Counterregulation in peripheral tissues: Effect of systemic hypoglycemia on levels of substrates and catecholamines in human skeletal muscle and adipose tissue

Diabetes

Volumn 46, Issue 1, 1997, Pages 70-76

  Maggs, David G ^a,b   Jacob, Ralph ^a   Rife, Francis ^a   Caprio, Sonia ^a   Tamborlane, William V ^a   Sherwin, Robert S ^a  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TISSUE; ARTICLE; DIABETES MELLITUS; FEMALE; HUMAN; HUMAN TISSUE; HYPERINSULINEMIA; HYPOGLYCEMIA; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; TISSUE LEVEL;

EID: 0031023327     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.46.1.70     Document Type: Article

References (32)

1. Cryer P, Gerich J: Glucose counterregulation, hypoglycaemia, and intensive insulin therapy in diabetes mellitus. N Engl J Med 313:232-241, 1985
2. McGuire E, Helderman J, Tobin J, Andres R, Bergman R: Effects of arterial versus venous sampling on glucose kinetics in man. J Appl Physiol 41:65-73, 1976
3. During M, Spencer D: Adenosine: a potential mediator of seizure arrest and postictal refractoriness. Ann Neurol 32:618-624, 1992
4. Jacobson I, Sandberg M, Hamberger A: Mass transfer in brain dialysis devices: a new method for the estimation of extracellular amino acids concentration. J Neurosci Meth 15:263-268, 1985
5. De Fronzo R, Jordan J, Andres T, Andres R: Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237:E214-E223, 1979
6. Simonson D, Tamborlane W, Sherwin R, DeFronzo R: Improved insulin sensitivity in type I diabetes after chronic insulin pump treatment Diabetes 34 (Suppl. 3):80-86, 1985
7. Lonnroth P, Jansson P-A, Smith U: A microdialysis method allowing characterisation of intercellular water space in humans. Am J Phys 253:E228-E231, 1987
8. Muller M, Schmid R, Nieszpaur-Los M, Fassolt A, Lonnroth P, Fasching P, Eichler H: Key metabolite kinetics in human skeletal muscle during ischaemia and reperfusion: measurement by microdialysis. Eur J Clin Invest 25:601-607, 1995
9. Maggs D, Jacob R, Rife F, Lange R, Leone P, During M, Tamborlane W, Sherwin R: Interstitial fluid concentrations of glycerol, glucose, and amino acids in human quadricep muscle and adipose tissue: evidence of significant lipolysis in skeletal muscle. J Clin Invest 96:370-377, 1995
10. de Boer J, Postema F, Plijter-Groendijk H, Korf J: Continuous monitoring of extracellular lactate concentration by microdialysis lactography for the study of rat muscle metabolism in vivo. Pflugers Arch 419:1-6, 1991
11. Jansson P, Smith U, Lonnroth P: Evidence for lactate production by human adipose tisue in vivo. Diabetologia 33:253-256, 1990
12. Coppack S, Frayn K, Humphreys S, Whyte P, Hockaday T: Arteriovenous differences across human adipose and forearm tissues after overnight fast. Metabolism 39:384-390, 1990
13. Cohen N, Rossetti L, Shlimovich P, Halberstam M, Hu M, Shamoon H: Counterregulation of hypoglycemia: skeletal muscle glycogen metabolism during three hours of physiological hyperinsulinemia in humans. Diabetes 44:423-430, 1995
14. Davis S, Shavers C, Collins L, Cherrington A, Price L, Hedstrom C: Effects of physiological hyperinsulinemia on counterregulatory response to prolonged hypoglycemia in normal humans. Am J Physiol 267:E402-E410, 1994
15. Sacca L, Sherwin R, Hendler R, Felig P: Influence of continuous physiologic hyperinsulinemia on glucose kinetics and counterregulatory hormones in normal and diabetic humans. J Clin Invest 63:849-857, 1979
16. Suda S, Shinohara M, Miyaoka M, Lucignani G, Kennedy C, Sokoloff L: The lumped constant of deoxyglucose method in hypoglycemia: effects of moderate hypoglycemia on local cerebral glucose utilization in the rat J Cer Blood Flow Met 10:765-773, 1990
17. Lucignani G, Namba H, Nehlig A, Porrino L, Kennedy C, Sokoloff L: Effects of insulin on local cerebral glucose utilization in the rat. J Cer Blood flow Met 7:309-314, 1987
18. Boyle P, Nagy R, O'Connor A, Kempers S, Yeo R, Quails C: Adaptation in brain glucose utilization following recurrent hypoglycemia. Proc Natl Acad Sci USA 91:9352-9356, 1994
19. Hickner R, Rosdahl H, Borg I, Ungerstedt U, Jorfeldt L, Henriksson J: Ethanol may be used with the microdialysis technique to monitor blood flow changes in skeletal muscle: dialysate glucose concentration is blood-flow-dependent. Acta Physiol Scand 143:355-356, 1991
20. Hickner R, Rosdahl H, Borg I, Ungerstedt U, Jorfeldt L, Henriksson J: The ethanol technique of monitoring local blood flow changes in rat skeletal muscle: implications for microdialysis. Acta Physiol Scand 146:87-97, 1992
21. Rosdahl H, Ungerstedt U, Jorfeldt L, Henriksson J: Interstitial glucose and lactate balance in human skeletal muscle and adipose tissue studied by microdialysis. J Physiol 471:637-657, 1993
22. Hickner R, Ungerstedt U, Henriksson J: Regulation of skeletal blood flow during acute insulin-induced hypoglycemia in the rat Diabetes 43:1340-1344, 1994
23. Fuchi T, Rosdahl H, Hickner R, Ungerstedt U, Henriksson J: Microdialysis of rat skeletal muscle and adipose tissue: dynamics of the interstitial glucose pool. Acta Physiol Scand 151:249-260, 1994
24. Caprio S, Sacca L, Tamborlane W, Sherwin R: Relationship between changes in glucose production and gluconeogenesis during mild hypoglycemia in humans. Metab Clin Exp 8:707-710, 1988
25. Fanelli C, De Feo P, Porcellati F, Perriello G, Torlone E, Santeusanio F, Brunetti P, Bolli G: Adrenergic mechanisms contribute to the late phase of hypoglycemic glucose counterregulation in humans by stimulating lipolysis. J Clin Invest 89:2005-2013, 1992
26. Fanelli C, Calderone S, Epifano L, De Vincenzo A, Modarelli F, Pampanelli S, Perriello G, De Feo P, Brunetti P, Gerich J, Bolli G: Demonstration of a critical role for free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilization in humans. J Clin Invest 92:1617-1622, 1993
27. Obata T, Hosokawa H, Yamanaka Y: In vivo monitoring of norepinephrine and -OH generation in myocardial ischemic injury by dialysis technique Am J Physiol 266:H903-H908, 1994
28. Gronlund B, Astrup A, Bie P, Christensen N: Noradrenaline release in skeletal muscle and in adipose tissue studied by microdialysis. Cli Sci 80:595-598, 1991
29. Mertes P, Carteaux J, Jaboin Y, Pinelli G, El Abassi K, Dopff C, Atkinson J, Villemot J, Burlet C, Boulange M: Estimation of myocardial interstitial norepinephrine release after brain death using cardiac microdialysis. Transplantation 57:371-377, 1994
30. Anderson E, Hoffman R, Balon T, Sinkey C, Mark A: Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 87:2246-2252, 1991
31. Rowe J, Young J, Minaker K, Stevens A, Pallotta J, Landsberg L: Effect of insulin and glucose infusions on sympathetic nervous activity in normal man. Diabetes 30:219-225, 1981
32. Hoffman R, Sinkey C, Anderson E: Hypoglycemia increases muscle sympathetic nerve activity in IDDM and control subjects. Diabetes Care 17:673-680, 1994