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Volumn 164, Issue 4, 2000, Pages 1862-1872

Single-cytokine-producing CD4 memory cells predominate in type 1 and type 2 immunity

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5;

EID: 0034651907     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.4.1862     Document Type: Article
Times cited : (157)

References (57)
  • 1
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann, T. R., H. Cherwinski, M. W. Bond, M. A. Giedlin, and R. L. Coffman. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136:2348.
    • (1986) J. Immunol. , vol.136 , pp. 2348
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 2
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann, T. R., and R. L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145
    • Mosmann, T.R.1    Coffman, R.L.2
  • 3
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., K. M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature 383:787.
    • (1996) Nature , vol.383 , pp. 787
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 4
    • 0031976574 scopus 로고    scopus 로고
    • T lymphocyte differentiation in the periphery
    • Murphy, K. M. 1998. T lymphocyte differentiation in the periphery. Curr. Opin. Immunol. 10:226.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 226
    • Murphy, K.M.1
  • 8
    • 0025290312 scopus 로고
    • Heterogeneity of mouse helper T cells: Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells
    • Street, N. E., J. H. Schumacher, T. A. Fong, H. Bass, D. F. Fiorentino, J. A. Leverah, and T. R. Mosmann. 1990. Heterogeneity of mouse helper T cells: evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells. J. Immunol. 144:1629.
    • (1990) J. Immunol. , vol.144 , pp. 1629
    • Street, N.E.1    Schumacher, J.H.2    Fong, T.A.3    Bass, H.4    Fiorentino, D.F.5    Leverah, J.A.6    Mosmann, T.R.7
  • 9
    • 0013590724 scopus 로고
    • Coexpression of granulocyte-macrophage colony-stimulating factor, γ interferon, and interleukins 3 and 4 is random in murine alloreactive T-lymphocyte clones
    • Kelso, A., and N. M. Gough. 1988. Coexpression of granulocyte-macrophage colony-stimulating factor, γ interferon, and interleukins 3 and 4 is random in murine alloreactive T-lymphocyte clones. Proc. Natl. Acad. Sci. USA 85:9189.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 9189
    • Kelso, A.1    Gough, N.M.2
  • 11
    • 0028982517 scopus 로고
    • Th1 and Th2 subsets: Paradigms lost?
    • Kelso, A. 1995. Th1 and Th2 subsets: paradigms lost? Immunol. Today 16:374.
    • (1995) Immunol. Today , vol.16 , pp. 374
    • Kelso, A.1
  • 13
    • 0028877056 scopus 로고
    • Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations
    • Openshaw, P., E. E. Murphy, N. A. Hosken, V. Maino, K. Davis, K. Murphy, and A. O'Garra. 1995. Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations. J. Exp. Med. 182: 1357.
    • (1995) J. Exp. Med. , vol.182 , pp. 1357
    • Openshaw, P.1    Murphy, E.E.2    Hosken, N.A.3    Maino, V.4    Davis, K.5    Murphy, K.6    O'Garra, A.7
  • 16
    • 0032412441 scopus 로고    scopus 로고
    • Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
    • Agarwal, S., and A. Rao. 1998. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity 9:765.
    • (1998) Immunity , vol.9 , pp. 765
    • Agarwal, S.1    Rao, A.2
  • 19
    • 0030823184 scopus 로고    scopus 로고
    • Replicative senescence of T cells: Does the Hayflick limit lead to immune exhaustion?
    • Effros, R. B., and G. Pawelec. 1997. Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion? Immunol. Today 18:450.
    • (1997) Immunol. Today , vol.18 , pp. 450
    • Effros, R.B.1    Pawelec, G.2
  • 20
    • 0028466130 scopus 로고
    • Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
    • Kearney, E. R., K. A. Pape, D. Y. Loh, and M. K. Jenkins. 1994. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1:327.
    • (1994) Immunity , vol.1 , pp. 327
    • Kearney, E.R.1    Pape, K.A.2    Loh, D.Y.3    Jenkins, M.K.4
  • 22
    • 0030842853 scopus 로고    scopus 로고
    • + T cells from αβ T cell receptor-transgenic mice: A distinct mucosal cytokine phenotype in the absence of transgene-specific antigen
    • + T cells from αβ T cell receptor-transgenic mice: a distinct mucosal cytokine phenotype in the absence of transgene-specific antigen. Eur. J. Immunol. 27:1774.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1774
    • Saparov, A.1    Elson, C.O.2    Devore-Carter, D.3    Bucy, R.P.4    Weaver, C.T.5
  • 24
    • 0032103969 scopus 로고    scopus 로고
    • Generation, persistence, and modulation of ThO effector cells: Role of autocrine IL-4 and IFN-γ
    • Miner, K. T., and M. Croft. 1998. Generation, persistence, and modulation of ThO effector cells: role of autocrine IL-4 and IFN-γ. J. Immunol. 160:5280.
    • (1998) J. Immunol. , vol.160 , pp. 5280
    • Miner, K.T.1    Croft, M.2
  • 25
    • 0032142799 scopus 로고    scopus 로고
    • Regulation of IL-4 expression by activation of individual alleles
    • Riviere, I., M. J. Sunshine, and D. R. Littman. 1998. Regulation of IL-4 expression by activation of individual alleles. Immunity 9:217.
    • (1998) Immunity , vol.9 , pp. 217
    • Riviere, I.1    Sunshine, M.J.2    Littman, D.R.3
  • 27
    • 0030891988 scopus 로고    scopus 로고
    • + T cell frequencies by flow cytometry: Evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency
    • + T cell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency. J. Clin. Invest. 99:1739.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1739
    • Waldrop, S.L.1    Pitcher, C.J.2    Peterson, D.M.3    Maino, V.C.4    Picker, L.J.5
  • 28
    • 0031702771 scopus 로고    scopus 로고
    • Antigen-stimulated IL-4, IL-13 and IFN-γ production by human T cells at a single-cell level
    • de Boer, B. A., Y. E. Fillie, Y. C. Kruize, and M. Yazdanbakhsh. 1998. Antigen-stimulated IL-4, IL-13 and IFN-γ production by human T cells at a single-cell level. Eur. J. Immunol. 28:3154.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 3154
    • De Boer, B.A.1    Fillie, Y.E.2    Kruize, Y.C.3    Yazdanbakhsh, M.4
  • 29
    • 0025339467 scopus 로고
    • Simultaneous production of interleukin 2, interleukin 4 and interferon-γ by activated human blood lymphocytes
    • Andersson, U., J. Andersson, A. Lindfors, K. Wagner, G. Moller, and C. H. Heusser. 1990. Simultaneous production of interleukin 2, interleukin 4 and interferon-γ by activated human blood lymphocytes. Eur. J. Immunol. 20:1591.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 1591
    • Andersson, U.1    Andersson, J.2    Lindfors, A.3    Wagner, K.4    Moller, G.5    Heusser, C.H.6
  • 30
    • 0028267766 scopus 로고
    • Flow cytometric determination of cytokines in activated murine T helper lymphocytes: Expression of interleukin-10 in interferon-γ and in interleukin-4-expressing cells
    • Assenmacher, M., J. Schmitz, and A. Radbruch. 1994. Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-γ and in interleukin-4-expressing cells. Eur. J. Immunol. 24:1097.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1097
    • Assenmacher, M.1    Schmitz, J.2    Radbruch, A.3
  • 31
    • 0028331187 scopus 로고
    • + cell subsets in mice as revealed by single-cell cytokine analysis
    • + cell subsets in mice as revealed by single-cell cytokine analysis. Eur. J. Immunol. 24:549.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 549
    • Kariv, I.1    Hardy, R.R.2    Hayakawa, K.3
  • 32
    • 0029148642 scopus 로고
    • Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry
    • Picker, L. J., M. K. Singh, Z. Zdraveski, J. R. Treer, S. L. Waldrop, P. R. Bergstresser, and V. C. Maino. 1995. Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. Blood 86:1408.
    • (1995) Blood , vol.86 , pp. 1408
    • Picker, L.J.1    Singh, M.K.2    Zdraveski, Z.3    Treer, J.R.4    Waldrop, S.L.5    Bergstresser, P.R.6    Maino, V.C.7
  • 33
    • 0030864552 scopus 로고    scopus 로고
    • Single-cell cytokine profiles in normal humans: Comparison of flow cytometric reagents and stimulation protocols
    • Jason, J., and J. Larned. 1997. Single-cell cytokine profiles in normal humans: comparison of flow cytometric reagents and stimulation protocols. J. Immunol. Methods 207:13.
    • (1997) J. Immunol. Methods , vol.207 , pp. 13
    • Jason, J.1    Larned, J.2
  • 37
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks, C. R., B. A. Freiberg, H. Kupfer, N. Sciaky, and A. Kupfer. 1998. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395:82.
    • (1998) Nature , vol.395 , pp. 82
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 38
    • 0032563231 scopus 로고    scopus 로고
    • Fidelity of T cell activation through multistep T cell receptor ζ phosphorylation
    • Kersh, E. N., A. S. Shaw, and P. M. Allen. 1998. Fidelity of T cell activation through multistep T cell receptor ζ phosphorylation. Science 281:572.
    • (1998) Science , vol.281 , pp. 572
    • Kersh, E.N.1    Shaw, A.S.2    Allen, P.M.3
  • 40
    • 0025286210 scopus 로고
    • Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation
    • Harding, C. V., and E. R. Unanue. 1990. Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation. Nature 346: 574.
    • (1990) Nature , vol.346 , pp. 574
    • Harding, C.V.1    Unanue, E.R.2
  • 45
    • 0023722862 scopus 로고
    • A novel two colour ELISPOT assay. I. Simultaneous detection of distinct types of antibody-secreting cells
    • Czerkinsky, C., Z. Moldoveanu, J. Mestecky, L. A. Nilsson, and O. Ouchterlony. 1988. A novel two colour ELISPOT assay. I. Simultaneous detection of distinct types of antibody-secreting cells. J. Immunol. Methods 115:31.
    • (1988) J. Immunol. Methods , vol.115 , pp. 31
    • Czerkinsky, C.1    Moldoveanu, Z.2    Mestecky, J.3    Nilsson, L.A.4    Ouchterlony, O.5
  • 46
    • 0032521390 scopus 로고    scopus 로고
    • T cells reactive to a single immunodominant self-restricted allopeptide induce skin graft rejection in mice
    • Valujskikh, A., D. Matesic, A. Gilliam, D. Anthony, T. M. Haqqi, and P. S. Heeger. 1998. T cells reactive to a single immunodominant self-restricted allopeptide induce skin graft rejection in mice. J. Clin. Invest 101:1398.
    • (1998) J. Clin. Invest , vol.101 , pp. 1398
    • Valujskikh, A.1    Matesic, D.2    Gilliam, A.3    Anthony, D.4    Haqqi, T.M.5    Heeger, P.S.6
  • 47
    • 0028037162 scopus 로고
    • Molecular analysis of the helper T cell response in murine interstitial nephritis: T cells recognizing an immunodominant epitope use multiple T cell receptor Vβ genes with similarities across CDR3
    • Heeger, P. S., W. E. Smoyer, T. Saad, S. Albert, C. J. Kelly, and E. G. Neilson. 1994. Molecular analysis of the helper T cell response in murine interstitial nephritis: T cells recognizing an immunodominant epitope use multiple T cell receptor Vβ genes with similarities across CDR3. J. Clin. Invest. 94:2084.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2084
    • Heeger, P.S.1    Smoyer, W.E.2    Saad, T.3    Albert, S.4    Kelly, C.J.5    Neilson, E.G.6
  • 49
    • 0026053505 scopus 로고
    • Immunochemical characteristics of the population structure of antibody-producing cells in experimental influenza
    • Dukhin, A. I., I.I. Agafonova, and B. L. Voitsekhovskii. 1991. [Immunochemical characteristics of the population structure of antibody-producing cells in experimental influenza]. Vestn. Akad. Med. Nauk SSSR 14.
    • (1991) Vestn. Akad. Med. Nauk SSSR , vol.14
    • Dukhin, A.I.1    Agafonova, I.I.2    Voitsekhovskii, B.L.3
  • 51
    • 0027959893 scopus 로고
    • Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype
    • Sad, S., and T. R Mosmann. 1994. Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype. J. Immunol. 153:3514.
    • (1994) J. Immunol. , vol.153 , pp. 3514
    • Sad, S.1    Mosmann, T.R.2
  • 53
    • 0032532650 scopus 로고    scopus 로고
    • High antigen density and 1L-2 are required for generation of CD4 effectors secreting Th1 rather than Th0 cytokines
    • Rogers, P. R., G. Huston, and S. L. Swain. 1998. High antigen density and 1L-2 are required for generation of CD4 effectors secreting Th1 rather than Th0 cytokines. J. Immunol. 161:3844.
    • (1998) J. Immunol. , vol.161 , pp. 3844
    • Rogers, P.R.1    Huston, G.2    Swain, S.L.3
  • 54
    • 0029670540 scopus 로고    scopus 로고
    • Induction of TH1 and TH2 immunity in neonatal mice
    • Forsthuber, T., H. C. Yip, and P. V. Lehmann. 1996. Induction of TH1 and TH2 immunity in neonatal mice. Science 271:1728.
    • (1996) Science , vol.271 , pp. 1728
    • Forsthuber, T.1    Yip, H.C.2    Lehmann, P.V.3
  • 55
    • 0028923132 scopus 로고
    • Normal T lymphocytes can express two different T cell receptor β chains: Implications for the mechanism of allelic exclusion
    • Radovan, E., C. Giachino, M. Cella, S. Valitutti, O. Acuto, and A. Lanzavecchia. 1995. Normal T lymphocytes can express two different T cell receptor β chains: implications for the mechanism of allelic exclusion. J. Exp. Med. 181:1587.
    • (1995) J. Exp. Med. , vol.181 , pp. 1587
    • Radovan, E.1    Giachino, C.2    Cella, M.3    Valitutti, S.4    Acuto, O.5    Lanzavecchia, A.6
  • 56
    • 0033577811 scopus 로고    scopus 로고
    • Simultaneous disruption of interleukin. (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses
    • McKenzie, G. J., P. G. Fallon, C. L. Emson, R. K. Grencis, and A. N. McKenzie. 1999. Simultaneous disruption of interleukin. (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses. J. Exp. Med. 189:1565.
    • (1999) J. Exp. Med. , vol.189 , pp. 1565
    • McKenzie, G.J.1    Fallon, P.G.2    Emson, C.L.3    Grencis, R.K.4    McKenzie, A.N.5
  • 57
    • 0032531605 scopus 로고    scopus 로고
    • Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3
    • Zhang, D. H., L. Yang, and A. Ray. 1998. Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3. J. Immunol. 161:3817.
    • (1998) J. Immunol. , vol.161 , pp. 3817
    • Zhang, D.H.1    Yang, L.2    Ray, A.3


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