Epothilone biosynthesis: Assembly of the methylthiazolylcarboxy starter unit on the EpoB subunit

Chemistry and Biology

Volumn 8, Issue 9, 2001, Pages 899-912

  Chen, Huawei ^a   O'Connor, Sarah ^a   Cane, David E ^b   Walsh, Christopher T ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

Epothilone biosynthesis; Non ribosomal peptide synthetase; Polyketide synthase; Polyketide synthase non ribosomal peptide synthetase hybrid

Indexed keywords

ACYL CARRIER PROTEIN; ACYL COENZYME A; ANTINEOPLASTIC AGENT; CHEMICAL STRUCTURE; EPOTHILONE DERIVATIVE; ESCHERICHIA COLI; MACROLIDE; METHYLTHIAZOLYLCARBOXY S EPOB; NATURAL PRODUCT; PEPTIDE; PHOSPHOPANTETHEINYL TRANSFERASE; POLYKETIDE SYNTHASE; POLYKETIDE; REACTION MECHANISM; SORANGIUM CELLULOSUM; THIOTEMPLATE MECHANISM;

ACYL COENZYME A; ANTINEOPLASTIC AGENTS; CARRIER PROTEINS; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EPOTHILONES; ESCHERICHIA COLI; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MACROLIDES; MULTIENZYME COMPLEXES;

ESCHERICHIA COLI; POLYANGIUM CELLULOSUM; SORANGIUM;

EID: 0034837369     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(01)00064-3     Document Type: Article

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