Cytotoxic T lymphocyte antigen 4 (CTLA-4) engagement delivers an inhibitory signal through the membrane-proximal region in the absence of the tyrosine motif in the cytoplasmic tail

Journal of Experimental Medicine

Volumn 190, Issue 6, 1999, Pages 765-774

  Nakaseko, Chiaki ^a,b   Miyatake, Shoichiro ^c   Iida, Tomohiko ^a   Hara, Satoru ^a,b   Ryo, Abe ^d   Ohno, Hiroshi ^a,e   Saito, Yasushi ^b   Saito, Takashi ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b CHIBA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d TOKYO UNIVERSITY OF SCIENCE   (Japan)

^e KANAZAWA UNIVERSITY   (Japan)

Author keywords

Costimulation; CTLA 4; Negative signal; Tyrosine motif

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 2;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, CD3; ANTIGENS, DIFFERENTIATION; CLONE CELLS; CYTOTOXICITY, IMMUNOLOGIC; IMMUNOCONJUGATES; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MICE; MUTATION; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; T-LYMPHOCYTES, CYTOTOXIC; TYROSINE;

EID: 0033588874     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.6.765     Document Type: Article

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