenuated epitopes on the leukocyte integrin α4β1: VCAM-1, mucosal addressin cell adhesion molecule-1, and fibronectin induce distinct conformational changes
-
Newham P.et al. Analysis of ligand-induced and ligand-attenuated epitopes on the leukocyte integrin α4β1: VCAM-1, mucosal addressin cell adhesion molecule-1, and fibronectin induce distinct conformational changes. J. Immunol. 160:1998;4508-4517.
-
(1998)
J. Immunol.
, vol.160
, pp. 4508-4517
-
-
Newham, P.1
-
35
-
-
0030798854
-
Defining the topology of integrin α5β1-fibronectin interactions using inhibitory anti-α5 and anti-β1 monoclonal antibodies. Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the α5 subunit
-
Mould A.P.et al. Defining the topology of integrin α5β1-fibronectin interactions using inhibitory anti-α5 and anti-β1 monoclonal antibodies. Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the α5 subunit. J. Biol. Chem. 272:1997;17283-17292.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17283-17292
-
-
Mould, A.P.1
-
36
-
-
0033406615
-
Fine mapping of inhibitory anti-α5 monoclonal antibody epitopes that differentially affect integrin-ligand binding
-
(in press)
-
Burrows L.et al. Fine mapping of inhibitory anti-α5 monoclonal antibody epitopes that differentially affect integrin-ligand binding. Biochem J. 1999;. (in press).
-
(1999)
Biochem J.
-
-
Burrows, L.1
-
37
-
-
0032574691
-
Experimental support for a β-propeller domain in integrin α-subunits and a calcium binding site on its lower surface
-
Oxvig C., Springer T.A. Experimental support for a β-propeller domain in integrin α-subunits and a calcium binding site on its lower surface. Proc. Natl. Acad. Sci. U. S. A. 95:1998;870-4875.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 870-4875
-
-
Oxvig, C.1
Springer, T.A.2
-
38
-
-
0028354543
-
Integrin antagonists as modulators of adhesion
-
Humphries M.et al. Integrin antagonists as modulators of adhesion. Expert Opin. Ther. Pat. 4:1994;227-235.
-
(1994)
Expert Opin. Ther. Pat.
, vol.4
, pp. 227-235
-
-
Humphries, M.1
-
39
-
-
0030999134
-
Platelet GPIIb/IIIa antagonists: The first anti-integrin receptor therapeutics
-
Coller B.S. Platelet GPIIb/IIIa antagonists: the first anti-integrin receptor therapeutics. J. Clin. Invest. 99:1997;1467-1471.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 1467-1471
-
-
Coller, B.S.1
-
40
-
-
0001769481
-
Blockade of the VLA-4 integrin as a therapy for airway inflammation in respiratory disease
-
Elices M.J. Blockade of the VLA-4 integrin as a therapy for airway inflammation in respiratory disease. Curr. Opin. Anti-Inflammatory Immunomodulatory Invest. Drugs. 1:1999;14-20.
-
(1999)
Curr. Opin. Anti-Inflammatory Immunomodulatory Invest. Drugs
, vol.1
, pp. 14-20
-
-
Elices, M.J.1
-
41
-
-
0342632392
-
Update on glycoprotein IIb/IIIa inhibitors
-
Subbarao V.et al. Update on glycoprotein IIb/IIIa inhibitors. Curr. Opin. Cardiovasc. 1:1999;56-62.
-
(1999)
Curr. Opin. Cardiovasc.
, vol.1
, pp. 56-62
-
-
Subbarao, V.1
-
42
-
-
0033121275
-
The role of αv integrins during angiogenesis: Insights into potential mechanisms of action and clinical development
-
Eliceiri B.P., Cheresh D.A. The role of αV integrins during angiogenesis: insights into potential mechanisms of action and clinical development. J. Clin. Invest. 103:1999;1227-1230.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1227-1230
-
-
Eliceiri, B.P.1
Cheresh, D.A.2
|