Multiple activation states of integrin α4β1 detected through their different affinities for a small molecule ligand

Journal of Biological Chemistry

Volumn 274, Issue 19, 1999, Pages 13167-13175

  Chen, Ling Ling ^a   Whitty, Adrian ^a   Lobb, Roy R ^a   Adams, Steven P ^a   Pepinsky, R Blake ^a  

^a BIOGEN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN;

ALTERNATIVE RNA SPLICING; ARTICLE; BINDING SITE; CELL INTERACTION; COMPETITIVE INHIBITION; COMPLEX FORMATION; CRYSTALLIZATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIGAND BINDING; PRIORITY JOURNAL; RECEPTOR AFFINITY;

EID: 0000678946     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.19.13167     Document Type: Article

References (44)

1. Hynes, R. O. (1992) Cell 69, 11-25
2. Ruoshlahti, E. (1991) J. Clin. Invest. 87, 1-5
3. Hemler, M. E., Elices, M. J., Parker, C., and Takada, Y. (1990) Immunol. Rev. 114, 45-65
4. Lobb, R. R., and Hemler, M. E. (1994) J. Clin. Invest. 94, 1722-1728
5. Springer, T. A. (1994) Cell 76, 301-314
6. Damle, N. K., and Aruffo, A. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 6403-6407
7. Anwar, A. R., Walsh, G. M., Cromwell, O., Kay, A. B., and Wardlaw, A. J. (1994) Immunology 82, 222-228
8. Clark, E. A., and Brugge, J. S. (1995) Science 268, 233-239
9. Udagawa, T., Woodside, D. G., and McIntyre, B. W. (1996) J. Immunol. 157, 1965-1972
10. Yoshikawa, H., Sakihama, T., Nakajima, Y., and Tasaka, K. (1996) J. Immunol. 156, 1832-1840
11. Ferguson, T. A., Mizutani, H., and Kupper, T. S. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 8072-8076
12. Wahl, S. M., Allen, J. B., Hines, K. L., Imamichi, T., Wahl, A. M., Furcht, L. T., and McCarthy, J. B. (1994) J. Clin. Invest. 94, 655-662
13. Molossi, S., Elices, M., Arrhenius, T., Diaz, R., Coulber, C., and Rabinovitch, M. (1995) J. Clin. Invest. 95, 2601-2610
14. Osborn, L., Hession, C., Tizard, R., Vassalio, C., Luhowskyj, S., Chi-Rosso, G., and Lobb, R. (1989) Cell 59, 1203-1211
15. Elices, M. J., Osborn, L., Takada, Y., Crouse, C., Luhowskyj, S., Hemler, M. E., and Lobb, R. R. (1990) Cell 60, 577-584
16. Wayner, E. A., Garcia-Pardo, A., Humphries, M. J., McDonald, J. A., and Carter, W. G. (1989) J. Cell Biol. 109, 1321-1330
17. Guan, J. L., and Hynes, R. O. (1990) Cell 60, 53-61
18. Chan, B. M. C., Wong, J. G. P., Rao, A., and Hemler, M. E. (1991) J. Immunol. 147, 398-404
19. Shimizu, Y., VanSeventer, G. A., Horgan, K. J., and Shaw, S. (1990) Nature 345, 250-253
20. Masumoto, A., and Hemler, M. E. (1993) J. Biol. Chem. 268, 228-234
21. Humphries, M. J. (1996) Curr. Opin. Cell Biol. 8, 632-640
22. Hu, D. D., Barbas, C. F., III and Smith, J. W. (1996) J. Biol. Chem. 271, 21745-21751
23. Gulino, D., Boudignon, C., Zhang, L., Concord, E., Rabiet, M.-J., and Margue, G. (1992) J. Biol. Chem. 267, 1001-1007
24. Springer, T. A. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 65-72
25. Irie, A., Kamata, T., and Takada, Y. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 7198-7203
26. Corbi, A. L., Miller, L. J., O'Conner, K., Larson, R. S., and Springer, T. A. (1987) EMBO J. 6, 4023-4028
27. Tuckwell, D. S., and Humphries, M. J. (1997) FEBS Lett. 400, 297-303
28. Lee, J.-O., Rieu, P., Arnaout, A., and Liddington, R. (1995) Cell 80, 631-638
29. Qu, A., and Leahy, D. J. (1996) Structure 4, 931-942
30. Emsley, J., King, S. L., Bergelson, J. M., and Liddington, R. C. (1997) J. Biol. Chem. 272, 28512-28517
31. Mould, A. P., Akiyama, S. K., and Humphries, M. J. (1995) J. Biol. Chem. 270, 26270-26277
32. Chen, L. L., Lobb, R. R., Cuervo, J. H., Adams, S. P., and Pepinsky, R. B. (1998) Biochemistry 37, 8743-8753
33. Wang, J.-H., Pepinsky, B., Stehle, T., Liu, J.-H., Karpusas, M., Browning, B., and Osborn, L. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5714-5718
34. Wayer, E. A., and Kovach, N. L. (1992) J. Cell Biol. 116, 489-497
35. Lin, K.-C., Ateeq, H. S., Lee, W.-C., Zimmerman C. N., Castro, A., Hammond, C., Kalkunte, S., Chen, L. L., Pepinsky, R. B., Leone, D. E., Sprague, A. G., Abraham, W. M., Gill, A., Lobb, R. R., and Adams, S. P. (1998) J. Med. Chem., 42, 920-934
36. Lobb, R. R., Antognetti, G., Pepinsky, R. B., Burkly, L., Leone, D., and Whitty, A (1995) Cell Adhes. Commun. 3, 385-397
37. Bazzoni, G., Ma, L., Blue, M.-L., and Hemler, M. E. (1998) J. Biol. Chem. 273, 6670-6678
38. Jakubowski, A., Rosa, M. D., Bixler, S., Lobb, R., and Burkly, L. C. (1995) Cell Adh. Commun. 3, 131-142
39. Perelson, A. S., and DeLisi, C. (1980) Math. Biosci. 48, 71-110
40. D'Souza, S. E., Haas, T. A., Piotrowics, R. S., Byers-Ward, V., McGrath, D. E., Soule, H. R., Cierniewski, C., Plow, E. F., and Smith, J. W. (1994) Cell 79, 659-667
41. Irie, A., Kamata, T., Puzon-McLaughlin, W., and Takada, Y. (1995) EMBO J. 14, 5550-5556
42. Newham, P., Craig, S. E., Clark, K., Mould, A. P., and Humphries, M. J. (1998) J. Immunol. 160, 4508-4517
43. Lobb, R. R., Chi-Rosso, G., Leone, D., Rosa, M., Newman, B., Luhowshyj, S., Osborn, L., Schiffer, S., Benjamin, C., Dougaa, I., Hession, C., and Chow, E. P. (1991) Biochem. Biophys. Res. Commun. 178, 1498-1504
44. Masumoto, A., and Hemler, M. E. (1993) J. Biol. Chem. 268, 228-234