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Volumn 142, Issue 2, 2000, Pages 113-138

Growth factors in gliomas revisited

Author keywords

Epidermal growth factor (EGF); erbB, vascular endothelial growth factor (VEGF); Fibroblast growth factor (FGF); Glioma; Growth factors; Hepatocyte growth factor (HGF); Insulin like growth factor (IGF); Oncogenes; Platelet derived growth factor (PDGF); Therapy

Indexed keywords

4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; BASIC FIBROBLAST GROWTH FACTOR; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; LEFLUNOMIDE; MUTANT PROTEIN; NEU DIFFERENTIATION FACTOR; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; SCATTER FACTOR; SOMATOMEDIN; TRANSFORMING GROWTH FACTOR BETA; TYROSINE KINASE RECEPTOR; VASCULOTROPIN;

EID: 0033952759     PISSN: 00016268     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007010050015     Document Type: Review
Times cited : (44)

References (358)
  • 1
    • 0008919783 scopus 로고    scopus 로고
    • Treatment of patients with malignant astrocytomas using subcutaneously implanted diffusion chambers containing autologous tumour suspensions preincubated with IGF-1R antisense DNA
    • San Francisco, CA, Abstract No. 2
    • Aiken R, Andrews D, Resnicoff M, Baserga R (1998) Treatment of patients with malignant astrocytomas using subcutaneously implanted diffusion chambers containing autologous tumour suspensions preincubated with IGF-1R antisense DNA. Society for Neuro-Oncology, Third Annual Scientific Meeting, San Francisco, CA, Abstract No. 2
    • (1998) Society for Neuro-oncology, Third Annual Scientific Meeting
    • Aiken, R.1    Andrews, D.2    Resnicoff, M.3    Baserga, R.4
  • 2
    • 0029053716 scopus 로고
    • Cooperative signaling of erbb3 and erbb2 in neoplastic transformation and human mammary carcinomas
    • Alimandi M, Romano A, Curia MC, Muraro R, Fedi P, Aaronson SA, Di Fiore PP et al (1995) Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene 10: 1813-1821
    • (1995) Oncogene , vol.10 , pp. 1813-1821
    • Alimandi, M.1    Romano, A.2    Curia, M.C.3    Muraro, R.4    Fedi, P.5    Aaronson, S.A.6    Di Fiore, P.P.7
  • 3
    • 0026575130 scopus 로고
    • Expression of insulin-like growth factors I and II and their receptor mRNAs in primary human astrocytomas and meningiomas; in vivo studies using in situ hybridization and immunocytochemistry
    • Antoniades HN, Galanopoulos T, Neville-Golden J, Maxwell M (1992) Expression of insulin-like growth factors I and II and their receptor mRNAs in primary human astrocytomas and meningiomas; in vivo studies using in situ hybridization and immunocytochemistry. Int J Cancer 50: 215-222
    • (1992) Int J Cancer , vol.50 , pp. 215-222
    • Antoniades, H.N.1    Galanopoulos, T.2    Neville-Golden, J.3    Maxwell, M.4
  • 4
    • 0032579405 scopus 로고    scopus 로고
    • Constitutive activation of c-Jun N-terminal kinase by a mutant epidermal growth factor receptor
    • Antonyak MA, Moscatello DK, Wong AJ (1998) Constitutive activation of c-Jun N-terminal kinase by a mutant epidermal growth factor receptor. J Biol Chem 273: 2817-2822
    • (1998) J Biol Chem , vol.273 , pp. 2817-2822
    • Antonyak, M.A.1    Moscatello, D.K.2    Wong, A.J.3
  • 5
    • 0028827625 scopus 로고
    • Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
    • Asahara T, Bauters C, Zheng LP, Takeshita S, Bunting S, Ferrara N, Symes JF et al (1995) Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo. Circulation 92: II365-II371
    • (1995) Circulation , vol.92
    • Asahara, T.1    Bauters, C.2    Zheng, L.P.3    Takeshita, S.4    Bunting, S.5    Ferrara, N.6    Symes, J.F.7
  • 6
    • 0030806638 scopus 로고    scopus 로고
    • Monoclonal antibodies to growth factors and growth factor receptors: Their diagnostic and therapeutic potential in brain tumours
    • Ashley DM, Batra SK, Bigner DD (1997) Monoclonal antibodies to growth factors and growth factor receptors: their diagnostic and therapeutic potential in brain tumours. J Neurooncol 35: 259-273
    • (1997) J Neurooncol , vol.35 , pp. 259-273
    • Ashley, D.M.1    Batra, S.K.2    Bigner, D.D.3
  • 8
    • 0028890744 scopus 로고
    • The insulin-like growth factor I receptor: A key to tumour growth?
    • Baserga R (1995) The insulin-like growth factor I receptor: a key to tumour growth? Cancer Res 55: 249-252
    • (1995) Cancer Res , vol.55 , pp. 249-252
    • Baserga, R.1
  • 10
    • 0028880017 scopus 로고
    • Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)
    • Bates P, Fisher R, Ward A, Richardson L, Hill DJ, Graham CF (1995) Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II). Br J Cancer 72: 1189-1193
    • (1995) Br J Cancer , vol.72 , pp. 1189-1193
    • Bates, P.1    Fisher, R.2    Ward, A.3    Richardson, L.4    Hill, D.J.5    Graham, C.F.6
  • 11
    • 0028863853 scopus 로고
    • Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene
    • Batra SK, Castelino-Prabhu S, Wikstrand CJ, Zhu X, Humphrey PA, Friedman HS, Bigner DD (1995) Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene. Cell Growth Differ 6: 1251-1259
    • (1995) Cell Growth Differ , vol.6 , pp. 1251-1259
    • Batra, S.K.1    Castelino-Prabhu, S.2    Wikstrand, C.J.3    Zhu, X.4    Humphrey, P.A.5    Friedman, H.S.6    Bigner, D.D.7
  • 13
    • 0027445743 scopus 로고
    • Autocrine growth regulation in neuroectodermal tumours as detected with oligodeoxynucleolide antisense molecules
    • Behl C, Winkler J, Bogdahn U, Meixensberger J, Schligensiepen KH, Brysch W (1993) Autocrine growth regulation in neuroectodermal tumours as detected with oligodeoxynucleolide antisense molecules. Neurosurgery 33: 679-684
    • (1993) Neurosurgery , vol.33 , pp. 679-684
    • Behl, C.1    Winkler, J.2    Bogdahn, U.3    Meixensberger, J.4    Schligensiepen, K.H.5    Brysch, W.6
  • 14
    • 0026713797 scopus 로고
    • The v-sis oncogene product but not platelet-derived growth factor (PDGF) A homodimers activate PDGF alpha and beta receptors intracellularly and initiate cellular transformation
    • Bejcek BE, Hoffman RM, Lipps D, Li DY, Mitchell CA, Majerus PW, Deuel TF (1992) The v-sis oncogene product but not platelet-derived growth factor (PDGF) A homodimers activate PDGF alpha and beta receptors intracellularly and initiate cellular transformation. J Biol Chem 267: 3289-3293
    • (1992) J Biol Chem , vol.267 , pp. 3289-3293
    • Bejcek, B.E.1    Hoffman, R.M.2    Lipps, D.3    Li, D.Y.4    Mitchell, C.A.5    Majerus, P.W.6    Deuel, T.F.7
  • 15
    • 0024463508 scopus 로고
    • Transformation by v-sis occurs by an internal autoactivation mechanism
    • Bejcek BE, Li DY, Deuel TF (1989) Transformation by v-sis occurs by an internal autoactivation mechanism. Science 245: 1496-1499
    • (1989) Science , vol.245 , pp. 1496-1499
    • Bejcek, B.E.1    Li, D.Y.2    Deuel, T.F.3
  • 16
    • 0026755385 scopus 로고
    • Recombinant human stem cell factor stimulates growth of a human glioblastoma cell line expression c-kit protooncogene
    • Berdel WE, De Vos S, Maurer J, Oberberg D, von Marschall Z, Schroeder JK, Li J et al (1992) Recombinant human stem cell factor stimulates growth of a human glioblastoma cell line expression c-kit protooncogene. Cancer Res 52: 3502-4398
    • (1992) Cancer Res , vol.52 , pp. 3502-4398
    • Berdel, W.E.1    De Vos, S.2    Maurer, J.3    Oberberg, D.4    Von Marschall, Z.5    Schroeder, J.K.6    Li, J.7
  • 17
    • 0342350445 scopus 로고
    • Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin
    • Betsholtz C, Johnsson A, Heldin CH, Westermark B (1986) Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin. Proc Natl Acad Sci USA 83: 6440-6444
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6440-6444
    • Betsholtz, C.1    Johnsson, A.2    Heldin, C.H.3    Westermark, B.4
  • 18
    • 0022447025 scopus 로고
    • Dna sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines
    • Betsholtz C, Johnsson A, Heldin CH, Westermark B, Lind P, Urdea MS, Eddy R et al (1986) cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines. Nature 320: 695-699
    • (1986) Nature , vol.320 , pp. 695-699
    • Betsholtz, C.1    Johnsson, A.2    Heldin, C.H.3    Westermark, B.4    Lind, P.5    Urdea, M.S.6    Eddy, R.7
  • 21
    • 0024399070 scopus 로고
    • Immunosuppression and transforming growth factor-beta in glioblastoma. Preferential production of transforming growth factor-beta 2
    • Bodmer S, Strommer K, Frei K, Siepl C, de Tribolet N, Heid I (1989) Immunosuppression and transforming growth factor-beta in glioblastoma. Preferential production of transforming growth factor-beta 2. J Immunol 143: 3222-3229
    • (1989) J Immunol , vol.143 , pp. 3222-3229
    • Bodmer, S.1    Strommer, K.2    Frei, K.3    Siepl, C.4    De Tribolet, N.5    Heid, I.6
  • 22
    • 0025142474 scopus 로고
    • Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells
    • Bogler O, Wren D, Barnett SC, Land H, Noble M (1990) Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells. Proc Natl Acad Sci USA 87: 6368-6372
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6368-6372
    • Bogler, O.1    Wren, D.2    Barnett, S.C.3    Land, H.4    Noble, M.5
  • 23
    • 0029816983 scopus 로고    scopus 로고
    • Complete inhibition of angiogenesis and growth of microtumours by anti-vascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital videomicroscopy
    • Borgstrom P, Hillan KJ, Sriramarao P, Ferrara N (1996) Complete inhibition of angiogenesis and growth of microtumours by anti-vascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res 56: 4032-4039
    • (1996) Cancer Res , vol.56 , pp. 4032-4039
    • Borgstrom, P.1    Hillan, K.J.2    Sriramarao, P.3    Ferrara, N.4
  • 26
    • 0026599333 scopus 로고
    • Malignant astrocytomas treated with iodine-125 labeled monoclonal antibody 425 against epidermal growth factor receptor: A phase II trial
    • Brady LW, Miyamoto C, Woo DV, Rackover M, Emrich J, Bender H, Dadparvar S et al (1992) Malignant astrocytomas treated with iodine-125 labeled monoclonal antibody 425 against epidermal growth factor receptor: a phase II trial. Int J Radiat Oncol Biol Phys 22: 225-230
    • (1992) Int J Radiat Oncol Biol Phys , vol.22 , pp. 225-230
    • Brady, L.W.1    Miyamoto, C.2    Woo, D.V.3    Rackover, M.4    Emrich, J.5    Bender, H.6    Dadparvar, S.7
  • 27
    • 0032930759 scopus 로고    scopus 로고
    • Type-2 IGF receptor: A multi-ligand binding protein
    • Braulke T (1999) Type-2 IGF receptor: a multi-ligand binding protein. Horm Metab Res 31: 242-246
    • (1999) Horm Metab Res , vol.31 , pp. 242-246
    • Braulke, T.1
  • 28
    • 0030721588 scopus 로고    scopus 로고
    • Basic fibroblast growth factor expression as a predictor of prognosis in pediatric high-grade gliomas
    • Bredel M, Pollack IF, Campbell JW, Hamilton RL (1997) Basic fibroblast growth factor expression as a predictor of prognosis in pediatric high-grade gliomas. Clin Cancer Res 3: 2157-2164
    • (1997) Clin Cancer Res , vol.3 , pp. 2157-2164
    • Bredel, M.1    Pollack, I.F.2    Campbell, J.W.3    Hamilton, R.L.4
  • 29
    • 0031834918 scopus 로고    scopus 로고
    • Inhibition of ras and related G proteins as a therapeutic strategy for blocking malignant glioma growth
    • Bredel M, Pollack IF, Freund JM, Hamilton AD, Sebti SM (1998) Inhibition of ras and related G proteins as a therapeutic strategy for blocking malignant glioma growth. Neurosurgery 43: 124-132
    • (1998) Neurosurgery , vol.43 , pp. 124-132
    • Bredel, M.1    Pollack, I.F.2    Freund, J.M.3    Hamilton, A.D.4    Sebti, S.M.5
  • 30
    • 0028868619 scopus 로고
    • Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development
    • Breier G, Clauss M, Risau W (1995) Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development. Dev Dyn 204: 228-239
    • (1995) Dev Dyn , vol.204 , pp. 228-239
    • Breier, G.1    Clauss, M.2    Risau, W.3
  • 31
    • 0015291143 scopus 로고
    • Tumour angiogenesis: A quantitative method for histologic grading
    • Brem S, Cotran R, Folkman J (1972) Tumour angiogenesis: a quantitative method for histologic grading. J Natl Cancer Inst 48: 347-356
    • (1972) J Natl Cancer Inst , vol.48 , pp. 347-356
    • Brem, S.1    Cotran, R.2    Folkman, J.3
  • 32
    • 0026481269 scopus 로고
    • Immunolocalization of basic fibroblast growth factor to the microvasculature of human brain tumours
    • Brem S, Tsanaclis AM, Gately S, Gross JL, Herblin WF (1992) Immunolocalization of basic fibroblast growth factor to the microvasculature of human brain tumours. Cancer 70: 2673-2680
    • (1992) Cancer , vol.70 , pp. 2673-2680
    • Brem, S.1    Tsanaclis, A.M.2    Gately, S.3    Gross, J.L.4    Herblin, W.F.5
  • 33
    • 0032525784 scopus 로고    scopus 로고
    • The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system
    • Britsch S, Li L, Kirchhoff S, Theuring F, Brinkmann V, Birchmeier C, Riethmacher D (1998) The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system. Genes Dev 12: 1825-1836
    • (1998) Genes Dev , vol.12 , pp. 1825-1836
    • Britsch, S.1    Li, L.2    Kirchhoff, S.3    Theuring, F.4    Brinkmann, V.5    Birchmeier, C.6    Riethmacher, D.7
  • 36
    • 0023513893 scopus 로고
    • Vascular permeability induced by protein product of malignant brain tumours: Inhibition by dexamethasone
    • Bruce JN, Criscuolo GR, Merrill MJ, Moquin RR, Blacklock J, B., Oldfield E, H. (1987) Vascular permeability induced by protein product of malignant brain tumours: inhibition by dexamethasone. J Neurosurg 67: 880-884
    • (1987) J Neurosurg , vol.67 , pp. 880-884
    • Bruce, J.N.1    Criscuolo, G.R.2    Merrill, M.J.3    Moquin, R.R.4    Blacklock, J.B.5    Oldfield, E.6
  • 38
    • 0026722243 scopus 로고
    • Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth
    • M.F.
    • Bussolino F, Di R, M.F., Ziche M, Bocchietto E, Olivero M, Naldini L, Gaudino G et al (1992) Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. J Cell Biol 119: 629-641
    • (1992) J Cell Biol , vol.119 , pp. 629-641
    • Bussolino, F.1    Di, R.2    Ziche, M.3    Bocchietto, E.4    Olivero, M.5    Naldini, L.6    Gaudino, G.7
  • 39
    • 0030221375 scopus 로고    scopus 로고
    • GGF/neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors
    • Canoll PD, Musacchio JM, Hardy R, Reynolds R, Marchionni MA, Salzer JL (1996) GGF/neuregulin is a neuronal signal that promotes the proliferation and survival and inhibits the differentiation of oligodendrocyte progenitors. Neuron 17: 229-243
    • (1996) Neuron , vol.17 , pp. 229-243
    • Canoll, P.D.1    Musacchio, J.M.2    Hardy, R.3    Reynolds, R.4    Marchionni, M.A.5    Salzer, J.L.6
  • 40
    • 0028176477 scopus 로고
    • A neu acquaintance for erbB3 and erbB4: A role for receptor heterodimerization in growth signaling
    • Carraway KLr, Cantley LC (1994) A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling. Cell 78: 5-8
    • (1994) Cell , vol.78 , pp. 5-8
    • Carraway, K.Lr.1    Cantley, L.C.2
  • 42
    • 0028084891 scopus 로고
    • Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis
    • Chen P, Gupta K, Wells A (1994) Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis. J Cell Biol 124: 547-555
    • (1994) J Cell Biol , vol.124 , pp. 547-555
    • Chen, P.1    Gupta, K.2    Wells, A.3
  • 43
    • 0028998155 scopus 로고
    • Modification of human glioma locomotion in vitro by cytokines EGF, bFGF, PDGFbb, NGF, and TNF alpha
    • Chicoine MR, Madsen CL, Silbergeld DL (1995) Modification of human glioma locomotion in vitro by cytokines EGF, bFGF, PDGFbb, NGF, and TNF alpha. Neurosurgery 36: 1165-1171
    • (1995) Neurosurgery , vol.36 , pp. 1165-1171
    • Chicoine, M.R.1    Madsen, C.L.2    Silbergeld, D.L.3
  • 44
    • 0021187645 scopus 로고
    • Nucleotide sequence analysis identifiesthe human c-sis proto-oncogene as a structural gene for plateled-derived growth factor
    • Chiu IM, Reddy EP, Givol D, Robbins KC, Tronick SR, Aaronson SA (1984) Nucleotide sequence analysis identifiesthe human c-sis proto-oncogene as a structural gene for plateled-derived growth factor. Cell 37: 123-129
    • (1984) Cell , vol.37 , pp. 123-129
    • Chiu, I.M.1    Reddy, E.P.2    Givol, D.3    Robbins, K.C.4    Tronick, S.R.5    Aaronson, S.A.6
  • 45
    • 0030787340 scopus 로고    scopus 로고
    • Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII)
    • Chu CT, Everiss KD, Wikstrand CJ, Batra SK, Kung HJ, Bigner D (1997) Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII). Biochem J 324: 855-861
    • (1997) Biochem J , vol.324 , pp. 855-861
    • Chu, C.T.1    Everiss, K.D.2    Wikstrand, C.J.3    Batra, S.K.4    Kung, H.J.5    Bigner, D.6
  • 46
    • 0023791610 scopus 로고
    • DNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules
    • Claesson-Welsh L, Eriksson A, Moren A, Severinsson L, Ek B, Ostman A, Betsholtz C et al (1988) cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules. Mol Cell Biol 8: 3476-3486
    • (1988) Mol Cell Biol , vol.8 , pp. 3476-3486
    • Claesson-Welsh, L.1    Eriksson, A.2    Moren, A.3    Severinsson, L.4    Ek, B.5    Ostman, A.6    Betsholtz, C.7
  • 47
    • 0022340293 scopus 로고
    • Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis
    • Collins T, Ginsburg D, Boss JM, Orkin SH, Pober JS (1985) Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis. Nature 316: 748-750
    • (1985) Nature , vol.316 , pp. 748-750
    • Collins, T.1    Ginsburg, D.2    Boss, J.M.3    Orkin, S.H.4    Pober, J.S.5
  • 48
    • 0028185246 scopus 로고
    • Epidermal growth factor receptor gene and its transcripts in glioblastomas
    • Collins VP (1994) Epidermal growth factor receptor gene and its transcripts in glioblastomas. Recent Results Cancer Res 135: 17-24
    • (1994) Recent Results Cancer Res , vol.135 , pp. 17-24
    • Collins, V.P.1
  • 49
    • 0029398189 scopus 로고
    • Gene amplification in human gliomas
    • Collins VP (1995) Gene amplification in human gliomas. Glia 15: 289-296
    • (1995) Glia , vol.15 , pp. 289-296
    • Collins, V.P.1
  • 50
    • 0025275078 scopus 로고
    • Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor
    • Conn G, Bayne ML, Soderman DD, Kwok PW, Sullivan KA, Palisi TM, Hope DA et al (1990) Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor. Proc Natl Acad Sci USA 87: 2628-2632
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2628-2632
    • Conn, G.1    Bayne, M.L.2    Soderman, D.D.3    Kwok, P.W.4    Sullivan, K.A.5    Palisi, T.M.6    Hope, D.A.7
  • 51
    • 0029074334 scopus 로고
    • Suramin inhibits C6 glioma-induced angiogenesis in vitro
    • Coomber BL (1995) Suramin inhibits C6 glioma-induced angiogenesis in vitro. J Cell Biochem 58: 199-207
    • (1995) J Cell Biochem , vol.58 , pp. 199-207
    • Coomber, B.L.1
  • 52
    • 0028362024 scopus 로고
    • A functional insulin-like growth factor i receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor
    • Coppola D, Ferber A, Miura M, Sell C, D'Ambrosio C, Rubin R, Baserga R (1994) A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor. Mol Cell Biol 14: 4588-4595
    • (1994) Mol Cell Biol , vol.14 , pp. 4588-4595
    • Coppola, D.1    Ferber, A.2    Miura, M.3    Sell, C.4    D'Ambrosio, C.5    Rubin, R.6    Baserga, R.7
  • 53
    • 0023680176 scopus 로고
    • Further characterization of malignant glioma-derived vascular permeability factor
    • Criscuolo GR, Merrill MJ, Oldfield EH (1988) Further characterization of malignant glioma-derived vascular permeability factor. J Neurosurg 69: 254-262
    • (1988) J Neurosurg , vol.69 , pp. 254-262
    • Criscuolo, G.R.1    Merrill, M.J.2    Oldfield, E.H.3
  • 54
    • 0032500675 scopus 로고    scopus 로고
    • Differential signaling by the epidermal growth factor-like growth factors neuregulin-1 and neuregulin-2
    • Crovello CS, Lai C, Cantley LC, Carraway KLr (1998) Differential signaling by the epidermal growth factor-like growth factors neuregulin-1 and neuregulin-2. J Biol Chem 273: 26954-26961
    • (1998) J Biol Chem , vol.273 , pp. 26954-26961
    • Crovello, C.S.1    Lai, C.2    Cantley, L.C.3    Carraway, K.Lr.4
  • 56
    • 0019795138 scopus 로고
    • A human one gene homologous to the transforming gene (v-sis) of simian sarcoma virus
    • Dalla-Favera R, Gelmann EP, Gallo RC, Wong-Staal F (1981) A human one gene homologous to the transforming gene (v-sis) of simian sarcoma virus. Nature 292: 31-35
    • (1981) Nature , vol.292 , pp. 31-35
    • Dalla-Favera, R.1    Gelmann, E.P.2    Gallo, R.C.3    Wong-Staal, F.4
  • 57
    • 0030806074 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms
    • Damert A, Machein M, Breier G, Fujita MQ, Hanahan D, Risau W, Plate KH (1997) Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms. Cancer Res 57: 3860-3864
    • (1997) Cancer Res , vol.57 , pp. 3860-3864
    • Damert, A.1    Machein, M.2    Breier, G.3    Fujita, M.Q.4    Hanahan, D.5    Risau, W.6    Plate, K.H.7
  • 58
    • 0023477137 scopus 로고
    • Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family
    • de Martin R, Haendler B, Hofer-Warbinek R, Gaugitsch H, Wrann M, Schlusener H, Seifert JM et al (1987) Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family. EMBO J 6: 3673-3677
    • (1987) EMBO J , vol.6 , pp. 3673-3677
    • De Martin, R.1    Haendler, B.2    Hofer-Warbinek, R.3    Gaugitsch, H.4    Wrann, M.5    Schlusener, H.6    Seifert, J.M.7
  • 59
    • 0026572345 scopus 로고
    • The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
    • de Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT (1992) The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255: 989-991
    • (1992) Science , vol.255 , pp. 989-991
    • De Vries, C.1    Escobedo, J.A.2    Ueno, H.3    Houck, K.4    Ferrara, N.5    Williams, L.T.6
  • 60
    • 0001288041 scopus 로고
    • Biology of primate retroviruses
    • Klein G (ed) Raven Press, New York
    • Deinhardt F (1980) Biology of primate retroviruses. In: Klein G (ed) Viral oncology. Raven Press, New York, pp 357-398
    • (1980) Viral Oncology , pp. 357-398
    • Deinhardt, F.1
  • 61
    • 0024355092 scopus 로고
    • Autocrine interaction between TGFalpha and EGF-receptor: Quantitative requirements for induction of the malignant phenotype
    • Di Marco E, Pierce JH, Fleming TP, Kraus MH, Molloy CJ, Aaronson SA, Di Fiore PP (1989) Autocrine interaction between TGFalpha and EGF-receptor: quantitative requirements for induction of the malignant phenotype. Oncogene 4: 831-838
    • (1989) Oncogene , vol.4 , pp. 831-838
    • Di Marco, E.1    Pierce, J.H.2    Fleming, T.P.3    Kraus, M.H.4    Molloy, C.J.5    Aaronson, S.A.6    Di Fiore, P.P.7
  • 62
    • 0028885029 scopus 로고
    • Distribution of epidermal growth factor receptor gene amplification in brain tumours and correlation to prognosis
    • Diedrich U, Lucius J, Baron E, Behnke J, Pabst B, Zoll B (1995) Distribution of epidermal growth factor receptor gene amplification in brain tumours and correlation to prognosis. J Neurol 242: 683-688
    • (1995) J Neurol , vol.242 , pp. 683-688
    • Diedrich, U.1    Lucius, J.2    Baron, E.3    Behnke, J.4    Pabst, B.5    Zoll, B.6
  • 64
    • 0026012807 scopus 로고
    • Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I
    • Drago J, Murphy M, Carroll SM, Harvey RP, Bartlett PF (1991) Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I. Proc Natl Acad Sci USA 88: 2199-2203
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2199-2203
    • Drago, J.1    Murphy, M.2    Carroll, S.M.3    Harvey, R.P.4    Bartlett, P.F.5
  • 65
    • 0025953395 scopus 로고
    • Distribution of vascular permeability factor (vascular endothelial growth factor) in tumours: Concentration in tumour blood vessels
    • Dvorak HF, Sioussat TM, Brown LF, Berse B, Nagy JA, Sotrel A, Manseau EJ et al (1991) Distribution of vascular permeability factor (vascular endothelial growth factor) in tumours: concentration in tumour blood vessels. J Exp Med 174: 1275-1278
    • (1991) J Exp Med , vol.174 , pp. 1275-1278
    • Dvorak, H.F.1    Sioussat, T.M.2    Brown, L.F.3    Berse, B.4    Nagy, J.A.5    Sotrel, A.6    Manseau, E.J.7
  • 66
    • 0021948135 scopus 로고
    • Fibroblasl growth factor is a mitogen for oligodendrocytes in vitro
    • Eccleston PA, Silberberg DH (1985) Fibroblasl growth factor is a mitogen for oligodendrocytes in vitro. Brain Res 353: 315-318
    • (1985) Brain Res , vol.353 , pp. 315-318
    • Eccleston, P.A.1    Silberberg, D.H.2
  • 67
    • 0032539616 scopus 로고    scopus 로고
    • Activity-dependent regulation of neu differentiation factor/neuregulin expression in rat brain
    • Eilam R, Pinkas-Kramarski R, Ratzkin BJ, Segal M, Yarden Y (1998) Activity-dependent regulation of Neu differentiation factor/neuregulin expression in rat brain. Proc Natl Acad Sci USA 95: 1888-1893
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1888-1893
    • Eilam, R.1    Pinkas-Kramarski, R.2    Ratzkin, B.J.3    Segal, M.4    Yarden, Y.5
  • 68
    • 0025790916 scopus 로고
    • Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo
    • Ekstrand AJ, James CD, Cavenee WK, Seliger B, Pettersson RF, Collins VP (1991) Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res 51: 2164-2172
    • (1991) Cancer Res , vol.51 , pp. 2164-2172
    • Ekstrand, A.J.1    James, C.D.2    Cavenee, W.K.3    Seliger, B.4    Pettersson, R.F.5    Collins, V.P.6
  • 69
    • 0028927012 scopus 로고
    • Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor
    • Ekstrand AJ, Liu L, He J, Hamid ML, Longo N, Collins VP, James CD (1995) Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor. Oncogene 10: 1455-1460
    • (1995) Oncogene , vol.10 , pp. 1455-1460
    • Ekstrand, A.J.1    Liu, L.2    He, J.3    Hamid, M.L.4    Longo, N.5    Collins, V.P.6    James, C.D.7
  • 70
    • 0028237507 scopus 로고
    • Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification
    • Ekstrand AJ, Longo N, Hamid ML, Olson JJ, Liu L, Collins VP, James CD (1994) Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification. Oncogene 9: 2313-2320
    • (1994) Oncogene , vol.9 , pp. 2313-2320
    • Ekstrand, A.J.1    Longo, N.2    Hamid, M.L.3    Olson, J.J.4    Liu, L.5    Collins, V.P.6    James, C.D.7
  • 71
    • 0026521394 scopus 로고
    • Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails
    • Ekstrand AJ, Sugawa N, James CD, Collins VP (1992) Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails. Proc Natl Acad Sci USA 89: 4309-4313
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4309-4313
    • Ekstrand, A.J.1    Sugawa, N.2    James, C.D.3    Collins, V.P.4
  • 72
    • 0031470359 scopus 로고    scopus 로고
    • Cell scattering and migration induced by autocrine transforming growth factor alpha in human glioma cells in vitro
    • El-Obeid A, Bongcam-Rudloff E, Sorby M, Ostman A, Nister M, Westermark B (1997) Cell scattering and migration induced by autocrine transforming growth factor alpha in human glioma cells in vitro. Cancer Res 57: 5598-5604
    • (1997) Cancer Res , vol.57 , pp. 5598-5604
    • El-Obeid, A.1    Bongcam-Rudloff, E.2    Sorby, M.3    Ostman, A.4    Nister, M.5    Westermark, B.6
  • 73
    • 17044450254 scopus 로고    scopus 로고
    • Induction of apoptosis in rat hepatocarcinoma cells by expression of IGF-I antisense c-DNA
    • G.A.
    • Ellouk-Achard S, Djenabi S, De O, G.A., Desauty G, Duc H, Zohair M, Trojan J et al (1998) Induction of apoptosis in rat hepatocarcinoma cells by expression of IGF-I antisense c-DNA. J Hepatol 29: 807-818
    • (1998) J Hepatol , vol.29 , pp. 807-818
    • Ellouk-Achard, S.1    Djenabi, S.2    De, O.3    Desauty, G.4    Duc, H.5    Zohair, M.6    Trojan, J.7
  • 74
    • 0027530832 scopus 로고
    • Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro
    • Engebraaten O, Bjerkvig R, Pedersen PH, Laerum OD (1993) Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro. Int J Cancer 53: 209-214
    • (1993) Int J Cancer , vol.53 , pp. 209-214
    • Engebraaten, O.1    Bjerkvig, R.2    Pedersen, P.H.3    Laerum, O.D.4
  • 76
    • 0029865486 scopus 로고    scopus 로고
    • Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy
    • Fakhrai H, Dorigo O, Shawler DL, Lin H, Mercola D, Black KL, Royston I et al (1996) Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy. Proc Natl Acad Sci USA 93: 2909-2914
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2909-2914
    • Fakhrai, H.1    Dorigo, O.2    Shawler, D.L.3    Lin, H.4    Mercola, D.5    Black, K.L.6    Royston, I.7
  • 77
    • 0027526321 scopus 로고
    • ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family
    • Falls DL, Rosen KM, Corfas G, Lane WS, Fischbach GD (1993) ARIA, a protein that stimulates acetylcholine receptor synthesis, is a member of the neu ligand family. Cell 72: 801-815
    • (1993) Cell , vol.72 , pp. 801-815
    • Falls, D.L.1    Rosen, K.M.2    Corfas, G.3    Lane, W.S.4    Fischbach, G.D.5
  • 79
    • 0030771026 scopus 로고    scopus 로고
    • Signal transduction pathways and their relevance in human astrocytomas
    • Feldkamp MM, Lau N, Guha A (1997) Signal transduction pathways and their relevance in human astrocytomas. J Neurooncol 35: 223-248
    • (1997) J Neurooncol , vol.35 , pp. 223-248
    • Feldkamp, M.M.1    Lau, N.2    Guha, A.3
  • 80
    • 0030500444 scopus 로고    scopus 로고
    • Vascular endothelial growth factor
    • Ferrara N (1996) Vascular endothelial growth factor. Eur J Cancer 32A: 2413-2422
    • (1996) Eur J Cancer , vol.32 A , pp. 2413-2422
    • Ferrara, N.1
  • 81
    • 0031039243 scopus 로고    scopus 로고
    • The biology of vascular endothelial growth factor
    • Ferrara N, Davis-Smyth T (1997) The biology of vascular endothelial growth factor. Endocr Rev 18: 4-25
    • (1997) Endocr Rev , vol.18 , pp. 4-25
    • Ferrara, N.1    Davis-Smyth, T.2
  • 82
    • 0028840752 scopus 로고
    • Antiproliferative and angiostatic activity of suramin analogues
    • Firsching A, Nickel P, Mora P, Allolio B (1995) Antiproliferative and angiostatic activity of suramin analogues. Cancer Research 55: 4957-4961
    • (1995) Cancer Research , vol.55 , pp. 4957-4961
    • Firsching, A.1    Nickel, P.2    Mora, P.3    Allolio, B.4
  • 83
    • 0032504049 scopus 로고    scopus 로고
    • Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4
    • Fitzpatrick VD, Pisacane PI, Vandlen RL, Sliwkowski MX (1998) Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4. FEBS Lett 431: 102-106
    • (1998) FEBS Lett , vol.431 , pp. 102-106
    • Fitzpatrick, V.D.1    Pisacane, P.I.2    Vandlen, R.L.3    Sliwkowski, M.X.4
  • 84
    • 0026649809 scopus 로고
    • Demonstration of an activated platelet-derived growth factor autocrine pathway and its role in human tumour cell proliferation in vitro
    • Fleming TP, Matsui T, Heidaran MA, Molloy CJ, Artrip J, Aaronson SA (1992) Demonstration of an activated platelet-derived growth factor autocrine pathway and its role in human tumour cell proliferation in vitro. Oncogene 7: 1355-1359
    • (1992) Oncogene , vol.7 , pp. 1355-1359
    • Fleming, T.P.1    Matsui, T.2    Heidaran, M.A.3    Molloy, C.J.4    Artrip, J.5    Aaronson, S.A.6
  • 85
    • 0040334645 scopus 로고
    • Autocrine mechanism for v-sis transformation requires cell surface localization of internally activated growth factor receptors
    • Fleming TP, Matsui T, Molloy CJ, Robbins KC, Aaronson SA (1989) Autocrine mechanism for v-sis transformation requires cell surface localization of internally activated growth factor receptors. Proc Natl Acad Sci USA 86: 8063-8067
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 8063-8067
    • Fleming, T.P.1    Matsui, T.2    Molloy, C.J.3    Robbins, K.C.4    Aaronson, S.A.5
  • 86
    • 0026793260 scopus 로고
    • Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumours
    • Fleming TP, Saxena A, Clark WC, Robertson JT, Oldfield EH, Aaronson SA, Ali IU (1992) Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumours. Cancer Res 52: 4550-4553
    • (1992) Cancer Res , vol.52 , pp. 4550-4553
    • Fleming, T.P.1    Saxena, A.2    Clark, W.C.3    Robertson, J.T.4    Oldfield, E.H.5    Aaronson, S.A.6    Ali, I.U.7
  • 87
    • 0025930443 scopus 로고
    • Expression of TGF-beta 2 in human glioblastoma: A role in resistance to immune rejection?
    • Fontana A, Bodmer S, Frei K, Malipiero U, Siepl C (1991) Expression of TGF-beta 2 in human glioblastoma: a role in resistance to immune rejection? Ciba Found Symp 157: 232-241
    • (1991) Ciba Found Symp , vol.157 , pp. 232-241
    • Fontana, A.1    Bodmer, S.2    Frei, K.3    Malipiero, U.4    Siepl, C.5
  • 89
    • 0029143960 scopus 로고
    • Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction
    • Friesel RE, Maciag T (1995) Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction. FASEB J 9: 919-925
    • (1995) FASEB J , vol.9 , pp. 919-925
    • Friesel, R.E.1    Maciag, T.2
  • 90
    • 0026799316 scopus 로고
    • Inhibition of angiogenesis by suramin
    • Gagliardi A, Hadd H, Collins DC (1992) Inhibition of angiogenesis by suramin. Cancer Res 52: 5073-5075
    • (1992) Cancer Res , vol.52 , pp. 5073-5075
    • Gagliardi, A.1    Hadd, H.2    Collins, D.C.3
  • 91
    • 0023854380 scopus 로고
    • Expression of two types of receptor for insulin-like growth factors in human malignant glioma
    • Gammeltoft S, Ballotti R, Kowalski A, Westermark B, Van Obberghen E (1988) Expression of two types of receptor for insulin-like growth factors in human malignant glioma. Cancer Res 48: 1233-1237
    • (1988) Cancer Res , vol.48 , pp. 1233-1237
    • Gammeltoft, S.1    Ballotti, R.2    Kowalski, A.3    Westermark, B.4    Van Obberghen, E.5
  • 92
    • 0029097155 scopus 로고
    • The potential role of basic fibroblast growth factor in the transformation of cultured primary human fetal astrocytes and the proliferation of human glioma (U-87) cells
    • Gately S, Soff GA, Brem S (1995) The potential role of basic fibroblast growth factor in the transformation of cultured primary human fetal astrocytes and the proliferation of human glioma (U-87) cells. Neurosurgery 37: 723-732
    • (1995) Neurosurgery , vol.37 , pp. 723-732
    • Gately, S.1    Soff, G.A.2    Brem, S.3
  • 93
    • 0028963971 scopus 로고
    • Cells transfecled with the basic fibroblast growth factor gene fused to a signal sequence are invasive in vitro and in situ in the brain
    • Gately S, Tsanaclis AM, Takano S, Klagsbrun M, Brem S (1995) Cells transfecled with the basic fibroblast growth factor gene fused to a signal sequence are invasive in vitro and in situ in the brain. Neurosurgery 36: 780-788
    • (1995) Neurosurgery , vol.36 , pp. 780-788
    • Gately, S.1    Tsanaclis, A.M.2    Takano, S.3    Klagsbrun, M.4    Brem, S.5
  • 95
    • 0030751493 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-I/KDR, is up-regulated by hypoxia
    • Gerber HP, Condorelli F, Park J, Ferrara N (1997) Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-I/KDR, is up-regulated by hypoxia. J Biol Chem 272: 23659-23667
    • (1997) J Biol Chem , vol.272 , pp. 23659-23667
    • Gerber, H.P.1    Condorelli, F.2    Park, J.3    Ferrara, N.4
  • 97
    • 0008222162 scopus 로고
    • Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement
    • Gherardi E, Gray J, Stoker M, Perryman M, Furlong R (1989) Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement. Proc Natl Acad Sci USA 86: 5844-5848
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5844-5848
    • Gherardi, E.1    Gray, J.2    Stoker, M.3    Perryman, M.4    Furlong, R.5
  • 98
    • 0024379685 scopus 로고
    • Insulin and insulin-like growth factor I in brain tumours: Binding and in vitro effects
    • Glick RP, Gettleman R, Patel K, Lakshman R, Tsibris JC (1989) Insulin and insulin-like growth factor I in brain tumours: binding and in vitro effects. Neurosurgery 24: 791-797
    • (1989) Neurosurgery , vol.24 , pp. 791-797
    • Glick, R.P.1    Gettleman, R.2    Patel, K.3    Lakshman, R.4    Tsibris, J.C.5
  • 99
    • 0030772251 scopus 로고    scopus 로고
    • Insulin-like growth factors in central nervous system tumours
    • Glick RP, Lichtor T, Unterman TG (1997) Insulin-like growth factors in central nervous system tumours. J Neurooncol 35: 315-325
    • (1997) J Neurooncol , vol.35 , pp. 315-325
    • Glick, R.P.1    Lichtor, T.2    Unterman, T.G.3
  • 100
    • 0026707401 scopus 로고
    • Insulin and insulin-like growth factors in central nervous system tumours. Part V: Production of insulin-like growth factors I and II in vitro
    • Glick RP, Unterman TG, Van der Woude M, Blaydes LZ (1992) Insulin and insulin-like growth factors in central nervous system tumours. Part V: Production of insulin-like growth factors I and II in vitro. J Neurosurg 77: 445-450
    • (1992) J Neurosurg , vol.77 , pp. 445-450
    • Glick, R.P.1    Unterman, T.G.2    Van Der Woude, M.3    Blaydes, L.Z.4
  • 101
    • 0028095127 scopus 로고
    • Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin
    • Goldberg MA, Schneider TJ (1994) Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin. J Biol Chem 269: 4355-4359
    • (1994) J Biol Chem , vol.269 , pp. 4355-4359
    • Goldberg, M.A.1    Schneider, T.J.2
  • 102
    • 0027412319 scopus 로고
    • Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: A model of glioblastoma multiforme pathophysiology
    • Goldman CK, Kim J, Wong W-L, King V, Brock T, Gillespie GY (1993) Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology. Mol Biol Cell 4: 121-133
    • (1993) Mol Biol Cell , vol.4 , pp. 121-133
    • Goldman, C.K.1    Kim, J.2    Wong, W.-L.3    King, V.4    Brock, T.5    Gillespie, G.Y.6
  • 103
    • 0025690737 scopus 로고
    • Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: A mechanism for receptor trans-regulation
    • Goldman R, Levy RB, Peles E, Yarden Y (1990) Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor trans-regulation. Biochemistry 29: 11024-11028
    • (1990) Biochemistry , vol.29 , pp. 11024-11028
    • Goldman, R.1    Levy, R.B.2    Peles, E.3    Yarden, Y.4
  • 105
    • 0345567274 scopus 로고
    • Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: Evidence for more than one receptor class
    • Gronwald RG, Grant FJ, Haldeman BA, Hart CE, O'Hara PJ, Hagen FS, Ross R et al (1988) Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class. Proc Natl Acad Sci USA 85: 3435-3439
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 3435-3439
    • Gronwald, R.G.1    Grant, F.J.2    Haldeman, B.A.3    Hart, C.E.4    O'Hara, P.J.5    Hagen, F.S.6    Ross, R.7
  • 106
    • 0028911678 scopus 로고
    • Expression of pdgf and pdgf receptors in human astrocytoma operation specimens supports the existence of an autocrine loop
    • Guha A, Dashner K, Black PM, Wagner JA, Stiles CD (1995) Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop. Int J Cancer 60: 168-173
    • (1995) Int J Cancer , vol.60 , pp. 168-173
    • Guha, A.1    Dashner, K.2    Black, P.M.3    Wagner, J.A.4    Stiles, C.D.5
  • 107
    • 0031465906 scopus 로고    scopus 로고
    • Proliferation of human malignant astrocytomas is dependent on Ras activation
    • Guha A, Feldkamp MM, Lau N, Boss G, Pawson A (1997) Proliferation of human malignant astrocytomas is dependent on Ras activation. Oncogene 15: 2755-2765
    • (1997) Oncogene , vol.15 , pp. 2755-2765
    • Guha, A.1    Feldkamp, M.M.2    Lau, N.3    Boss, G.4    Pawson, A.5
  • 109
    • 0030728619 scopus 로고    scopus 로고
    • The road less travelled: C-kit and stem cell factor
    • Hamel W, Westphal M (1997) The road less travelled: c-kit and stem cell factor. J Neurooncol 35: 327-333
    • (1997) J Neurooncol , vol.35 , pp. 327-333
    • Hamel, W.1    Westphal, M.2
  • 110
    • 0008918557 scopus 로고
    • Proto-oncogene expression in human glioma derived cell lines
    • Hamel W, Westphal M, Shepard HM (1992) Proto-oncogene expression in human glioma derived cell lines. Int J Oncol 1: 673-682
    • (1992) Int J Oncol , vol.1 , pp. 673-682
    • Hamel, W.1    Westphal, M.2    Shepard, H.M.3
  • 111
  • 112
    • 0023738922 scopus 로고
    • A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain
    • Hammacher A, Hellman U, Johnsson A, Ostman A, Gunnarsson K, Westermark B, Wasteson A et al (1988) A major part of platelet-derived growth factor purified from human platelets is a heterodimer of one A and one B chain. J Biol Chem 263: 16493-16498
    • (1988) J Biol Chem , vol.263 , pp. 16493-16498
    • Hammacher, A.1    Hellman, U.2    Johnsson, A.3    Ostman, A.4    Gunnarsson, K.5    Westermark, B.6    Wasteson, A.7
  • 113
    • 0023678478 scopus 로고
    • A human glioma cell line secretes three structurally and functionally different dimeric forms of platelet-derived growth factor
    • Hammacher A, Nister M, Westermark B, Heldin CH (1988) A human glioma cell line secretes three structurally and functionally different dimeric forms of platelet-derived growth factor. Eur J Biochem 176: 179-186
    • (1988) Eur J Biochem , vol.176 , pp. 179-186
    • Hammacher, A.1    Nister, M.2    Westermark, B.3    Heldin, C.H.4
  • 114
    • 0025220468 scopus 로고
    • Platelet derived growth factor (PDGF) autocrine components in human tumour cell lines
    • Harsh GR, Keating MT, Escobedo JA, Williams LT (1990) Platelet derived growth factor (PDGF) autocrine components in human tumour cell lines. J Neurooncol 8: 1-12
    • (1990) J Neurooncol , vol.8 , pp. 1-12
    • Harsh, G.R.1    Keating, M.T.2    Escobedo, J.A.3    Williams, L.T.4
  • 116
    • 0030797470 scopus 로고    scopus 로고
    • Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme
    • Hayashi Y, Ueki K, Waha A, Wiestler OD, Louis DN, von Deimling A (1997) Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme. Brain Pathol 7: 871-875
    • (1997) Brain Pathol , vol.7 , pp. 871-875
    • Hayashi, Y.1    Ueki, K.2    Waha, A.3    Wiestler, O.D.4    Louis, D.N.5    Von Deimling, A.6
  • 117
    • 0026555125 scopus 로고
    • Expression of the neu oncogene under the transcriptional control of the myelin basic protein gene in transgenic mice: Generation of transformed glial cells
    • Hayes C, Kelly D, Murayama S, Komiyama A, Suzuki K, Popko B (1992) Expression of the neu oncogene under the transcriptional control of the myelin basic protein gene in transgenic mice: generation of transformed glial cells. J Neurosci Res 31: 175-187
    • (1992) J Neurosci Res , vol.31 , pp. 175-187
    • Hayes, C.1    Kelly, D.2    Murayama, S.3    Komiyama, A.4    Suzuki, K.5    Popko, B.6
  • 118
    • 0028838012 scopus 로고
    • Dimerization of cell surface receptors in signal transduction
    • Heldin CH (1995) Dimerization of cell surface receptors in signal transduction. Cell 80: 213-223
    • (1995) Cell , vol.80 , pp. 213-223
    • Heldin, C.H.1
  • 119
    • 0024007666 scopus 로고
    • Binding of different dimeric forms of PDGF to human fibroblasts: Evidence for two separate receptor types
    • Heldin CH, Backstrom G, Ostman A, Hammacher A, Ronnstrand L, Rubin K, Nister M et al (1988) Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types. EMBO J 7: 1387-1393
    • (1988) EMBO J , vol.7 , pp. 1387-1393
    • Heldin, C.H.1    Backstrom, G.2    Ostman, A.3    Hammacher, A.4    Ronnstrand, L.5    Rubin, K.6    Nister, M.7
  • 120
    • 0032547385 scopus 로고    scopus 로고
    • Signal transduction via platelet-derived growth factor receptors
    • Heldin CH, Ostman A, Ronnstrand L (1998) Signal transduction via platelet-derived growth factor receptors. Biochim Biophys Acta 1378: F79-113
    • (1998) Biochim Biophys Acta , vol.1378
    • Heldin, C.H.1    Ostman, A.2    Ronnstrand, L.3
  • 121
    • 0026772431 scopus 로고
    • Platelet-derived growth factor and its receptors in human glioma tissue: Expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops
    • Hermanson M, Funa K, Hartman M, Claesson-Welsh L, Heldin CH, Westermark B, Nister M (1992) Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops. Cancer Res 52: 3213-3219
    • (1992) Cancer Res , vol.52 , pp. 3213-3219
    • Hermanson, M.1    Funa, K.2    Hartman, M.3    Claesson-Welsh, L.4    Heldin, C.H.5    Westermark, B.6    Nister, M.7
  • 122
    • 9044248587 scopus 로고    scopus 로고
    • Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas
    • Hermanson M, Funa K, Koopmann J, Maintz D, Waha A, Westermark B, Heldin CH et al (1996) Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas. Cancer Res 56: 164-171
    • (1996) Cancer Res , vol.56 , pp. 164-171
    • Hermanson, M.1    Funa, K.2    Koopmann, J.3    Maintz, D.4    Waha, A.5    Westermark, B.6    Heldin, C.H.7
  • 123
    • 0008887031 scopus 로고
    • Endothelial cell hyperplasia in human glioblastoma: Coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation
    • Hermansson M, Nister M, Betsholtz C, Heldin CH, Westermark B, Funa K (1988) Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation. Proc Natl Acad Sci USA 85: 7748-7752
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7748-7752
    • Hermansson, M.1    Nister, M.2    Betsholtz, C.3    Heldin, C.H.4    Westermark, B.5    Funa, K.6
  • 124
    • 0027489847 scopus 로고
    • Prognostic relevance of epidermal growth factor receptor (EGF-R) and c-neu/erbB2 expression in glioblastomas (GBMs)
    • Hiesiger EM, Hayes RL, Pierz DM, Budzilovich GN (1993) Prognostic relevance of epidermal growth factor receptor (EGF-R) and c-neu/erbB2 expression in glioblastomas (GBMs). J Neurooncol 16: 93-104
    • (1993) J Neurooncol , vol.16 , pp. 93-104
    • Hiesiger, E.M.1    Hayes, R.L.2    Pierz, D.M.3    Budzilovich, G.N.4
  • 125
    • 0029015913 scopus 로고
    • Coexpression of the c-kit and stem cell factor genes in breast carcinoma
    • Hines SJ, Organ C, Kornstein MJ, Krystal GW (1995) Coexpression of the c-kit and stem cell factor genes in breast carcinoma. Cell Growth Diff 6: 769-779
    • (1995) Cell Growth Diff , vol.6 , pp. 769-779
    • Hines, S.J.1    Organ, C.2    Kornstein, M.J.3    Krystal, G.W.4
  • 127
    • 0029040445 scopus 로고
    • Sensory and motor neuron-derived factor. A novel heregulin variant highly expressed in sensory and motor neurons
    • Ho WH, Armanini MP, Nuijens A, Phillips HS, Osheroff PL (1995) Sensory and motor neuron-derived factor. A novel heregulin variant highly expressed in sensory and motor neurons. J Biol Chem 270: 14523-14532
    • (1995) J Biol Chem , vol.270 , pp. 14523-14532
    • Ho, W.H.1    Armanini, M.P.2    Nuijens, A.3    Phillips, H.S.4    Osheroff, P.L.5
  • 130
    • 0032101640 scopus 로고    scopus 로고
    • Inhibition of tumourigenesis and induction of apoptosis in human tumour cells by the stable expression of a myristylated COOH terminus of the insulin-like growth factor I receptor
    • Hongo A, Yumet G, Resnicoff M, Romano G, O'Connor R, Baserga R (1998) Inhibition of tumourigenesis and induction of apoptosis in human tumour cells by the stable expression of a myristylated COOH terminus of the insulin-like growth factor I receptor. Cancer Res 58: 2477-2484
    • (1998) Cancer Res , vol.58 , pp. 2477-2484
    • Hongo, A.1    Yumet, G.2    Resnicoff, M.3    Romano, G.4    O'Connor, R.5    Baserga, R.6
  • 131
    • 14444288522 scopus 로고    scopus 로고
    • The enhanced tumourigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling
    • Huang HS, Nagane M, Klingbeil CK, Lin H, Nishikawa R, Ji XD, Huang CM et al (1997) The enhanced tumourigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. J Biol Chem 272: 2927-2935
    • (1997) J Biol Chem , vol.272 , pp. 2927-2935
    • Huang, H.S.1    Nagane, M.2    Klingbeil, C.K.3    Lin, H.4    Nishikawa, R.5    Ji, X.D.6    Huang, C.M.7
  • 133
    • 0026570136 scopus 로고
    • Amplification of epidermal growth factor receptor gene in gliomas: Histopathology and prognosis
    • Hurtt MR, Moossy J, Donovan-Peluso M, Locker J (1992) Amplification of epidermal growth factor receptor gene in gliomas: histopathology and prognosis. J Neuropathol Exp Neurol 51: 84-90
    • (1992) J Neuropathol Exp Neurol , vol.51 , pp. 84-90
    • Hurtt, M.R.1    Moossy, J.2    Donovan-Peluso, M.3    Locker, J.4
  • 134
    • 0028670125 scopus 로고
    • The biology of erbB-2/neu/HER-2 and its role in cancer
    • Hynes NE, Stern DF (1994) The biology of erbB-2/neu/HER-2 and its role in cancer. Biochim Biophys Acta 1198: 165-184
    • (1994) Biochim Biophys Acta , vol.1198 , pp. 165-184
    • Hynes, N.E.1    Stern, D.F.2
  • 135
    • 0029117223 scopus 로고
    • Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
    • Ikeda E, Achen MG, Breier G, Risau W (1995) Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem 270: 19761-19766
    • (1995) J Biol Chem , vol.270 , pp. 19761-19766
    • Ikeda, E.1    Achen, M.G.2    Breier, G.3    Risau, W.4
  • 136
    • 0030021142 scopus 로고    scopus 로고
    • Transforming growth factor-beta-mediated autocrine growth regulation of gliomas as detected with phosphorothionate antisense oligonucleotides
    • Jachimczak P, Hessdorfer B, Fabel-Schulte K, Wismeth C, Brysch W, Schlingensiepen KH, Bauer A et al (1996) Transforming growth factor-beta-mediated autocrine growth regulation of gliomas as detected with phosphorothionate antisense oligonucleotides. Int J Cancer 65: 332-337
    • (1996) Int J Cancer , vol.65 , pp. 332-337
    • Jachimczak, P.1    Hessdorfer, B.2    Fabel-Schulte, K.3    Wismeth, C.4    Brysch, W.5    Schlingensiepen, K.H.6    Bauer, A.7
  • 137
    • 0029812091 scopus 로고    scopus 로고
    • Intracellular expression of a single-chain antibody directed to the EGFR leads to growth inhibition of tumour cells
    • Jannot CB, Beerli RR, Mason S, Gullick WJ, Hynes NE (1996) Intracellular expression of a single-chain antibody directed to the EGFR leads to growth inhibition of tumour cells. Oncogene 13: 275-282
    • (1996) Oncogene , vol.13 , pp. 275-282
    • Jannot, C.B.1    Beerli, R.R.2    Mason, S.3    Gullick, W.J.4    Hynes, N.E.5
  • 138
    • 0026719118 scopus 로고
    • Prognostic implications of p53 protein, epidermal growth factor receptor, and Ki-67 labelling in brain tumours
    • Jaros E, Perry RH, Adam L, Kelly PJ, Crawford PJ, Kalbag RM, Mendelow AD et al (1992) Prognostic implications of p53 protein, epidermal growth factor receptor, and Ki-67 labelling in brain tumours. Br J Cancer 66: 373-385
    • (1992) Br J Cancer , vol.66 , pp. 373-385
    • Jaros, E.1    Perry, R.H.2    Adam, L.3    Kelly, P.J.4    Crawford, P.J.5    Kalbag, R.M.6    Mendelow, A.D.7
  • 139
    • 0030039519 scopus 로고    scopus 로고
    • Enhanced tumourigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network
    • Jeffers M, Rong S, Vande-Woude GF (1996) Enhanced tumourigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network. Mol Cell Biol 16: 1115-1125
    • (1996) Mol Cell Biol , vol.16 , pp. 1115-1125
    • Jeffers, M.1    Rong, S.2    Vande-Woude, G.F.3
  • 140
    • 0028895952 scopus 로고
    • Neuregulins are concentrated at nerve-muscle synapses and activate ACh-receptor gene expression
    • Jo SA, Zhu X, Marchionni MA, Burden SJ (1995) Neuregulins are concentrated at nerve-muscle synapses and activate ACh-receptor gene expression. Nature 373: 158-161
    • (1995) Nature , vol.373 , pp. 158-161
    • Jo, S.A.1    Zhu, X.2    Marchionni, M.A.3    Burden, S.J.4
  • 141
    • 0028308229 scopus 로고
    • Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain
    • Jung W, Castren E, Odenthal M, Vande Woude GF, Ishii T, Dienes HP, Lindholm D et al (1994) Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain. J Cell. Biol. 126: 485-494
    • (1994) J Cell. Biol. , vol.126 , pp. 485-494
    • Jung, W.1    Castren, E.2    Odenthal, M.3    Vande Woude, G.F.4    Ishii, T.5    Dienes, H.P.6    Lindholm, D.7
  • 142
    • 0023784452 scopus 로고
    • Identification of an insulin-like factor in astrocyte conditioned medium
    • Kadle R, Suksang C, Roberson ED, Fellows RE (1988) Identification of an insulin-like factor in astrocyte conditioned medium. Brain Res 460: 60-67
    • (1988) Brain Res , vol.460 , pp. 60-67
    • Kadle, R.1    Suksang, C.2    Roberson, E.D.3    Fellows, R.E.4
  • 143
    • 0025189619 scopus 로고
    • Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation
    • Kaleko M, Rutter WJ, Miller AD (1990) Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation. Mol Cell Biol 10: 464-473
    • (1990) Mol Cell Biol , vol.10 , pp. 464-473
    • Kaleko, M.1    Rutter, W.J.2    Miller, A.D.3
  • 145
  • 146
    • 0023848656 scopus 로고
    • Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells
    • Keating MT, Williams LT (1988) Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cells. Science 239: 914-916
    • (1988) Science , vol.239 , pp. 914-916
    • Keating, M.T.1    Williams, L.T.2
  • 148
    • 0027958348 scopus 로고
    • Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor/vascular permeability factor in brain tumour tissue and cyst fluid
    • Kieser A, Weich HA, Brandner G, Marme D, Kolch W (1994) Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor/vascular permeability factor in brain tumour tissue and cyst fluid. Oncogene 9: 963-969
    • (1994) Oncogene , vol.9 , pp. 963-969
    • Kieser, A.1    Weich, H.A.2    Brandner, G.3    Marme, D.4    Kolch, W.5
  • 149
    • 0024504878 scopus 로고
    • Rat C6 glial cells synthesize insulin-like growth factor I (IGF-I) and express IGF-I receptors and IGF-II/mannose 6-phosphate receptors
    • Kiess W, Lee L, Graham DE, Greenstein L, Tseng LY, Rechler MM, Nissley SP (1989) Rat C6 glial cells synthesize insulin-like growth factor I (IGF-I) and express IGF-I receptors and IGF-II/mannose 6-phosphate receptors. Endocrinology 124: 1727-1736
    • (1989) Endocrinology , vol.124 , pp. 1727-1736
    • Kiess, W.1    Lee, L.2    Graham, D.E.3    Greenstein, L.4    Tseng, L.Y.5    Rechler, M.M.6    Nissley, S.P.7
  • 150
    • 0024023873 scopus 로고
    • Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumour cell line SK-BR-3
    • King CR, Borrello I, Bellot F, Comoglio P, Schlessinger J (1988) Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumour cell line SK-BR-3. EMBO J 7: 1647-1651
    • (1988) EMBO J , vol.7 , pp. 1647-1651
    • King, C.R.1    Borrello, I.2    Bellot, F.3    Comoglio, P.4    Schlessinger, J.5
  • 153
    • 0000180377 scopus 로고    scopus 로고
    • Genetics of glioma progression and the definition of primary and secondary glioblastomas
    • Kleihues P, Ohgahki H (1997) Genetics of Glioma Progression and the Definition of primary and secondary glioblastomas. Brain Pathololgy 7: 1131-1136
    • (1997) Brain Pathololgy , vol.7 , pp. 1131-1136
    • Kleihues, P.1    Ohgahki, H.2
  • 154
    • 0024395587 scopus 로고
    • Synergistic interaction of p185c-neu and the egf receptor leads to transformation of rodent fibroblasts
    • Kokai Y, Myers JN, Wada T, Brown VI, LeVea CM, Davis JG, Dobashi K et al (1989) Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts. Cell 58: 287-292
    • (1989) Cell , vol.58 , pp. 287-292
    • Kokai, Y.1    Myers, J.N.2    Wada, T.3    Brown, V.I.4    LeVea, C.M.5    Davis, J.G.6    Dobashi, K.7
  • 156
    • 0028902256 scopus 로고
    • Extracellular matrix proteins inhibit proliferation, upregulate migration and induce morphological changes in human glioma cell lines
    • Koochekpour S, Merzak A, Pilkington GJ (1995) Extracellular matrix proteins inhibit proliferation, upregulate migration and induce morphological changes in human glioma cell lines. Eur J Cancer 31: 375-380
    • (1995) Eur J Cancer , vol.31 , pp. 375-380
    • Koochekpour, S.1    Merzak, A.2    Pilkington, G.J.3
  • 157
    • 0024326947 scopus 로고
    • Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumours
    • Kraus MH, Issing W, Miki T, Popescu NC, Aaronson SA (1989) Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumours. Proc Natl Acad Sci USA 86: 9193-9197
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9193-9197
    • Kraus, M.H.1    Issing, W.2    Miki, T.3    Popescu, N.C.4    Aaronson, S.A.5
  • 158
    • 0027254742 scopus 로고
    • Receptor tyrosine kinase expression in astrocytic lesions: Similar features in gliosis and glioma
    • Kristt DA, Reedy E, Yarden Y (1993) Receptor tyrosine kinase expression in astrocytic lesions: similar features in gliosis and glioma. Neurosurg 33: 106-115
    • (1993) Neurosurg , vol.33 , pp. 106-115
    • Kristt, D.A.1    Reedy, E.2    Yarden, Y.3
  • 159
    • 0026600613 scopus 로고
    • Amplification of alpha-platelet-derived growth factor receptor gene lacking an exon coding for a portion of the extracellular region in a primary brain tumour of glial origin
    • Kumabe T, Sohma Y, Kayama T, Yoshimoto T, Yamamoto T (1992) Amplification of alpha-platelet-derived growth factor receptor gene lacking an exon coding for a portion of the extracellular region in a primary brain tumour of glial origin. Oncogene 7: 627-633
    • (1992) Oncogene , vol.7 , pp. 627-633
    • Kumabe, T.1    Sohma, Y.2    Kayama, T.3    Yoshimoto, T.4    Yamamoto, T.5
  • 160
    • 0023696831 scopus 로고
    • The glioblastoma-derived T-cell suppressor factor/ transforming growth factor beta 2 inhibits the generation of lymphokine-activated killer (LAK) cells
    • Kuppner MC, Hamou MF, Bodmer S, Fontana A, de Tribolet N (1988) The glioblastoma-derived T-cell suppressor factor/ transforming growth factor beta 2 inhibits the generation of lymphokine-activated killer (LAK) cells. Int J Cancer 42: 562-567
    • (1988) Int J Cancer , vol.42 , pp. 562-567
    • Kuppner, M.C.1    Hamou, M.F.2    Bodmer, S.3    Fontana, A.4    De Tribolet, N.5
  • 162
    • 0025004547 scopus 로고
    • Antiproliferative effect of trapidil, a platelet-derived growth factor antagonist, on a glioma cell line in vitro
    • Kuratsu J, Ushio Y (1990) Antiproliferative effect of trapidil, a platelet-derived growth factor antagonist, on a glioma cell line in vitro. J Neurosurg 73: 436-440
    • (1990) J Neurosurg , vol.73 , pp. 436-440
    • Kuratsu, J.1    Ushio, Y.2
  • 163
    • 0031227543 scopus 로고    scopus 로고
    • Antisense insulin-like growth factor I transferred into a rat hepatoma cell line inhibits tumourigenesis by modulating major histocompatibility complex I cell surface expression
    • Lafarge-Frayssinet C, Duc HT, Frayssinet C, Sarasin A, Anthony D, Guo Y, Trojan J (1997) Antisense insulin-like growth factor I transferred into a rat hepatoma cell line inhibits tumourigenesis by modulating major histocompatibility complex I cell surface expression. Cancer Gene Ther 4: 276-285
    • (1997) Cancer Gene Ther , vol.4 , pp. 276-285
    • Lafarge-Frayssinet, C.1    Duc, H.T.2    Frayssinet, C.3    Sarasin, A.4    Anthony, D.5    Guo, Y.6    Trojan, J.7
  • 164
    • 0028102004 scopus 로고
    • Inhibition of tumour growth in liver epithelial cells transfected with a transforming growth factor alpha antisense gene
    • Laird AD, Brown PI, Fausto N (1994) Inhibition of tumour growth in liver epithelial cells transfected with a transforming growth factor alpha antisense gene. Cancer Res 54: 4224-4232
    • (1994) Cancer Res , vol.54 , pp. 4224-4232
    • Laird, A.D.1    Brown, P.I.2    Fausto, N.3
  • 165
    • 15444355527 scopus 로고    scopus 로고
    • Scatter factor promotes motility of human glioma and neuromicrovascularendothelial cells
    • Lamszus K, Schmidt NO, Jin L, Laterra J, Zagzag D, Way D, Witte M et al (1998) Scatter factor promotes motility of human glioma and neuromicrovascularendothelial cells. Int J Cancer 75: 19-28
    • (1998) Int J Cancer , vol.75 , pp. 19-28
    • Lamszus, K.1    Schmidt, N.O.2    Jin, L.3    Laterra, J.4    Zagzag, D.5    Way, D.6    Witte, M.7
  • 166
    • 0028087884 scopus 로고
    • Pathways leading to glioblastoma multiforme: A molecular analysis of genetic alterations in 65 astrocytic tumours
    • Lang FF, Miller DC, Koslow M, Newcomb EW (1994) Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumours. J Neurosurg 81: 427-436
    • (1994) J Neurosurg , vol.81 , pp. 427-436
    • Lang, F.F.1    Miller, D.C.2    Koslow, M.3    Newcomb, E.W.4
  • 167
    • 0029383677 scopus 로고
    • Tumour targeting through fibroblast growth factor receptors
    • Lappi DA (1995) Tumour targeting through fibroblast growth factor receptors. Semin Cancer Biol 6: 279-288
    • (1995) Semin Cancer Biol , vol.6 , pp. 279-288
    • Lappi, D.A.1
  • 168
    • 0025367994 scopus 로고
    • Molecular localization of the transforming and secretory properties of PDGF A and PDGF B
    • LaRochelle WJ, Giese N, May-Siroff M, Robbins KC, Aaronson SA (1990) Molecular localization of the transforming and secretory properties of PDGF A and PDGF B. Science 248: 1541-1544
    • (1990) Science , vol.248 , pp. 1541-1544
    • LaRochelle, W.J.1    Giese, N.2    May-Siroff, M.3    Robbins, K.C.4    Aaronson, S.A.5
  • 169
    • 0030975492 scopus 로고    scopus 로고
    • Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo
    • Laterra J, Nam M, Rosen EM, Rao JS, Lamszus K, Goldberg ID, Johnston P (1997) Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo. Lab Invest 76: 565-577
    • (1997) Lab Invest , vol.76 , pp. 565-577
    • Laterra, J.1    Nam, M.2    Rosen, E.M.3    Rao, J.S.4    Lamszus, K.5    Goldberg, I.D.6    Johnston, P.7
  • 171
    • 0028104202 scopus 로고
    • Regulation of signal transduction and signal diversity by receptor oligomerization
    • Lemmon MA, Schlessinger J (1994) Regulation of signal transduction and signal diversity by receptor oligomerization. Trends Biochem Sci 19: 459-463
    • (1994) Trends Biochem Sci , vol.19 , pp. 459-463
    • Lemmon, M.A.1    Schlessinger, J.2
  • 172
    • 0020967137 scopus 로고
    • Insulin-like growth factor I (IGF I) stimulates DNA synthesis in fetal rat brain cell cultures
    • Lenoir D, Honegger P (1983) Insulin-like growth factor I (IGF I) stimulates DNA synthesis in fetal rat brain cell cultures. Brain Res 283: 205-213
    • (1983) Brain Res , vol.283 , pp. 205-213
    • Lenoir, D.1    Honegger, P.2
  • 173
    • 0022800693 scopus 로고
    • Expression of c-sis and platelet-derived growth factor in in vitro-transformed glioma cells from rat brain tissue transplacentally treated with ethylnitrosourea
    • Lens PF, Altena B, Nusse R (1986) Expression of c-sis and platelet-derived growth factor in in vitro-transformed glioma cells from rat brain tissue transplacentally treated with ethylnitrosourea. Mol Cell Biol 6: 3537-3540
    • (1986) Mol Cell Biol , vol.6 , pp. 3537-3540
    • Lens, P.F.1    Altena, B.2    Nusse, R.3
  • 174
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N (1989) Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246: 1306-1309
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 175
    • 0026066984 scopus 로고
    • A specific combination of substrates is involved in signal transduction by the kit-encoded receptor
    • Lev S, Givol D, Yarden Y (1991) A specific combination of substrates is involved in signal transduction by the kit-encoded receptor. EMBO J 10: 647-654
    • (1991) EMBO J , vol.10 , pp. 647-654
    • Lev, S.1    Givol, D.2    Yarden, Y.3
  • 177
    • 0029879442 scopus 로고    scopus 로고
    • Growth regulation of human breast and ovarian tumour cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness
    • Lewis GD, Lofgren JA, McMurtrey AE, Nuijens A, Fendly BM, Bauer KD, Sliwkowski MX (1996) Growth regulation of human breast and ovarian tumour cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness. Cancer Res 56: 1457-1465
    • (1996) Cancer Res , vol.56 , pp. 1457-1465
    • Lewis, G.D.1    Lofgren, J.A.2    McMurtrey, A.E.3    Nuijens, A.4    Fendly, B.M.5    Bauer, K.D.6    Sliwkowski, M.X.7
  • 178
    • 0029944229 scopus 로고    scopus 로고
    • Heregulin is rapidly translocated to the nucleus and its transport is correlated with c-myc induction in breast cancer cells
    • Li W, Park JW, Nuijens A, Sliwkowski MX, Keller GA (1996) Heregulin is rapidly translocated to the nucleus and its transport is correlated with c-myc induction in breast cancer cells. Oncogene 12: 2473-2477
    • (1996) Oncogene , vol.12 , pp. 2473-2477
    • Li, W.1    Park, J.W.2    Nuijens, A.3    Sliwkowski, M.X.4    Keller, G.A.5
  • 179
    • 0021932240 scopus 로고
    • Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
    • Libermann TA, Nusbaum HR, Razon N, Kris R, Lax I, Soreq H, Whittle N et al (1985) Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature 313: 144-147
    • (1985) Nature , vol.313 , pp. 144-147
    • Libermann, T.A.1    Nusbaum, H.R.2    Razon, N.3    Kris, R.4    Lax, I.5    Soreq, H.6    Whittle, N.7
  • 181
    • 0029857998 scopus 로고    scopus 로고
    • Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: Targeting with a single chain antibody variable domain isolated by phage display
    • Lorimer IA, Keppler-Hafkemeyer A, Beers RA, Pegram CN, Bigner DD, Pastan I (1996) Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: targeting with a single chain antibody variable domain isolated by phage display. Proc Natl Acad Sci USA 93: 14815-14820
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14815-14820
    • Lorimer, I.A.1    Keppler-Hafkemeyer, A.2    Beers, R.A.3    Pegram, C.N.4    Bigner, D.D.5    Pastan, I.6
  • 182
    • 0030910239 scopus 로고    scopus 로고
    • A molecular genetic model of astrocytoma histopathology
    • Louis DN (1997) A molecular genetic model of astrocytoma histopathology. Brain Pathol 7: 755-764
    • (1997) Brain Pathol , vol.7 , pp. 755-764
    • Louis, D.N.1
  • 183
    • 0029094065 scopus 로고
    • A tiger behind many doors: Multiple genetic pathways to malignant glioma
    • Louis DN, Gusella JF (1995) A tiger behind many doors: multiple genetic pathways to malignant glioma. Trends Genet 11: 412-415
    • (1995) Trends Genet , vol.11 , pp. 412-415
    • Louis, D.N.1    Gusella, J.F.2
  • 186
    • 0026576726 scopus 로고
    • Insulin-like growth factors and cancer
    • Macaulay VM (1992) Insulin-like growth factors and cancer. Br J Cancer 65: 311-3 20
    • (1992) Br J Cancer , vol.65 , pp. 311-320
    • Macaulay, V.M.1
  • 187
    • 0023904523 scopus 로고
    • Selective amplification of the cytoplasmic domain of the epidermal growth factor receptor gene in glioblastoma multiforme
    • Maiden LT, Novak U, Kaye AH, Burgess AW (1988) Selective amplification of the cytoplasmic domain of the epidermal growth factor receptor gene in glioblastoma multiforme. Cancer Res 48: 2711-2714
    • (1988) Cancer Res , vol.48 , pp. 2711-2714
    • Maiden, L.T.1    Novak, U.2    Kaye, A.H.3    Burgess, A.W.4
  • 189
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall CJ (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80: 179-185
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 190
    • 0027391997 scopus 로고
    • Expression of the c-kit protein in human solid tumours and in corresponding fetal and adult normal tissues
    • Matsuda R, Takahashi T, Nakamura S, Sekido Y, Nishida K, Seto M, Seito T et al (1993) Expression of the c-kit protein in human solid tumours and in corresponding fetal and adult normal tissues. Am J Pathol 142: 339-346
    • (1993) Am J Pathol , vol.142 , pp. 339-346
    • Matsuda, R.1    Takahashi, T.2    Nakamura, S.3    Sekido, Y.4    Nishida, K.5    Seto, M.6    Seito, T.7
  • 191
    • 0024513240 scopus 로고
    • Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes
    • Matsui T, Heidaran M, Miki T, Popescu N, La Rochelle W, Kraus M, Pierce J et al (1989) Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes. Science 243: 800-804
    • (1989) Science , vol.243 , pp. 800-804
    • Matsui, T.1    Heidaran, M.2    Miki, T.3    Popescu, N.4    La Rochelle, W.5    Kraus, M.6    Pierce, J.7
  • 193
    • 0025282206 scopus 로고
    • Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance
    • Maxwell M, Naber SP, Wolfe H, Galanopoulos T, Hedley-Whyte ET, Black PM, Antoniades HN (1990) Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance. J Clin Invest 86: 131-140
    • (1990) J Clin Invest , vol.86 , pp. 131-140
    • Maxwell, M.1    Naber, S.P.2    Wolfe, H.3    Galanopoulos, T.4    Hedley-Whyte, E.T.5    Black, P.M.6    Antoniades, H.N.7
  • 194
    • 0025127106 scopus 로고
    • Insulin-like growth factor (IGF) binding to human fibroblast and glioblastoma cells: The modulating effect of cell released IGF binding proteins (IGFBPs)
    • McCusker RH, Camacho-Hubner C, Bayne ML, Cascieri MA, Clemmons DR (1990) Insulin-like growth factor (IGF) binding to human fibroblast and glioblastoma cells: the modulating effect of cell released IGF binding proteins (IGFBPs). J Cell Physiol 144: 244-253
    • (1990) J Cell Physiol , vol.144 , pp. 244-253
    • McCusker, R.H.1    Camacho-Hubner, C.2    Bayne, M.L.3    Cascieri, M.A.4    Clemmons, D.R.5
  • 195
    • 0022462027 scopus 로고
    • Insulin-like growth factor I/somatomedin C: A potent inducer of oligodendrocyte development
    • McMorris FA, Smith TM, DeSalvo S, Furlanetto RW (1986) Insulin-like growth factor I/somatomedin C: a potent inducer of oligodendrocyte development. Proc Natl Acad Sci USA 83: 822-826
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 822-826
    • McMorris, F.A.1    Smith, T.M.2    DeSalvo, S.3    Furlanetto, R.W.4
  • 197
    • 0025359028 scopus 로고
    • Insulin-like growth factor-I receptors in human glial tumours
    • Merrill MJ, Edwards NA (1990) Insulin-like growth factor-I receptors in human glial tumours. J Clin Endocrinol Metab 71: 199-209
    • (1990) J Clin Endocrinol Metab , vol.71 , pp. 199-209
    • Merrill, M.J.1    Edwards, N.A.2
  • 198
    • 0028146508 scopus 로고
    • Control of human glioma cell growth, migration and invasion in vitro by transforming growth factor beta 1
    • Merzak A, McCrea S, Koocheckpour S, Pilkington GJ (1994) Control of human glioma cell growth, migration and invasion in vitro by transforming growth factor beta 1. Br J Cancer 70: 199-203
    • (1994) Br J Cancer , vol.70 , pp. 199-203
    • Merzak, A.1    McCrea, S.2    Koocheckpour, S.3    Pilkington, G.J.4
  • 199
    • 0028053233 scopus 로고
    • Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development
    • Meyer D, Birchmeier C (1994) Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development. Proc Natl Acad Sci USA 91: 1064-1068
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1064-1068
    • Meyer, D.1    Birchmeier, C.2
  • 200
    • 0028827104 scopus 로고
    • Multiple essential functions of neuregulin in development
    • Meyer D, Birchmeier C (1995) Multiple essential functions of neuregulin in development. Nature 378: 386-390
    • (1995) Nature , vol.378 , pp. 386-390
    • Meyer, D.1    Birchmeier, C.2
  • 202
    • 0028174337 scopus 로고
    • Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant
    • Millauer B, Shawver LK, Plate KH, Risau W, Ullrich A (1994) Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant. Nature 367: 576-579
    • (1994) Nature , vol.367 , pp. 576-579
    • Millauer, B.1    Shawver, L.K.2    Plate, K.H.3    Risau, W.4    Ullrich, A.5
  • 203
    • 0027466849 scopus 로고
    • High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
    • Millauer B, Wizigmann-Voos S, Schnurch H, Martinez R, Moller NP, Risau W, Ullrich A (1993) High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72: 835-846
    • (1993) Cell , vol.72 , pp. 835-846
    • Millauer, B.1    Wizigmann-Voos, S.2    Schnurch, H.3    Martinez, R.4    Moller, N.P.5    Risau, W.6    Ullrich, A.7
  • 204
    • 0028105848 scopus 로고
    • Hypoxia regulatory elements of the human vascular endothelial growth factor gene
    • Minchenko A, Salceda S, Bauer T, Caro J (1994) Hypoxia regulatory elements of the human vascular endothelial growth factor gene. Cell Mol Biol Res 40: 35-39
    • (1994) Cell Mol Biol Res , vol.40 , pp. 35-39
    • Minchenko, A.1    Salceda, S.2    Bauer, T.3    Caro, J.4
  • 205
    • 0029591402 scopus 로고
    • Differential modulation of mitogen-activated protein (MAP) kinase/extracellular signal-related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor
    • Montgomery RB, Moscatello DK, Wong AJ, Cooper JA, Stahl WL (1995) Differential modulation of mitogen-activated protein (MAP) kinase/extracellular signal-related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor. J Biol Chem 270: 30562-30566
    • (1995) J Biol Chem , vol.270 , pp. 30562-30566
    • Montgomery, R.B.1    Moscatello, D.K.2    Wong, A.J.3    Cooper, J.A.4    Stahl, W.L.5
  • 206
    • 0032504607 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells
    • Moriyama T, Kataoka H, Hamasuna R, Yokogami K, Uehara H, Kawano H, Goya T et al (1998) Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells. Biochem Biophys Res Commun 249: 73-77
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 73-77
    • Moriyama, T.1    Kataoka, H.2    Hamasuna, R.3    Yokogami, K.4    Uehara, H.5    Kawano, H.6    Goya, T.7
  • 207
    • 0029951336 scopus 로고    scopus 로고
    • Effects of hepatocyte growth factor (HGF) on human glioma cells in vitro: HGF acts as a motility factor in glioma cells
    • Moriyama T, Kataoka H, Seguchi K, Tsubouchi H, Koono M (1996) Effects of hepatocyte growth factor (HGF) on human glioma cells in vitro: HGF acts as a motility factor in glioma cells. Int J Cancer 66: 678-685
    • (1996) Int J Cancer , vol.66 , pp. 678-685
    • Moriyama, T.1    Kataoka, H.2    Seguchi, K.3    Tsubouchi, H.4    Koono, M.5
  • 208
    • 0029115405 scopus 로고
    • Concomitant expression of hepatocyte growth factor (HGF), HGF activator and c-met genes in human glioma cells in vitro
    • Moriyama T, Kataoka H, Tsubouchi H, Koono M (1995) Concomitant expression of hepatocyte growth factor (HGF), HGF activator and c-met genes in human glioma cells in vitro. FEBS Lett 372: 78-82
    • (1995) FEBS Lett , vol.372 , pp. 78-82
    • Moriyama, T.1    Kataoka, H.2    Tsubouchi, H.3    Koono, M.4
  • 209
    • 0028332782 scopus 로고
    • Fibroblast growth factor receptor gene expression and immunoreactivity are elevated in human glioblastoma multiforme
    • Morrison R, Yamaguchi F, Bruner JM, Tang M, McKeehan W, Berger MS (1994) Fibroblast growth factor receptor gene expression and immunoreactivity are elevated in human glioblastoma multiforme. Cancer Res 54: 2794-2799
    • (1994) Cancer Res , vol.54 , pp. 2794-2799
    • Morrison, R.1    Yamaguchi, F.2    Bruner, J.M.3    Tang, M.4    McKeehan, W.5    Berger, M.S.6
  • 210
    • 0025959146 scopus 로고
    • Suppression of basic fibroblast growth factor expression by antisense oligonucleotides inhibits the growth of transformed human astrocytes
    • Morrison RS (1991) Suppression of basic fibroblast growth factor expression by antisense oligonucleotides inhibits the growth of transformed human astrocytes. J Biol Chem 266: 728-734
    • (1991) J Biol Chem , vol.266 , pp. 728-734
    • Morrison, R.S.1
  • 212
    • 0028341678 scopus 로고
    • Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas
    • Morrison RS, Yamaguchi F, Saya H, Bruner JM, Yahanda AM, Donehower LA, Berger M (1994) Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas. J Neurooncol 18: 207-216
    • (1994) J Neurooncol , vol.18 , pp. 207-216
    • Morrison, R.S.1    Yamaguchi, F.2    Saya, H.3    Bruner, J.M.4    Yahanda, A.M.5    Donehower, L.A.6    Berger, M.7
  • 214
    • 0031961980 scopus 로고    scopus 로고
    • Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor
    • Moscatello DK, Holgado-Madruga M, Emlet DR, Montgomery RB, Wong AJ (1998) Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor. J Biol Chem 273: 200-206
    • (1998) J Biol Chem , vol.273 , pp. 200-206
    • Moscatello, D.K.1    Holgado-Madruga, M.2    Emlet, D.R.3    Montgomery, R.B.4    Wong, A.J.5
  • 216
    • 0029068339 scopus 로고
    • Hypoxic induction of human vascular endothelial growth factor expression through c-src activation
    • Mukhopadhyay D, Tslokas L, Zhou X-M, Foster D, Brugge JS, Sukhatme VP (1995) Hypoxic induction of human vascular endothelial growth factor expression through c-src activation. Nature 375: 577-580
    • (1995) Nature , vol.375 , pp. 577-580
    • Mukhopadhyay, D.1    Tslokas, L.2    Zhou, X.-M.3    Foster, D.4    Brugge, J.S.5    Sukhatme, V.P.6
  • 217
    • 0029665883 scopus 로고    scopus 로고
    • Structural analysis of p185c-neu and epidermal growth factor receptor tyrosine kinases: Oligomerization of kinase domains
    • Murali R, Brennan PJ, Kieber-Emmons T, Greene MI (1996) Structural analysis of p185c-neu and epidermal growth factor receptor tyrosine kinases: oligomerization of kinase domains. Proc Natl Acad Sci USA 93: 6252-6257
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6252-6257
    • Murali, R.1    Brennan, P.J.2    Kieber-Emmons, T.3    Greene, M.I.4
  • 218
    • 0026695536 scopus 로고
    • Phosphorothioate antisense oligonucleotides against basic fibroblast growth factor inhibit anchorage-dependent and anchorage-independent growth of a malignant glioblastoma cell line
    • Murphy PR, Sato Y, Knee RS (1992) Phosphorothioate antisense oligonucleotides against basic fibroblast growth factor inhibit anchorage-dependent and anchorage-independent growth of a malignant glioblastoma cell line. Mol Endocrinol 6: 877-884
    • (1992) Mol Endocrinol , vol.6 , pp. 877-884
    • Murphy, P.R.1    Sato, Y.2    Knee, R.S.3
  • 219
    • 0029961912 scopus 로고    scopus 로고
    • A common mutant epidermal growth factor receptor confers enhanced tumourigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis
    • Nagane M, Coufal F, Lin H, Bogler O, Cavenee WK, Huang HJ (1996) A common mutant epidermal growth factor receptor confers enhanced tumourigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis. Cancer Res 56: 5079-5086
    • (1996) Cancer Res , vol.56 , pp. 5079-5086
    • Nagane, M.1    Coufal, F.2    Lin, H.3    Bogler, O.4    Cavenee, W.K.5    Huang, H.J.6
  • 220
    • 0032510679 scopus 로고    scopus 로고
    • Drug resistance of human glioblastoma cells conferred by a tumour-specific mutant epidermal growth factor receptor through modulation of bcl-XL and caspase-3-like proteases
    • Nagane M, Levitzki A, Gazit A, Cavenee WK, Huang HS (1998) Drug resistance of human glioblastoma cells conferred by a tumour-specific mutant epidermal growth factor receptor through modulation of bcl-XL and caspase-3-like proteases. Proc Natl Acad Sci USA 95: 5724-5729
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5724-5729
    • Nagane, M.1    Levitzki, A.2    Gazit, A.3    Cavenee, W.K.4    Huang, H.S.5
  • 221
    • 0029151472 scopus 로고
    • Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas
    • Nakano A, Tani E, Miyazaki K, Yamamoto Y, Furuyama J (1995) Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas. J Neurosurg 83: 298-307
    • (1995) J Neurosurg , vol.83 , pp. 298-307
    • Nakano, A.1    Tani, E.2    Miyazaki, K.3    Yamamoto, Y.4    Furuyama, J.5
  • 222
    • 0026475653 scopus 로고
    • Expression of c-kit receptor in normal and transformed human non-lymphoid tissues
    • Natali PG, Nicotra MR, Sures I, Santoro E, Bigotti A, Ullrich A (1992) Expression of c-kit receptor in normal and transformed human non-lymphoid tissues. Cancer Res 52: 6139-6143
    • (1992) Cancer Res , vol.52 , pp. 6139-6143
    • Natali, P.G.1    Nicotra, M.R.2    Sures, I.3    Santoro, E.4    Bigotti, A.5    Ullrich, A.6
  • 223
    • 9044235586 scopus 로고    scopus 로고
    • Cytoplasmic localization of EGF receptor in papillary thyroid carcinomas: Association with the 150-kDa receptor form
    • Ness GO, Haugen DR, Varhaug JE, Akslen LA, Lillehaug JR (1996) Cytoplasmic localization of EGF receptor in papillary thyroid carcinomas: association with the 150-kDa receptor form. Int J Cancer 65: 161-167
    • (1996) Int J Cancer , vol.65 , pp. 161-167
    • Ness, G.O.1    Haugen, D.R.2    Varhaug, J.E.3    Akslen, L.A.4    Lillehaug, J.R.5
  • 225
    • 0026045167 scopus 로고
    • Differential expression platelet-derived growth factor receptors in human malignant glioma cell lines
    • Nister M, Claesson-Welsh L, Eriksson A, Heldin CH, Westermark B (1991) Differential expression platelet-derived growth factor receptors in human malignant glioma cell lines. J Biol Chem: 266: 16755-16763
    • (1991) J Biol Chem , vol.266 , pp. 16755-16763
    • Nister, M.1    Claesson-Welsh, L.2    Eriksson, A.3    Heldin, C.H.4    Westermark, B.5
  • 226
    • 0023908964 scopus 로고
    • A glioma-derived pdgf a chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets
    • Nister M, Hammacher A, Mellstrom K, Siegbahn A, Ronnstrand L, Westermark B, Heldin CH (1988) A glioma-derived PDGF A chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets. Cell 52: 791-799
    • (1988) Cell , vol.52 , pp. 791-799
    • Nister, M.1    Hammacher, A.2    Mellstrom, K.3    Siegbahn, A.4    Ronnstrand, L.5    Westermark, B.6    Heldin, C.H.7
  • 227
    • 0023747564 scopus 로고
    • Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines
    • Nister M, Libermann TA, Betsholtz C, Pettersson M, Claesson-Welsh L, Heldin CH, Schlessinger J et al (1988) Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines. Cancer Res 48: 3910-3918
    • (1988) Cancer Res , vol.48 , pp. 3910-3918
    • Nister, M.1    Libermann, T.A.2    Betsholtz, C.3    Pettersson, M.4    Claesson-Welsh, L.5    Heldin, C.H.6    Schlessinger, J.7
  • 228
    • 0027955365 scopus 로고
    • Specific inhibition of c-sis protein synthesis and cell proliferation with antisense oligodeoxynucleotides in human glioma cells
    • Nitta T, Sato K (1994) Specific inhibition of c-sis protein synthesis and cell proliferation with antisense oligodeoxynucleotides in human glioma cells. Neurosurgery 34: 309-315
    • (1994) Neurosurgery , vol.34 , pp. 309-315
    • Nitta, T.1    Sato, K.2
  • 229
    • 0024282573 scopus 로고
    • Platelet-derived growth factor promotes division and motility and inhibitspremature differentiation of the oligodendrocyte/type-2 astrocyte progenitor cell
    • Noble M, Murray K, Stroobant P, Waterfield MD, Riddle P (1988) Platelet-derived growth factor promotes division and motility and inhibitspremature differentiation of the oligodendrocyte/type-2 astrocyte progenitor cell. Nature 333: 560-562
    • (1988) Nature , vol.333 , pp. 560-562
    • Noble, M.1    Murray, K.2    Stroobant, P.3    Waterfield, M.D.4    Riddle, P.5
  • 230
    • 0027432244 scopus 로고
    • Comparison of insulin-like growth factors and their binding proteins in glioblastoma and neuroblastoma cells
    • Nordqvist AC, Skwirut CC, Ehrenborg E, Grissom FE, Sara VR (1993) Comparison of insulin-like growth factors and their binding proteins in glioblastoma and neuroblastoma cells. Ann N Y Acad Sci 692: 297-299
    • (1993) Ann N Y Acad Sci , vol.692 , pp. 297-299
    • Nordqvist, A.C.1    Skwirut, C.C.2    Ehrenborg, E.3    Grissom, F.E.4    Sara, V.R.5
  • 231
    • 9044251968 scopus 로고    scopus 로고
    • Growth inhibition of human colon carcinoma cells by combinations of anti-epidermal growth factor-related growth factor antisense oligonucleotides
    • Normanno N, Bianco C, Damiano V, de A, E., Selvam MP, Grassi M, Magliulo G et al (1996) Growth Inhibition of Human Colon Carcinoma Cells by Combinations of Anti-Epidermal Growth Factor-related Growth Factor Antisense Oligonucleotides. Clin Cancer Res 2: 601-609
    • (1996) Clin Cancer Res , vol.2 , pp. 601-609
    • Normanno, N.1    Bianco, C.2    Damiano, V.3    De, A.E.4    Selvam, M.P.5    Grassi, M.6    Magliulo, G.7
  • 232
    • 15144341822 scopus 로고    scopus 로고
    • Inhibition of a naturally occurring EGFR oncoprotein by the p185neu ectodomain: Implications for subdomain contributions to receptor assembly
    • O'Rourke DM, Nute EJ, Davis JG, Wu C, Lee A, Murali R, Zhang HT et al (1998) Inhibition of a naturally occurring EGFR oncoprotein by the p185neu ectodomain: implications for subdomain contributions to receptor assembly. Oncogene 16: 1197-1207
    • (1998) Oncogene , vol.16 , pp. 1197-1207
    • O'Rourke, D.M.1    Nute, E.J.2    Davis, J.G.3    Wu, C.4    Lee, A.5    Murali, R.6    Zhang, H.T.7
  • 234
    • 0023815683 scopus 로고
    • Synthesis and assembly of a functionally active recombinant platelet-derived growth factor AB heterodimer
    • Ostman A, Rall L, Hammacher A, Wormstead MA, Coit D, Valenzuela P, Betsholtz C et al (1988) Synthesis and assembly of a functionally active recombinant platelet-derived growth factor AB heterodimer. J Biol Chem 263: 16202-16208
    • (1988) J Biol Chem , vol.263 , pp. 16202-16208
    • Ostman, A.1    Rall, L.2    Hammacher, A.3    Wormstead, M.A.4    Coit, D.5    Valenzuela, P.6    Betsholtz, C.7
  • 235
    • 0021798948 scopus 로고
    • Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture
    • Pantazis P, Pelicci PG, Dalla-Favera R, Antoniades HN (1985) Synthesis and secretion of proteins resembling platelet-derived growth factor by human glioblastoma and fibrosarcoma cells in culture. Proc Natl Acad Sci USA 82: 2404-2408
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 2404-2408
    • Pantazis, P.1    Pelicci, P.G.2    Dalla-Favera, R.3    Antoniades, H.N.4
  • 236
    • 0028351179 scopus 로고
    • Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-alpha, bFGF, IL-2] on glioma spheroid growth, migration and invasion
    • Pedersen PH, Ness GO, Engebraaten O, Bjerkvig R, Lillehaug JR, Laerum OD (1994) Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-alpha, bFGF, IL-2] on glioma spheroid growth, migration and invasion. Int J Cancer 56: 255-261
    • (1994) Int J Cancer , vol.56 , pp. 255-261
    • Pedersen, P.H.1    Ness, G.O.2    Engebraaten, O.3    Bjerkvig, R.4    Lillehaug, J.R.5    Laerum, O.D.6
  • 237
    • 0026776424 scopus 로고
    • Isolation of the neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumour cells
    • Peles E, Bacus SS, Koski RA, Lu HS, Wen D, Ogden SG, Levy RB et al (1992) Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumour cells. Cell 69: 205-216
    • (1992) Cell , vol.69 , pp. 205-216
    • Peles, E.1    Bacus, S.S.2    Koski, R.A.3    Lu, H.S.4    Wen, D.5    Ogden, S.G.6    Levy, R.B.7
  • 238
    • 0027053487 scopus 로고
    • Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
    • Pepper MS, Ferrara N, Orci L, Montesano R (1992) Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Commun 189: 824-831
    • (1992) Biochem Biophys Res Commun , vol.189 , pp. 824-831
    • Pepper, M.S.1    Ferrara, N.2    Orci, L.3    Montesano, R.4
  • 239
    • 0023410819 scopus 로고
    • Activated neu oncogene sequences in primary tumours of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosurea
    • Perantoni AO, Rice JM, Reed CD, Watatani M, Wenk ML (1987) Activated neu oncogene sequences in primary tumours of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosurea. Proc Natl Acad Sci 84: 6317-6321
    • (1987) Proc Natl Acad Sci , vol.84 , pp. 6317-6321
    • Perantoni, A.O.1    Rice, J.M.2    Reed, C.D.3    Watatani, M.4    Wenk, M.L.5
  • 240
    • 0027424647 scopus 로고
    • Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth
    • Peters KG, De Vries C, Williams LT (1993) Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth. Proc Natl Acad Sci USA 90: 8915-8919
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8915-8919
    • Peters, K.G.1    De Vries, C.2    Williams, L.T.3
  • 241
    • 0028080990 scopus 로고
    • c phosphorylation and activation of the IGF-I receptor in src-transformed cells
    • Peterson JE, Jelinek T, Kaleko M, Siddle K, Weber MJ (1994) c phosphorylation and activation of the IGF-I receptor in src-transformed cells. J Biol Chem 269: 27315-27321
    • (1994) J Biol Chem , vol.269 , pp. 27315-27321
    • Peterson, J.E.1    Jelinek, T.2    Kaleko, M.3    Siddle, K.4    Weber, M.J.5
  • 242
    • 0031946469 scopus 로고    scopus 로고
    • Magnetic resonance imaging detects suppression of tumour vascular permeability after administration of antibody to vascular endothelial growth factor
    • Pham CD, Roberts TP, van Bruggen N, Melnyk O, Mann J, Ferrara N, Cohen RL et al (1998) Magnetic resonance imaging detects suppression of tumour vascular permeability after administration of antibody to vascular endothelial growth factor. Cancer Invest 16: 225-230
    • (1998) Cancer Invest , vol.16 , pp. 225-230
    • Pham, C.D.1    Roberts, T.P.2    Van Bruggen, N.3    Melnyk, O.4    Mann, J.5    Ferrara, N.6    Cohen, R.L.7
  • 243
    • 0027196461 scopus 로고
    • Intense local expression of vascular endothelial growth factor mRNA in human intracranial neoplasms: Association with regions of necrosis
    • Phillips HS, Armani MP, Stavrou D, Ferrara N, Westphal M (1993) Intense local expression of vascular endothelial growth factor mRNA in human intracranial neoplasms: association with regions of necrosis. Int J Oncol 2: 913-919
    • (1993) Int J Oncol , vol.2 , pp. 913-919
    • Phillips, H.S.1    Armani, M.P.2    Stavrou, D.3    Ferrara, N.4    Westphal, M.5
  • 244
    • 0028179159 scopus 로고
    • Transforming growth factor-alpha-pseudomonas exotoxin fusion protein (TGF-alpha-PE38) treatment of subcutaneous and intracranial human glioma and medulloblastoma xenografts in athymic mice
    • Phillips PC, Levow C, Catterall M, Colvin OM, Pastan I, Brem H (1994) Transforming growth factor-alpha-Pseudomonas exotoxin fusion protein (TGF-alpha-PE38) treatment of subcutaneous and intracranial human glioma and medulloblastoma xenografts in athymic mice. Cancer Res 54: 1008-1015
    • (1994) Cancer Res , vol.54 , pp. 1008-1015
    • Phillips, P.C.1    Levow, C.2    Catterall, M.3    Colvin, O.M.4    Pastan, I.5    Brem, H.6
  • 245
    • 0026663164 scopus 로고
    • Roles of insulinlike growth factor 1 (IGF-I) and the IGF-1 receptor in epidermal growth factor-stimulated growth of 3T3 cells
    • Pietrzkowski Z, Sell C, Lammers R, Ullrich A, Baserga R (1992) Roles of insulinlike growth factor 1 (IGF-I) and the IGF-1 receptor in epidermal growth factor-stimulated growth of 3T3 cells. Mol Cell Biol 12: 3883-3889
    • (1992) Mol Cell Biol , vol.12 , pp. 3883-3889
    • Pietrzkowski, Z.1    Sell, C.2    Lammers, R.3    Ullrich, A.4    Baserga, R.5
  • 247
    • 0027297904 scopus 로고
    • Expression of epidermal growth factor receptor in human glioblastoma multiforme
    • Pigott TJ, Robson DK, Palmer J, Ward LM (1993) Expression of epidermal growth factor receptor in human glioblastoma multiforme. Br J Neurosurg 7: 261-265
    • (1993) Br J Neurosurg , vol.7 , pp. 261-265
    • Pigott, T.J.1    Robson, D.K.2    Palmer, J.3    Ward, L.M.4
  • 248
    • 0031465112 scopus 로고    scopus 로고
    • Differential expression of NDF/neuregulin receptors ErbB-3 and ErbB-4 and involvement in inhibition of neuronal differentiation
    • Pinkas-Kramarski R, Eilam R, Alroy I, Levkowitz G, Lonai P, Yarden Y (1997) Differential expression of NDF/neuregulin receptors ErbB-3 and ErbB-4 and involvement in inhibition of neuronal differentiation. Oncogene 15: 2803-2815
    • (1997) Oncogene , vol.15 , pp. 2803-2815
    • Pinkas-Kramarski, R.1    Eilam, R.2    Alroy, I.3    Levkowitz, G.4    Lonai, P.5    Yarden, Y.6
  • 249
    • 0028031085 scopus 로고
    • Brain neurons and glial cells express neu differentiation factor/heregulin: A survival factor for astrocytes
    • Pinkas-Kramarski R, Eilam R, Spiegler O, Lavi S, Liu N, Chang D, Wen D et al (1994) Brain neurons and glial cells express Neu differentiation factor/heregulin: a survival factor for astrocytes. Proc Natl Acad Sci USA 91: 9387-9391
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9387-9391
    • Pinkas-Kramarski, R.1    Eilam, R.2    Spiegler, O.3    Lavi, S.4    Liu, N.5    Chang, D.6    Wen, D.7
  • 250
    • 2142843806 scopus 로고    scopus 로고
    • Diversification of neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
    • Pinkas-Kramarski R, Soussan L, Waterman H, Levkowitz G, Alroy I, Klapper L, Lavi S et al (1996) Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J 15: 2452-2467
    • (1996) EMBO J , vol.15 , pp. 2452-2467
    • Pinkas-Kramarski, R.1    Soussan, L.2    Waterman, H.3    Levkowitz, G.4    Alroy, I.5    Klapper, L.6    Lavi, S.7
  • 251
    • 0026439870 scopus 로고
    • Platelet-derived growth factor receptor-beta is induced during tumour development and upregulated during tumour progression in endothelial cells in human gliomas
    • Plate KH, Breier G, Farrell CL, Risau W (1992) Platelet-derived growth factor receptor-beta is induced during tumour development and upregulated during tumour progression in endothelial cells in human gliomas. Lab Invest 67: 529-534
    • (1992) Lab Invest , vol.67 , pp. 529-534
    • Plate, K.H.1    Breier, G.2    Farrell, C.L.3    Risau, W.4
  • 252
    • 0027432324 scopus 로고
    • Upregulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumour angiogenesis
    • Plate KH, Breier G, Millauer B, Ullrich A, Risau W (1993) Upregulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumour angiogenesis. Cancer Res 53: 5822-5827
    • (1993) Cancer Res , vol.53 , pp. 5822-5827
    • Plate, K.H.1    Breier, G.2    Millauer, B.3    Ullrich, A.4    Risau, W.5
  • 253
    • 0028090642 scopus 로고
    • Vascular endothelial growth factor and glioma angiogenesis: Coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms
    • Plate KH, Breier G, Weich HA, Mennel HD, Risau W (1994) Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms. Int J Cancer 59: 520-529
    • (1994) Int J Cancer , vol.59 , pp. 520-529
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Mennel, H.D.4    Risau, W.5
  • 254
    • 0026446102 scopus 로고
    • Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
    • Plate KH, Breier G, Weich HA, Risau W (1992) Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359: 845-848
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breier, G.2    Weich, H.A.3    Risau, W.4
  • 255
    • 0029397222 scopus 로고
    • Angiogenesis in malignant gliomas
    • Plate KH, Risau W (1995) Angiogenesis in malignant gliomas. Glia 15: 339-347
    • (1995) Glia , vol.15 , pp. 339-347
    • Plate, K.H.1    Risau, W.2
  • 256
    • 0030772252 scopus 로고    scopus 로고
    • Vascular endothelial growth factor
    • Plate KH, Warnke PC (1997) Vascular endothelial growth factor. J Neurooncol 35: 365-372
    • (1997) J Neurooncol , vol.35 , pp. 365-372
    • Plate, K.H.1    Warnke, P.C.2
  • 258
    • 0025780988 scopus 로고
    • Response of low-passage human malignant gliomas in vitro to stimulation and selective inhibition of growth factor-mediated pathways
    • Pollack IF, Randall MS, Kristofik MP, Kelly RH, Selker RG, Vertosick FTJ (1991) Response of low-passage human malignant gliomas in vitro to stimulation and selective inhibition of growth factor-mediated pathways. J Neurosurg 75: 284-293
    • (1991) J Neurosurg , vol.75 , pp. 284-293
    • Pollack, I.F.1    Randall, M.S.2    Kristofik, M.P.3    Kelly, R.H.4    Selker, R.G.5    Vertosick, F.T.J.6
  • 259
    • 0030066455 scopus 로고    scopus 로고
    • Platelet-derived growth factor-B/v-sis confers a tumourigenic and metastatic phenotype to human t98G glioblastoma cells
    • Potapova O, Fakhrai H, Baird S, Mercola D (1996) Platelet-derived growth factor-B/v-sis confers a tumourigenic and metastatic phenotype to human T98G glioblastoma cells. Cancer Res 56: 280-286
    • (1996) Cancer Res , vol.56 , pp. 280-286
    • Potapova, O.1    Fakhrai, H.2    Baird, S.3    Mercola, D.4
  • 260
    • 0029938496 scopus 로고    scopus 로고
    • Growth factor PDGF-B/v-sis confers a tumourigenic phenotype to human tumour cells bearing PDGF receptors but not to cells devoid of receptors: Evidence for an autocrine, but not a paracrine, mechanism
    • Potapova O, Fakhrai H, Mercola D (1996) Growth factor PDGF-B/v-sis confers a tumourigenic phenotype to human tumour cells bearing PDGF receptors but not to cells devoid of receptors: evidence for an autocrine, but not a paracrine, mechanism. Int J Cancer 66: 669-677
    • (1996) Int J Cancer , vol.66 , pp. 669-677
    • Potapova, O.1    Fakhrai, H.2    Mercola, D.3
  • 261
    • 0028265209 scopus 로고
    • Dominant negative inhibition of tumourigenesis in vivo by human insulin-like growth factor I receptor mutant
    • Prager D, Li HL, Asa S, Melmed S (1994) Dominant negative inhibition of tumourigenesis in vivo by human insulin-like growth factor I receptor mutant. Proc Natl Acad Sci USA 91: 2181-2185
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2181-2185
    • Prager, D.1    Li, H.L.2    Asa, S.3    Melmed, S.4
  • 262
    • 0029815093 scopus 로고    scopus 로고
    • Enhanced tumourigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway
    • Prigent SA, Nagane M, Lin H, Huvar I, Boss GR, Feramisco JR, Cavenee WK et al (1996) Enhanced tumourigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway. J Biol Chem 271: 25639-25645
    • (1996) J Biol Chem , vol.271 , pp. 25639-25645
    • Prigent, S.A.1    Nagane, M.2    Lin, H.3    Huvar, I.4    Boss, G.R.5    Feramisco, J.R.6    Cavenee, W.K.7
  • 263
    • 0024462063 scopus 로고
    • PDGF A chain homodimers drive proliferation of bipotential (O-2A) glial progenitor cells in the developing rat optic nerve
    • Pringle N, Collarini EJ, Mosley MJ, Heldin CH, Westermark B, Richardson WD (1989) PDGF A chain homodimers drive proliferation of bipotential (O-2A) glial progenitor cells in the developing rat optic nerve. EMBO J 8: 1049-1056
    • (1989) EMBO J , vol.8 , pp. 1049-1056
    • Pringle, N.1    Collarini, E.J.2    Mosley, M.J.3    Heldin, C.H.4    Westermark, B.5    Richardson, W.D.6
  • 264
    • 0023989811 scopus 로고
    • Primary structure of c-kit: Relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus
    • Qiu FH, Ray P, Brown K, Barker PE, Jhanwar S, Ruddle FH, Besmer P (1988) Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus. EMBO J 7: 1003-1011
    • (1988) EMBO J , vol.7 , pp. 1003-1011
    • Qiu, F.H.1    Ray, P.2    Brown, K.3    Barker, P.E.4    Jhanwar, S.5    Ruddle, F.H.6    Besmer, P.7
  • 265
    • 0027249239 scopus 로고
    • Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
    • Quinn TP, Peters KG, De Vries C, Ferrara N, Williams LT (1993) Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci USA 90: 7533-7537
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7533-7537
    • Quinn, T.P.1    Peters, K.G.2    De Vries, C.3    Ferrara, N.4    Williams, L.T.5
  • 266
    • 0024282594 scopus 로고
    • Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture
    • Raff MC, Lillien LE, Richardson WD, Burne JF, Noble MD (1988) Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature 333: 562-565
    • (1988) Nature , vol.333 , pp. 562-565
    • Raff, M.C.1    Lillien, L.E.2    Richardson, W.D.3    Burne, J.F.4    Noble, M.D.5
  • 267
    • 0030806772 scopus 로고    scopus 로고
    • Prognostic factors in malignant glioma: Influence of the overexpression of oncogene and tumour-suppressor gene products on survival
    • Rainov NG, Dobberstein KU, Bahn H, Holzhausen HJ, Lautenschlager C, Heidecke V, Burkert W (1997) Prognostic factors in malignant glioma: influence of the overexpression of oncogene and tumour-suppressor gene products on survival. J Neurooncol 35: 13-28
    • (1997) J Neurooncol , vol.35 , pp. 13-28
    • Rainov, N.G.1    Dobberstein, K.U.2    Bahn, H.3    Holzhausen, H.J.4    Lautenschlager, C.5    Heidecke, V.6    Burkert, W.7
  • 268
    • 0028861548 scopus 로고
    • Transfection with bFGF sense and antisense cDNA resulting in modification of malignant glioma growth
    • Redekop GJ, Naus CC (1995) Transfection with bFGF sense and antisense cDNA resulting in modification of malignant glioma growth. J Neurosurg 82: 83-90
    • (1995) J Neurosurg , vol.82 , pp. 83-90
    • Redekop, G.J.1    Naus, C.C.2
  • 269
    • 0029026107 scopus 로고
    • Tumour-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: Use of the tyramine-cellobiose radio-iodination method enhances cellular retention and uptake in tumour xenografts
    • Reist CJ, Archer GE, Kurpad SN, Wikstrand CJ, Vaidyanathan G, Willingham MC, Moscatello DK et al (1995) Tumour-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: use of the tyramine-cellobiose radio-iodination method enhances cellular retention and uptake in tumour xenografts. Cancer Res 55: 4375-4382
    • (1995) Cancer Res , vol.55 , pp. 4375-4382
    • Reist, C.J.1    Archer, G.E.2    Kurpad, S.N.3    Wikstrand, C.J.4    Vaidyanathan, G.5    Willingham, M.C.6    Moscatello, D.K.7
  • 270
    • 0031959117 scopus 로고    scopus 로고
    • The role of the insulin-like growth factor I receptor in transformation and apoptosis
    • Resnicoff M, Baserga R (1998) The role of the insulin-like growth factor I receptor in transformation and apoptosis. Ann N Y Acad Sci 842: 76-81
    • (1998) Ann N Y Acad Sci , vol.842 , pp. 76-81
    • Resnicoff, M.1    Baserga, R.2
  • 271
    • 0029096782 scopus 로고
    • Correlation between apoptosis, tumourigenesis, and levels of insulin-like growth factor I receptors
    • Resnicoff M, Burgaud JL, Rotman HL, Abraham D, Baserga R (1995) Correlation between apoptosis, tumourigenesis, and levels of insulin-like growth factor I receptors. Cancer Res 55: 3739-3741
    • (1995) Cancer Res , vol.55 , pp. 3739-3741
    • Resnicoff, M.1    Burgaud, J.L.2    Rotman, H.L.3    Abraham, D.4    Baserga, R.5
  • 272
    • 0028050256 scopus 로고
    • Growth inhibition of human melanoma cells in nude mice by antisense strategies to the type 1 insulin-like growth factor receptor
    • Resnicoff M, Coppola D, Sell C, Rubin R, Ferrone S, Baserga R (1994) Growth inhibition of human melanoma cells in nude mice by antisense strategies to the type 1 insulin-like growth factor receptor. Cancer Res 54: 4848-4850
    • (1994) Cancer Res , vol.54 , pp. 4848-4850
    • Resnicoff, M.1    Coppola, D.2    Sell, C.3    Rubin, R.4    Ferrone, S.5    Baserga, R.6
  • 273
    • 0030029754 scopus 로고    scopus 로고
    • Inhibition of rat C6 glioblastoma tumour growth by expression of insulin-like growth factor I receptor antisense mRNA
    • Resnicoff M, Li W, Basak S, Herlyn D, Baserga R, Rubin R (1996) Inhibition of rat C6 glioblastoma tumour growth by expression of insulin-like growth factor I receptor antisense mRNA. Cancer Immunol Immunother 42: 64-68
    • (1996) Cancer Immunol Immunother , vol.42 , pp. 64-68
    • Resnicoff, M.1    Li, W.2    Basak, S.3    Herlyn, D.4    Baserga, R.5    Rubin, R.6
  • 274
    • 0028271497 scopus 로고
    • Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumourigenic and induce regression of wild-type tumours
    • Resnicoff M, Sell C, Rubini M, Coppola D, Ambrose D, Baserga R, Rubin R (1994) Rat glioblastoma cells expressing an antisense RNA to the insulin-like growth factor-1 (IGF-1) receptor are nontumourigenic and induce regression of wild-type tumours. Cancer Res 54: 2218-2222
    • (1994) Cancer Res , vol.54 , pp. 2218-2222
    • Resnicoff, M.1    Sell, C.2    Rubini, M.3    Coppola, D.4    Ambrose, D.5    Baserga, R.6    Rubin, R.7
  • 275
    • 0023947394 scopus 로고
    • A role for platelet-derived growth factor in normal gliogenesis in the central nervous system
    • Richardson WD, Pringle N, Mosley MJ, Westermark B, Dubois-Dalcq M (1988) A role for platelet-derived growth factor in normal gliogenesis in the central nervous system. Cell 53: 309-319
    • (1988) Cell , vol.53 , pp. 309-319
    • Richardson, W.D.1    Pringle, N.2    Mosley, M.J.3    Westermark, B.4    Dubois-Dalcq, M.5
  • 276
    • 0029118223 scopus 로고
    • The cellular response to neuregulins is governed by complex interactions of the erbb receptor family
    • Riese DJn, van Raaij TM, Plowman GD, Andrews GC, Stern DF (1995) The cellular response to neuregulins is governed by complex interactions of the erbB receptor family. Mol Cell Biol 15: 5770-5576
    • (1995) Mol Cell Biol , vol.15 , pp. 5770-15576
    • Riese, D.Jn.1    Van Raaij, T.M.2    Plowman, G.D.3    Andrews, G.C.4    Stern, D.F.5
  • 277
    • 0028276786 scopus 로고
    • Invasiveness and metastasis of NIH 3T3 cells induced by met-hepatocyte growth factor/scatter factor autocrine stimulation
    • Rong S, Segal S, Anver M, Resau JH, Vande-Woude GF (1994) Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. Proc Natl Acad Sci USA 91: 4731-4735
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4731-4735
    • Rong, S.1    Segal, S.2    Anver, M.3    Resau, J.H.4    Vande-Woude, G.F.5
  • 279
    • 0022481299 scopus 로고
    • Expression in rat fibroblasts of a human transforming growth factor-alpha cDNA results in transformation
    • Rosenthal A, Lindquist PB, Bringman TS, Goeddel DV, Derynck R (1986) Expression in rat fibroblasts of a human transforming growth factor-alpha cDNA results in transformation. Cell 46: 301-309
    • (1986) Cell , vol.46 , pp. 301-309
    • Rosenthal, A.1    Lindquist, P.B.2    Bringman, T.S.3    Goeddel, D.V.4    Derynck, R.5
  • 280
    • 0029119731 scopus 로고
    • Insulin-like growth factor-I receptor. Its role in cell proliferation, apoptosis, and tumourigenicity
    • Rubin R, Baserga R (1995) Insulin-like growth factor-I receptor. Its role in cell proliferation, apoptosis, and tumourigenicity. Lab Invest 73: 311-331
    • (1995) Lab Invest , vol.73 , pp. 311-331
    • Rubin, R.1    Baserga, R.2
  • 281
    • 0030029271 scopus 로고    scopus 로고
    • Inhibition of growth of c6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence
    • Saleh M, Stacker SA, Wilks AF (1996) Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence. Cancer Res 56: 393-401
    • (1996) Cancer Res , vol.56 , pp. 393-401
    • Saleh, M.1    Stacker, S.A.2    Wilks, A.F.3
  • 282
    • 0028920358 scopus 로고
    • Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumours
    • Samoto K, Ikezaki K, Ono M, Shono T, Kohno K, Kuwano M, Fukui M (1995) Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumours. Cancer Res 55: 1189-1193
    • (1995) Cancer Res , vol.55 , pp. 1189-1193
    • Samoto, K.1    Ikezaki, K.2    Ono, M.3    Shono, T.4    Kohno, K.5    Kuwano, M.6    Fukui, M.7
  • 283
    • 0023768544 scopus 로고
    • The expression of insulin-like growth factor I and insulin-like growth factor II genes in the human fetal and adult brain and in glioma
    • Sandberg AC, Engberg C, Lake M, von Holst H, Sara VR (1988) The expression of insulin-like growth factor I and insulin-like growth factor II genes in the human fetal and adult brain and in glioma. Neurosci Lett 93: 114-119
    • (1988) Neurosci Lett , vol.93 , pp. 114-119
    • Sandberg, A.C.1    Engberg, C.2    Lake, M.3    Von Holst, H.4    Sara, V.R.5
  • 285
    • 0021800248 scopus 로고
    • Characterization of cultured rat oligodendrocytes proliferating in a serum-free, chemically defined medium
    • Saneto RP, de Vellis J (1985) Characterization of cultured rat oligodendrocytes proliferating in a serum-free, chemically defined medium. Proc Natl Acad Sci USA 82: 3509-2313
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 3509-12313
    • Saneto, R.P.1    De Vellis, J.2
  • 286
    • 0023759912 scopus 로고
    • The role of the insulin-like growth factors in the regulation of brain development
    • Sara VR, Carlsson-Skwirut C (1988) The role of the insulin-like growth factors in the regulation of brain development. Prog Brain Res 73: 87-99
    • (1988) Prog Brain Res , vol.73 , pp. 87-99
    • Sara, V.R.1    Carlsson-Skwirut, C.2
  • 287
    • 0026551288 scopus 로고
    • Increased expression of genes from growth factor signaling pathways in glioblastoma cell lines
    • Saxena A, Ali IU (1992) Increased expression of genes from growth factor signaling pathways in glioblastoma cell lines. Oncogene 7: 243-247
    • (1992) Oncogene , vol.7 , pp. 243-247
    • Saxena, A.1    Ali, I.U.2
  • 289
    • 0028097815 scopus 로고
    • Amplification of the epidermal-growth-factor-receptor gene correlates with different growth behaviour in human glioblastoma
    • Schlegel J, Merdes A, Stumm G, Albert FK, Forsting M, Hynes N, Kiessling M (1994) Amplification of the epidermal-growth-factor-receptor gene correlates with different growth behaviour in human glioblastoma. Int J Cancer 56: 72-77
    • (1994) Int J Cancer , vol.56 , pp. 72-77
    • Schlegel, J.1    Merdes, A.2    Stumm, G.3    Albert, F.K.4    Forsting, M.5    Hynes, N.6    Kiessling, M.7
  • 292
    • 0032941495 scopus 로고    scopus 로고
    • Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis
    • Schmidt NO, Westphal M, Hagel C, Ergün S, Stavrou D, Rosen EM, Lamszus K (1999) Levels of Vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis. Int J Cancer 84: 10-18
    • (1999) Int J Cancer , vol.84 , pp. 10-18
    • Schmidt, N.O.1    Westphal, M.2    Hagel, C.3    Ergün, S.4    Stavrou, D.5    Rosen, E.M.6    Lamszus, K.7
  • 293
    • 0029146954 scopus 로고
    • EGFR gene amplification-rearrangement in human glioblastomas
    • Schwechheimer K, Huang S, Cavenee WK (1995) EGFR gene amplification-rearrangement in human glioblastomas. Int J Cancer 62: 145-148
    • (1995) Int J Cancer , vol.62 , pp. 145-148
    • Schwechheimer, K.1    Huang, S.2    Cavenee, W.K.3
  • 295
    • 0028798083 scopus 로고
    • A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF
    • Seetharam L, Gotoh N, Maru Y, Neufeld G, Yamaguchi S, Shibuya M (1995) A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF. Oncogene 10: 135-147
    • (1995) Oncogene , vol.10 , pp. 135-147
    • Seetharam, L.1    Gotoh, N.2    Maru, Y.3    Neufeld, G.4    Yamaguchi, S.5    Shibuya, M.6
  • 296
    • 0028568009 scopus 로고
    • Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma
    • Segal RA, Goumnerova LC, Kwon YK, Stiles CD, Pomeroy SL (1994) Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proc Natl Acad Sci USA 91: 12867-12871
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12867-12871
    • Segal, R.A.1    Goumnerova, L.C.2    Kwon, Y.K.3    Stiles, C.D.4    Pomeroy, S.L.5
  • 297
    • 0028852556 scopus 로고
    • Insulin-like growth factor I (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis
    • Sell C, Baserga R, Rubin R (1995) Insulin-like growth factor I (IGF-I) and the IGF-I receptor prevent etoposide-induced apoptosis. Cancer Res 55: 303-306
    • (1995) Cancer Res , vol.55 , pp. 303-306
    • Sell, C.1    Baserga, R.2    Rubin, R.3
  • 298
    • 0028332092 scopus 로고
    • Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts
    • Sell C, Dumenil G, Deveaud C, Miura M, Coppola D, DeAngelis T, Rubin R et al (1994) Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol Cell Biol 14: 3604-3612
    • (1994) Mol Cell Biol , vol.14 , pp. 3604-3612
    • Sell, C.1    Dumenil, G.2    Deveaud, C.3    Miura, M.4    Coppola, D.5    DeAngelis, T.6    Rubin, R.7
  • 299
    • 0027366338 scopus 로고
    • Simian virus 40 large tumour antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor
    • Sell C, Rubini M, Rubin R, Liu JP, Efstratiadis A, Baserga R (1993) Simian virus 40 large tumour antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. Proc Natl Acad Sci USA 90: 11217-11221
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11217-11221
    • Sell, C.1    Rubini, M.2    Rubin, R.3    Liu, J.P.4    Efstratiadis, A.5    Baserga, R.6
  • 300
    • 0028299339 scopus 로고
    • Glial growth factor restricts mammalian neural crest stem cells to a glial fate
    • Shah NM, Marchionni MA, Isaacs I, Stroobant P, Anderson DJ (1994) Glial growth factor restricts mammalian neural crest stem cells to a glial fate. Cell 77: 349-360
    • (1994) Cell , vol.77 , pp. 349-360
    • Shah, N.M.1    Marchionni, M.A.2    Isaacs, I.3    Stroobant, P.4    Anderson, D.J.5
  • 301
    • 0027361809 scopus 로고
    • Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells
    • Shamah SM, Stiles CD, Guha A (1993) Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells. Mol Cell Biol 13: 7203-7212
    • (1993) Mol Cell Biol , vol.13 , pp. 7203-7212
    • Shamah, S.M.1    Stiles, C.D.2    Guha, A.3
  • 302
    • 0031084896 scopus 로고    scopus 로고
    • Potential triple helix-mediated inhibition of IGF-I gene expression significantly reduces tumourigenicity of glioblastoma in an animal model
    • Shevelev A, Burfeind P, Schulze E, Rininsland F, Johnson TR, Trojan J, Chernicky CL et al (1997) Potential triple helix-mediated inhibition of IGF-I gene expression significantly reduces tumourigenicity of glioblastoma in an animal model. Cancer Gene Ther 4: 105-112
    • (1997) Cancer Gene Ther , vol.4 , pp. 105-112
    • Shevelev, A.1    Burfeind, P.2    Schulze, E.3    Rininsland, F.4    Johnson, T.R.5    Trojan, J.6    Chernicky, C.L.7
  • 303
    • 0025259592 scopus 로고
    • Nucleotide sequence and expression of a novel human receptor-tyrosine kinase (flt) closely related to the fms family
    • Shibuya M, Yamaguchi S, Yamane A, Ikeda T, Tojo A. Matsuhima H, Sato M (1990) Nucleotide sequence and expression of a novel human receptor-tyrosine kinase (flt) closely related to the fms family. Oncogene 5: 519-524
    • (1990) Oncogene , vol.5 , pp. 519-524
    • Shibuya, M.1    Yamaguchi, S.2    Yamane, A.3    Ikeda, T.4    Tojo, A.5    Matsuhima, H.6    Sato, M.7
  • 304
    • 0025830381 scopus 로고
    • Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human
    • Shimasaki S, Shimonaka M, Zhang HP, Ling N (1991) Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human. J Biol Chem 266: 10646-10653
    • (1991) J Biol Chem , vol.266 , pp. 10646-10653
    • Shimasaki, S.1    Shimonaka, M.2    Zhang, H.P.3    Ling, N.4
  • 305
    • 0028175757 scopus 로고
    • Association of the transmembrane TGF-alpha precursor with a protein kinase complex
    • Shum L, Reeves SA, Kuo AC, Fromer ES, Derynck R (1994) Association of the transmembrane TGF-alpha precursor with a protein kinase complex. J Cell Biol 125: 903-916
    • (1994) J Cell Biol , vol.125 , pp. 903-916
    • Shum, L.1    Reeves, S.A.2    Kuo, A.C.3    Fromer, E.S.4    Derynck, R.5
  • 306
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, Keshet E (1992) Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359: 843-845
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 307
    • 0028870050 scopus 로고
    • Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumour angiogenesis
    • Shweiki D, Neeman M, Itin A, Keshet E (1995) Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumour angiogenesis. Proc Natl Acad Sci USA 92: 768-772
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 768-772
    • Shweiki, D.1    Neeman, M.2    Itin, A.3    Keshet, E.4
  • 308
    • 0025502361 scopus 로고
    • Selective killing of tumour cells using EGF or TGF alpha-Pseudomonas exotoxin chimeric molecules
    • Siegall CB, FitzGerald DJ, Pastan I (1990) Selective killing of tumour cells using EGF or TGF alpha-Pseudomonas exotoxin chimeric molecules. Semin Cancer Biol 1: 345-350
    • (1990) Semin Cancer Biol , vol.1 , pp. 345-350
    • Siegall, C.B.1    Fitzgerald, D.J.2    Pastan, I.3
  • 309
    • 0027083325 scopus 로고
    • Anti-sense transforming growth factor alpha oligonucleotides inhibit autocrine stimulated proliferation of a colon carcinoma cell line
    • Sizeland AM, Burgess AW (1992) Anti-sense transforming growth factor alpha oligonucleotides inhibit autocrine stimulated proliferation of a colon carcinoma cell line. Mol Biol Cell 3: 1235-1243
    • (1992) Mol Biol Cell , vol.3 , pp. 1235-1243
    • Sizeland, A.M.1    Burgess, A.W.2
  • 310
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL (1987) Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235: 177-182
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 312
    • 0028302018 scopus 로고
    • ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor
    • Soltoff SP, Carraway KLr, Prigent SA, Gullick WG, Cantley LC (1994) ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Mol Cell Biol 14: 3550-3558
    • (1994) Mol Cell Biol , vol.14 , pp. 3550-3558
    • Soltoff, S.P.1    Carraway, K.Lr.2    Prigent, S.A.3    Gullick, W.G.4    Cantley, L.C.5
  • 313
    • 0029040021 scopus 로고
    • In vivo inhibition of angiogenesis and growth of the human U-87 malignant glial tumour by treatment with an antibody against basic fibroblast growth factor
    • Stan AC, Nemati MN, Pietsch T, Walter GF, Dietz H (1995) In vivo inhibition of angiogenesis and growth of the human U-87 malignant glial tumour by treatment with an antibody against basic fibroblast growth factor. J Neurosurgery 82: 1044-1052
    • (1995) J Neurosurgery , vol.82 , pp. 1044-1052
    • Stan, A.C.1    Nemati, M.N.2    Pietsch, T.3    Walter, G.F.4    Dietz, H.5
  • 314
    • 0028859225 scopus 로고
    • Coexpression of stem cell factor and its receptor c-kit in human malignant glioma cell lines
    • Stanulla M, Welte K, Hadam MR, Pietsch T (1995) Coexpression of stem cell factor and its receptor c-kit in human malignant glioma cell lines. Acta Neuropathol (Berl) 89: 158-165
    • (1995) Acta Neuropathol (Berl) , vol.89 , pp. 158-165
    • Stanulla, M.1    Welte, K.2    Hadam, M.R.3    Pietsch, T.4
  • 315
    • 0023791645 scopus 로고
    • Expression of an altered epidermal growth factor receptor by human glioblastoma cells
    • Steck PA, Lee P, Hung MC, Yung WK (1988) Expression of an altered epidermal growth factor receptor by human glioblastoma cells. Cancer Res 48: 5433-5439
    • (1988) Cancer Res , vol.48 , pp. 5433-5439
    • Steck, P.A.1    Lee, P.2    Hung, M.C.3    Yung, W.K.4
  • 316
    • 0026051419 scopus 로고
    • Acidic and basic fibroblast growth factors are present in glioblastoma multiforme
    • Stefanik DF, Rizkalla LR, Soi A, Goldblatt SA, Rizkalla WM (1991) Acidic and basic fibroblast growth factors are present in glioblastoma multiforme. Cancer Res 51: 5760-5765
    • (1991) Cancer Res , vol.51 , pp. 5760-5765
    • Stefanik, D.F.1    Rizkalla, L.R.2    Soi, A.3    Goldblatt, S.A.4    Rizkalla, W.M.5
  • 317
    • 0029082384 scopus 로고
    • Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes
    • Stein I, Neeman M, Shweiki D, Itin A, Keshet E (1995) Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes. Mol Cell Biol 15: 5363-5368
    • (1995) Mol Cell Biol , vol.15 , pp. 5363-5368
    • Stein, I.1    Neeman, M.2    Shweiki, D.3    Itin, A.4    Keshet, E.5
  • 318
    • 0030758108 scopus 로고    scopus 로고
    • Histopathologic and immunohistochemical prognostic factors in malignant gliomas
    • Stemmer-Rachamimov AO, Louis DN (1997) Histopathologic and immunohistochemical prognostic factors in malignant gliomas. Curr Opin Oncol 9: 230-234
    • (1997) Curr Opin Oncol , vol.9 , pp. 230-234
    • Stemmer-Rachamimov, A.O.1    Louis, D.N.2
  • 319
    • 0343550659 scopus 로고
    • EGF-stimulated tyrosine phosphorylation of p185neu: A potential model for receptor interactions
    • Stern DF, Kamps MP (1988) EGF-stimulated tyrosine phosphorylation of p185neu: a potential model for receptor interactions. EMBO J 7: 995-1001
    • (1988) EMBO J , vol.7 , pp. 995-1001
    • Stern, D.F.1    Kamps, M.P.2
  • 320
    • 0023661693 scopus 로고
    • Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
    • Stoker M, Gherardi E, Perryman M, Gray J (1987) Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 327: 239-242
    • (1987) Nature , vol.327 , pp. 239-242
    • Stoker, M.1    Gherardi, E.2    Perryman, M.3    Gray, J.4
  • 323
    • 0028064746 scopus 로고
    • Vascular permeability factor in brain metastases: Correlation with vasogenic brain edema and tumour angiogenesis
    • Strugar J, Rothbart D, Harrington W, Criscuolo GR (1994) Vascular permeability factor in brain metastases: correlation with vasogenic brain edema and tumour angiogenesis. J Neurosurg 81: 560-566
    • (1994) J Neurosurg , vol.81 , pp. 560-566
    • Strugar, J.1    Rothbart, D.2    Harrington, W.3    Criscuolo, G.R.4
  • 324
    • 0025114687 scopus 로고
    • Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas
    • Sugawa N, Ekstrand AJ, James CD, Collins VP (1990) Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas. Proc Natl Acad Sci USA 87: 8602-8606
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8602-8606
    • Sugawa, N.1    Ekstrand, A.J.2    James, C.D.3    Collins, V.P.4
  • 325
    • 0028335982 scopus 로고
    • Analysis of cytokine receptor messenger RNA expression in human glioblastoma cells and normal astrocytes by reverse-transcription polymerase chain reaction
    • Tada M, Diserens AC, Desbaillets I, De Tribolet N (1994) Analysis of cytokine receptor messenger RNA expression in human glioblastoma cells and normal astrocytes by reverse-transcription polymerase chain reaction. J Neurosurg 80: 1063-1073
    • (1994) J Neurosurg , vol.80 , pp. 1063-1073
    • Tada, M.1    Diserens, A.C.2    Desbaillets, I.3    De Tribolet, N.4
  • 326
    • 0026608650 scopus 로고
    • Correlation of basic fibroblast growth factor expression levels with the degree of malignancy and vascularity in human gliomas
    • Takahashi JA, Fukumoto M, Igarashi K, Oda Y, Kikuchi H, Hatunaka M (1992) Correlation of basic fibroblast growth factor expression levels with the degree of malignancy and vascularity in human gliomas. J Neurosurg 76: 792-298
    • (1992) J Neurosurg , vol.76 , pp. 792-1298
    • Takahashi, J.A.1    Fukumoto, M.2    Igarashi, K.3    Oda, Y.4    Kikuchi, H.5    Hatunaka, M.6
  • 327
  • 328
    • 0028318791 scopus 로고
    • Suramin, an anticancer and angiosuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase-type plasminogen activator
    • Takano S, Gately S, Neville ME, Herblin WF, Gross JL, Engelhard H, Perricone M et al (1994) Suramin, an anticancer and angiosuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase-type plasminogen activator. Cancer Res 54: 2654-2660
    • (1994) Cancer Res , vol.54 , pp. 2654-2660
    • Takano, S.1    Gately, S.2    Neville, M.E.3    Herblin, W.F.4    Gross, J.L.5    Engelhard, H.6    Perricone, M.7
  • 329
    • 0030772250 scopus 로고    scopus 로고
    • The autocrine loop of TGF-alpha/EGFR and brain tumours
    • Tang P, Steck PA, Yung WK (1997) The autocrine loop of TGF-alpha/EGFR and brain tumours. J Neurooncol 35: 303-314
    • (1997) J Neurooncol , vol.35 , pp. 303-314
    • Tang, P.1    Steck, P.A.2    Yung, W.K.3
  • 331
    • 0026713724 scopus 로고
    • Relationships between Ki-67 labelling index, amplification of the epidermal growth factor receptor gene, and prognosis in human glioblastomas
    • Torp SH, Helseth E, Dalen A, Unsgaard G (1992) Relationships between Ki-67 labelling index, amplification of the epidermal growth factor receptor gene, and prognosis in human glioblastomas. Acta Neurochir (Wien) 117: 182-186
    • (1992) Acta Neurochir (Wien) , vol.117 , pp. 182-186
    • Torp, S.H.1    Helseth, E.2    Dalen, A.3    Unsgaard, G.4
  • 332
    • 0029401049 scopus 로고
    • Platelet-derived growth factor in human glioma
    • Westermark B, Heldin CH, Nister M (1995) Platelet-derived growth factor in human glioma. Glia 15: 257-263
    • (1995) Glia , vol.15 , pp. 257-263
    • Westermark, B.1    Heldin, C.H.2    Nister, M.3
  • 333
    • 0020408487 scopus 로고
    • Effect of epidermal growth factor on membrane motility and cell locomotion in cultures of human clonal glioma cells
    • Westermark B, Magnusson A, Heldin CH (1982) Effect of epidermal growth factor on membrane motility and cell locomotion in cultures of human clonal glioma cells. J Neurosci Res 8: 491-507
    • (1982) J Neurosci Res , vol.8 , pp. 491-507
    • Westermark, B.1    Magnusson, A.2    Heldin, C.H.3
  • 334
    • 0026352044 scopus 로고
    • Receptors for platelet derived growth factor in human glioma cell lines and influence of suramin on cell proliferation
    • Westphal M, Ackermann E, Hoppe J, Hermann HD (1991) Receptors for platelet derived growth factor in human glioma cell lines and influence of suramin on cell proliferation. J Neurooncol 11: 207-213
    • (1991) J Neurooncol , vol.11 , pp. 207-213
    • Westphal, M.1    Ackermann, E.2    Hoppe, J.3    Hermann, H.D.4
  • 335
    • 0023874371 scopus 로고
    • Growth factors in cultured human glioma cells: Differential effects of FGF, EGF and PDGF
    • Westphal M, Brunken M, Rohde E, Hermann HD (1988) Growth factors in cultured human glioma cells: differential effects of FGF, EGF and PDGF. Cancer Lett 38: 283-296
    • (1988) Cancer Lett , vol.38 , pp. 283-296
    • Westphal, M.1    Brunken, M.2    Rohde, E.3    Hermann, H.D.4
  • 336
    • 0023857530 scopus 로고
    • Biological and karyotypic characterization of a new cell line derived from human gliosarcoma
    • Westphal M, Haensel M, Mueller D, Laas R, Kunzmann R, Rohde E, Koenig A et al (1988) Biological and karyotypic characterization of a new cell line derived from human gliosarcoma. Cancer Res 48: 731-740
    • (1988) Cancer Res , vol.48 , pp. 731-740
    • Westphal, M.1    Haensel, M.2    Mueller, D.3    Laas, R.4    Kunzmann, R.5    Rohde, E.6    Koenig, A.7
  • 337
    • 0028186567 scopus 로고
    • Epidermal growth factor receptor expression in human malignant glioma: In vitro and in vivo effects of application of monoclonal antibodies to the epidermal growth factor receptor
    • Westphal M, Hamel W, Zirkel D, Herrmann HD, Bilzer T, Reifenberger G, Schober R et al (1994) Epidermal growth factor receptor expression in human malignant glioma: in vitro and in vivo effects of application of monoclonal antibodies to the epidermal growth factor receptor. Recent Results Cancer Res 135: 171-184
    • (1994) Recent Results Cancer Res , vol.135 , pp. 171-184
    • Westphal, M.1    Hamel, W.2    Zirkel, D.3    Herrmann, H.D.4    Bilzer, T.5    Reifenberger, G.6    Schober, R.7
  • 340
    • 0022408560 scopus 로고
    • Epidermal growth factor receptors in the human glioblastoma cell line SF268 differ from those in epidermoid carcinoma cell line A431
    • Westphal M, Harsh GRt, Rosenblum ML, Hammonds RGJ (1985) Epidermal growth factor receptors in the human glioblastoma cell line SF268 differ from those in epidermoid carcinoma cell line A431. Biochem Biophys Res Commun 132: 284-289
    • (1985) Biochem Biophys Res Commun , vol.132 , pp. 284-289
    • Westphal, M.1    Harsh, G.Rt.2    Rosenblum, M.L.3    Hammonds, R.G.J.4
  • 341
    • 0024350129 scopus 로고
    • Growth factor biology and oncogene activation in human gliomas and their implications for specific therapeutic concepts
    • Westphal M, Herrmann HD (1989) Growth factor biology and oncogene activation in human gliomas and their implications for specific therapeutic concepts. Neurosurgery 25: 681-694
    • (1989) Neurosurgery , vol.25 , pp. 681-694
    • Westphal, M.1    Herrmann, H.D.2
  • 343
    • 0030832167 scopus 로고    scopus 로고
    • Cell surface localization and density of the tumour-associated variant of the epidermal growth factor receptor, EGFRvIII
    • Wikstrand CJ, McLendon RE, Friedman AH, Bigner DD (1997) Cell surface localization and density of the tumour-associated variant of the epidermal growth factor receptor, EGFRvIII. Cancer Res 57: 4130-4140
    • (1997) Cancer Res , vol.57 , pp. 4130-4140
    • Wikstrand, C.J.1    McLendon, R.E.2    Friedman, A.H.3    Bigner, D.D.4
  • 344
    • 0023429079 scopus 로고
    • Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
    • Wong AJ, Bigner SH, Bigner DD, Kinzler KW, Hamilton SR, Vogelstein B (1987) Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proc Natl Acad Sci USA 84: 6899-6903
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 6899-6903
    • Wong, A.J.1    Bigner, S.H.2    Bigner, D.D.3    Kinzler, K.W.4    Hamilton, S.R.5    Vogelstein, B.6
  • 346
    • 0023354032 scopus 로고
    • T cell suppressor factor from human glioblastoma cells is a 12.5-kd protein closely related to transforming growth factor-beta
    • Wrann M, Bodmer S, de Martin R, Siepl C, Hofer-Warbinek R, Frei K, Hofer E et al (1987) T cell suppressor factor from human glioblastoma cells is a 12.5-kd protein closely related to transforming growth factor-beta. EMBO J 6: 1633-1636
    • (1987) EMBO J , vol.6 , pp. 1633-1636
    • Wrann, M.1    Bodmer, S.2    De Martin, R.3    Siepl, C.4    Hofer-Warbinek, R.5    Frei, K.6    Hofer, E.7
  • 347
    • 0029114319 scopus 로고
    • Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma
    • Yamada N, Kato M, Yamashita H, Nister M, Miyazono K, Heldin CH, Funa K (1995) Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma. Int J Cancer 62: 386-392
    • (1995) Int J Cancer , vol.62 , pp. 386-392
    • Yamada, N.1    Kato, M.2    Yamashita, H.3    Nister, M.4    Miyazono, K.5    Heldin, C.H.6    Funa, K.7
  • 348
    • 0030814611 scopus 로고    scopus 로고
    • Astroglial expression of hepatocyte growth factor and hepatocyte growth factor activator in human brain tissues
    • Yamada T, Yoshiyama Y, Tsuboi Y, Shimomura T (1997) Astroglial expression of hepatocyte growth factor and hepatocyte growth factor activator in human brain tissues. Brain Res 762: 251-255
    • (1997) Brain Res , vol.762 , pp. 251-255
    • Yamada, T.1    Yoshiyama, Y.2    Tsuboi, Y.3    Shimomura, T.4
  • 349
    • 0023912033 scopus 로고
    • Amplification of the structurally and functionally altered epidermal growth factor receptor gene (c-erbB) in human brain tumours
    • Yamazaki H, Fukui Y, Ueyama Y, Tamaoki N, Kawamoto T, Taniguchi S, Shibuya M (1988) Amplification of the structurally and functionally altered epidermal growth factor receptor gene (c-erbB) in human brain tumours. Mol Cell Biol 8: 1816-1820
    • (1988) Mol Cell Biol , vol.8 , pp. 1816-1820
    • Yamazaki, H.1    Fukui, Y.2    Ueyama, Y.3    Tamaoki, N.4    Kawamoto, T.5    Taniguchi, S.6    Shibuya, M.7
  • 350
    • 0032522815 scopus 로고    scopus 로고
    • Inhibition of tumour growth by ribozyme-mediated suppression of aberrant epidermal growth factor receptor gene expression
    • Yamazaki H, Kijima H, Ohnishi Y, Abe Y, Oshika Y, Tsuchida T, Tokunaga T et al (1998) Inhibition of tumour growth by ribozyme-mediated suppression of aberrant epidermal growth factor receptor gene expression. J Natl Cancer Inst 90: 581-587
    • (1998) J Natl Cancer Inst , vol.90 , pp. 581-587
    • Yamazaki, H.1    Kijima, H.2    Ohnishi, Y.3    Abe, Y.4    Oshika, Y.5    Tsuchida, T.6    Tokunaga, T.7
  • 351
    • 0025111441 scopus 로고
    • A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor receptor gene in human brain tumours
    • Yamazaki H, Ohba Y, Tamaoki N, Shibuya M (1990) A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor receptor gene in human brain tumours. Jpn J Cancer Res 81: 773-779
    • (1990) Jpn J Cancer Res , vol.81 , pp. 773-779
    • Yamazaki, H.1    Ohba, Y.2    Tamaoki, N.3    Shibuya, M.4
  • 352
    • 0022541219 scopus 로고
    • Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors
    • Yarden Y, Escobedo JA, Kuang WJ, Yang-Feng TL, Daniel TO, Tremble PM, Chen EY et al (1986) Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature 323: 226-232
    • (1986) Nature , vol.323 , pp. 226-232
    • Yarden, Y.1    Escobedo, J.A.2    Kuang, W.J.3    Yang-Feng, T.L.4    Daniel, T.O.5    Tremble, P.M.6    Chen, E.Y.7
  • 353
    • 0026012736 scopus 로고
    • PDGF A-chain gene is expressed by mammalian neurons during development and in maturity
    • Yeh HJ, Ruit KG, Wang YX, Parks WC, Snider WD, Deuel TF (1991) PDGF A-chain gene is expressed by mammalian neurons during development and in maturity. Cell 64: 209-216
    • (1991) Cell , vol.64 , pp. 209-216
    • Yeh, H.J.1    Ruit, K.G.2    Wang, Y.X.3    Parks, W.C.4    Snider, W.D.5    Deuel, T.F.6
  • 354
    • 0029949160 scopus 로고    scopus 로고
    • Time-dependent vascular regression and permeability changes in established human tumour xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody
    • Yuan F, Chen Y, Dellian M, Safabakhsh N, Ferrara N, Jain RK (1996) Time-dependent vascular regression and permeability changes in established human tumour xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc Natl Acad Sci USA 93: 14765-14770
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14765-14770
    • Yuan, F.1    Chen, Y.2    Dellian, M.3    Safabakhsh, N.4    Ferrara, N.5    Jain, R.K.6
  • 355
    • 0025201337 scopus 로고
    • Immunohistochemical localization of basic fibroblast growth factor in astrocytomas
    • Zagzag D, Miller DC, Sato Y, Rifkin DB, Burstein DE (1990) Immunohistochemical localization of basic fibroblast growth factor in astrocytomas. Cancer Res 50: 7393-7398
    • (1990) Cancer Res , vol.50 , pp. 7393-7398
    • Zagzag, D.1    Miller, D.C.2    Sato, Y.3    Rifkin, D.B.4    Burstein, D.E.5
  • 356
    • 0029983510 scopus 로고    scopus 로고
    • Epidermal growth factor receptor: An independent predictor of survival in astrocytic tumours given definitive irradiation
    • Zhu A, Shaeffer J, Leslie S, Kolm P, El-Mahdi AM (1996) Epidermal growth factor receptor: an independent predictor of survival in astrocytic tumours given definitive irradiation. Int J Radiat Oncol Biol Phys 34: 809-815
    • (1996) Int J Radiat Oncol Biol Phys , vol.34 , pp. 809-815
    • Zhu, A.1    Shaeffer, J.2    Leslie, S.3    Kolm, P.4    El-Mahdi, A.M.5
  • 358
    • 0031975024 scopus 로고    scopus 로고
    • Expression and synthesis of insulin-like growth factor-binding proteins in human glioma cell lines
    • Zumkeller W, Muller D, Muller S, Gunther C, Westphal M (1998) Expression and synthesis of insulin-like growth factor-binding proteins in human glioma cell lines. Int J Oncol 12: 129-135
    • (1998) Int J Oncol , vol.12 , pp. 129-135
    • Zumkeller, W.1    Muller, D.2    Muller, S.3    Gunther, C.4    Westphal, M.5


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