메뉴 건너뛰기




Volumn 162, Issue 7, 1999, Pages 3942-3949

Adjuvant-guided type-1 and type-2 immunity: Infectious/noninfectious dichotomy defines the class of response

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CYTOKINE; EGG WHITE; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; LYSOZYME;

EID: 0344915162     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (249)

References (76)
  • 1
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann, T. R., and R. L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145
    • Mosmann, T.R.1    Coffman, R.L.2
  • 2
    • 0028982517 scopus 로고
    • Th1 and Th2 subsets: Paradigms lost?
    • Kelso, A. 1995. Th1 and Th2 subsets: paradigms lost? Immunol. Today 16:374.
    • (1995) Immunol. Today , vol.16 , pp. 374
    • Kelso, A.1
  • 4
    • 0026603775 scopus 로고
    • Revisiting and revising suppressor T cells
    • Bloom, B. R., P. Salgame, and B. Diamond. 1992. Revisiting and revising suppressor T cells. Immunol. Today 13:131.
    • (1992) Immunol. Today , vol.13 , pp. 131
    • Bloom, B.R.1    Salgame, P.2    Diamond, B.3
  • 5
    • 43949158538 scopus 로고
    • The Th1-Th2 hypothesis of HIV infection: New insights
    • Clerici. M., and Shearer, G. M. 1994. The Th1-Th2 hypothesis of HIV infection: new insights. Immunol. Today 15:575.
    • (1994) Immunol. Today , vol.15 , pp. 575
    • Clerici, M.1    Shearer, G.M.2
  • 6
    • 77049248972 scopus 로고
    • The mode of action of immunologic adjuvants
    • Freund, J. 1956. The mode of action of immunologic adjuvants. Adv. Tuberc. Res. 7:130.
    • (1956) Adv. Tuberc. Res. , vol.7 , pp. 130
    • Freund, J.1
  • 8
    • 0018704064 scopus 로고
    • Adjuvants and immune regulation by lymphoid cells
    • Waksman, B. H. 1979. Adjuvants and immune regulation by lymphoid cells. Springer Semin. Immunopathol. 2:5.
    • (1979) Springer Semin. Immunopathol. , vol.2 , pp. 5
    • Waksman, B.H.1
  • 9
    • 0027522991 scopus 로고
    • Adjuvant a balance between toxicity and adjuvanticity
    • Gupta, R. K., E. H. Relyveld, and E. B. Lindblad. 1993. Adjuvant a balance between toxicity and adjuvanticity. Vaccine 11:293.
    • (1993) Vaccine , vol.11 , pp. 293
    • Gupta, R.K.1    Relyveld, E.H.2    Lindblad, E.B.3
  • 10
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway, Jr., C. A. 1989. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54:1.
    • (1989) Cold Spring Harb. Symp. Quant. Biol. , vol.54 , pp. 1
    • Janeway C.A., Jr.1
  • 11
    • 0026791975 scopus 로고
    • The immune system evolved to discriminate infectious nonself from noninfectious self
    • Janeway, Jr., C. A. 1992. The immune system evolved to discriminate infectious nonself from noninfectious self. Immunol. Today 13:11.
    • (1992) Immunol. Today , vol.13 , pp. 11
    • Janeway C.A., Jr.1
  • 12
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger, P. 1994. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12:991.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991
    • Matzinger, P.1
  • 14
    • 0023143676 scopus 로고
    • Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
    • Jenkins, M. K., and R. H. Schwartz. 1987. Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo. J. Exp. Med. 165:302.
    • (1987) J. Exp. Med. , vol.165 , pp. 302
    • Jenkins, M.K.1    Schwartz, R.H.2
  • 15
    • 0030831201 scopus 로고    scopus 로고
    • Seeking wisdom in innate immunity
    • Fearon, D. T. 1997. Seeking wisdom in innate immunity. Nature 388:323.
    • (1997) Nature , vol.388 , pp. 323
    • Fearon, D.T.1
  • 16
    • 0029987839 scopus 로고    scopus 로고
    • The instructive role of innate immunity in the acquired immune response
    • Fearon, D. T., and R. M. Locksley. 1996. The instructive role of innate immunity in the acquired immune response. Science 272:50.
    • (1996) Science , vol.272 , pp. 50
    • Fearon, D.T.1    Locksley, R.M.2
  • 18
    • 1842417149 scopus 로고    scopus 로고
    • Tolerance induction and autoimmune encephalomyelitis amelioration after administration of myelin basic protein-derived peplide
    • Marusic, S., and S. Tonegawa. 1997. Tolerance induction and autoimmune encephalomyelitis amelioration after administration of myelin basic protein-derived peplide. J. Exp. Med. 186-507.
    • (1997) J. Exp. Med. , vol.186 , pp. 507
    • Marusic, S.1    Tonegawa, S.2
  • 19
    • 0028466130 scopus 로고
    • Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
    • Kearney, E. R., K. A. Pape, D. Y. Loh, and M. K. Jenkins. 1994. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1:327.
    • (1994) Immunity , vol.1 , pp. 327
    • Kearney, E.R.1    Pape, K.A.2    Loh, D.Y.3    Jenkins, M.K.4
  • 20
    • 0029670540 scopus 로고    scopus 로고
    • Induction of TH1 and TH2 immunity in neonatal mice
    • Forsthuber, T., H. C. Yip, and P. V. Lehmann. 1996. Induction of TH1 and TH2 immunity in neonatal mice. Science 271:1728.
    • (1996) Science , vol.271 , pp. 1728
    • Forsthuber, T.1    Yip, H.C.2    Lehmann, P.V.3
  • 21
    • 0030002897 scopus 로고    scopus 로고
    • Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: Implications lor antibody vs. T cell-mediated autoimmunity
    • Singh, R. R., B. H. Hahn, and H. H. Sercarz. 1996. Neonatal peptide exposure can prime T cells and, upon subsequent immunization, induce their immune deviation: implications lor antibody vs. T cell-mediated autoimmunity. J. Exp. Med. 183-1613.
    • (1996) J. Exp. Med. , vol.183 , pp. 1613
    • Singh, R.R.1    Hahn, B.H.2    Sercarz, H.H.3
  • 22
    • 0030939477 scopus 로고    scopus 로고
    • Neonatal injection of an ovarian peplide induces autoimmune ovarian disease in female mice: Requirement of endogenous neonatal ovaries
    • Garza, K. M., N. D. Griggs, and K. S. K. Tung. 1997. Neonatal injection of an ovarian peplide induces autoimmune ovarian disease in female mice: requirement of endogenous neonatal ovaries. Immunity 6:89.
    • (1997) Immunity , vol.6 , pp. 89
    • Garza, K.M.1    Griggs, N.D.2    Tung, K.S.K.3
  • 23
    • 0031452948 scopus 로고    scopus 로고
    • Determinant spreading of T helper 2 (Th2) responses to pancreatic autoantigens
    • Tian, J., P. V. Lehmann, and D. Kaufmann. 1997. Determinant spreading of T helper 2 (Th2) responses to pancreatic autoantigens. J. Exp. Med. 186-2039.
    • (1997) J. Exp. Med. , vol.186 , pp. 2039
    • Tian, J.1    Lehmann, P.V.2    Kaufmann, D.3
  • 24
    • 0029902003 scopus 로고    scopus 로고
    • Neonatal and early life immune responses lo various forms of vaccine antigens qualitatively differ from adult responses: Predominance of a Th2-biased pattern which persists after adult boosting
    • Barrios, C., P. Brawand, M. Berney, C. Brandt, P.-H., Lambert, and C.-A. Siegrist. 1996. Neonatal and early life immune responses lo various forms of vaccine antigens qualitatively differ from adult responses: predominance of a Th2-biased pattern which persists after adult boosting. Eur. J. Immunol. 26:1489.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1489
    • Barrios, C.1    Brawand, P.2    Berney, M.3    Brandt, C.4    Lambert, P.-H.5    Siegrist, C.-A.6
  • 25
    • 0029584493 scopus 로고
    • Expansion of memory Th2 cells over Th1 cells in neonatally primed mice
    • Chen, A., Q. Gao, and H. H. Field. 1995. Expansion of memory Th2 cells over Th1 cells in neonatally primed mice. Transplantation 60:1187.
    • (1995) Transplantation , vol.60 , pp. 1187
    • Chen, A.1    Gao, Q.2    Field, H.H.3
  • 26
    • 0017097912 scopus 로고
    • An evaluation of a procedure for the isolation of myelin basic protein (BP)
    • Pitts, O. M., A. A. Barrows, and E. D. Day. 1976. An evaluation of a procedure for the isolation of myelin basic protein (BP). Prep. Biochem. 6:239.
    • (1976) Prep. Biochem. , vol.6 , pp. 239
    • Pitts, O.M.1    Barrows, A.A.2    Day, E.D.3
  • 27
    • 0029889464 scopus 로고    scopus 로고
    • Heterogeneous T cell receptor Vβ gene repertoire in murine interstitial nephritis
    • Heeger, P. S., W. E. Smoyer, M. Jones, S. Hopfer, and E. G. Neilson. 1996. Heterogeneous T cell receptor Vβ gene repertoire in murine interstitial nephritis. Kidney Int. 49:1222.
    • (1996) Kidney Int. , vol.49 , pp. 1222
    • Heeger, P.S.1    Smoyer, W.E.2    Jones, M.3    Hopfer, S.4    Neilson, E.G.5
  • 28
    • 0022658283 scopus 로고
    • Murine cutaneous Leishmaniasis: Resistance correlates with the capacity to generate interferon-γ in response to Leishmania antigens in vitro
    • Sadick, M. D., R. M. Locksley, C. Tubbs, and H. V. Raff. 1986. Murine cutaneous Leishmaniasis: resistance correlates with the capacity to generate interferon-γ in response to Leishmania antigens in vitro. J. Immunol. 136:655.
    • (1986) J. Immunol. , vol.136 , pp. 655
    • Sadick, M.D.1    Locksley, R.M.2    Tubbs, C.3    Raff, H.V.4
  • 29
    • 0026664422 scopus 로고
    • Spreading of T-cell immunity to cryptic determinants of an autoantigen
    • Lehmann, P. V., T. Forsthuber, A. Miller, and E. E. Sercarz. 1992. Spreading of T-cell immunity to cryptic determinants of an autoantigen. Nature 358:155.
    • (1992) Nature , vol.358 , pp. 155
    • Lehmann, P.V.1    Forsthuber, T.2    Miller, A.3    Sercarz, E.E.4
  • 30
    • 0026080797 scopus 로고
    • T cell determinant structure: Cores and determinant envelopes in three mouse major histocompalibility complex haplotypes
    • Gammon, G., M. H. Geysen, R. J. Apple, E. Pickett, M. Palmer, M., A. Ametani, and E. E. Sercarz 1991. T cell determinant structure: cores and determinant envelopes in three mouse major histocompalibility complex haplotypes. J. Exp. Med. 173:609.
    • (1991) J. Exp. Med. , vol.173 , pp. 609
    • Gammon, G.1    Geysen, M.H.2    Apple, R.J.3    Pickett, E.4    Palmer, M.5    Ametani, M.A.6    Sercarz, E.E.7
  • 31
    • 0024270846 scopus 로고
    • Down-regulation of homing receptors after T cell activation
    • Jung, T. M., W. M. Gallatin, I. L. Weissman, and M. O. Dailey. 1988. Down-regulation of homing receptors after T cell activation. J. Immunol. 141:4110.
    • (1988) J. Immunol. , vol.141 , pp. 4110
    • Jung, T.M.1    Gallatin, W.M.2    Weissman, I.L.3    Dailey, M.O.4
  • 32
    • 0026517629 scopus 로고
    • + memory T cells from the spleen lack MEL-14, the lymph node homing, receptor
    • + memory T cells from the spleen lack MEL-14, the lymph node homing, receptor. J. Immunol. 148:324.
    • (1992) J. Immunol. , vol.148 , pp. 324
    • Bradley, L.M.1    Atkins, G.G.2    Swain, S.L.3
  • 33
    • 0028927653 scopus 로고
    • Antigen-specific development of primary and memory T cells in vivo
    • McHeyzer-Williams, M. G., and M. M. Davis. 1995. Antigen-specific development of primary and memory T cells in vivo. Science 268:106.
    • (1995) Science , vol.268 , pp. 106
    • McHeyzer-Williams, M.G.1    Davis, M.M.2
  • 34
    • 0028906593 scopus 로고
    • T cell genetic background determines default T helper phenotype development in vitro
    • Hsieh, C.-S., S. E. Macatonia, A O'Garra, and K. M. Murphy. 1995. T cell genetic background determines default T helper phenotype development in vitro, J. Exp. Med. 181:713.
    • (1995) J. Exp. Med. , vol.181 , pp. 713
    • Hsieh, C.-S.1    Macatonia, S.E.2    O'Garra, A.3    Murphy, K.M.4
  • 35
    • 0030932976 scopus 로고    scopus 로고
    • Behavior of visceral Leishmania donovani in an experimentally induced T helper cell 2 (TH2)-associated response model
    • Murray, H. W., J. Hariprashad, and R. L. Coffman. 1997. Behavior of visceral Leishmania donovani in an experimentally induced T helper cell 2 (TH2)-associated response model. J. Exp. Med. 185-867.
    • (1997) J. Exp. Med. , vol.185 , pp. 867
    • Murray, H.W.1    Hariprashad, J.2    Coffman, R.L.3
  • 36
    • 0025924547 scopus 로고
    • Egg deposition is the major stimulus for the production of Th2 cytokines in murine Schistosomiasis mansoni
    • Grzych, J.-E., E. Pearce, A. Cheever, Z. A. Caulada, P. Caspar, S. Heiny, F. Lewis, and A. Sher. 1991. Egg deposition is the major stimulus for the production of Th2 cytokines in murine Schistosomiasis mansoni. J. Immunol. 146: 1322.
    • (1991) J. Immunol. , vol.146 , pp. 1322
    • Grzych, J.-E.1    Pearce, E.2    Cheever, A.3    Caulada, Z.A.4    Caspar, P.5    Heiny, S.6    Lewis, F.7    Sher, A.8
  • 39
    • 0027372064 scopus 로고
    • Mechanism and regulation of immunoglobulin isotype switching
    • Coffman, R. L., D. A. Lebman, and P. Rothman. 1993. Mechanism and regulation of immunoglobulin isotype switching. Adv. Immunol. 54:229.
    • (1993) Adv. Immunol. , vol.54 , pp. 229
    • Coffman, R.L.1    Lebman, D.A.2    Rothman, P.3
  • 40
    • 0025168823 scopus 로고
    • - T cells: IL-4 is essential for induction of antigen-specific antibody responses by TH2 but not TH1 clones
    • - T cells: IL-4 is essential for induction of antigen-specific antibody responses by TH2 but not TH1 clones. Eur. J. Immunol. 20:2219.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 2219
    • DeKruyff, R.H.1    Mosmann, R.R.2    Umetsu, D.T.3
  • 41
    • 2042462430 scopus 로고
    • Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor I
    • Finkelman, F. D., I. M. Katona, J. J. Urban, C. M. Snapper, J. Ohara, J., and W. E. Paul. 1986. Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor I. Proc. Natl. Acad. Sci. USA 83:9675.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 9675
    • Finkelman, F.D.1    Katona, I.M.2    Urban, J.J.3    Snapper, C.M.4    J Ohara, J.5    Paul, W.E.6
  • 42
    • 0018947643 scopus 로고
    • Regulatory role of IgE-binding factors from rat T lympocytes
    • Hirashima, M., J. Yodoi, and K. Ishizaka. 1980. Regulatory role of IgE-binding factors from rat T lympocytes. J. Immunol. 125:2154.
    • (1980) J. Immunol. , vol.125 , pp. 2154
    • Hirashima, M.1    Yodoi, J.2    Ishizaka, K.3
  • 43
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin-4 deficient mice
    • Kuhn, R., K. Rajewsky, and W. Muller. 1991. Generation and analysis of interleukin-4 deficient mice Science 254:707.
    • (1991) Science , vol.254 , pp. 707
    • Kuhn, R.1    Rajewsky, K.2    Muller, W.3
  • 45
    • 0025318862 scopus 로고
    • Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function
    • Daynes, R. A., B. A. Araneo, T. A. Dowell, K. Huang, and D. Dudley. 1990. Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function. J. Exp. Med. 171:979.
    • (1990) J. Exp. Med. , vol.171 , pp. 979
    • Daynes, R.A.1    Araneo, B.A.2    Dowell, T.A.3    Huang, K.4    Dudley, D.5
  • 46
    • 0028058849 scopus 로고
    • The development of effective vaccine adjuvants employing natural regulators of T cell lymphokine production in vivo
    • Daynes, R. A., and B. A. Araneo. 1994. The development of effective vaccine adjuvants employing natural regulators of T cell lymphokine production in vivo. Ann. NY Acad Sup. 730:144.
    • (1994) Ann. NY Acad Sup. , vol.730 , pp. 144
    • Daynes, R.A.1    Araneo, B.A.2
  • 47
    • 0026080859 scopus 로고
    • The distinctive specificity of antigen-specific suppressor T cells
    • Sercarz, E. E., and U. Krzych. 1991. The distinctive specificity of antigen-specific suppressor T cells. Immunol. Today 12:111.
    • (1991) Immunol. Today , vol.12 , pp. 111
    • Sercarz, E.E.1    Krzych, U.2
  • 48
    • 0027230429 scopus 로고
    • Peptide contributes to the specificity of positive selection of CD8 T cells in the thymus
    • Ashton-Rickardt, P. G., L. Van Kaer, T. N. M. Schumacher, H. L. Ploegh, and S. Tonegawa. 1993. Peptide contributes to the specificity of positive selection of CD8 T cells in the thymus. Cell 73:1041.
    • (1993) Cell , vol.73 , pp. 1041
    • Ashton-Rickardt, P.G.1    Van Kaer, L.2    Schumacher, T.N.M.3    Ploegh, H.L.4    Tonegawa, S.5
  • 49
    • 0032526853 scopus 로고    scopus 로고
    • Endogenous myelin basic protein inactivates the high avidity T cell repertoire
    • Targoni O. S., and P. V. Lehmann. 1998. Endogenous myelin basic protein inactivates the high avidity T cell repertoire. J. Exp. Med. 187:2055.
    • (1998) J. Exp. Med. , vol.187 , pp. 2055
    • Targoni, O.S.1    Lehmann, P.V.2
  • 50
    • 0025286210 scopus 로고
    • Quantitation of peptide-class II MHC complexes generated in antigen presenting cells tor T cell stimulation
    • Harding, C. V., and E. R. Unanue. 1990. Quantitation of peptide-class II MHC complexes generated in antigen presenting cells tor T cell stimulation. Nature 346:574.
    • (1990) Nature , vol.346 , pp. 574
    • Harding, C.V.1    Unanue, E.R.2
  • 51
    • 0028017808 scopus 로고
    • A differentials-avidity model for T cell selection
    • P. G. Ashton-Riekardt, and S. Tonegawa. 1994. A differentials-avidity model for T cell selection. Immunol. Today 8:362.
    • (1994) Immunol. Today , vol.8 , pp. 362
    • Ashton-Riekardt, P.G.1    Tonegawa, S.2
  • 52
    • 0017052305 scopus 로고
    • Characterization of suppressor cells involved in regulation of experimental allergic encephalomyelilis
    • Welch. A. M., and R. H. Swanborg. 1976. Characterization of suppressor cells involved in regulation of experimental allergic encephalomyelilis. Eur. J. Immunol. 6:910.
    • (1976) Eur. J. Immunol. , vol.6 , pp. 910
    • Welch, A.M.1    Swanborg, R.H.2
  • 53
    • 0017644801 scopus 로고
    • Suppressor T cells prevent experimental autoimmune encephalomyelitis in mice
    • Bernard, C. C. A. 1977. Suppressor T cells prevent experimental autoimmune encephalomyelitis in mice. Clin. Exp. Immunol. 29:100.
    • (1977) Clin. Exp. Immunol. , vol.29 , pp. 100
    • Bernard, C.C.A.1
  • 54
    • 0017712685 scopus 로고
    • Immmoregulation of experimental allergic encephalomyelitis: Conditions tor induction of suppressor cells and analysis of mechanism
    • Swierkosz, J. E., and R. H. Swanborg. 1977. Immmoregulation of experimental allergic encephalomyelitis: conditions tor induction of suppressor cells and analysis of mechanism. J. Immunol. 4:1501.
    • (1977) J. Immunol. , vol.4 , pp. 1501
    • Swierkosz, J.E.1    Swanborg, R.H.2
  • 55
    • 0017693754 scopus 로고
    • Lymphocyte specificity to protein antigens. I. Characterisation of the antigen-induced in vitro T cell-dependent proliferative response with lymph node cells from primed mice
    • Corradin, G., H. M. Ellinger, and J. M. Chiller. 1977. Lymphocyte specificity to protein antigens. I. Characterisation of the antigen-induced in vitro T cell-dependent proliferative response with lymph node cells from primed mice. J. Immunol. 119:1048.
    • (1977) J. Immunol. , vol.119 , pp. 1048
    • Corradin, G.1    Ellinger, H.M.2    Chiller, J.M.3
  • 56
    • 0025343120 scopus 로고
    • Naive and memory T cells show distinct pathways of lymphocyte reticulation
    • Mackay, C. R., W. L. Marston, and L. Dudler. 1990. Naive and memory T cells show distinct pathways of lymphocyte reticulation. J. Exp. Med. 171:801.
    • (1990) J. Exp. Med. , vol.171 , pp. 801
    • Mackay, C.R.1    Marston, W.L.2    Dudler, L.3
  • 57
    • 0025891695 scopus 로고
    • T-cell memory: The connection between function, phenotype and migration pathways
    • Mackay, C. R. 1991. T-cell memory: the connection between function, phenotype and migration pathways. Immunol. Today 12:189.
    • (1991) Immunol. Today , vol.12 , pp. 189
    • Mackay, C.R.1
  • 58
    • 45549118928 scopus 로고
    • The spleen in lymphocyte migration
    • Pabst, R. 1988. The spleen in lymphocyte migration. Immunol. Today 9:43.
    • (1988) Immunol. Today , vol.9 , pp. 43
    • Pabst, R.1
  • 59
    • 0028464674 scopus 로고
    • Lymphocyte homing and leukocyte rolling and migration are impaired in L-selection-deficient mice
    • Arbones, M. L., D. C. Ord, K. Lev, H. Ratech, C. Maynard-Curry, G. Otten, D. J. Capon, and T. F. Tedder. 7994. Lymphocyte homing and leukocyte rolling and migration are impaired in L-selection-deficient mice. Immunity 1:247.
    • (1994) Immunity , vol.1 , pp. 247
    • Arbones, M.L.1    Ord, D.C.2    Lev, K.3    Ratech, H.4    Maynard-Curry, C.5    Otten, G.6    Capon, D.J.7
  • 60
    • 0014258709 scopus 로고
    • The mode of action of mineral-oil emulsion adjuvants on antibody production in mice
    • Herbert, W. J. 1968. The mode of action of mineral-oil emulsion adjuvants on antibody production in mice. Immunology 14:301.
    • (1968) Immunology , vol.14 , pp. 301
    • Herbert, W.J.1
  • 61
    • 0028970060 scopus 로고
    • Interlcukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
    • Trinchieri, G. 1995. Interlcukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251
    • Trinchieri, G.1
  • 62
    • 0029099391 scopus 로고
    • Effects of IL-12 on immune responses to microbial infections: A key mediator in regulating disease outcome
    • Biron, C. A., and R. T. Gazzinelli. 1995. Effects of IL-12 on immune responses to microbial infections: a key mediator in regulating disease outcome. Curr. Opin. Immun. 7:485.
    • (1995) Curr. Opin. Immun. , vol.7 , pp. 485
    • Biron, C.A.1    Gazzinelli, R.T.2
  • 63
    • 0029991646 scopus 로고    scopus 로고
    • Epicutaneous exposure lo protein antigen induces a predominant Th2-like response with high IgE production in mice
    • Wang, L.-F., J.-Y. Lin, K. H Hsieh, and R.-H. Lin. 1996. Epicutaneous exposure lo protein antigen induces a predominant Th2-like response with high IgE production in mice. J. Immunol. 156:4079.
    • (1996) J. Immunol. , vol.156 , pp. 4079
    • Wang, L.-F.1    Lin, J.-Y.2    Hsieh, K.H.3    Lin, R.-H.4
  • 65
    • 0029923430 scopus 로고    scopus 로고
    • Nasal administration of glutamate decarboxylase (GAD65) peplides induces Th2 responses and prevents murine insulin-dependent diabetes
    • Tian, J., M. A. Atkinson, M. Clare-Salzler, A. Herschenfeld, T. Forsthuber, P. V. Lehniann, and D. L. Kaufman. 1996. Nasal administration of glutamate decarboxylase (GAD65) peplides induces Th2 responses and prevents murine insulin-dependent diabetes. J. Exp. Med. 183:1561.
    • (1996) J. Exp. Med. , vol.183 , pp. 1561
    • Tian, J.1    Atkinson, M.A.2    Clare-Salzler, M.3    Herschenfeld, A.4    Forsthuber, T.5    Lehniann, P.V.6    Kaufman, D.L.7
  • 67
    • 0000060327 scopus 로고    scopus 로고
    • In vivo microbial stimulation induces rapid CD40 ligand-independent production of interfeukin 12 by dendritic cells and their redistribution to T cell areas
    • Reis e Sousa, C., S. Hieny, T. Scharton-Kersten, D. Jankovic, H. Charest, R. N. Germain, and A. Sher. 1997. In vivo microbial stimulation induces rapid CD40 ligand-independent production of interfeukin 12 by dendritic cells and their redistribution to T cell areas. J. Exp. Med. 186:1819.
    • (1997) J. Exp. Med. , vol.186 , pp. 1819
    • Reis E Sousa, C.1    Hieny, S.2    Scharton-Kersten, T.3    Jankovic, D.4    Charest, H.5    Germain, R.N.6    Sher, A.7
  • 68
    • 0029859871 scopus 로고    scopus 로고
    • Type 1 and type-2 cylokine dysregulation in human infectious, neoplastic, and inflammatory diseases
    • Lucey, D. R., M. Clerici, and G. M. Shearer. 1996. Type 1 and type-2 cylokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin. Microbiol. Rev. 9:532.
    • (1996) Clin. Microbiol. Rev. , vol.9 , pp. 532
    • Lucey, D.R.1    Clerici, M.2    Shearer, G.M.3
  • 69
    • 0025082313 scopus 로고
    • Generation of interleukin-4 (IL-4) producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
    • LeGros, G., S. Z. Ben-Sasson, R. Seder, F. D. Finkelman, and W. Paul. 1990. Generation of interleukin-4 (IL-4) producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J. Exp. Med. 172:921.
    • (1990) J. Exp. Med. , vol.172 , pp. 921
    • LeGros, G.1    Ben-Sasson, S.Z.2    Seder, R.3    Finkelman, F.D.4    Paul, W.5
  • 70
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • Swain, S. L., A. D. Weinberg, M. English, and B. Huston. 1990. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 145:3796.
    • (1990) J. Immunol. , vol.145 , pp. 3796
    • Swain, S.L.1    Weinberg, A.D.2    English, M.3    Huston, B.4
  • 73
    • 0030613651 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides provide a danger signal and act as adjuvants that switch on Th1 immunity
    • Chu, R. S., O. S. Targoni, A. M. Krieg, P. V. Lehmann, and C. V. Harding. 1997. CpG oligodeoxynucleotides provide a danger signal and act as adjuvants that switch on Th1 immunity. J. Exp. Med. 186:1623.
    • (1997) J. Exp. Med. , vol.186 , pp. 1623
    • Chu, R.S.1    Targoni, O.S.2    Krieg, A.M.3    Lehmann, P.V.4    Harding, C.V.5
  • 74
    • 0028518985 scopus 로고
    • Generation and in vivo persistence of polarized Th1 and Th2 memory cells
    • Swain, S. L. 1994. Generation and in vivo persistence of polarized Th1 and Th2 memory cells. Immunity 1:543.
    • (1994) Immunity , vol.1 , pp. 543
    • Swain, S.L.1
  • 75
    • 0029788704 scopus 로고    scopus 로고
    • IL-12 unmasks latent autoimmune disease in resistant mice
    • Segal, B. M., and E. M. Shevach. 1996. IL-12 unmasks latent autoimmune disease in resistant mice. J. Exp. Med. 183:771.
    • (1996) J. Exp. Med. , vol.183 , pp. 771
    • Segal, B.M.1    Shevach, E.M.2
  • 76
    • 0031014668 scopus 로고    scopus 로고
    • The inverse association between tuberculin responses and alopic disorder
    • Shirakawa, T., T. Enomoto, S.-I. Shimazu, and J. M. Hopkin. 1997. The inverse association between tuberculin responses and alopic disorder. Science 275:77.
    • (1997) Science , vol.275 , pp. 77
    • Shirakawa, T.1    Enomoto, T.2    Shimazu, S.-I.3    Hopkin, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.