Different relationships of spillover to release of norepinephrine in human heart, kidneys, and forearm

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 275, Issue 1 44-1, 1998, Pages

  Kopin, Irwin J ^a   Rundqvist, Bengt ^b   Friberg, Peter ^b   Lenders, Jacques ^c   Goldstein, David S ^a   Eisenhofer, Graeme ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Catecholamines; Kinetics; Metanephrine; Normetanephrine; Sympathetic nervous system

Indexed keywords

NORADRENALIN;

ADRENERGIC SYSTEM; ARTICLE; CATECHOLAMINE BLOOD LEVEL; FOREARM; HEART; HUMAN; HUMAN TISSUE; INTERSTITIAL FLUID; KIDNEY; NERVE STIMULATION; NEUROTRANSMISSION; NORADRENALIN BLOOD LEVEL; NORADRENALIN RELEASE; PRIORITY JOURNAL; SYMPATHETIC NERVE; SYMPATHETIC TONE;

EID: 0031867929     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.275.1.r165     Document Type: Article

References (38)

1. Chang, P. C., E. Kriek, J. A. van der Krogt, and P. van Brummelen. Does regional norepinephrine spillover represent local sympathetic activity? Hypertension 18: 56-66, 1991.
2. Cousineau, D., C. P. Rose, and C. A. Goresky. Labeled catecholamine uptake in the dog heart. Interactions between capillary wall and sympathetic nerve uptake. Circ. Res. 47: 329-338, 1980.
3. Cox, H. S., D. M. Kaye, J. M. Thompson, A. G. Turner, G. L. Jennings, C. Itsiopoulos, and M. D. Esler. Regional sympathetic nervous activation after a large meal in humans. Clin. Sci. (Colch.) 89: 145-154, 1995.
4. Eisenhofer, G. In vivo kinetics of catecholamines. J. Auton. Pharmacol. 14: 7-8, 1994.
5. Eisenhofer, G., A. Aneman, D. Hooper, B. Rundqvist, and P. Friberg. Mesenteric organ production, hepatic metabolism, and renal elimination of norepinephrine and its metabolites in humans. J. Neurochem. 66: 1565-1573, 1996.
6. Eisenhofer, G., P. Friberg, B. Rundqvist, A. A. Quyyumi, G. Lambert, D. M. Kaye, I. J. Kopin, D. S. Goldstein, and M. D. Esler. Cardiac sympathetic nerve function in congestive heart failure. Circulation 93: 1667-1676, 1996.
7. Eisenhofer, G., B. Rundqvist, A. Aneman, P. Friberg, N. Dakak, I. J. Kopin, M. C. Jacobs, and J. W. Lenders. Regional release and removal of catecholamines and extraneuronal metabolism to metanephrines. J. Clin. Endocrinol. Metab. 80: 3009-3017, 1995.
8. Esler, M. Clinical application of noradrenaline spillover methodology: delineation of regional human sympathetic nervous responses. Pharmacol. Toxicol. 73: 243-253, 1993.
9. Esler, M., G. J. Hasking, I. R. Willett, P. W. Leonard, and G. L. Jennings. Noradrenaline release and sympathetic nervous system activity. J. Hypertens. 3: 117-129, 1985.
10. Esler, M., G. Jennings, P. Korner, P. Blombery, F. Burke, I. Willett, and P. Leonard. Total, and organ-specific, noradrenaline plasma kinetics in essential hypertension. Clin. Exp. Hypertens. 6: 507-521, 1984.
11. Esler, M., G. Jennings, G. Lambert, I. Meredith, M. Horne, and G. Eisenhofer. Overflow of catecholamine neurotransmitters to the circulation: source, fate, and functions. Physiol. Rev. 70: 963-985, 1990.
12. Esler, M., G. Jennings, P. Leonard, N. Sacharias, F. Burke, J. Johns, and P. Blombery. Contribution of individual organs to total noradrenaline release in humans. Acta Physiol. Scand. Suppl. 527: 11-16, 1984.
13. Esler, M., G. Lambert, and G. Jennings. Increased regional sympathetic nevous activity in human hypertension: causes and consequences. J. Hypertension 8, Suppl. 7: S53-S57, 1990.
14. Esler, M. D., J. M. Thompson, D. M. Kaye, A. G. Turner, G. L. Jennings, H. S. Cox, G. W. Lambert, and D. R. Seals. Effects of aging on the responsiveness of the human cardiac sympathetic nerves to stressors. Circulation 91: 351-358, 1995.
15. Folkow, B., G. F. DiBona, P. Hjemdahl, P. H. Toren, and B. G. Wallin. Measurements of plasma norepinephrine concentrations in human primary hypertension. A word of caution on their applicability for assessing neurogenic contributions. Hypertension 5: 399-403, 1983.
16. Goldstein, D. S. Plasma catecholamines in clinical studies of cardiovascular diseases. Acta Physiol. Scand. Suppl. 527: 39-41, 1984.
17. Goldstein, D. S. Plasma norepinephrine in essential hypertension: the elusive measurement. In: Trends in Autonomic Pharmacology, edited by S. Kalsner. Philadelphia, PA: Taylor and Francis, 1985, p. 331-349.
18. Goldstein, D. S., J. E. Brush, Jr., G. Eisenhofer, R. Stull, and M. Esler. In vivo measurement of neuronal uptake of norepinephrine in the human heart. Circulation 78: 41-48, 1988.
19. Goldstein, D. S., G. Eisenhofer, R. Stull, C. J. Folio, H. R. Keiser, and I. J. Kopin. Plasma dihydroxyphenylglycol and the intraneuronal disposition of norepinephrine in humans. J. Clin. Invest. 81: 213-220, 1988.
20. Goldstein, D. S., R. Zimlichman, R. Stull, J. Folio, P. D. Levinson, H. R. Keiser, and I. J. Kopin. Measurement of regional neuronal removal of norepinephrine in man. J. Clin. Invest. 76: 15-21, 1985.
21. Grossman, E., P. C. Chang, A. Hoffman, M. Tamrat, I. J. Kopin, and D. S. Goldstein. Tracer norepinephrine kinetics: dependence on regional blood flow and the site of infusion. Am. J. Physiol. 260 (Regulatory Integrative Comp. Physiol. 29): R946-R952, 1991.
22. Holmes, C., G. Eisenhofer, and D. S. Goldstein. Improved assay for plasma dihydroxyphenylacetic acid and other catechols using high-performance liquid chromatography with electrochemical detection. J. Chromatogr. B Biomed. Appl. 653: 131-138, 1994.
23. Johnson, J. A., and T. A. Wilson. A model for capillary exchange. Am. J. Physiol. 210: 1299-1303, 1966.
24. Karlsson, A. K., M. Elam, P. Friberg, F. Biering-Sorensen, L. Sullivan, and P. Lonnroth. Regulation of lipolysis by the sympathetic nervous system: a microdialysis study in normal and spinal cord-injured subjects. Metabolism 46: 388-394, 1997.
25. Kim, Y. D., C. R. Lake, D. E. Lees, W. H. Schuette, J. M. Bull, V. K. Weise, and I. J. Kopin. Hemodynamic and plasma catecholamine responses to hyperthermic cancer therapy in humans. Am. J. Physiol. 237 (Heart Circ. Physiol. 6): H570-H574, 1979.
26. Kopin, I. J. Plasma levels of catecholamines and dopamine-betahydroxylase. In: Catecholamines II, edited by U. Trendelenburg and N. Weiner. Berlin: Springer-Verlag, 1988, p. 211-275.
27. Lenders, J. W. M., G. Eisenhofer, I. Armando, H. R. Keiser, D. S. Goldstein, and I. J. Kopin. Determination of plasma metanephrines by liquid chromatography with electrochemical detection. Clin. Chem. 39: 97-103, 1993.
28. Levitt, D. G. Theoretical model of capillary exchange incorporating interactions between capillaries. Am. J. Physiol. 220: 250-255, 1971.
29. Lonnroth, P., P. A. Jansson, and U. Smith. A microdialysis method allowing characterization of intercellular water space in humans. Am. J. Physiol. 253 (Endocrinol. Metab. 16): E228-E231, 1987.
30. Meredith, I. T., M. D. Esler, H. S. Cox, G. W. Lambert, G. L. Jennings, and G. Eisenhofer. Biochemical evidence of sympathetic denervation of the heart in pure autonomic failure. Clin. Auton. Res. 1: 187-194, 1991.
31. Meredith, I. T., P. Friberg, G. L. Jennings, E. M. Dewar, V. A. Fazio, G. W. Lambert, and M. D. Esler. Exercise training lowers resting renal but not cardiac sympathetic activity in humans. Hypertension 18: 575-582, 1991.
32. Rose, C. P., J. H. Burgess, and D. Cousineau. Tracer norepinephrine kinetics in coronary circulation of patients with heart failure secondary to chronic pressure and volume overload. J. Clin. Invest. 76: 1740-1747, 1985.
33. Rudolph, A. M., H. S. Iwamoto, and D. F. Teitel. Circulatory changes at birth. J. Perinat. Med. 16, Suppl. 1: 9-21, 1988.
34. Seals, D. R., J. A. Taylor, A. V. Ng, and M. D. Esler. Exercise and aging: autonomic control of the circulation. Med. Sci. Sports Exerc. 26: 568-576, 1994.
35. 14C-glucose in the dog. Am. J. Physiol. 196: 221-230, 1959.
36. Stetten, D., I. D. Watt, D. J. Ingle, E. H. Morely. Rates of glucose production and oxidation in normal and diabetic rats. J. Biol. Chem. 192: 817-830, 1951.
37. Wearn, J. T. The extent of the capillary bed of the heart. J. Exp. Med. 47: 273-292, 1928.
38. Ziegler, W. H., and C. A. Goresky. Transcapillary exchange in the working left ventricle of the dog. Circ. Res. 29: 181-207, 1971.