The role of neuronal and extraneuronal plasma membrane transporters in the inactivation of peripheral catecholamines

Pharmacology and Therapeutics

Volumn 91, Issue 1, 2001, Pages 35-62

  Eisenhofer, Graeme ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Dopamine; Epinephrine; Norepinephrine; Sympathetic nervous system; Transporter; Uptake

Indexed keywords

CATECHOLAMINE DERIVATIVE; CORTICOSTERONE; DOPAMINE TRANSPORTER; MONOAMINE; NORADRENALIN TRANSPORTER;

BODY REGIONS; CATECHOLAMINE METABOLISM; CATECHOLAMINE RELEASE; CATECHOLAMINE SYNTHESIS; CATECHOLAMINE UPTAKE; CELL MEMBRANE; CELL MEMBRANE TRANSPORT; CLINICAL IMMUNOLOGY; CONGESTIVE HEART FAILURE; DOPAMINERGIC NERVE CELL; ENDOTHELIUM CELL; HUMAN; HYPERTENSION; IMAGING; NEUROBLASTOMA; NEUROTRANSMITTER RELEASE; NONHUMAN; NORADRENERGIC NERVE; PHEOCHROMOCYTOMA; PLASMA CLEARANCE; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SYNCYTIOTROPHOBLAST; TISSUE DISTRIBUTION;

CARRIER PROTEINS; CATECHOLAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; CATECHOLAMINES; HEART FAILURE, CONGESTIVE; HUMANS; HYPERTENSION; MEMBRANE TRANSPORT PROTEINS; NEURONS; POLYMORPHISM, GENETIC;

EID: 0035156972     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(01)00144-9     Document Type: Review

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235. Adrenergic receptors in adipose tissue and their relation to adrenergic innervation
236. Phenotypic evidence of faulty neuronal norepinephrine reuptake in essential hypertension
237. Increased cardiac adrenergic drive precedes generalized sympathetic activation in human heart failure
238. Pharmacological properties of naturally occurring variants of the human norepinephrine transporter
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251. Scintigraphic localization of pheochromocytoma
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254. Regional differences in H3-norepinephrine and H3-dopamine uptake into rat brain homogenates
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256. Renal tubular dopamine outward transfer during Na(+)-H+ exchange activation by alpha 1- and alpha 2-adrenoceptor agonists
257. Studies on the role of sodium on the synthesis of dopamine in the rat kidney
258. Involvement of tubular sodium in the formation of dopamine in the human renal cortex
259. Quantitation of myocardial iodine-123 MIBG uptake in SPET studies: A new approach using the left ventricular cavity and a blood sample as a reference
260. Increased myocardial [123I]-metaiodobenzylguanidine uptake after enalapril treatment in patients with chronic heart failure
261. Nerve activity-dependent variations in clearance of released noradrenaline: Regulatory roles for sympathetic neuromuscular transmission in rat tail artery
262. Systematic search for variation in the human norepinephrine transporter gene: Identification of five naturally occurring missense mutations and study of association with major psychiatric disorders
263. A cognate dopamine transporter-like activity endogenously expressed in a COS-7 kidney-derived cell line
264. Norepinephrine uptake by rat jejunum: Modulation by angiotensin II
265. Basolateral localization of organic cation transporter 2 in intact renal proximal tubules
266. Peripheral presynaptic facilitatory effect of angiotensin II on noradrenaline release in anesthetized rabbits
267. Rudolf Buchheim lecture. The metabolizing systems involved in the inactivation of catecholamines
268. The extraneuronal uptake and metabolism of catecholamines
269. The uptake and metabolism of 3H-catecholamines in rat cerebral cortex slices
270. The interaction of transport mechanisms and intracellular enzymes in metabolizing systems
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272. The influence of intraneuronal monoamine oxidase on neuronal net uptake of noradrenaline and on sensitivity to noradrenaline
273. Radioiodinated metaiodobenzylguanidine *I-MIBG scintigraphy in neuroblastoma: A review of 160 studies
274. Expression of a pulmonary endothelial norepinephrine transporter
275. Demonstration of regional sympathetic denervation of the heart in diabetes. Comparison between patients with NIDDM and IDDM
276. Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs
277. Cloning of the cocaine-sensitive bovine dopamine transporter
278. 3-[211At]astato-4-fluorobenzylguanidine: A potential therapeutic agent with prolonged retention by neuroblastoma cells
279. Atrial natriuretic factor effects on norepinephrine uptake in discrete telencephalic and diencephalic nuclei of the rat
280. Protein kinase C-mediated phosphorylation and functional regulation of dopamine transportersin striatal synaptosomes
281. Age differences in plasma norepinephrine kinetics in humans
282. The effects of phosphorylation on the functional regulation of an expressed recombinant human dopamine transporter
283. Mice lacking the dopamine transporter display altered regulation of distal colonic motility
284. 3H-norepinephrine in animals
285. The human norepinephrine transporter: Characterization of alternatively spliced isoforms
286. Analysis of the gene structure of the human SLC22A3 and murine Slc22a3 extraneuronal monoamine transporter
287. 18F]fluorometaraminol
288. Derivation of urinary dopamine from plasma dihydroxyphenylalanine in humans
289. Identity of the organic cation transporter OCT3 as the extraneuronal monoamine transporter uptake2 and evidence for the expression of the transporter in the brain
290. Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney
291. Mice lacking the norepinephrine transporter are supersensitive to psychostimulants
292. Estimation of striatal dopamine spillover and metabolism in vivo
293. Effects of locally administered desipramine on myocardial interstitial norepinephrine levels
294. A new, concise dialysis approach to assessment of cardiac sympathetic nerve terminal abnormalities
295. MAP kinase-independent signaling in angiotensin II regulation of neuromodulation in SHR neurons
296. Role of phosphatidylinositol 3-kinase in angiotensin II regulation of norepinephrine neuromodulation in brain neurons of the spontaneously hypertensive rat
297. Involvement of sialic acid in high-affinity uptake of dopamine by synaptosomes from rat brain
298. Regulation of the functional activity of the human dopamine transporter by protein kinase C
299. Cloning and functional expression of a human liver organic cation transporter
300. Characterization of cocaine-sensitive dopamine uptake in PC12 cells
301. Activation of protein kinase C inhibits uptake, currents and binding associated with the human dopamine transporter expressed in Xenopus oocytes
302. Microdialysis as a tool for in vivo study of dopamine transporter function in rat brains