Lymphocyte antigen receptor and coreceptor signaling Siena, Italy, November 6-10, 1999

EMBO Journal

Volumn 19, Issue 18, 2000, Pages 4857-4865

  Baldari, Cosima T ^a   Telford, John L ^b   Acuto, Oreste ^c  

^a UNIVERSITY OF SIENA   (Italy)

^b CHIRON VACCINES   (Italy)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR;

ANTIGEN PRESENTATION; B LYMPHOCYTE ACTIVATION; CELL MEMBRANE TRANSPORT; CONFERENCE PAPER; HUMAN; ITALY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANIMAL; B LYMPHOCYTE; CELL DIFFERENTIATION; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY; T LYMPHOCYTE; TIME;

ANIMALS; B-LYMPHOCYTES; CELL DIFFERENTIATION; HUMANS; LYMPHOCYTE ACTIVATION; RECEPTORS, ANTIGEN; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TIME FACTORS;

EID: 0034665044     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

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5. B cells extract and present immobilized antigen: Implications for affinity discrimination
6. Regulation of T cell receptor (TCR) β gene expression by CD3 complex signaling in immature thymocytes: Implications for TCRβ allelic exclusion
7. Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T ceil activation
8. T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-ζ complex, recruits intracellular signaling proteins to the plasma membrane
9. Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76
10. Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development
11. Fetal hemorrhage, platelet dysfunction in SLP-76-deficient mice
12. Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling
13. The CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes
14. Heightened sensitivity of a lattice of membrane receptors
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22. Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases
23. Ig-α cytoplasmic truncation renders immature B cells more sensitive to antigen contact
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26. Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge
27. Dynamic re-distribution of protein kinase D (PKD) as revealed by a GFP-PKD fusion protein: Dissociation from PKD activation
28. CD28 utilizes Vav-1 to enhance of TCR-proximal signaling and NF-AT activation
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30. The SH2 domain containing inositol 5-phosphatase SHIP2 associates to the immunoreceptor tyrosine-based inhibition motif of FcγRIIB in B cells under negative signaling
31. Cytotoxic T lymphocyte antigen 4 (CTLA-4) engagement delivers an inhibitory signal through the membrane-proximal region in the absence if the tyrosine motif in the cytoplasmic tail
32. Deficiency in CD22, a B cell-specific inhibitory receptor is stifficient to predispose to development of high affinity autoantibodies
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34. Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck
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36. Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76
37. SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells
38. Constitutive activation of the Ras/MAP kinase pathway and enhanced TCR signaling by targeting the Shc adaptor to membrane rafts
39. An IgE-dependent secretory response of mast cells can be induced by a glycosphingolipid-specific monoclonal antibody
40. Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development
41. Transient confinement of a glycosylphosphatidylinositol-anchored protein in the plasma membrane
42. Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes
43. Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
44. TCR signaling induces selective exclusion of CD43 from the T cell-antigen-presenting cell contact site
45. Interaction of SLP adaptors with the SH2 domain of Tec family kinases
46. PKCθ is required for TCR induced NF-κB activation in mature but not immature T lymphocytes
47. The B-cell-specific Src-family kinase Blk is dispensable for B-cell development and activation
48. Aberrant B cell development and immune response in mice with a compromised BCR complex
49. Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition
50. RORγT, a thymus-specific isoform of the orphan nuclear receptor RORγ/mTOR, is upregulated by signaling through the pre-T cell receptor and binds to the TEA promoter
51. T lymphocyte costimulation mediated by reorganization of membrane microdomains
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53. Dependence of T cell antigen recognition on the dimensions of an accessory receptor-ligand complex
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56. + double-positive thymocytes in mice with compromised CD3 complex signaling
57. + T-cell lineage fate
58. Essential role of LAT in T cell development
59. The association of Grb2, Gads and phospholipase C-γ1 with phosphorylated LAT tyrosine residues: The effect of tyrosine mutations on T cell antigen receptor-mediated signaling