N-benzylpyroglutamyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 8, 2000, Pages 729-733

  Chen, Li ^a   Tilley, Jefferson W ^a   Guthrie, Robert W ^a   Mennona, Francis ^a   Huang, Tai Nan ^a   Kaplan, Gerry ^a   Trilles, Richard ^a   Miklowski, Dorota ^a   Huby, Nicolas ^a   Schwinge, Virginia ^a   Wolitzky, Barry ^a   Rowan, Karen ^a  

^a HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZAMIDE; BETA1 INTEGRIN; N BENZYLPYROGLUTAMYL L PHENYLALANINE DERIVATIVE; PHENYLALANINE; PHENYLALANINE DERIVATIVE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ACYLATION; ARTICLE; CHEMICAL MODIFICATION; DRUG STRUCTURE; HUMAN; INHIBITION KINETICS; PARTIAL DRUG SYNTHESIS; RECEPTOR BLOCKING; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

CELL LINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTEGRIN ALPHA4BETA1; INTEGRINS; PHENYLALANINE; RECEPTORS, LYMPHOCYTE HOMING; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0034678785     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00089-5     Document Type: Article

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