Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-γ1 and Ras activation

EMBO Journal

Volumn 18, Issue 7, 1999, Pages 1832-1844

  Williams, Brandi L ^a   Irvin, Brenda J ^a   Sutor, Shari L ^b   Chini, Claudia C S ^b   Yacyshyn, Elaine ^b   Wardenburg, Juliane Bubeck ^c   Dalton, Mark ^c   Chan, Andrew C ^c   Abraham, Robert T ^a,b,d  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

NFAT; Signal transduction; T cell antigen receptor; ZAP 70

Indexed keywords

CALCIUM ION; PHOSPHOLIPASE; PROTEIN TYROSINE KINASE; RAS PROTEIN; T LYMPHOCYTE RECEPTOR;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BASE SEQUENCE; BINDING SITES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CARRIER PROTEINS; CATALYTIC DOMAIN; CELL LINE; DNA PRIMERS; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; ISOENZYMES; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHOPROTEINS; POINT MUTATION; PROTEIN-TYROSINE KINASES; RAS PROTEINS; RECEPTORS, ANTIGEN, T-CELL; SRC HOMOLOGY DOMAINS; TRANSCRIPTION FACTORS; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0033118329     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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