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Journal of the American Chemical Society

Volumn 122, Issue 37, 2000, Pages 8890-8897

A novel application of a Pd(0)-catalyzed nucleophilic substitution reaction to the regio- and stereoselective synthesis of lactam analogues of the epothilone natural products

(11) Borzilleri, R M a Zheng, X a Schmidt, R J a Johnson, J A a Kim, S H a DiMarco, J D a Fairchild, C R a Gougoutas, J Z a Lee, F Y F a Long, B H a Vite, G D a

a BRISTOL MYERS SQUIBB (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,11 DIHYDROXY 8,8,10,12,16 PENTAMETHYL 3 [1 METHYL 2 (2 METHYL 4 THIAZOLYL)ETHENYL 4 AZA 17 OXABICYCLO[14.1.0]HEPTADECANE 5,9 DIONE; ANTINEOPLASTIC AGENT; EPOTHILONE A; EPOTHILONE B; EPOTHILONE C; IXABEPILONE; LACTAM; NATURAL PRODUCT; PALLADIUM; TAXANE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CATALYSIS; CHEMICAL REACTION; DRUG SYNTHESIS; EVALUATION; HUMAN; NONHUMAN; REACTION ANALYSIS; REDUCTION; STEREOCHEMISTRY;

EID: 0034692354 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja001899n Document Type: Article

Times cited : (141)

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