1,1'-Diisopropyl-2,4'-cyanine (disprocynium24), a potent uptake2 blocker, inhibits the renal excretion of catecholamines

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 356, Issue 1, 1997, Pages 115-125

  Graefe, Karl Heinz ^a   Friedgen, Bernd ^a   Wölfel, Reinhard ^a   Bossle, Franz ^a   Russ, Hermann ^b   Schömig, Edgar ^c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Adrenaline; Disprocynium24; Dopamine; Inulin clearance; Noradrenaline; Organic cation transport; Renal excretion; Uptake2

Indexed keywords

ADRENALIN; DOPAMINE; ION TRANSPORT AFFECTING AGENT; NORADRENALIN;

ANIMAL EXPERIMENT; ARTICLE; CATECHOLAMINE EXCRETION; CATION TRANSPORT; CONTROLLED STUDY; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; RABBIT; URINARY EXCRETION;

ANIMALS; CATECHOL O-METHYLTRANSFERASE; CATECHOLAMINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE; EPINEPHRINE; GLOMERULAR FILTRATION RATE; MALE; MONOAMINE OXIDASE INHIBITORS; NEUROTRANSMITTER AGENTS; NOREPINEPHRINE; QUINOLINES; RABBITS;

EID: 0030977635     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005018     Document Type: Article

References (40)

1. Baines AD, Chan W (1980) Production of urine free dopamine from DOPA; a micropuncture study. Life Sci 26: 253-259
2. Baines AD, Drangova R (1986) Neural not tubular dopamine increases glomerular filtration rate in perfused rat kidneys. Am J Physiol 250 (Renal Fluid Electrolyte Physiol 19): F674-F679
3. Baines AD, Craan A, Chan W, Morgunov N (1979) Tubular secretion and metabolism of dopamine, norepinephrine, methoxytyramine and normetanephrine by the rat kidney. J Pharmacol Exp Ther 208: 144-147
4. Baines AD, Drangova R, Hatcher C (1985) Dopamine production by isolated glomeruli and tubules from rat kidneys. Can J Physiol Pharmacol 63: 155-158
5. Ball SG, Lee MR (1977) The effect of carbidopa administration on urinary sodium excretion in man. Is dopamine an intrarenal natriuretic hormone? Br J Clin Pharmacol 4: 115-119
6. Ball SG, Gunn IG, Douglas IHS (1982) Renal handling of dopa, dopamine, norepinephrine, and epinephrine in the dog. Am J Physiol 242 (Renal Fluid Electrolyte Physiol. 11): F56-F62
7. Breidert T, Gründemann D, Spitzenberger F, Schömig E (1997) The organic cation transporter OCT1 accepts biogenic amines as substrates. Naunyn-Schmiedeberg's Arch Pharmacol 355 [Suppl]: R25
8. Brown MJ, Allison DJ (1981) Renal conversion of plasma DOPA to urine dopamine. Br J Clin Pharmacol 12: 251-253
9. Busch AE, Quester S, Ulzheimer JC, Gorboulev V, Akhoundova A, Waldegger S, Lang F, Koepsell H (1996) Monoamine neurotransmitter transport mediated by the polyspecific cation transporter rOCT1. FEBS Lett 395: 153-156
10. Esler M (1989) Renal catecholamine metabolism. Miner Electrolyte Metab 15: 16-23
11. Friedgen B, Halbrügge T, Graefe K-H (1993) The part played by catechol-O-methyltransferase in the plasma kinetics of 3,4-dihydroxyphenylglycol and 3,4-dihydroxyphenylalanine in the anaesthetized rabbit. Naunyn-Schmiedebera's Arch Pharmacol 347: 155-161
12. 1 and catechol-O-methyltransferase in removal of circulating catecholamines in the rabbit. Am J Physiol 267 (Endocrinol. Metab. 30): E814-E821
13. Friedgen B, Wölfel R, Graefe K-H (1996a) The contribution by monoamine oxidase and catechol-O-methyltransferase to the total-body and pulmonary plasma clearance of catecholamines. Naunyn-Schmiedeberg's Arch Pharmacol 353: 193-199
14. Friedgen B, Wölfel R, Russ H, Schömig E, Graefe K-H (1996b) The role of extraneuronal amine transport systems for the removal of extracellular catecholamines in the rabbit. Naunyn-Schmiedeberg's Arch Pharmacol 354: 275-286
15. Goldstein DS, Grossman E, Armando I, Wolfovitz E, Folio CJ, Holmes C, Keiser H.R. (1993) Correlates of urinary excretion of catechols in humans. Biogenic Amines 10: 3-17
16. Gründemann D, Gorboulev V, Gambaryan S, Veyhl M, Koepsell H (1994) Drug excretion mediated by a new prototype of polyspecific transporter. Nature 372: 549-552
17. 1 cells. J Biol Chem 272: 10408-10413
18. Ibarra FR, Aguirre J, Nowicki S, Barontini M, Arrizurieta EE, Armando I (1996) Demethylation of 3-O-methyldopa in the kidney: a possible source for dopamine in urine. Am J Physiol 270 (Renal Fluid Electrolyte Physiol 39): F862-F868
19. Kopp U, Bradley T, Hjemdahl P (1983) Renal venous outflow and urinary excretion of norepinephrine, epinephrine, and dopamine during graded renal nerve stimulation. Am J Physiol 244 (Endocrinol Metab. 7): E52-E60
20. Lappe RW, Henry DP, Willis LR (1980) Mechanism of renal tubular secretion of norepinephrine in the rabbit. J Pharmacol Exp Ther. 215: 443-449
21. Lappe RW, Henry DP, Willis LR (1982) Contribution of renal sympathetic nerves to the urinary excretion of norepinephrine. Can J Physiol Pharmacol 60: 1067-1072
22. Lee MR (1982) Dopamine and the kidney. Clin Sci 62, 439-448
23. Mack F, Bönisch H (1979) Dissociation constants and lipophilicity of catecholamines and related compounds. Naunyn-Schmiedeberg's Arch Pharmacol 310: 1-9
24. Martel F, Vetter T, Russ H, Gründemann D, Azevedo I, Koepsell H, Schömig E (1996) Transport of small organic cations in the rat liver; the role of the organic cation transporter OCT1. Naunyn-Schmiedeberg's Arch Pharmacol 354: 320-326
25. Morgunov N, Baines AD (1981) Renal nerves and catecholamine excretion. Am J Physiol 240 (Renal Fluid Electrolyte Physiol 9): F75-F81
26. Pritchard JB, Miller DS (1993) Mechanisms mediating renal secretion of organic anions and cations. Physiol Rev 73: 765-796
27. Quebbemann A, Rennick B (1970) Inhibition of renal tubular transport of catecholamines by cocaine: an organic base mechanism. J Pharmacol Exp Ther 175: 248-258
28. Rennick BR (1981) Renal tubule transport of organic cations. Am J Physiol 240 (Renal Fluid Electrolyte Physiol 9): F83-F89
29. Rennick BR, Pryor MZ (1965) Effects of autonomic drugs on renal tubular transport of catecholamines in the chicken. J Pharmacol Exp Ther 148: 262-269
30. Rennick BR, Kandel A, Peters L (1956) Inhibition of the renal tubular excretion of tetraethylammonium and N′-methylnicotinamide by basic cyanine dyes. J Pharmacol Exp Ther 118: 204-219
31. Russ H, Engel W, Schömig E (1993a) Isocyanines and pseudoisocyanines as a novel class of potent noradrenaline transport inhibitors: synthesis, detection, and biological activity. J Med Chem 36: 4208-4213
32. Russ H, Sonna J, Keppler K, Baunach S, Schömig E (1993b) Cya-nine-related compounds: a novel class of potent inhibitors of extraneuronal noradrenaline transport. Naunyn-Schmiedeberg's Arch Pharmacol 348: 458-465
33. 2) in a human cell line (Caki-1 cells). Naunyn-Schmiedeberg's Arch Pharmacol 341: 404-410
34. Schömig E, Babin-Ebell J, Russ H (1993) 1,1′-Diethyl-2,2′-cyanine (decynium22) potently inhibits the renal transport of organic cations. Naunyn-Schmiedeberg's Arch Pharmacol 347: 379-383
35. Silva P, Landsberg L, Besarab A (1979) Excretion and metabolism of catecholamines by the isolated perfused rat kidney. J Clin Invest 64: 850-857
36. Stephenson RK, Sole MJ, Baines AD (1982) Neural and extraneural catecholamine production by rat kidneys. Am J Physiol 242 (Renal Fluid Electrolyte Physiol 11): F261-F266
37. Szabo B, Schramm A, Starke K (1992) Effect of yohimbine on renal sympathetic nerve activity and renal norepinephrine spillover in anesthetized rabbits. J Pharmacol Exp Ther 260: 780-788
38. Trendelenburg U (1980) A kinetic analysis of extraneuronal uptake and metabolism of catecholamines. Rev Physiol Biochem Pharmacol 87: 33-115
39. Trendelenburg U (1988) The extraneuronal uptake and metabolism of catecholamines. In: Handbook of Experimental Pharmacol (Catecholamines I), vol. 90/1, edited by U. Trendelenburg and N. Weiner. Springer, Berlin Heidelberg New York pp 279-319
40. Linger T, Buu NT, Kuchel O (1978) Renal handling of free and conjugated catecholamines following surgical stress in the dog. Am. J. Physiol. 235 (Renal Fluid Electrolyte Physiol. 4): F542-F547