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Volumn 2, Issue 10, 2001, Pages 1531-1543

Prospects for the treatment of Parkinson's disease using neurotrophic factors

Author keywords

Animal models; Glial cell line derived neurotrophic factor; Growth factor; Transforming growth factor

Indexed keywords

4 AMINOBUTYRIC ACID; ACIDIC FIBROBLAST GROWTH FACTOR; ALPHA SYNUCLEIN; ARTEMIN; BASIC FIBROBLAST GROWTH FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; DOPAMINE; EPIDERMAL GROWTH FACTOR; GANGLIOSIDE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GROWTH DIFFERENTIATION FACTOR 15; GROWTH DIFFERENTIATION FACTOR 5; INTERLEUKIN 1; INTERLEUKIN 6; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; NEUROTROPHIN; NEURTURIN; PERSEPHIN; PLATELET DERIVED GROWTH FACTOR; SEROTONIN; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VIRUS VECTOR;

EID: 0034758936     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.2.10.1531     Document Type: Review
Times cited : (21)

References (148)
  • 12
    • 0030031116 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor exerts neurotrophic effects on dopaminergic neurons in vitro and promotes their survival and regrowth after damage by 1-methyl-4-phenylpyridinium
    • (1996) J. Neurochem. , vol.66 , pp. 74-82
    • Hou, J.G.1    Lin, L.F.2    Mytilineou, C.3
  • 24
    • 0014954436 scopus 로고
    • Quantitative recording of rotational behavior in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system
    • (1970) Brain Res. , vol.24 , pp. 485-493
    • Ungerstedt, U.1    Arbuthnott, G.2
  • 28
  • 31
    • 0030665086 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor prevents death, but not reductions in tyrosine hydroxylase, of injured nigrostriatal neurons in adult rats
    • (1997) J. Comp. Neurol. , vol.388 , pp. 484-494
    • Lu, X.1    Hagg, T.2
  • 32
  • 33
    • 0034526219 scopus 로고    scopus 로고
    • Single or continuous injection of glial cell line-derived neurotrophic factor in the striatum induces recovery of the nigrostriatal dopaminergic system
    • (2000) Neurol. Res. , vol.22 , pp. 832-836
    • Aoi, M.1    Date, I.2    Tomita, S.3    Ohmoto, T.4
  • 34
    • 0034074394 scopus 로고    scopus 로고
    • The effect of intrastriatal single injection of GDNF on the nigrostriatal dopaminergic system in hemiparkinsonian rats: Behavioral and histological studies using two different dosages
    • (2000) Neurosci. Res. , vol.36 , pp. 319-325
    • Aoi, M.1    Date, I.2    Tomita, S.3    Ohmoto, T.4
  • 39
    • 0030950227 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor attenuates behavioural deficits and regulates nigrostriatal dopaminergic and peptidergic markers in 6-hydroxydopamine-lesioned adult rats: Comparison of intraventricular delivery
    • (1997) Neuroscience , vol.78 , pp. 61-72
    • Lapchak, P.A.1    Miller, P.J.2    Collins, F.3    Jiao, S.4
  • 41
    • 0034097605 scopus 로고    scopus 로고
    • Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model
    • (2000) Exp. Neurol. , vol.161 , pp. 503-516
    • Rosenblad, C.1    Kirik, D.2    Björklund, A.3
  • 42
  • 51
  • 54
    • 0034109787 scopus 로고    scopus 로고
    • Promotion of survival and regeneration of nigral dopamine neurons in a rat model of Parkinson's disease after implantation of embryonal carcinoma-derived neurons genetically engineered to produce glial cell factor
    • (2000) J. Neurosurg. , vol.92 , pp. 659-670
    • Nakao, N.1    Yokote, H.2    Nakai, K.3    Itakura, T.4
  • 57
    • 0030795798 scopus 로고    scopus 로고
    • Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson's disease
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8818-8823
    • Bilang-Bleuel, A.1    Revah, F.2    Colin, P.3
  • 61
  • 62
    • 0032708890 scopus 로고    scopus 로고
    • Recombinant adeno-associated viral vector-mediated glial cell line-derived neurotrophic factor gene transfer protects nigral dopamine neurons after onset of progressive degeneration in a rat model of Parkinson's disease
    • (1999) Exp. Neurol. , vol.160 , pp. 205-214
    • Mandel, R.J.1    Snyder, R.O.2    Leff, S.E.3
  • 64
  • 79
    • 0032457981 scopus 로고    scopus 로고
    • Growth/differentiation factor 5 and glial cell line-derived neurotrophic factor enhance survival and function of dopaminergic grafts in a rat model of Parkinson's disease
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 3681-3688
    • Sullivan, A.M.1    Pohl, J.2    Blunt, S.B.3
  • 82
    • 0031812748 scopus 로고    scopus 로고
    • Enhancement of graft survival and sensorimotor behavioral recovery in rats undergoing transplantation with dopaminergic cells exposed to glial cell line-derived neurotrophic factor
    • (1998) J. Neurosurg. , vol.88 , pp. 1088-1095
    • Mehta, V.1    Hong, M.2    Spears, J.3    Mendez, I.4
  • 85
    • 0033559401 scopus 로고    scopus 로고
    • A glial cell line-derived neurotrophic factor-secreting clone of the Schwann cell line SCTM41 enhances survival and fiber outgrowth from embryonic nigral neurons grafted to the striatum and to the lesioned substantia nigra
    • (1999) J. Neurosci. , vol.19 , pp. 2301-2312
    • Wilby, M.J.1    Sinclair, S.R.2    Muir, E.M.3
  • 86
    • 0032192007 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor improves survival of dopaminergic neurons in transplants of fetal ventral mesencephalic tissue
    • (1998) Exp. Neurol. , vol.153 , pp. 195-202
    • Yurek, D.M.1
  • 92
    • 0034099045 scopus 로고    scopus 로고
    • Enhancement of survival of stored dopaminergic cells and promotion of graft survival by exposure of human fetal nigral tissue to glial cell line-derived neurotrophic factor in patients with Parkinson's disease. cases and technical considerations
    • (2000) J. Neurosurg. , vol.92 , pp. 863-869
    • Mendez, I.1    Dagher, A.2    Hong, M.3
  • 98
    • 17144448554 scopus 로고    scopus 로고
    • Rat fetal ventral mesencephalon grown as solid tissue cultures: Influence of culture time and BDNF treatment on dopamine neuron survival and function
    • (1998) Brain Res. , vol.813 , pp. 313-322
    • Hoglinger, G.U.1    Sautter, J.2    Meyer, M.3
  • 100
    • 0029657961 scopus 로고    scopus 로고
    • The survival response of mesencephalic dopaminergic neurons to the neurotrophins BDNF and NT-4 requires priming with serum: Comparison with members of the TGF-beta superfamily and characterization of the serum-free culture system
    • (1996) J. Neural Transm. Suppl. , vol.47 , pp. 247-258
    • Krieglstein, K.1    Maysinger, D.2    Unsicker, K.3
  • 108
    • 0027081071 scopus 로고
    • Protection from 1-methyl-4-phenylpyridinium (MPP+) toxicity and stimulation of regrowth of MPP(+)-damaged dopaminergic fibers by treatment of mesencephalic cultures with EGF and basic FGF
    • (1992) Brain Res. , vol.599 , pp. 83-97
    • Park, T.H.1    Mytilineou, C.2
  • 110
    • 0026042368 scopus 로고
    • The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia
    • (1991) J. Neurosci. , vol.11 , pp. 3070-3078
    • Engele, J.1    Bohn, M.C.2
  • 114
    • 0030918062 scopus 로고    scopus 로고
    • Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: Involvement of the glutathione system
    • (1997) J. Neurochem. , vol.69 , pp. 76-83
    • Hou, J.G.1    Cohen, G.2    Mytilineou, C.3
  • 118
    • 0023865447 scopus 로고
    • Development and survival of neurons in dissociated fetal mesencephalic serum-free cell cultures: II. Modulatory effects of gangliosides
    • (1988) J. Neurosci. , vol.8 , pp. 746-753
    • Leon, A.1    Dal Toso, R.2    Presti, D.3
  • 121
    • 0025265681 scopus 로고
    • Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II
    • (1990) J. Neurosci. , vol.10 , pp. 558-570
    • Knüsel, B.1    Michel, P.P.2    Schwaber, J.S.3    Hefti, F.4
  • 127
    • 0027214522 scopus 로고
    • Trophic actions of transforming growth factor alpha on mesencephalic dopaminergic neurons developing in culture
    • (1993) Neuroscience , vol.55 , pp. 903-918
    • Alexi, T.1    Hefti, F.2
  • 132
    • 0031888498 scopus 로고    scopus 로고
    • Neurotrophins prevent death and differentially affect tyrosine hydroxylase of adult rat nigrostriatal neurons in vivo
    • (1998) Exp. Neurol. , vol.149 , pp. 183-192
    • Hagg, T.1
  • 137
    • 0021051853 scopus 로고
    • Gangliosides increase the survival of lesioned nigral dopamine neurons and favour the recovery of dopaminergic synaptic function in striatum of rats by collateral sprouting
    • (1983) Acta Physiol. Scand. , vol.119 , pp. 347-363
    • Agnati, L.F.1    Fuxe, K.2    Calza, L.3
  • 138
    • 0035148625 scopus 로고    scopus 로고
    • Influence of time in culture and BDNF pretreatment on survival and function of grafted embryonic rat ventral mesencephalon in the 6-OHDA rat model of Parkinson's disease
    • (2001) Exp. Neurol. , vol.167 , pp. 148-157
    • Hoglinger, G.U.1    Widmer, H.R.2    Spenger, C.3
  • 143
    • 0030158340 scopus 로고    scopus 로고
    • Altered motor function and graft survival produced by basic fibroblast growth factor in rats with 6-OHDA lesions and fetal ventral mesencephalic grafts are associated with glial proliferation
    • (1996) Exp. Neurol. , vol.139 , pp. 214-226
    • Zeng, B.Y.1    Jenner, P.2    Marsden, C.D.3
  • 145
    • 0027236053 scopus 로고
    • Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons--II. Effects on nigral transplants in vivo
    • (1993) Neuroscience , vol.56 , pp. 389-398
    • Mayer, E.1    Fawcett, J.W.2    Dunnett, S.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.