The CD45 tyrosine phosphatase regulates CD3-induced signal transduction and T cell development in recombinase-deficient mice: Restoration of pre-TCR function by active p56(lck)

European Journal of Immunology

Volumn 29, Issue 8, 1999, Pages 2376-2384

  Pingel, Sabine ^a   Baker, Matthew ^a   Turner, Martin ^a   Holmes, Nick ^b   Alexander, Denis R ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

CD45; lck; Pre TCR; Thymic development; Tyrosine phosphatase

Indexed keywords

CD3 ANTIGEN; CD45 ANTIGEN; MONOCLONAL ANTIBODY; PHOSPHATASE; PROTEIN TYROSINE KINASE; RECOMBINASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

ANIMALS; ANTIGENS, CD3; ANTIGENS, CD4; ANTIGENS, CD45; ANTIGENS, CD8; CELL DIFFERENTIATION; DNA NUCLEOTIDYLTRANSFERASES; HOMEODOMAIN PROTEINS; INTEGRASES; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PHOSPHORYLATION; RECEPTORS, ANTIGEN, T-CELL; RECOMBINASES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TYROSINE;

EID: 0032810006     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4141(199908)29:08<2376::AID-IMMU2376>3.0.CO;2-7     Document Type: Article

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