Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

Immunity

Volumn 11, Issue 5, 1999, Pages 547-554

  Jumaa, Hassan ^a   Wollscheid, Bernd ^a   Mitterer, Michael ^a   Wienands, Jürgen ^a   Reth, Michael ^a   Nielsen, Peter J ^a  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN M; LYMPHOCYTE ANTIGEN RECEPTOR; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE DIFFERENTIATION; BONE MARROW; CALCIUM MOBILIZATION; CELL MATURATION; CELL MUTANT; CONTROLLED STUDY; FLOW CYTOMETRY; GENE DELETION; GENE REARRANGEMENT; IMMUNOGLOBULIN PRODUCTION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOID ORGAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

EID: 0033229798     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80130-2     Document Type: Article

References (37)

1. Allman, D.M., Ferguson, S.E., and Cancro, M.P. (1992). Peripheral B cell maturation: immature peripheral B cells in adults are heat-stable antigen-hi and exhibit unique signaling characteristics. J. Immunol. 149, 2533-2540.
2. Benschop, R.J., and Cambier, J.C. (1999). B cell development: signal transduction by antigen receptors and their surrogates. Curr. Opin. Immunol. 11, 143-151.
3. Campbell, K.S. (1999). Signal transduction from the B cell antigen-receptor. Curr. Opin. Immunol. 11, 256-264.
4. Carsetti, R., Kohler, G., and Lamers, M.C. (1995). Transitional B cells are the target of negative selection in the B cell compartment. J. Exp. Med. 181, 2129-2140.
5. Clements, J.L., Ross-Barta, S.E., Tygrett, L.T., Waldschmidt, T.J., and Koretzky, G.A. (1998a). SLP-76 expression is restricted to hemopoietic cells of monocyte, granulocyte, and T lymphocyte lineage and is regulated during T cell maturation and activation. J. Immunol. 161, 3880-3889.
6. Clements, J.L., Yang, B., Ross-Barta, S.E., Eliason, S.L., Hrstka, R.F., Williamson, R.A., and Koretzky, G.A. (1998b). Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development. Science 281, 416-419.
7. Clements, J.L., Lee, J.R., Gross, B., Yang, B., Olson, J.D., Sandra, A., Watson, S.P., Lentz, S.R., and Koretzky, G.A. (1999). Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice. J. Clin. Invest. 103, 19-25.
8. Fu, C., Turck, C.W., Kurosaki, T., and Chan, A.C. (1998). BLNK: a central linker protein in B cell activation. Immunity 9, 93-103.
9. Goitsuka, R., Fujimura, Y., Mamada, H., Umeda, A., Morimura, T., Uetsuka, K., Doi, K., Tsuji, S., and Kitamura, D. (1998). BASH, a novel signaling molecule preferentially expressed in B cells of the bursa of Fabricius. J. Immunol. 161, 5804-5808.
10. Hardy, R.R., Carmack, C.E., Shinton, S.A., Kemp, J.D., and Hayakawa, K. (1991). Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J. Exp. Med. 173, 1213-1225.
11. Hayashi, S.-I., Kunisada, T., Ogawa, M., Sudo, T., Kodama, H., Suda, T., Nishikawa, S., and Nishikawa, S.-I. (1990). Stepwise progression of B lineage differentiation supported by interleukin 7 and other stromal cell molecules. J. Exp. Med. 171, 1683-1695.
12. Healy, J.I., and Goodnow, C.C. (1998). Positive versus negative signaling by lymphocyte antigen receptors. Annu. Rev. Immunol. 16, 645-670.
13. Ishiai, M., Kurosaki, M., Pappu, R., Okawa, K., Ronko, I., Fu, C., Shibata, M., Iwamatsu, A., Chan, A.C., and Kurosaki, T. (1999). BLNK required for coupling Syk to PLCγ2 and Rac1-JNK in B cells. Immunity 10, 117-125.
14. Jackman, J.K., Motto, D.G., Sun, Q., Tanemoto, M., Turck, C.W., Peltz, G.A., Koretzky, G.A., and Findell, P.R. (1995). Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells. J. Biol. Chem. 270, 7029-7032.
15. Karasuyama, H., Kudo, A., and Melchers, F. (1990). The proteins encoded by the VpreB and λ5 pre-B cell-specific genes can associate with each other and with μ heavy chain. J. Exp. Med. 172, 969-972.
16. Khan, W.N., Alt, F.W., Gerstein, R.M., Malynn, B.A., Larsson, I., Rathbun, G., Davidson, L., Müller, S., Kantor, A.B., and Herzenberg, L.A. (1995). Defective B cell development and function in Btk-deficient mice. Immunity 3, 283-299.
17. Kitamura, D., Roes, J., Kuhn, R., and Rajewsky, K. (1991). A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene. Nature 350, 423-426.
18. Kraal, G., Schomagel, K., Streeter, P.R., Holzmann, B., and Butcher, E.G. (1995). Expression of the mucosal vascular addressin, MAd-CAM-1 on sinus-lining cells in the spleen. Am. J. Pathol. 147, 763-771.
19. Loder, F., Mutschler, B., Ray, R.J., Paige, C.J., Sideras, P., Torres, R., Lamers, M.C., and Carsetti, R. (1999). B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J. Exp. Med. 190, 75-89.
20. MacLennan, I.C. (1998). B-cell receptor regulation of peripheral B cells. Curr. Opin. Immunol. 10, 220-225.
21. Norvell, A., and Monroe, J.G. (1996). Acquisition of surface IgD fails to protect from tolerance-induction. J. Immunol. 156, 1328-1332.
22. Osmond, D.G., Rolink, A., and Melchers, F. (1998). Murine B lymphopoiesis: towards a unified model. Immunol. Today 19, 65-68.
23. Pillai, S. (1999). The chosen few? Positive selection and the generation of naive B lymphocytes. Immunity 10, 493-502.
24. Pivniouk, V., Tsitsikov, E., Swinton, P., Rathbun, G., Alt, F.W., and Geha, R.S. (1998). Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell 94, 229-238.
25. Pivniouk, V.I., Martin, T.R., Lu-Kuo, J.M., Katz, H.R., Oettgen, H.C., and Geha, R.S. (1999). SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells. J. Clin. Invest. 103, 1737-1743.
26. Rajewsky, K. (1996). Clonal selection and learning in the antibody system. Nature 381, 751-758.
27. Rolink, A., Kudo, A., Karasuyama, H., Kikuchi, Y., and Melchers, F. (1991). Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo. EMBO J. 10, 327-336.
28. Rolink, A., and Melchers, F. (1996). B-cell development in the mouse. Immunol. Lett. 54, 157-161.
29. Sater, R.A., Sandel, P.C., and Monroe, J.G. (1998). B cell receptor-induced apoptosis in primary transitional murine B cells: signaling requirements and modulation by T cell help. Int. Immunol. 10, 1673-1682.
30. Takata, M., Homma, Y., and Kurosaki, T. (1995). Requirement of phospholipase C-γ 2 activation in surface immunoglobulin M-induced B cell apoptosis. J. Exp. Med. 182, 907-914.
31. Takata, M., and Kurosaki, T. (1996). A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ 2. J. Exp. Med. 184, 31-40.
32. Townsend, S.E., Weintraub, B.C., and Goodnow, C.C. (1999). Growing up on the streets: why B-cell development differs from T-cell development. Immunol. Today 20, 217-220.
33. Tsubata, T., and Reth, M. (1990). The products of the pre-B cell-specific genes (λ5 and VpreB) and the immunoglobulin μ chain form a complex that is transported to the cell surface. J. Exp. Med. 172, 973-976.
34. Wienands, J., Larbolette, O., and Reth, M. (1996). Evidence for a preformed transducer complex organized by the B cell antigen receptor. Proc. Natl. Acad. Sci. USA 93, 7865-7870.
35. Wienands, J., Schweikert, J., Wollscheid, B., Jumaa, H., Nielsen, P.J., and Reth, M. (1998). SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation. J. Exp. Med. 18, 1-5.
36. Wollscheid, B., Wienands, J., and Reth, M. (1999). The adaptor protein SLP-65/BLNK controls the calcium response in activated B cells. Curr. Top. Microbiol. Immunol. 246, 283-289.
37. Yablonski, D., Kuhne, M.R., Kadlecek, T., and Weiss, A. (1998). Uncoupling of nonreceptor tyrosine kinases from PLC-γ1 in an SLP-76-deficient T cell. Science 281, 413-416.