Detection of dopaminergic neurotransmitter activity using pharmacologic MRI: Correlation with PET, microdialysis, and behavioral data

Magnetic Resonance in Medicine

Volumn 38, Issue 3, 1997, Pages 389-398

  Chen, Yin Ching I ^a   Galpern, Wendy R ^d   Brownell, Anna Liisa ^b   Matthews, Russell T ^c   Bogdanov, Mikhail ^c   Isacson, Ole ^d   Keltner, John R ^a   Beal, M Flint ^c   Rosen, Bruce R ^a   Jenkins, Bruce G ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Department of Radiology

^c Department of Neurology

^d MCLEAN HOSPITAL   (United States)

Author keywords

Amphetamine; CFT; Dopamine; fMRI

Indexed keywords

AMINES; ANIMALS; BLOOD PRESSURE; DIALYSIS; POSITRON EMISSION TOMOGRAPHY;

6-HYDROXYDOPAMINE (6-OHDA); AMPHETAMINE; CONTROL MEASUREMENTS; DOPAMINE; DOPAMINE TRANSPORTERS; FMRI; METABOLIC ACTIVATION; POSITRON EMISSION TOMOGRAPHY (PET);

NEUROPHYSIOLOGY;

AMPHETAMINE; DOPAMINE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; BRAIN SCINTISCANNING; DOPAMINERGIC SYSTEM; DRUG RECEPTOR BINDING; IMAGE ANALYSIS; ISOTOPE LABELING; NEUROTRANSMISSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; RAT; RECEPTOR DENSITY;

EID: 9844250214     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.1910380306     Document Type: Article

References (31)

1. J. W. Belliveau, D. N. Kennedy, R. C. McKinstry, B. R. Buchbinder, R. M. Weisskoff, M. S. Cohen, J. M. Vovea, T. J. Brady, B. R. Rosen, Functional mapping of the human visual cortex by magnetic resonance imaging. Science 254, 716-719 (1991).
2. K. K. Kwong, J. W. Belliveau, D. A. Chester, I. E. Coldberg, R. M. Weisskoff, B. P., Poncelet, D. N. Kennedy, B. E. Hoppel, M. S. Cohen, R. Turner, H. M. Cheng, T. J. Brady, B. R. Rosen, Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc. Natl. Acad. Sci. 89, 5675-5679 (1992).
3. S. Ogawa, D. W. Tank, R. Menon, J. M. Ellermann, S-G. Kim, H. Merkle, K. Ugurbil, Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc. Natl. Acad. Sci 89, 5951-5955 (1992).
4. C. Carlsson, M. Hagerdal, B. K. Siesjo, Influence of amphetamine sulfate on cerebral blood flow and metabolism. Acta Physiol. Scand. 94, 128-129 (1975).
5. M. McCulloch, A. M. Harper, Cerebral circulatory and metabolism changes following amphetamine administration. Brain Res. 121, 196-199 (1977).
6. L. R. Wechsler, H. E. Savaki, L. Sokoloff, Effects of d- and l-amphetamine on local cerebral glucose utilization in the conscious rat. J. Neurochem. 32, 15-22 (1979).
7. K. E. Russo, W. Hall, O. Z. Chi, A. K. Sinha, H. R. Weiss, Effect of amphetamine on cerebral blood flow and capillary perfusion. Brain Res. 542, 43-48 (1991).
8. C. A. Cuenod, M. C. J. Chang, T. Arai, L. Pannier, S. Posse, D. Despres, J. A. Frank, S. Rappoport, D. LeBihan, Local brain response to cholinergic receptor stimulation detected by MRI, in "Proc., SMRM, 12th Annual Meeting, 1993," p. 1387.
9. A. D. Silva, W. Zhang, D. S. Williams, A. P. Koretsky, Multislice MRI of rat brain during amphetamine stimulation using arterial spin labelling. Magn. Reson. Med. 33, 209-214 (1995).
10. Y. I. Chen, B. G. Jenkins, R. T. Matthews, K. K. Kwong, J. R. Keltner, S. J. Fink, B. R. Rosen, Evaluation of Neuronal loss and striatal activation in a rat model of Parkinson's disease using MRS and fMRI, in "Proc., SMR, 3rd Annual Meeting, Nice, France, 1995," p. 1357.
11. Q. Chen, A. H. Andersen, Z. Zhang, A. Ovadia, D.M. Cash, M. J. Avison, Nigrostrialal R2* changes in Hemiparkinsonian Rhesus in response to L-DOPA, in "Proc., SMR, 3rd Annual Meeting, Nice, France, 1995," p. 1358.
12. C. J. Aine, A conceptual overview and critique of functional neuroimaging techniques in humans: I. MRI/FMRI and PET. Crit Rev. Neurobiol. 9(2-3), 229-309 (1995).
13. A. P. Wolf, J. S. Fowler, Positron emission tomography: biomedical research and clinical application. Neuroimaging Clin. N. Am. 5(1), 87-101 (1995).
14. G. W. Arbuthnott, I. S. Fairbrother, S. P. Butcher, Dopamine release and metabolism in the rat striatum: an analysis by in vivo brain microdialysis. Pharmacol. Ther. 48(3), 281-293 (1990).
15. D. A. Perese, J. Ulman, J. Viola, S. E. Ewing, K. S. Bankiewicz, A 6-hydroxydopamine-induced selective parkinsonian rat model. Brain Res. 494, 285-293 (1989).
16. M. J. Zigmond, E. D. Abercrombie, T. W. Berger, A. A. Grace, E. M. Stricker, Compensations after lesions of central dopaminergic neurons: some clinical and basic implications, (1990).
17. B. Giros, M. Jaber, S. R. Jones, R. M. Wightman, M. G. Caron, Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379, 606-612 (1996).
18. 3H] Cocaine binding sites in caudate-putamen. J. Pharmacol. Exp. Ther. 251(1), 131-141 (1989).
19. 3H]2β-carbomethoxy-3β-(4-fluorophenyl)tropane. Mol. Pharmacol. 36, 518-524 (1989).
20. G. L. Brownell, C. A. Burnham, C. W. Sterns, D. A. Chesler, A-L. Brownell, M. R. Palmer, Developments in high-resolution positron emission tomography at MGH, Internatl. J. Imag. Sys. Technol. 1, 207-217 (1989).
21. G. Paxinos, C. Watson, "The rat brain in stereotaxic coordinates," Academic Press, San Diego, 1986.
22. A. D. Silva, W. Zhang, D. S. Williams, A. P. Koretsky, Multislice MRI of rat brain during amphetamine stimulation using arterial spin labeling. Magn. Reson. Med. 33, 209-214 (1995).
23. A. Villringer, B. R. Rosen, J. W. Belliveau, J. L. Acerman, R. B. Lauffer, R. B. Buxton, Y. S. Chao, V. J. Wedeen, T. J. Brady, Dynamic imaging with lanthanidechelates in normal brain: contrast due to magnetic susceptibility effects. Magn. Reson. Med. 6(2), 164-174 (1988).
24. L. M. Hamberg, R. Macfarlane, E. Tasdemiroglu, P. Boccalini, B.G. Hunter, J. W. Belliveau, M. A. Moskowitz, B. R. Rosen, Measurement of cerebrovascular changes in cats after transient ischemia using dynamic magnetic resonance imaging. Stroke 24(3), 444-450 (1993).
25. J. A. Detre, J. S. Leigh, D. S. Williams, A. P. Koretsky, Perfusion Imaging. Magn. Reson. Med. 23, 37-45 (1992).
26. D. Kuczenski, D. Segal, Concomitant characterization of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis. J. Neurosci. 9, 2051-2065 (1989).
27. T. E. Robinson, E. Castaneda, I. Q. Whishaw, Compensatory changes in striatal dopamine neurons following recovery from injury induced by 6-OHDA or methamphetamine: a review of evidence from microdialysis studies. Can. J. Psychol. 44, 253-275 (1990).
28. L. S. Carman, F. H. Gage, C. W. Shults, Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior. Brain Res. 553, 275-283 (1991).
29. U. Wullner, P. Pakzaban, A. L. Brownell, et al., Dopamine terminal loss and onset of motor symptoms in MPTP-treated monkeys: a positron emission tomography study with 1IC-CFT. Exp. Neurol. 126(2), 305-309 (1994).
30. S. N. Haber, H. Ryoo, C. Cox, W. Lu, Subsets of midbrain dopaminergic neurons in monkeys are distinguished by different levels of mRNA for the dopamine transporter: comparison with the mRNA for the D2 receptor, tyrosine hydroxylase and calbindin immunoreactivity. J. Comp. Neurol. 362(3), 400-410 (1995).
31. V. Blanchard, R. Raisman-Vozari, S. Vyas, P. P. Michel, F. Javoy-Agid, G. Uhl, Y. Agid, Differential expression of tyrosine hydroxylase and membrane dopamine transporter genes in subpopulations of dopaminergic neurons of the rat mesencephalon, Brain Res. 22(1-4), 29-38 (1994).